Development of a microperfusion system for the culture of bioengineered heart muscle

ASAIO Journal

Volumn 54, Issue 3, 2008, Pages 284-294

  Hecker, Louise ^a   Khait, Luda ^a   Radnoti, Desmond ^a,b   Birla, Ravi ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Radnoti Glass Technology Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC TISSUE ENGINEERING; FIBRIN GELS; FLUID DELIVERY; HEART MUSCLES; IN-VITRO; MICROPERFUSION; MITOCHONDRIAL ACTIVITY; PERFUSION SYSTEM; SUPPORT MATRIX; TISSUE CONSTRUCTS; TISSUE CULTURE PLATES; TOTAL PROTEIN;

GELATION; MODELS; NUCLEIC ACIDS; OXYGENATION; RNA; THREE DIMENSIONAL; TISSUE CULTURE; TISSUE ENGINEERING;

MUSCLE;

FIBRIN; MUSCLE PROTEIN; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASPIRATION; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; FLOW RATE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART PACING; IN VITRO STUDY; MUSCLE FIBER CULTURE; MUSCLE TWITCH; NONHUMAN; NUTRIENT SUPPLY; OXYGENATION; PERFUSION; PH; RAT; THERMOREGULATION; TISSUE ENGINEERING; ANIMAL; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; EQUIPMENT DESIGN; EVALUATION; GEL; HEART CONTRACTION; INSTRUMENTATION; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA; EQUIPMENT DESIGN; FIBRIN; GELS; MUSCLE PROTEINS; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PERFUSION; RATS; RNA; TISSUE ENGINEERING;

EID: 46249095575     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAT.0b013e31817432dc     Document Type: Article

References (25)

1. Hecker L, Birla R: Engineering the heart piece by piece: state of the art in cardiac tissue engineering. Regen Med2: 125-144, 2007.
2. Khait L, Birla RK: Cell based cardiac pumps and tissue engineered ventricles. Regen Med2: 1-17, 2007.
3. Baar K, Birla R, Boluyt MO, et al: Self-organization of rat cardiac cells into contractile 3-D cardiac tissue. FASEB J2: 275-277,2005.
4. Huang YC, Khait L, Birla RK: Contractile three-dimensional bioengineered heart muscle for myocardial regeneration. J Biomed Mat Res80: 719-731, 2007.
5. Blan N, Birla RK: Design and fabrication of heart muscle using scaffold based tissue engineering. J Biomed Mat Res2007 [Epub ahead of print].
6. Colton CK: Implantable biohybrid artificial organs. Cell Transplant4: 415-436, 1995.
7. Henry TD: Therapeutic angiogenesis. BMJ318: 1536-1539,1999.
8. Hockel M, Schlenger K, Doctrow S, et al: Therapeutic angiogenesis. Arch Surg128: 423-429, 1993.
9. ÓToole G, MacKenzie D, Buckley MF, et al: A review of therapeutic angiogenesis and consideration of its potential applications to plastic and reconstructive surgery. Br J Plastic Surg54: 1-7, 2001.
10. Sellke FW, Simons M: Angiogenesis in cardiovascular disease current status and therapeutic potential. Drugs58: 391-396, 1999.
11. Soker S, Machado M, Atala A: Systems for therapeutic angiogenesis in tissue engineering. World J Urol18: 10-18, 2000.
12. Bilodeau K, Mantovani D: Bioreactors for tissue engineering: focus on mechanical constraints. A comparative review. Tissue Eng12: 2367-2383, 2006.
13. Chen HC, Hu YC: Bioreactors for tissue engineering. Biotech Lett28: 1415-1423, 2006.
14. Martin I, Wendt D, Heberer M: The role of bioreactors in tissue engineering. Trends Biotech22: 80-86, 2004.
15. Portner R, Nagel-Heyer S, Goepfert C, et al: Bioreactor design for tissue engineering. J Biosci Bioeng100: 235-245, 2005.
16. Ratcliffe A, Niklason LE: Bioreactors and bioprocessing for tissue engineering. Ann NY Acad Sci961: 210-215, 2002.
17. Carrier RL, Papadaki M, Rupnick M, et al: Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization. Biotech Bioeng64: 580-589, 1999.
18. Carrier RL, Rupnick M, Langer R, et al: Perfusion improves tissue architecture of engineered cardiac muscle. Tissue Eng8: 175-188, 2002.
19. Carrier RL, Rupnick M, Langer R, et al: Effects of oxygen on engineered cardiac muscle. Biotech Bioeng78: 617-625,2002.
20. Birla RK, Huang YC, Dennis RG: Development of a novel bioreactor for the mechanical loading of tissue-engineered heart muscle. Tissue Eng13: 2239-2248, 2007.
21. Boluyt MO, Zheng JS, Younes A, et al: Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70 S6 kinase. Circ Res81: 176-186, 1997.
22. Dennis RG, Kosnik PE: Excitability and isometric contractile properties of mammalian skeletal muscle constructs engineered in vitro. In Vitro Cell Dev Biol Anim36: 327-335, 2000.
23. Dennis RG, Kosnik PE, Gilbert ME, et al: Excitability and contractility of skeletal muscle engineered from primary cultures and cell lines. Am J Physiol Cell Physiol280: C288-C295, 2001.
24. Birla RK, Borschel GH, Dennis RG, et al: Myocardial engineering in vivo: formation and characterization of contractile, vascularized three-dimensional cardiac tissue. Tissue Eng11: 803-813, 2005.
25. Birla RK, Borschel GH, Dennis RG: In vivo conditioning of tissueengineered heart muscle improves contractile performance. Artif Organs29: 866-875, 2005.