Dietary glutamine supplementation increases the activity of peritoneal macrophages and hemopoiesis in early-weaned mice inoculated with mycobacterium bovis bacillus Calmette-Guérin

Journal of Nutrition

Volumn 138, Issue 7, 2008, Pages 1343-1348

  Rogero, Marcelo Macedo ^a   Tirapegui, Julio ^a   Vinolo, Marco Aurélio Ramirez ^a   Borges, Maria Carolina ^a   De Castro, Inar Alves ^a   De Oliveira Fires, Ivanir Santana ^a   Borelli, Primavera ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE AMMONIA LIGASE; GLUTAMINE; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; BCG VACCINE;

AMINO ACID COMPOSITION; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; HEMATOPOIESIS; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MALE; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PERITONEUM MACROPHAGE; SPLEEN; ANIMAL; ARTIFICIAL MILK; DRUG EFFECT; HUMAN; IMMUNOLOGY; INFANT; METABOLISM; MILK; NEWBORN; WEANING;

MUS; MYCOBACTERIUM BOVIS; MYCOBACTERIUM BOVIS BCG;

ANIMALS; ANIMALS, NEWBORN; BCG VACCINE; DIETARY SUPPLEMENTS; GLUTAMINE; HEMATOPOIESIS; HUMANS; INFANT; INFANT FORMULA; INFANT, NEWBORN; MACROPHAGES, PERITONEAL; MALE; MICE; MILK; WEANING;

EID: 46249122122     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/138.7.1343     Document Type: Article

References (46)

