Context-Induced Relapse of Conditioned Behavioral Responding to Ethanol Cues in Rats

Biological Psychiatry

Volumn 64, Issue 3, 2008, Pages 203-210

  Chaudhri, Nadia ^a   Sahuque, Lacey L ^a   Janak, Patricia H ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alcohol; cue reactivity; extinction; multiple contexts; Pavlovian discrimination; reinstatement; relapse; renewal

Indexed keywords

ALCOHOL; SUCROSE;

ANIMAL EXPERIMENT; ARTICLE; ASSOCIATION; AUDITORY STIMULATION; CONDITIONING; ENVIRONMENTAL FACTOR; INSTRUMENTAL CONDITIONING; MALE; NONHUMAN; PERCEPTIVE DISCRIMINATION; PRIORITY JOURNAL; RAT; RELAPSE; STIMULUS RESPONSE;

ACOUSTIC STIMULATION; ANIMALS; BEHAVIOR, ADDICTIVE; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONDITIONING, OPERANT; CUES; DISCRIMINATION (PSYCHOLOGY); DISEASE MODELS, ANIMAL; ETHANOL; EXTINCTION, PSYCHOLOGICAL; MALE; PHOTIC STIMULATION; RATS; RATS, LONG-EVANS; RECURRENCE;

EID: 46249132112     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2008.03.007     Document Type: Article

References (52)

