Characterization of replication fork and phosphorylation stimulated Plasmodium falciparum helicase 45

Gene

Volumn 420, Issue 1, 2008, Pages 66-75

  Pradhan, Arun ^a,b   Hussain, Ejaz M ^b   Tuteja, Renu ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

Author keywords

DEAD box protein; Plasmodium falciparum; ssDNA dependent ATPase; Translation initiation factor; Unwinding enzyme

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ADENOSINE TRIPHOSPHATASE; CONGOCIDINE; DACTINOMYCIN; DAUNORUBICIN; ETHIDIUM BROMIDE; HELICASE; NOGALAMYCIN; NUCLEIC ACID; PLASMODIUM FALCIPARUM HELICASE 45; PROTEIN KINASE C; RNA; RNA HELICASE; SERINE;

ARTICLE; DNA BINDING; ENZYME ACTIVITY; GENE REPLICATION; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADENOSINE TRIPHOSPHATASES; ANIMALS; DNA HELICASES; DNA REPLICATION; NUCLEIC ACID CONFORMATION; PHOSPHORYLATION; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RNA-BINDING PROTEINS;

PLASMODIUM FALCIPARUM;

EID: 46149086732     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2008.05.005     Document Type: Article

References (51)

1. Bachur N.R., et al. Anthracycline antibiotic blockade of SV40 T antigen helicase action. Biochem. Pharmacol. 55 (1998) 1025-1034
2. Bachur N.R., Yu F., Johnson R., Hickey R., Wu Y., and Malkas L. Helicase inhibition by anthracycline anticancer agents. Mol. Pharmacol. 41 (1992) 993-998
3. Bahl A., et al. PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res. 31 (2003) 212-215
4. Blom N., Sicheritz-Ponten T., Gupta R., Gammeltoft S., and Brunak S. Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics 4 (2004) 1633-1649
5. Borowski P., et al. NTPase/helicase of Flaviviridae: inhibitors and inhibition of the enzyme. Acta Biochimica Polonica 49 (2002) 597-614
6. Brosh Jr. R.M., Karow J.K., White E.J., Shaw N.D., Hickson I.D., and Bohr V.A. Potent inhibition of Werner and Bloom helicases by DNA minor groove binding drugs. Nucleic Acids Res. 28 (2000) 2420-2430
7. Buelt M.K., Glidden B.J., and Storm D.R. Regulation of p68 RNA helicase by calmodulin and protein kinase C. J. Biol. Chem. 269 (1994) 29367-29370
8. Cheng Z., Coller J., Parker R., and Song H. Crystal structure and functional analysis of DEAD-box protein Dhh1p. RNA 11 (2005) 1258-1270
9. Du M.X., Johnson R.B., Sun X.L., Staschke K.A., Colacino J., and Wang Q.M. Comparative characterization of two DEAD-box RNA helicases in superfamily II: human translation-initiation factor 4A and hepatitis C virus non-structural protein 3 (NS3) helicase. Biochem. J. 363 (2002) 147-155
10. Frick D.N., and Lam A.M. Understanding helicases as a means of virus control. Curr. Pharm. Des. 12 (2006) 1315-1338
11. Gardner M.J., et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419 (2002) 498-511
12. George J.W., Ghate S., Matson S.W., and Besterma J.M. Inhibition of DNA helicase II unwinding and ATPase activities by DNA-interacting ligands. Kinetics and specificity. J. Biol. Chem. 267 (1992) 10683-10689
13. Gorbalenya A.E., Koonin E.V., Donchenko A.P., and Blinov V.M. Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res. 17 (1989) 4713-4730
14. Hall M.C., and Matson S.W. Helicase motifs: the engine that powers DNA unwinding. Mol. Microbiol. 34 (1999) 867-877
15. Hernandez G., and Vazquez-Pianzola P. Functional diversity of the eukaryotic translation initiation factors belonging to eIF4 families. Mech. Dev. 122 (2005) 865-876
16. Hunter T., and Sefton B.M. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc. Natl. Acad. Sci. USA 77 (1980) 1311-1315
17. Hyde J.E. Drug-resistant malaria: an insight. FEBS J. 274 (2007) 4688-4698
18. Kim O.T.P., Yura K., and Go N. Amino acid residue doublet propensity in the protein-RNA interface and its application to RNA interface prediction. Nucleic Acids Res. 34 (2006) 6450-6460
19. Kumar A., Vaid A., Syin C., and Sharma P. PfPKB, a novel protein kinase B-like enzyme from Plasmodium falciparum. I. Identification, characterization, and possible role in parasite development. J. Biol. Chem. 27 (2004) 24255-24264
20. Linder P. DEAD-box proteins: a family affair-active and passive players in RNP-remodeling. Nucleic Acids Res. 34 (2006) 4168-4180
21. Linder P., et al. Birth of the D-E-A-D box. Nature 337 (1989) 121-122
22. Luking A., Stahl U., and Schmidt U. The protein family of RNA helicases. Crit. Rev. Biochem. Mol. Biol. 33 (1998) 259-296
23. Matson S.W., Bean D., and George J.W. DNA helicases; enzymes with essential roles in all aspects of DNA metabolism. BioEssays 16 (1994) 13-21
24. Nasirudin K.M., Ehtesham N.Z., Tuteja R., Sopory S.K., and Tuteja N. The Gly-Arg-rich C-terminal domain of pea nucleolin is a DNA helicase that catalytically translocates in the 5′-to 3′-direction. Arch. Biochem. Biophysics 434 (2005) 306-315
