-
1
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, Muhammad Tunio G, Matsuzawa Y, Kanakura Y, Shinomura Y, Kitamura Y: Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998;279:577-580.
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
Muhammad Tunio, G.11
Matsuzawa, Y.12
Kanakura, Y.13
Shinomura, Y.14
Kitamura, Y.15
-
2
-
-
0031791026
-
A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumors
-
Nakahara M, Isozaki K, Hirota S, Miyagawa J, Hase-Sawada N, Taniguchi M, Nishida T, Kanayama S, Kitamura Y, Shinomura Y, Matsuzawa Y: A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumors. Gastroenterology 1998;115:1090-1095.
-
(1998)
Gastroenterology
, vol.115
, pp. 1090-1095
-
-
Nakahara, M.1
Isozaki, K.2
Hirota, S.3
Miyagawa, J.4
Hase-Sawada, N.5
Taniguchi, M.6
Nishida, T.7
Kanayama, S.8
Kitamura, Y.9
Shinomura, Y.10
Matsuzawa, Y.11
-
3
-
-
0035890740
-
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors
-
Rubin BP, Singer S, Tsao C, Duensing A, Lux ML, Ruiz R, Hibbard MK, Chen CJ, Xiao S, Tuveson DA, Demetri GD, Fletcher CD, Fletcher JA: KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res 2001;61:8118-8121.
-
(2001)
Cancer Res
, vol.61
, pp. 8118-8121
-
-
Rubin, B.P.1
Singer, S.2
Tsao, C.3
Duensing, A.4
Lux, M.L.5
Ruiz, R.6
Hibbard, M.K.7
Chen, C.J.8
Xiao, S.9
Tuveson, D.A.10
Demetri, G.D.11
Fletcher, C.D.12
Fletcher, J.A.13
-
4
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
Heinrich MC, Corless CL, Duensing A, McGreevey L, Chen CJ, Joseph N, Singer S, Griffith DJ, Haley A, Town A, Demetri GD, Fletcher CD, Fletcher JA: PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003;229:708-710.
-
(2003)
Science
, vol.229
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
McGreevey, L.4
Chen, C.J.5
Joseph, N.6
Singer, S.7
Griffith, D.J.8
Haley, A.9
Town, A.10
Demetri, G.D.11
Fletcher, C.D.12
Fletcher, J.A.13
-
5
-
-
23944476156
-
PDGFRA mutations in gastrointestinal stromal tumors: Frequency, spectrum and in vitro sensitivity to imatinib
-
Corless CL, Schroeder A, Griffith D, Town A, McGreevey L, Harrell P, Shiraga S, Bainbridge T, Morich J, Heinrich MC: PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib. J Clin Oncol 2005;23:5357-5364.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5357-5364
-
-
Corless, C.L.1
Schroeder, A.2
Griffith, D.3
Town, A.4
McGreevey, L.5
Harrell, P.6
Shiraga, S.7
Bainbridge, T.8
Morich, J.9
Heinrich, M.C.10
-
6
-
-
5444222014
-
Myxoid epithelioid gastrointestinal stromal tumor (GIST) with mast cell infiltrations: A subtype of GIST with mutations of platelet-derived growth factor receptor alpha gene
-
Sakurai S, Hasegawa T, Sakuma Y, Takazawa Y, Motegi A, Nakajima T, Saito K, Fukayama M, Shimoda T: Myxoid epithelioid gastrointestinal stromal tumor (GIST) with mast cell infiltrations: a subtype of GIST with mutations of platelet-derived growth factor receptor alpha gene. Hum Pathol 2004;35:1223-1230.
-
(2004)
Hum Pathol
, vol.35
, pp. 1223-1230
-
-
Sakurai, S.1
Hasegawa, T.2
Sakuma, Y.3
Takazawa, Y.4
Motegi, A.5
Nakajima, T.6
Saito, K.7
Fukayama, M.8
Shimoda, T.9
-
7
-
-
1842426806
-
Gastrointestinal stromal tumors (GISTs) negative for KIT (CD117 antigen) immunoreactivity
-
Debiec-Rychter M, Wasag B, Stul M, De Wever I, Van Oosterom A, Hagemeijer A, Sciot R: Gastrointestinal stromal tumors (GISTs) negative for KIT (CD117 antigen) immunoreactivity. J Pathol 2004;202:430-438.
