메뉴 건너뛰기




Volumn 4, Issue 3, 2008, Pages 301-303

IL-12 and IL-23 in health and disease

Author keywords

[No Author keywords available]

Indexed keywords

ABT 874; ANTIINFLAMMATORY AGENT; CNTO 1275; CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 23; MESSENGER RNA; STA 5326;

EID: 46149125283     PISSN: 1744666X     EISSN: None     Source Type: Journal    
DOI: 10.1586/1744666X.4.3.301     Document Type: Editorial
Times cited : (2)

References (15)
  • 1
    • 33846197859 scopus 로고    scopus 로고
    • The interleukin-12 family: New players in transplantation immunity?
    • Goriely S, Goldman M. The interleukin-12 family: new players in transplantation immunity? Am. J. Transplant. 7, 278-284 (2007).
    • (2007) Am. J. Transplant , vol.7 , pp. 278-284
    • Goriely, S.1    Goldman, M.2
  • 2
    • 28844465015 scopus 로고    scopus 로고
    • IL-23: Changing the verdict on IL-12 function in inflammation and autoimmunity
    • Kreymborg K, Bohlmann U, Becher B. IL-23: changing the verdict on IL-12 function in inflammation and autoimmunity. Expert Opin. Ther. Targets 9(60), 1123-1136 (2005).
    • (2005) Expert Opin. Ther. Targets , vol.9 , Issue.60 , pp. 1123-1136
    • Kreymborg, K.1    Bohlmann, U.2    Becher, B.3
  • 3
    • 0346962972 scopus 로고    scopus 로고
    • Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
    • Murphy CA, Langrish CL, Chen Y et al. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. Exp. Med. 198(12), 1951-1957 (2003).
    • (2003) J. Exp. Med , vol.198 , Issue.12 , pp. 1951-1957
    • Murphy, C.A.1    Langrish, C.L.2    Chen, Y.3
  • 4
    • 34948840330 scopus 로고    scopus 로고
    • The IL23 axis plays a key role in the pathogenesis of IBD
    • McGovern D, Powrie E The IL23 axis plays a key role in the pathogenesis of IBD. Gut 56, 1333-1336 (2007).
    • (2007) Gut , vol.56 , pp. 1333-1336
    • McGovern, D.1    Powrie, E.2
  • 5
    • 21844444831 scopus 로고    scopus 로고
    • IL-12 family members: IL-23 and IL-27, cytokines with divergent functions
    • Hunter C. New IL-12 family members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol. 5, 521-531 (2005).
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 521-531
    • New, H.C.1
  • 9
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3(2), 133-146 (2003).
    • (2003) Nat. Rev. Immunol , vol.3 , Issue.2 , pp. 133-146
    • Trinchieri, G.1
  • 10
    • 0345358584 scopus 로고    scopus 로고
    • new players in the regulation of T cell responses
    • The IL-12 family of heterodimeric cytokines
    • Trinchieri G, Pflanz S, Kastelein RA, The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity (19), 641-644 (2003).
    • (2003) Immunity , vol.19 , pp. 641-644
    • Trinchieri, G.1    Pflanz, S.2    Kastelein, R.A.3
  • 12
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201(2), 233-240 (2005).
    • (2005) J. Exp. Med , vol.201 , Issue.2 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 13
    • 8344284998 scopus 로고    scopus 로고
    • Anti-interleukin 12 antibody for active Crohn's disease
    • Mannon PJ, Fuss IJ, Mayer L et al. Anti-interleukin 12 antibody for active Crohn's disease. N. Engl. J. Med. 351(20), 2069-2079 (2004).
    • (2004) N. Engl. J. Med , vol.351 , Issue.20 , pp. 2069-2079
    • Mannon, P.J.1    Fuss, I.J.2    Mayer, L.3
  • 14
    • 39649108216 scopus 로고    scopus 로고
    • Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis results of a randomized, placebo-controlled, Phase 2 trial
    • Kimball AB, Gordon KB, Langley RG, Menter A, Chartash EK, Valdes J. Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis results of a randomized, placebo-controlled, Phase 2 trial. Arch. Dermatol. 144(2), 200-207 (2008).
    • (2008) Arch. Dermatol , vol.144 , Issue.2 , pp. 200-207
    • Kimball, A.B.1    Gordon, K.B.2    Langley, R.G.3    Menter, A.4    Chartash, E.K.5    Valdes, J.6
  • 15
    • 33846889522 scopus 로고    scopus 로고
    • Krueger GG, Langley RG, Leonardi C et al. A human interleukin-12/ 23 monoclonal antibody for psoriasis. N. Engl. J. Med. (356)6, 580-592 (2008).
    • Krueger GG, Langley RG, Leonardi C et al. A human interleukin-12/ 23 monoclonal antibody for psoriasis. N. Engl. J. Med. (356)6, 580-592 (2008).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.