1. Kramer MS, Kakuma R. The optimal duration of exclusive breastfeeding: a systematic review. Adv Exp Med Biol. 2004;554:63-77.
2. Gartner LM, Morton J, Lawrence RA, Naylor AJ, O'Hare D, Schanler RJ, Eidelman AI. American Academy of Pediatrics Section on Breastfeeding. Breastfeeding and the use of human milk. Pediatrics. 2005; 115:496-506.
3. Labbok MH, Clark D, Goldman AS. Breastfeeding: maintaining an irreplaceable immunological resource. Nat Rev Immunol. 2004;4: 565-72.
4. Dewey KG, Heinig MJ, Nommsen-Rivers LA. Differences in morbidity between breast-fed and formula-fed infants, J Pediatr. 1995;126: 696-702.
5. Jones G, Steketee RW, Black RE, Bhutta ZA, Morris SS, Bellagio Child Survival Study Group. How many child deaths can we prevent this year? Lancet. 2003-362:65-71.
6. Levy J. Immunonutrition: the pediatric experience. Nutrition. 1998;14: 641-7.
7. Filteau SM. Role of breast-feeding in managing malnutrition and infectious disease. Proc Nutr Soc. 2000;59:565-72.
8. Davis TA, Nguyen HV, Garcia-Bravo R, Fiorotto ML, Jackson EM, Lewis DS, Lee DR, Reeds PJ. Amino acid composition of human milk is not unique. J Nutr. 1994;124:1126-32.
9. Rassin DK, Sturman JA, Guall GE. Taurine and other free amino acids in milk of man and other mammals. Early Hum Dev. 1978;2:1-13.
10. Agostoni C, Carratu B, Boniglia C, Riva E, Sanzini E. Free glutamine and glutamic acid increase in milk through a three-month lactation period. J Pediatr Gastroenterol Nutr. 2000;31:508-12.
11. Flaring UB, Rooyackers OE, Wernerman J, Hammarqvist E Glutamine attenuates post-traumatic glutathione depletion in human muscle. Clin Sci. 2003;104:275-82.
12. Lacey JM, Wilmore DW. Is glutamine a conditionally essential amino acid? Nutr Rev. 1990;48:297-309.
13. Wallace C, Keast D. Glutamine and macrophages function. Metabolism. 1992;41:1016-20.
14. Bellows CF, Jaffe BM. Glutamine is essential for nitric oxide synthesis by murine macrophages. J Surg Res. 1999;86:213-9.
15. Yassad A, Husson A, Bion A, Lavoinne A. Synthesis of interleukin lbeta and interleukin 6 by stimulated rat peritoneal macrophages: modulation by glutamine. Cytokine. 2000; 12:1288-91.
16. Yassad A, Lavoinne A, Bion A, Daveau M, Husson A. Glutamine accelerates IL-6 production by rat peritoneal macrophages in culture. FEBS Lett. 1997;413:81-4.
17. Murphy C, Newshohne P. Macrophage-mediated lysis of a β-cell line, TNF-α release from BCG-actived murine macrophages and IL-8 release from human monocytes are dependent on extracelular glutamine concentration and glutamine metabolism. Clin Sci. 1999;96:89-97.
18. 2 metabolism. Evidence for cyclic AMP-dependent protein kinase mediated inhibition of glucose-6-phosphate dehydrogenase and activation of NADP+-dependent 'malic' enzyme. Biochem J. 1995;310:709-14.
19. Newsholme P. Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection? J Nutr. 2001;131:S2515-22.
20. Dass PD, Murdoch FE, Wu MC. Glutamine promotes colony formation in bone marrow and HL-60 cells, accelerates myeloid differentiation in induced HL-60 cells. In Vitro. 1984;20:869-75.
21. Ziegler TR. Glutamine supplementation in bone marrow transplantation. Br J Nutr. 2002;87:S9-15.
22. Ziegler TR, Bye RL, Persinger RL, Young LS, Antin JH, Wilmore DW. Effects of glutamine supplementation on circulating lymphocytes after bone marrow transplantation: a pilot study. Am J Med Sci. 1998;315:4-10.
23. Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition "ad hoc" writing committee on the reformulation of the AIN-76a rodent diet. J Nutr. 1993;123:1939-51.
24. Lund P. Determination of glutamine with glutaminase and glutamate dehydrogenase. In: Bergmeyer HU, Grassl M, editors. Methods of enzymatic analysis, Weinheim: Verlag Chemie, 1985. p. 1719-22.
25. Sahlin K, Katz A, Broberg S, Tricarboxylic acid cycle intermediates in human muscle during prolonged exercise. Am J Physiol. 1990;259:C834-41.
26. Minet R, Villie F, Marcollet M, Meynial-Denis D, Cynober L. Measurement of glutamine synthetase activity in rat muscle by a colorimetric assay. Clin Chim Acta. 1997;268:121-32.
27. Dacie JV, Lewis SM. Practical haematology. Edinburgh: Churchill Livingstone; 1995.
28. Pick E, Mizel D. Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader. J Immunol Methods. 1981;46: 211-26.
29. Rabinovitch M, Destefano MJ. Macrophage spreading in vitro. I. Inducers of spreading. Exp Cell Res. 1973;77:323-34.
30. Sasada M, Johnston RB. Macrophage microbicidal activity: correlation between phagocytosis-associated oxidative metabolism and the killing of Candida by macrophage. J Exp Med. 1980;152:85-98.
31. Sampaio SC, Sousa-e-Silva MC, Borelli P, Curi R, Cury Y. Crotalus durissus terrificus snake venom regulates macrophage metabolism and function. J Leukoc Biol. 2001;70:551-8.
32. Bradford MM. A rapid and sensitive method for the quantitation of microgram of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-54.
33. Reeds PJ, Burrin DG, Davis TA, Fiorotto ML, Stoll B, Goudoever JBV. Protein nutrition of the neonate. Proc Nutr Soc. 2000;59:87-97.
34. Yoo SS, Field CJ, Mcburney MI. Glutamine supplementation maintains intramuscular glutamine concentrations and normalizes lymphocyte function in early weaned pigs. J Nutr. 1997;127:2253-9.
35. Parimi PS, Kalhan SC. Glutamine supplementation in the newborn infant. Semin Fetal Neonatal Med. 2007;12:19-25.
36. Windmueller HG. Glutamine utilization by the small intestine, Adv Enzymol Reiat Areas Mol Biol. 1982;53:201-37.
37. Neu J. Glutamine in the fetus and critically ill low birth weight neonate: metabolism and mechanism of action. J Nutr. 2001;131:S2585-9.
38. Becker RM, Wu G, Galanko JA, Chen W, Maynor AR, Bose CL, Rhoads JM. Reduced serum amino acid concentrations in infants with necrotizing enterocolitis. J Pediatr. 2000;137:785-93.
39. Bulus N, Cersosimo E, Ghishan F, Abumrad NN. Physiologic importance of glutamine. Metabolism. 1989;38:1-5.
40. Ehasen MM, Winkler W, Jordan V, Pokar M, Marchetti M, Roth E, Alhnaier G, Oehler R. Adaptive cellular mechanisms in response to glutamine-starvation. Front Biosci. 2006;11:3199-211.
41. Costa Rosa LFBP, Safi DA, Curi R. Effect of thioglycollate and BCG stimuli on glucose and glutamine metabolism in rat macrophages. J Leukoc Biol. 1994;56:10-4.
42. Wells SM, Kew S, Yaqoob P, Wallace FA, Calder PC. Dietary glutamine enhances cytokine production by murine macrophages. Nutrition. 1999; 15:881-4.
43. Komatsu W, Mawatari K, Miura Y, Yagasaki K. Restoration by dietary glutamine of reduced tumor necrosis factor production in a low-protein-diet-fed rat model. Biosci Biotechnol Biochem. 2007;71:352-7.
44. Louie A, Baltch AL, Smith RP, Franke MA, Ritz WJ, Singh JK, Gordon MA. Tumor necrosis factor alpha has a protective role in a murine model of systemic candidiasis. Infect Imrnun. 1994;62;2761-72.
45. Newsholme P, Costa Rosa LFBP, Newsholme EA, Curi R. The importance of fuel metabolism to macrophage function. Cell Biochem Funct. 1996;14:1-10.
46. Murphy C, Newsholme P. Importance of glutamine metabolism in murine macrophages and human monocytes to L-arginine biosynthesis and rates of nitrite or urea production. Clin Sci. 1998;95:397-4107.