-
(2004)
J Pathol
, vol.202
, pp. 430-438
-
-
Debiec-Rychter, M.1
Wasag, B.2
Stul, M.3
De Wever, I.4
Van Oosterom, A.5
Hagemeijer, A.6
Sciot, R.7
-
8
-
-
0026551550
-
Genomic organization of the human c-kit gene: Evolution of the receptor tyrosine kinase subclass III
-
Andre C, Martin E, Cornu F, Hu WX, Wang XP, Galibert F: Genomic organization of the human c-kit gene: evolution of the receptor tyrosine kinase subclass III. Oncogene 1992;7:685-691.
-
(1992)
Oncogene
, vol.7
, pp. 685-691
-
-
Andre, C.1
Martin, E.2
Cornu, F.3
Hu, W.X.4
Wang, X.P.5
Galibert, F.6
-
9
-
-
0028001294
-
A YAC contig spanning a cluster of human type III receptor protein tyrosine kinase genes (PDGFRA-KIT-KDR) in chromosome segment 4p12
-
Spritz RA, Strunk KM, Lee ST, Lu-Kuo JM, Ward DC, Le Paslier D, Altherr MR, Dorman TE, Moir DT: A YAC contig spanning a cluster of human type III receptor protein tyrosine kinase genes (PDGFRA-KIT-KDR) in chromosome segment 4p12. Genomics 1994;22:431-436.
-
(1994)
Genomics
, vol.22
, pp. 431-436
-
-
Spritz, R.A.1
Strunk, K.M.2
Lee, S.T.3
Lu-Kuo, J.M.4
Ward, D.C.5
Le Paslier, D.6
Altherr, M.R.7
Dorman, T.E.8
Moir, D.T.9
-
10
-
-
0023989811
-
Primary structure of c-kit: Relationship with the CSF-1/PDGF receptor kinase family - oncogenic activation of v-kit involves deletion of extracellular domain and C terminus
-
Qiu FH, Ray P, Brown K, Barker PE, Jhanwar S, Ruddle FH, Besmer P: Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family - oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J 1988;7:1003-1011.
-
(1988)
EMBO J
, vol.7
, pp. 1003-1011
-
-
Qiu, F.H.1
Ray, P.2
Brown, K.3
Barker, P.E.4
Jhanwar, S.5
Ruddle, F.H.6
Besmer, P.7
-
11
-
-
0036301722
-
Diagnosis of gastrointestinal stromal tumors: A consensus approach
-
Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, Miettinen M, O'Leary TJ, Remotti H, Rubin BP, Shmookler B, Sobin LH, Weiss SW: Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 2002;33:459-465.
-
(2002)
Hum Pathol
, vol.33
, pp. 459-465
-
-
Fletcher, C.D.1
Berman, J.J.2
Corless, C.3
Gorstein, F.4
Lasota, J.5
Longley, B.J.6
Miettinen, M.7
O'Leary, T.J.8
Remotti, H.9
Rubin, B.P.10
Shmookler, B.11
Sobin, L.H.12
Weiss, S.W.13
-
12
-
-
2442551759
-
Prognostic significance of c-kit mutation in localized gastrointestinal stromal tumors
-
Kim TW, Lee H, Kang YK, Choe MS, Ryu MH, Chang HM, Kim JS, Yook JH, Kim BS, Lee JS: Prognostic significance of c-kit mutation in localized gastrointestinal stromal tumors. Clin Cancer Res 2004;10:3076-3081.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3076-3081
-
-
Kim, T.W.1
Lee, H.2
Kang, Y.K.3
Choe, M.S.4
Ryu, M.H.5
Chang, H.M.6
Kim, J.S.7
Yook, J.H.8
Kim, B.S.9
Lee, J.S.10
-
13
-
-
0642368571
-
Kinase mutations and imatinib response in patients with metastatic gastrointestinal tumor
-
Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, McGreevey LS, Chen CJ, Van den Abbeele AD, Druker BJ, Kiese B, Eisenberg B, Roberts PJ, Singer S, Fletcher CD, Silberman S, Dimitrijevic S, Fletcher JA: Kinase mutations and imatinib response in patients with metastatic gastrointestinal tumor. J Clin Oncol 2003;21:4342-4349.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4342-4349
-
-
Heinrich, M.C.1
Corless, C.L.2
Demetri, G.D.3
Blanke, C.D.4
von Mehren, M.5
Joensuu, H.6
McGreevey, L.S.7
Chen, C.J.8
Van den Abbeele, A.D.9
Druker, B.J.10
Kiese, B.11
Eisenberg, B.12
Roberts, P.J.13
Singer, S.14
Fletcher, C.D.15
Silberman, S.16
Dimitrijevic, S.17
Fletcher, J.A.18
-
14
-
-
3042646931
-
A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential
-
Lasota J, Dansonka-Mieszkowska A, Sobin LH, Miettinen M: A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential. Lab Invest 2004;84:874-883.
