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Volumn 17, Issue 14, 2008, Pages 2160-2171

The S18Y polymorphic variant of UCH-L1 confers an antioxidant function to neuronal cells

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE DECARBOXYLASE; PROTEASOME; SERINE; TYROSINE; UBIQUITIN; UBIQUITIN THIOLESTERASE; UBIQUITIN THIOLESTERASE L1;

EID: 46249113267     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn115     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • Dauer, W. and Przedborski, S. (2003) Parkinson's disease: Mechanisms and models. Neuron, 39, 889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 2
    • 36448964545 scopus 로고    scopus 로고
    • Parkinson disease, 10 years after its genetic revolution: Multiple clues to a complex disorder
    • Klein, C. and Schlossmacher, M.G. (2007) Parkinson disease, 10 years after its genetic revolution: Multiple clues to a complex disorder. Neurology, 69, 2093-2104.
    • (2007) Neurology , vol.69 , pp. 2093-2104
    • Klein, C.1    Schlossmacher, M.G.2
  • 6
    • 0033544368 scopus 로고    scopus 로고
    • Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson's disease
    • Maraganore, D.M., Farrer, M.J., Hardy, J.A., Lincoln, S.J., McDonnell, S.K., Rocca, W.A. et al. (1999) Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson's disease. Neurology, 53, 1858-1860.
    • (1999) Neurology , vol.53 , pp. 1858-1860
    • Maraganore, D.M.1    Farrer, M.J.2    Hardy, J.A.3    Lincoln, S.J.4    McDonnell, S.K.5    Rocca, W.A.6
  • 7
    • 0035881339 scopus 로고    scopus 로고
    • A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson's disease in a Japanese population
    • Satoh, I and Kuroda, Y. (2001) A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson's disease in a Japanese population. J. Neurol. Sci., 189, 113-117.
    • (2001) J. Neurol. Sci , vol.189 , pp. 113-117
    • Satoh, I.1    Kuroda, Y.2
  • 8
    • 34347257768 scopus 로고    scopus 로고
    • S19Y in ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) associated with decreased risk of Parkinson's disease in Sweden
    • Carmine Belin, A., Westerlund, M., Bergman, O., Nissbrandt, H., Lind, C., Sydow, O., Galter, D. et al. (2007) S19Y in ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) associated with decreased risk of Parkinson's disease in Sweden. Parkinsonism Relat. Disord., 13 295-298.
    • (2007) Parkinsonism Relat. Disord , vol.13 , pp. 295-298
    • Carmine Belin, A.1    Westerlund, M.2    Bergman, O.3    Nissbrandt, H.4    Lind, C.5    Sydow, O.6    Galter, D.7
  • 10
    • 34547535639 scopus 로고    scopus 로고
    • The functions of UCH-L1 and its relation to neurodegenerative diseases
    • Setsuie, R. and Wada, K. (2007) The functions of UCH-L1 and its relation to neurodegenerative diseases. Neurochem. Int., 51, 105-111.
    • (2007) Neurochem. Int , vol.51 , pp. 105-111
    • Setsuie, R.1    Wada, K.2
  • 11
    • 0037131567 scopus 로고    scopus 로고
    • The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
    • Liu, Y., Fallon, L., Lashuel, H.A., Liu, Z. and Lansbury, P.T., Jr (2002) The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell, 111, 209-218.
    • (2002) Cell , vol.111 , pp. 209-218
    • Liu, Y.1    Fallon, L.2    Lashuel, H.A.3    Liu, Z.4    Lansbury Jr, P.T.5
  • 14
  • 15
    • 3142724742 scopus 로고    scopus 로고
    • UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease
    • Ardley, H.C., Scott, G.B., Rose, S.A., Tan, N.G. and Robinson, P.A. (2004) UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease. J. Neurochem., 90, 379-391.
    • (2004) J. Neurochem , vol.90 , pp. 379-391
    • Ardley, H.C.1    Scott, G.B.2    Rose, S.A.3    Tan, N.G.4    Robinson, P.A.5
  • 17
    • 34547399497 scopus 로고    scopus 로고
    • Differential effects of Parkin and its mutants on protein aggregation, the ubiquitin-proteasome system, and neuronal cell death in human neuroblastoma cells
    • Kyratzi, E., Pavlaki, M., Kontostavlaki, D., Rideout, H.J. and Stefanis, L. (2007) Differential effects of Parkin and its mutants on protein aggregation, the ubiquitin-proteasome system, and neuronal cell death in human neuroblastoma cells. J. Neurochem., 102, 1292-1303.
    • (2007) J. Neurochem , vol.102 , pp. 1292-1303
    • Kyratzi, E.1    Pavlaki, M.2    Kontostavlaki, D.3    Rideout, H.J.4    Stefanis, L.5
  • 18
    • 0033178444 scopus 로고    scopus 로고
    • Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
    • Stefanis, L., Park, D.S., Friedman, W.J. and Greene, L.A. (1999) Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons. J. Neurosci.; 19, 6235-6247.
