Short synthesis of the selective rho-kinase inhibitor Y-27632 and of its enantiomer

Letters in Organic Chemistry

Volumn 2, Issue 7, 2005, Pages 634-636

  Belotti, Damien ^a   Peglion, Jean Louis ^b   Cossy, Janine ^a  

^a CNRS   (France)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Kinase inhibitor; Reductive amination; Rho associated kinase; Y 27632

Indexed keywords

EID: 46149116599     PISSN: 15701786     EISSN: None     Source Type: Journal    
DOI: 10.2174/157017805774297019     Document Type: Review

References (24)

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21. Determined by GC/MS. The diastereoselectivity of 95/5 is the same for both trans- and cis-isomers.
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