-
(2004)
Lab Invest
, vol.84
, pp. 874-883
-
-
Lasota, J.1
Dansonka-Mieszkowska, A.2
Sobin, L.H.3
Miettinen, M.4
-
15
-
-
2142747025
-
KIT-negative gastrointestinal stromal tumors: Proof of concept and therapeutic implications
-
Medeiros F, Corless CL, Duensing A, Hornick JL, Oliveira AM, Heinrich MC, Fletcher JA, Fletcher CD: KIT-negative gastrointestinal stromal tumors: proof of concept and therapeutic implications. Am J Surg Pathol 2004;28:889-894.
-
(2004)
Am J Surg Pathol
, vol.28
, pp. 889-894
-
-
Medeiros, F.1
Corless, C.L.2
Duensing, A.3
Hornick, J.L.4
Oliveira, A.M.5
Heinrich, M.C.6
Fletcher, J.A.7
Fletcher, C.D.8
-
16
-
-
3342991696
-
Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site
-
Wasag B, Debiec-Rychter M, Pauwels P, Stul M, Vranckx H, Oosterom AV, Hagemeijer A, Sciot R: Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site. Mod Pathol 2004;17:889-894.
-
(2004)
Mod Pathol
, vol.17
, pp. 889-894
-
-
Wasag, B.1
Debiec-Rychter, M.2
Pauwels, P.3
Stul, M.4
Vranckx, H.5
Oosterom, A.V.6
Hagemeijer, A.7
Sciot, R.8
-
17
-
-
4344611744
-
Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors
-
Wardelmann E, Hrychyk A, Merkelbach-Bruse S, Pauls K, Goldstein J, Hohenberger P, Losen I, Manegold C, Buttner R, Pietsch T: Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors. J Mol Diagn 2004;6:197-204.
-
(2004)
J Mol Diagn
, vol.6
, pp. 197-204
-
-
Wardelmann, E.1
Hrychyk, A.2
Merkelbach-Bruse, S.3
Pauls, K.4
Goldstein, J.5
Hohenberger, P.6
Losen, I.7
Manegold, C.8
Buttner, R.9
Pietsch, T.10
-
18
-
-
20944446788
-
PDGFR expression in differential diagnosis between KIT-negative gastrointestinal stromal tumors and other primary soft-fissue tumors of the gastrointestinal tract
-
Rossi G, Valli R, Bertolini F, Marchioni A, Cavazza A, Mucciarini C, Migaldi M, Federico M, Trentini GP, Sgambato A: PDGFR expression in differential diagnosis between KIT-negative gastrointestinal stromal tumors and other primary soft-fissue tumors of the gastrointestinal tract. Histopathology 2005;46:522-531.
-
(2005)
Histopathology
, vol.46
, pp. 522-531
-
-
Rossi, G.1
Valli, R.2
Bertolini, F.3
Marchioni, A.4
Cavazza, A.5
Mucciarini, C.6
Migaldi, M.7
Federico, M.8
Trentini, G.P.9
Sgambato, A.10
-
19
-
-
14344256167
-
PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features
-
Pauls K, Merkelbach-Bruse S, Thal D, Buttner R, Wardelmann E: PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features. Histopathology 2005;46:166-175.
-
(2005)
Histopathology
, vol.46
, pp. 166-175
-
-
Pauls, K.1
Merkelbach-Bruse, S.2
Thal, D.3
Buttner, R.4
Wardelmann, E.5
-
20
-
-
0041971080
-
Gain-of-function of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors
-
Hirota S, Ohashi A, Nishida T, Isozaki K, Kinoshita K, Shinomura Y, Kitamura Y: Gain-of-function of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors. Gastroenterology 2003;125:660-667.
-
(2003)
Gastroenterology
, vol.125
, pp. 660-667
-
-
Hirota, S.1
Ohashi, A.2
Nishida, T.3
Isozaki, K.4
Kinoshita, K.5
Shinomura, Y.6
Kitamura, Y.7
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