25. Pause A., and Sonenberg N. Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A. EMBO J. 11 (1992) 2643-2654
26. Pham X.H., Reddy M.K., Ehtesham N.Z., Matta B., and Tuteja N. A DNA helicase from Pisum sativum is homologous to translation initiation factor and stimulates topoisomerase activity. Plant J. 24 (2000) 219-229
27. Pham X.H., and Tuteja N. Potent inhibition of DNA unwinding and ATPase activities of pea DNA helicase 45 by DNA-binding agents. Biochem. Biophys. Res. Comm. 294 (2002) 334-339
28. Phan T.N., Ehtesham N.Z., Tuteja R., and Tuteja N. A novel nuclear DNA helicase with high specific activity from Pisum sativum catalytically translocates in the 3′-5′ direction. Eur. J. Biochem. 270 (2003) 1735-1745
29. Pradhan A., Chauhan V.S., and Tuteja R. Plasmodium falciparum DNA helicase 60 is a schizont stage specific, bipolar and dual helicase stimulated by PKC phosphorylation. Mol. Biochem. Parasitol. 144 (2005) 133-141
30. Pradhan A., and Tuteja R. Plasmodium falciparum DNA helicase 60: dsRNA-and antibody-mediated inhibition of the malaria parasite growth and down regulation of its enzyme activities by DNA-interacting compounds. FEBS J. 273 (2006) 3545-3556
31. Pradhan A., and Tuteja R. Bipolar, dual Plasmodium falciparum helicase 45 expressed during intraerythrocytic developmental cycle is required for parasite growth. J. Mol. Biol. 373 (2007) 268-281
32. Rocak S., and Linder P. DEAD-box proteins: the driving forces behind RNA metabolism. Nat. Rev. Mol. Cell Biol. 5 (2004) 232-241
33. Rogers G.W., Lima W.F., and Merrick W.C. Further characterization of the helicase activity of eIF4A: substrate specificity. J. Biol. Chem. 276 (2001) 12598-12608
34. Sambrook J., Fritsch E., and Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd ed (1989), Cold Spring Harbor Laboratory Press, Cold Spring Harbor
35. Seo Y.-S., and Hurwitz J. Isolation of helicase alpha, a DNA helicase from HeLa cells stimulated by a fork structure and single-stranded DNA-binding proteins. J. Biol. Chem. 268 (1993) 10282-10295
36. Tuteja N., Beven A.F., Shaw P.J., and Tuteja R. A pea homologue of human DNA helicase I is localized within the dense fibrillar component of the nucleolus and stimulated by phosphorylation with CK2 and cdc2 protein kinases. Plant J. 25 (2001) 9-17
37. Tuteja N., et al. Human DNA helicase IV is nucleolin, an RNA helicase modulated by phosphorylation. Gene 160 (1995) 143-148
38. Tuteja N., and Phan T.-N. Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands. Biochem. Biophys. Res. Comm. 244 (1998) 861-867
39. Tuteja N., Phan T.N., Tuteja R., Ochem A., and Falaschi A. Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents. Biochem. Biophys. Res. Comm. 236 (1997) 636-640
40. Tuteja N., and Tuteja R. Prokaryotic and eukaryotic DNA helicases. Essential molecular motor proteins for cellular machinery. Eur. J. Biochem. 271 (2004) 1835-1848
41. Tuteja N., and Tuteja R. Unraveling DNA helicases. Motif, structure, mechanism and function. Eur. J. Biochem. 271 (2004) 1849-1863
42. Tuteja N., and Tuteja R. Helicases as molecular motors: an insight. Physica Acta 372 (2006) 70-83
43. Tuteja N., Tuteja R., Ochem A., Taneja P., Huang N.W., et al. Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen. EMBO J. 13 (1994) 4991-5001
44. Tuteja R. Malaria-an overview. FEBS J. 274 (2007) 4670-4679
45. Tuteja R. Helicases: feasible anti-malarial drug target for Plasmodium falciparum. FEBS J. 274 (2007) 4699-4704
46. Tuteja R., and Pradhan A. Unraveling the 'DEAD-box' helicases of Plasmodium falciparum. Gene 376 (2006) 1-12
47. Tuteja R., Tuteja N., Malhotra P., and Chauhan V.S. Replication fork stimulated eIF-4A from Plasmodium cynomolgi unwinds DNA in the 3′ to 5′ direction and is inhibited by DNA-interacting compounds. Arch. Biochem. Biophysics 414 (2003) 108-114
48. Vashisht A.A., Pradhan A., Tuteja R., and Tuteja N. Cold-and salinity stress-induced bipolar pea DNA helicase 47 is involved in protein synthesis and stimulated by phosphorylation with protein kinase C. Plant J. 44 (2005) 76-87
49. Vashisht A.A., and Tuteja N. Cold stress-induced pea DNA helicase 47 is homologous to eIF4A and inhibited by DNA-interacting ligands. Arch. Biochem. Biophysics 440 (2005) 79-90
50. Ward P., Equinet L., Packer J., and Doerig C. Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote. Bio. Med. Central Genomics 5 (2004) 79
51. Yang L., Yang J., Youliang H., and Liu Z.R. Phosphorylation of p68 RNA helicase regulates RNA binding by the C-terminal domain of the protein. Biochem. Biophys. Res. Comm. 314 (2004) 622-630