Discovering dynamic characteristics of biochemical pathways using geometric patterns among parameter-parameter dependencies in differential equations

New Generation Computing

Volumn 25, Issue 4, 2007, Pages 425-441

  Azuma, Ryuzo ^a   Umetsu, Ryo ^a   Ohki, Shingo ^a   Konishi, Fumikazu ^a   Yoshikawa, Sumi ^a   Konagaya, Akihiko ^a   Matsumura, Kazumi ^b  

^a RIKEN YOKOHAMA INSTITUTE   (Japan)

^b DAIICHI PURE CHEMICALS CO LTD   (Japan)

Author keywords

Grid computing; Mathematical models; Pharmacokinetics; Simulation; Visualization

Indexed keywords

BESSEL FUNCTIONS; BIOINFORMATICS; CHEMOTHERAPY; CURVES (ROAD); DIFFERENCE EQUATIONS; DIFFERENTIAL EQUATIONS; DIFFERENTIATION (CALCULUS); DRUG DELIVERY; DRUG DOSAGE; DRUG PRODUCTS; DYNAMIC ANALYSIS; DYNAMIC MODELS; DYNAMIC PROGRAMMING; EXTRAPOLATION; FUNCTIONS; GEOMETRY; MATHEMATICAL TECHNIQUES; TWO DIMENSIONAL;

(001) PARAMETER; AREA UNDER THE CURVE (AUC); BIOCHEMICAL PATHWAYS; CANCER DRUGS; COMPUTATIONAL RESOURCES; CYBERINFRASTRUCTURE (CI); DYNAMIC CHARACTERISTICS; DYNAMIC SYSTEMS; GEOMETRIC PATTERNS; GEOMETRICAL PATTERNS; IRINOTECAN; MEAN RESIDENCE TIME (MRT); METABOLIC PATHWAYS; MOMENT CURVE; NOVE L APPROACH; OPEN BIOINFORMATICS GRID (OBIGRID); PARAMETER VALUES; TWO-DIMENSIONAL (2D); WIDE-RANGE;

MATHEMATICAL MODELS;

EID: 46249114675     PISSN: 02883635     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00354-007-0027-3     Document Type: Article

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