    • (1999) J. Neurosci , vol.19 , pp. 6235-6247
    • Stefanis, L.1    Park, D.S.2    Friedman, W.J.3    Greene, L.A.4
  • 19
    • 0037713489 scopus 로고    scopus 로고
    • The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: A tool to explore the pathogenesis of Parkinson's disease
    • Przedborski, S. and Vila, M. (2003) The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: A tool to explore the pathogenesis of Parkinson's disease. Ann. NY Acad. Sci. 991, 189-198.
    • (2003) Ann. NY Acad. Sci , vol.991 , pp. 189-198
    • Przedborski, S.1    Vila, M.2
  • 20
    • 0348010284 scopus 로고    scopus 로고
    • Mechanisms of caspase-independent neuronal death: Energy depletion and free radical generation
    • Lang-Rollin, I.C., Rideout, H.J., Noticewala, M. and Stefanis, L. (2003) Mechanisms of caspase-independent neuronal death: Energy depletion and free radical generation. J. Neurosci., 23, 11015-11025.
    • (2003) J. Neurosci , vol.23 , pp. 11015-11025
    • Lang-Rollin, I.C.1    Rideout, H.J.2    Noticewala, M.3    Stefanis, L.4
  • 22
    • 0028027308 scopus 로고
    • Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain
    • Treier, M., Staszewski, L.M. and Bohmann, D. (1994) Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain. Cell 78, 787-798.
    • (1994) Cell , vol.78 , pp. 787-798
    • Treier, M.1    Staszewski, L.M.2    Bohmann, D.3
  • 23
    • 0029068172 scopus 로고
    • Ubiquitinylation is not an absolute requirement for degradation of c-Jun protein by the 26 S proteasome
    • Jariel-Encontre, I., Pariat, M., Martin, F., Carillo, S., Salvat, C., Piechaczyk, M. et al. (1995) Ubiquitinylation is not an absolute requirement for degradation of c-Jun protein by the 26 S proteasome. J. Biol. Chem., 270, 11623-11627.
    • (1995) J. Biol. Chem , vol.270 , pp. 11623-11627
    • Jariel-Encontre, I.1    Pariat, M.2    Martin, F.3    Carillo, S.4    Salvat, C.5    Piechaczyk, M.6
  • 24
    • 0034956888 scopus 로고    scopus 로고
    • Ubiquitin C-terminal hydrolase-L1 (PGP9.5) expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines, neurotropbic factors or heat stress
    • Satoh, J.I. and Kuroda, Y. (2001) Ubiquitin C-terminal hydrolase-L1 (PGP9.5) expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines, neurotropbic factors or heat stress. Neuropathol. Appl. Neurobiol., 27, 95-104.
    • (2001) Neuropathol. Appl. Neurobiol , vol.27 , pp. 95-104
    • Satoh, J.I.1    Kuroda, Y.2
  • 25
    • 34548625019 scopus 로고    scopus 로고
    • Epidemiologic studies of environmental exposures in Parkinson's disease
    • Elbaz, A. and Tranchant, C. (2007) Epidemiologic studies of environmental exposures in Parkinson's disease. J. Neurol. Sci., 262, 37-44.
    • (2007) J. Neurol. Sci , vol.262 , pp. 37-44
    • Elbaz, A.1    Tranchant, C.2
  • 26
    • 34249845272 scopus 로고    scopus 로고
    • Reversible monoubiquitination regulates the Parkinson disease-associated ubiquitin hydrolase UCH-L1
    • Meray, R.K. and Lansbury, P.T., Jr (2007) Reversible monoubiquitination regulates the Parkinson disease-associated ubiquitin hydrolase UCH-L1. J. Biol. Chem., 282, 10567-10575.
    • (2007) J. Biol. Chem , vol.282 , pp. 10567-10575
    • Meray, R.K.1    Lansbury Jr, P.T.2
  • 28
    • 4644263753 scopus 로고    scopus 로고
    • Two closely related ubiquitin C-terminal hydrolase isozymes function as reciprocal modulators of germ cell apoptosis in cryptorchid testis
    • Kwon, J., Wang, Y.L., Setsuie, R., Sekiguchi, S., Sato, Y., Sakurai, M., Noda, M., Aoki, S., Yoshikawa, Y., Wada, K. et al. (2004) Two closely related ubiquitin C-terminal hydrolase isozymes function as reciprocal modulators of germ cell apoptosis in cryptorchid testis. Am. J. Pathol., 165, 1367-1374.