1. Ludwig A.M. Pavlov's "bells" and alcohol craving. Addict Behav 11 (1986) 87-91
2. Everitt B.J., Dickinson A., and Robbins T.W. The neuropsychological basis of addictive behaviour. Brain Res Brain Res Rev 36 (2001) 129-138
3. Weiss F. Neurobiology of craving, conditioned reward and relapse. Curr Opin Pharmacol 5 (2005) 9-19
4. Fox H.C., Bergquist K.L., Hong K.I., and Sinha R. Stress-induced and alcohol cue-induced craving in recently abstinent alcohol-dependent individuals. Alcohol Clin Exp Res 31 (2007) 395-403
5. Newlin D.B., Hotchkiss B., Cox W.M., Rauscher F., and Li T.K. Autonomic and subjective responses to alcohol stimuli with appropriate control stimuli. Addict Behav 14 (1989) 625-630
6. Litt M.D., and Cooney N.L. Inducing craving for alcohol in the laboratory. Alcohol Res Health 23 (1999) 174-178
7. Reid M.S., Flammino F., Starosta A., Palamar J., and Franck J. Physiological and subjective responding to alcohol cue exposure in alcoholics and control subjects: Evidence for appetitive responding. J Neural Transm 113 (2006) 1519-1535
8. Niaura R.S., Rohsenow D.J., Binkoff J.A., Monti P.M., Pedraza M., and Abrams D.B. Relevance of cue reactivity to understanding alcohol and smoking relapse. J Abnorm Psychol 97 (1988) 133-152
9. Rohsenow D.J., Monti P.M., Rubonis A.V., Sirota A.D., Niaura R.S., Colby S.M., et al. Cue reactivity as a predictor of drinking among male alcoholics. J Consult Clin Psychol 62 (1994) 620-626
10. Cooney N.L., Litt M.D., Morse P.A., Bauer L.O., and Gaupp L. Alcohol cue reactivity, negative-mood reactivity, and relapse in treated alcoholic men. J Abnorm Psychol 106 (1997) 243-250
11. Litt M.D., Cooney N.L., and Morse P. Reactivity to alcohol-related stimuli in the laboratory and in the field: Predictors of craving in treated alcoholics. Addiction 95 (2000) 889-900
12. Laberg J.C. What is presented, and what prevented, in cue exposure and response prevention with alcohol dependent subjects?. Addict Behav 15 (1990) 367-386
13. Marlatt G.A. Cue exposure and relapse prevention in the treatment of addictive behaviors. Addict Behav 15 (1990) 395-399
14. Rohsenow D.J., Niaura R.S., Childress A.R., Abrams D.B., and Monti P.M. Cue reactivity in addictive behaviors: Theoretical and treatment implications. Int J Addict 25 (1990) 957-993
15. Hammersley R. Cue exposure and learning theory. Addict Behav 17 (1992) 297-300
16. Monti P.M., Rohsenow D.J., Rubonis A.V., Niaura R.S., Sirota A.D., Colby S.M., et al. Cue exposure with coping skills treatment for male alcoholics: A preliminary investigation. J Consult Clin Psychol 61 (1993) 1011-1019
17. Drummond D.C., and Glautier S. A controlled trial of cue exposure treatment in alcohol dependence. J Consult Clin Psychol 62 (1994) 809-817
18. Drummond D.C. What does cue-reactivity have to offer clinical research?. Addiction 95 suppl 2 (2000) S129-S144
19. Carter B.L., and Tiffany S.T. Meta-analysis of cue-reactivity in addiction research. Addiction 94 (1999) 327-340
20. Conklin C.A., and Tiffany S.T. Applying extinction research and theory to cue-exposure addiction treatments. Addiction 97 (2002) 155-167
21. Bouton M.E., and Bolles R.C. Role of conditioned contextual stimuli in reinstatement of extinguished fear. J Exp Psychol Anim Behav Process 5 (1979) 368-378
22. Bouton M.E. Context and ambiguity in the extinction of emotional learning: Implications for exposure therapy. Behav Res Ther 26 (1988) 137-149
23. Bouton M.E., and Peck C.A. Context effects on conditioning, extinction and reinstatement in an appetitive conditioning paradigm. Anim Learn Behav 17 (1989) 188-198
24. Vansteenwegen D., Hermans D., Vervliet B., Francken G., Beckers T., Baeyens F., and Eelen P. Return of fear in a human differential conditioning paradigm caused by a return to the original acquistion context. Behav Res Ther 43 (2005) 323-336
25. Bouton M.E., Westbrook R.F., Corcoran K.A., and Maren S. Contextual and temporal modulation of extinction: Behavioral and biological mechanisms. Biol Psychiatry 60 (2006) 352-360
26. Bouton M.E. Context and behavioral processes in extinction. Learn Mem 11 (2004) 485-494
27. Conklin C.A. Environments as cues to smoke: Implications for human extinction-based research and treatment. Exp Clin Psychopharmacol 14 (2006) 12-19
28. Bossert J.M., Gray S.M., Lu L., and Shaham Y. Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking. Neuropsychopharmacology 31 (2006) 2197-2209
29. Bossert J.M., Liu S.Y., Lu L., and Shaham Y. A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking. J Neurosci 24 (2004) 10726-10730
30. Crombag H.S., Grimm J.W., and Shaham Y. Effect of dopamine receptor antagonists on renewal of cocaine seeking by reexposure to drug-associated contextual cues. Neuropsychopharmacology 27 (2002) 1006-1015
31. Crombag H.S., and Shaham Y. Renewal of drug seeking by contextual cues after prolonged extinction in rats. Behav Neurosci 116 (2002) 169-173
32. Burattini C., Gill T.M., Aicardi G., and Janak P.H. The ethanol self-administration context as a reinstatement cue: Acute effects of naltrexone. Neuroscience 139 (2006) 877-887
33. Tsiang M.T., and Janak P.H. Alcohol seeking in C57BL/6 mice induced by conditioned cues and contexts in the extinction-reinstatement model. Alcohol 38 (2006) 81-88
34. Zironi I., Burattini C., Aicardi G., and Janak P.H. Context is a trigger for relapse to alcohol. Behav Brain Res 167 (2006) 150-155
35. Fuchs R.A., Eaddy J.L., Su Z.I., and Bell G.H. Interactions of the basolateral amygdala with the dorsal hippocampus and dorsomedial prefrontal cortex regulate drug context-induced reinstatement of cocaine-seeking in rats. Eur J Neurosci 26 (2007) 487-498
36. Fuchs R.A., Evans K.A., Ledford C.C., Parker M.P., Case J.M., Mehta R.A., and See R.E. The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats. Neuropsychopharmacology 30 (2005) 296-309
37. Gunther L.M., Denniston J.C., and Miller R.R. Conducting exposure treatment in multiple contexts can prevent relapse. Behav Res Ther 36 (1998) 75-91
38. Vansteenwegen D., Vervliet B., Iberico C., Baeyens F., Van den Bergh O., and Hermans D. The repeated confrontation with videotapes of spiders in multiple contexts attenuates renewal of fear in spider-anxious students. Behav Res Ther 45 (2007) 1169-1179
39. Institute of Laboratory Animal Resources Commission on Life Sciences, and National Research Council. Guide of the Care and Use of Laboratory Animals (1996), National Academy Press, Washington, DC
40. Heyman G.M. Preference for saccharin-sweetened alcohol relative to isocaloric sucrose. Psychopharmacology (Berl) 129 (1997) 72-78
41. Nakajima S., Tanaka D., Urushihara K., and Imada H. Renewal of extinguished lever-press responses upon return to the training context. Learn Motiv 31 (2000) 416-431
42. Holland P.C. Differential effects of omission contingencies on various components of Pavlovian appetitive conditioned responding in rats. J Exp Psychol Anim Behav Process 5 (1979) 178-193
43. Kearns D.N., and Weiss S.J. Contextual renewal of cocaine seeking in rats and its attenuation by the conditioned effects of an alternative reinforcer. Drug Alcohol Depend 90 (2007) 193-202
44. Corbit L.H., and Janak P.H. Ethanol-associated cues produce general pavlovian-instrumental transfer. Alcohol Clin Exp Res 31 (2007) 766-774
45. Chelonis J.J., Calton J.L., Hart J.A., and Schachtman T.R. Attenuation of the renewal effect by extinction in multiple contexts. Learn Motiv 30 (1999) 1-14
46. Bouton M.E., Garcia-Gutierrez A., Zilski J., and Moody E.W. Extinction in multiple contexts does not necessarily make extinction less vulnerable to relapse. Behav Res Ther 44 (2006) 983-994
47. Neumann D.L., Lipp O.V., and Cory S.E. Conducting extinction in multiple contexts does not necessarily attenuate the renewal of shock expectancy in a fear-conditioning procedure with humans. Behav Res Ther 45 (2007) 385-394
48. Kelley A.E., and Berridge K.C. The neuroscience of natural rewards: Relevance to addictive drugs. J Neurosci 22 (2002) 3306-3311
49. Kelley A.E., Schiltz C.A., and Landry C.F. Neural systems recruited by drug- and food-related cues: Studies of gene activation in corticolimbic regions. Physiol Behav 86 (2005) 11-14
50. Gill K., Amit Z., and Smith B.R. Alcohol as a food: A commentary on Richter. Physiol Behav 60 (1996) 1485-1490
51. Ciccocioppo R., Martin-Fardon R., and Weiss F. Stimuli associated with a single cocaine experience elicit long-lasting cocaine-seeking. Nat Neurosci 7 (2004) 495-496
52. Krank M.D. Pavlovian conditioning with ethanol: Sign-tracking (autoshaping), conditioned incentive, and ethanol self-administration. Alcohol Clin Exp Res 27 (2003) 1592-1598