Laser bioeffects associated with ultrafast lasers: Role of multiphoton absorption

Journal of Laser Applications

Volumn 20, Issue 2, 2008, Pages 89-97

  Glickman, Randolph D ^a   Johnson, Thomas E ^b   Noojin, Gary D ^c   Stolarski, David J ^c   Denton, Michael L ^c   Kumar, Neeru ^a   Rockwell, Benjamin A ^d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Department of Ecosystem Science and Sustainability   (United States)

^c Northrup Grumman Warfighter and Applications Department   (United States)

^d AIR FORCE RESEARCH LABORATORY   (United States)

Author keywords

Comet assay; DNA strand breaks; Laser bioeffects; Mulitphoton absorption; RPE cell; Ultrashort pulse laser

Indexed keywords

ABSORPTION; AIR POLLUTION; ALDEHYDES; CHROMOPHORES; LASER BEAMS; LASERS; MULTIPHOTON PROCESSES; NUCLEIC ACIDS; ORGANIC ACIDS; PULSE GENERATORS; PULSED LASER DEPOSITION; ULTRASHORT PULSES;

DNA DAMAGES; ENERGY (E) THRESHOLDS; FEMTO SECONDS; LASER BIOEFFECTS; LASER EMISSIONS; LASER INDUCED BREAKDOWN (LIB); MODE-LOCKED; MULTIPHOTON ABSORPTION (MPA); NEAR INFRA-RED (NIR); RETINAL DAMAGE; RETINAL PIGMENT EPITHELIAL (RPE); SHORT WAVELENGTH (SW); ULTRA FAST LASERS; ULTRA SHORT LASER PULSES; ULTRA-SHORT PULSE LASER;

PULSED LASER APPLICATIONS;

EID: 46249113020     PISSN: 1042346X     EISSN: None     Source Type: Journal    
DOI: 10.2351/1.2900538     Document Type: Article

References (35)