    • (2004) Am. J. Pathol , vol.165 , pp. 1367-1374
    • Kwon, J.1    Wang, Y.L.2    Setsuie, R.3    Sekiguchi, S.4    Sato, Y.5    Sakurai, M.6    Noda, M.7    Aoki, S.8    Yoshikawa, Y.9    Wada, K.10
  • 29
    • 1842581669 scopus 로고    scopus 로고
    • Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases
    • Choi, J., Levey, A.I., Weintraub, S.T., Rees, H.D., Gearing, M., Chin, L.S., Li, L. et al. (2004) Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. J. Biol. Chem. 279, 13256-13264.
    • (2004) J. Biol. Chem , vol.279 , pp. 13256-13264
    • Choi, J.1    Levey, A.I.2    Weintraub, S.T.3    Rees, H.D.4    Gearing, M.5    Chin, L.S.6    Li, L.7
  • 30
  • 31
    • 36849001303 scopus 로고    scopus 로고
    • The role of ubiquitin C-terminal hydrolase L1 in neurodegenerative disorders
    • Gong, B. and Leznik, E. (2007) The role of ubiquitin C-terminal hydrolase L1 in neurodegenerative disorders. Drug News Perspect., 20, 365-370.
    • (2007) Drug News Perspect , vol.20 , pp. 365-370
    • Gong, B.1    Leznik, E.2
  • 32
    • 0037008355 scopus 로고    scopus 로고
    • Mutation analysis and association studies of the ubiquitin carboxy-terminal hydrolase L1 gene in Huntington's disease
    • Naze, P., Vuillaume, I., Destee, A., Pasquier, F. and Sablonniere, B. (2002) Mutation analysis and association studies of the ubiquitin carboxy-terminal hydrolase L1 gene in Huntington's disease. Neurosci. Lett., 328, 1-4.
    • (2002) Neurosci. Lett , vol.328 , pp. 1-4
    • Naze, P.1    Vuillaume, I.2    Destee, A.3    Pasquier, F.4    Sablonniere, B.5
  • 33
    • 33646869931 scopus 로고    scopus 로고
    • Genetic association between Ubiquitin Carboxy-terminal Hydrolase-L1 gene S18Y polymorphism and sporadic Alzheimer's disease in a Chinese Han population
    • Xue, S. and Jia, J. (2006) Genetic association between Ubiquitin Carboxy-terminal Hydrolase-L1 gene S18Y polymorphism and sporadic Alzheimer's disease in a Chinese Han population. Brain Res., 1087, 28-32.
    • (2006) Brain Res , vol.1087 , pp. 28-32
    • Xue, S.1    Jia, J.2
  • 34
    • 0035894855 scopus 로고    scopus 로고
    • Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
    • Stefanis, L., Larsen, K.E., Rideout, H.J., Sulzer, D. and Greene, L.A. (2001) Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J. Neurosci., 21, 9549-9560.
    • (2001) J. Neurosci , vol.21 , pp. 9549-9560
    • Stefanis, L.1    Larsen, K.E.2    Rideout, H.J.3    Sulzer, D.4    Greene, L.A.5
  • 36
    • 0035900612 scopus 로고    scopus 로고
    • Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint-and of p53 induction
    • Rideout, H.J., Zang, E., Yeasmin, M., Gordon, R., Jabado, O., Park, D.S., Stefanis, L. et al. (2001) Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint-and of p53 induction. Neuroscience 107, 339-352.
    • (2001) Neuroscience , vol.107 , pp. 339-352
    • Rideout, H.J.1    Zang, E.2    Yeasmin, M.3    Gordon, R.4    Jabado, O.5    Park, D.S.6    Stefanis, L.7
  • 37
    • 0036432029 scopus 로고    scopus 로고
    • Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination
    • Rideout, H.J. and Stefanis, L. (2002) Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination. Mol. Cell Neurosci., 21, 223-238.
    • (2002) Mol. Cell Neurosci , vol.21 , pp. 223-238
    • Rideout, H.J.1    Stefanis, L.2
  • 38
    • 0025939423 scopus 로고
    • Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms
    • Rukenstein, A., Rydel, R.E. and Greene, L.A. (1991) Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J. Neurosci., 11, 2552-2563.
    • (1991) J. Neurosci , vol.11 , pp. 2552-2563
    • Rukenstein, A.1    Rydel, R.E.2    Greene, L.A.3
  • 40
    • 0026554428 scopus 로고
    • Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
    • LeBel, C.P., Ischiropoulos, H. and Bondy, S.C. (1992) Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol., 5 227-231.
    • (1992) Chem. Res. Toxicol , vol.5 , pp. 227-231
    • LeBel, C.P.1    Ischiropoulos, H.2    Bondy, S.C.3
  • 41
    • 0032526238 scopus 로고    scopus 로고
    • Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes
    • Hendil, K.B., Khan, S. and Tanaka, K. (1998) Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes. Biochem. J., 332 (Pt 3), 749-754.
    • (1998) Biochem. J , vol.332 , Issue.PART 3 , pp. 749-754
    • Hendil, K.B.1    Khan, S.2    Tanaka, K.3
  • 42


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.