1. M. Goppert-Mayer, "Über Elementarakte mit zwei Quantensprüngen," Ann. Phys. 9, 273-294 (1931).
2. W. Denk, J. H. Strickler, and W. W. Webb, "Two-photon laser scanning fluorescence microscopy," Science 248, 73-76 (1990).
3. K. Konig, P. T. So, W. W. Mantulin, B. J. Tromberg, and E. Gratton, "Two-photon excited lifetime imaging of autofluorescence in cells during UVA and NIR photostress," J. Microsc. 183, 197-204 (1996).
4. K. Konig, Y. Liu, G. J. Sonek, M. W. Berns, and B. J. Tromberg, "Autofluorescence spectroscopy of optically trapped cells," Photochem. Photobiol. 62, 830-835 (1995).
5. R. D. Glickman, B. A. Rockwell, G. D. Noojin, D. J. Stolarski, and M. L. Denton, "Evidence for excitation of fluorescence in RPE melanin by multiphoton absorption," In Laser-Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical, edited by S. L. Jacques, D. D. Duncan, S. J. Kirkpatrick, and A. Kriete, Proc. SPIE 4617, 172-179 (SPIE, Bellingham, WA, 2002).
6. R. M. Hall, R. D. Glickman, B. A. Roekwell, N. Kumar, and G. D. Noojin, "Pulse width-dependent nature of laser-induced DNA damage in RPE cells," La Laser-Tissue Interaction: Photochemical, Photothermal, and Photomechanical, edited by D. D. Duncan, S. L. Jacques, and P. C. Johnson, Proc. SPIE 4257, 159-166 (SPIE, Bellingham, WA, 2001).
7. R. D. Glickman, N. Kumar, B. A. Rockwell, G. D. Noojin, M. L. Denton, and D. J. Stolarski, "Melanin and the cellular effects of ultrashort pulse, near infrared laser radiation," In Laser-Tissue Interaction XIV, edited by S. L. Jacques, D. D. Duncan, S. J. Kirkpatrick, and A. Kriete, Proc. SPIE 4961, 97-105 (SPIE, Bellingham, WA, 2003).
8. K. Hoffmann, M. Stucker, P. Altmeyer, K. Teuchner, and D. Leupold, "Selective femtosecond pulse-excitation of melanin fluorescence in tissue," J. Invest. Dermatol. 116, 629-630 (2001).
9. K. Teuchner, W. Freyer, D. Leupold, A. Volkmer, D. J. Birch, P. Altmeyer, M. Stucker, and K. Hoffmann, "Femtosecond two-photon excited fluorescence of melanin, Photochem. Photobiol. 70, 146-151 (1999).
10. R. D. Glickman, "Phototoxicity to the retina: Mechanisms of damage," Int. J. Toxicol. 21, 473-490 (2002).
11. M. L. Denton, M. S. Foltz, L. E. Estlack, D. J. Stolarski, G. D. Noojin, R. J. Thomas, D. M. Eikum, and B. A. Rockwell, "Damage thresholds for exposure to NIR and blue lasers in an in vitro RPE cell system," Invest. Ophthalmol. Visual Sci. 47, 3065-3073 (2006).
12. X. R. Jiang, G. Jimenez, E. Chang, M. Frolkis, B. Kusler, M. Sage, M. Beeche, A. G. Bodnar, G. M. Wahl, T. D. Tlsty, and C. P. Chiu, "Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype," Nat. Genet. 21, 111-114 (1999).
13. A. G. Bodnar, M. Ouellette, M. Frolkis, S. E. Holt, C. P. Chiu, G. B. Morin, C. B. Harley, J. W. Shay, S. Lichtsteiner, and W. E. Wright, "Extension of life-span by introduction of telomerase into normal human cells," Science 279, 349-352 (1998).
14. L. Rambhatla, C.-P. Chiu, R. D. Glickman, and C. Rowe-Rendleman, "La vitro differentiation capacity of telomerase immortalized human RPE cells," Invest. Ophthalmol. Visual Sci., 43, 1622-1630 (2002).
15. C. Helma and M. Uhl, "A public domain image-analysis program for the single-cell gel-electrophoresis (comet) assay," Mutat. Res. 466, 9-15 (2000).
16. A. E. Dontsov, R. D. Glickman, and M. A. Ostrovsky, "Retinal pigment epithelium pigment granules stimulate the photo-oxidation of unsaturated fatty acids," Free Radic. Biol. Med. 26, 1436-1446 (1999).
17. G. D. Noojin, C. P. Cain, C. A. Toth, D. J. Stolarski, and B. A. Rockwell, "Comparison of retinal damage thresholds of laser pulses in the macula/paramacula regions of the live eye," La Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, edited by S. L. Jacques, G. J. Müller, A. Roggan, and D. H. Sliney, Proc. SPIE 3601, 39-42 (SPIE, Bellingham, WA, 1999).
18. R. J. Thomas, G. D. Noojin, D. J. Stolarski, R. T. Hall, C. P. Cain, C. A. Toth, MD, and B. A. Rockwell, "A comparative study of retinal effects from continuous wave and femtosecond mode-locked lasers," Lasers Surg. Med. 31, 9-17 (2002).
19. R. D. Glickman, M. Natarajan, B. A. Rockwell, M. Denton, S. Maswadi, N. Kumar, and F. Nieves-Roldan, "Intracellular signaling mechanisms responsive to laser-induced photochemical and thermal stress," In Optical Interactions with Tissues and Cells XVI, edited by S. L. Jacques, and W. P. Roach, Proc. SPIE 5695, 260-269 (SPIE, Bellingham, WA, 2005).
20. H. Cember, Introduction to Health Physics (McGraw-Hill, New York, 1996).
21. R. D. Glickman, J. M. Gallas, S. L. Jacques, B. A. Rockwell, and D. K. Sardar, "Physical and photochemical properties of ocular melanin," In Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, edited by V. V. Tuchin, Proc. SPIE 4241, 112-123 (SPIE, Bellingham, WA, 2001).
22. R. D. Glickman, "The origin of photo-oxidative stress in the aging eye," Prog. Brain Res. 131, 699-712 (2001).
23. D. K. Sardar, M. L. Mayo, and R. D. Glickman, "Optical characterization of melanin," J. Biomed. Opt. 6, 404-411 (2001).
24. C. P. Cain, C. A. Toth, G. D. Noojin, V. Carothers, D. J. Stolarski, and B. A. Rockwell, "Thresholds for visible lesions in the primate eye produced by ultrashort near-infrared laser pulses," Invest. Ophthalmol. Visual Sci. 40, 2343-2349 (1999).
25. R. J. Thomas, G. D. Noojin, P. K. Kennedy, B. A. Rockwell, K. S. Denning, J. Shaver, and G. D. Buffington, "Laser damage threshold trends for sub-100 fs pulses in the retina," In Laser-Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical, edited by S. L. Jacques, D. D. Duncan, S. J. Kirkpatrick, and A. Kriete, Proc. SPIE 4617, 141-149 (SPIE, Bellingham, WA, 2002).
26. M. L. Denton, D. M. Eikum, D. J. Stolarski, G. D. Noojin, R. J. Thomas, R. D. Glickman, and B. A. Rockwell, "Hydrogen peroxide production in cultured RPE cells exposed to near infrared lasers," In Laser Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical, edited by S. L. Jacques, D. D. Duncan, S. J. and Kirkpatrick, A. Kriete, Proc. SPIE 4617, 150-155 (SPIE, Bellingham, WA, 2002).
27. M. L. Denton, D. M. Eikum, D. J. Stolarski, G. D. Noojin, R. D. Thomas, R. D. Glickman, and B. A. Rockwell, "Cytotoxicity in cultured RPE: A comparative study between continuous wave and mode-locked lasers," In Laser-Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical, edited by S. L. Jacques, D. D. Duncan, S. J. Kirkpatrick, and A. Kriete, Proc SPIE 4617, 156-160 (SPIE, Bellingham, WA, 2002).
28. P. A. Riley, "Radicals in melanin biochemistry," Ann. N.Y. Acad. Sci. 551, 111-120 (1988).
29. P. K. Kennedy, S. A. Boppart, D. X. Hammer, B. A. Rockwell, G. D. Noojin, and W. P. Roach, "A first-order model for computation of laser-induced breakdown thresholds in ocular and aqueous media: Part II-comparison to experiment," IEEE J. Quantum Electron. QE-31, 2250-2257 (1995).
30. C. P. Cain, C. D. DiCarlo, B. A. Rockwell, P. K. Kennedy, G. D. Noojin, D. J. Stolarski, D. X. Hammer, C. A. Toth, and W. P. Roach, "Retinal damage and laser-induced breakdown produced by ultrashort-pulse lasers," Graefe's Arch. Clin. Exp. Ophthalmol. 234 Suppl. 1, S28-S37 (1996).
31. B. A. Rockwell, D. X. Hammer, R. A. Hopkins, D. J. Payne, C. A. Toth, W. P. Roach, J. J. Druessel, P. K. Kennedy, R. E. Amnotte, B. Eilert, S. Phillips, G. D. Noojin, D. J. Stolarski, and C. Cain, "Ultrashort laser pulse bioeffects and safety," J. Laser Appl. 11, 42-44 (1999).
32. T. Sarna, "Properties and function of the ocular melanin - A photobiophysical view," J. Photochem. Photobiol., B 12, 215-258 (1992).
33. W. T. Ham Jr., R. G. Allen, L. Feeney-Burns, M. F. Marmor, L. M. Parver, P. H. Proctor, D. H. Sliney, and M. L. Wolbarsht, "The involvement of the retinal pigment epithelium (RPE)," in Optical Radiation and Visual Health, edited by M. Waxler and V. M. Hitchins (CRC, Boca Raton, FL, 1986), pp. 43-67.
34. C. R. Thompson, B. S. Gerstman, S. L. Jacques, and M. E. Rogers, "Melanin granule model for laser-induced thermal damage in the retina," Bull. Math. Biol. 58, 513-553 (1996).
35. S. H. Leuba, C. Bustamante, J. Zlatanova, and K. van Holde, "Contributions of linker histones and histone H3 to chromatin structure: Scanning force microscopy studies on trypsinized fibers," Biophys. J. 74, 2823-2829 (1998).