Plasmodium falciparum DNA helicase 60 is a schizont stage specific, bipolar and dual helicase stimulated by PKC phosphorylation

Molecular and Biochemical Parasitology

Volumn 144, Issue 2, 2005, Pages 133-141

  Pradhan, Arun ^a   Chauhan, Virander S ^a   Tuteja, Renu ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

Author keywords

DEAD box helicase; Malaria parasite; Schizont stage; Unwinding

Indexed keywords

DNA HELICASE 60; HELICASE; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ARTICLE; DNA METABOLISM; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; DNA RNA HYBRIDIZATION; IMMUNOFLUORESCENCE; PARASITE DEVELOPMENT; PHOSPHORYLATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA RNA HYBRIDIZATION; SCHIZONT;

ADENOSINE TRIPHOSPHATASES; ANIMALS; DNA; DNA HELICASES; DNA, PROTOZOAN; LIFE CYCLE STAGES; PHOSPHORYLATION; PLASMODIUM FALCIPARUM; PROTEIN KINASE C; RNA, PROTOZOAN;

PLASMODIUM FALCIPARUM;

EID: 27644591685     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2005.08.006     Document Type: Article

References (37)

1. M.C. Hall, and S.W. Matson Helicase motifs: the engine that powers DNA unwinding Mol Microbiol 34 1999 867 877
2. P. Linder, and M.C. Daugeron Are DEAD-box proteins becoming respectable helicases? Nat Struct Biol 7 2000 97 99
3. S. Rocak, and P. Linder DEAD-box proteins: the driving forces behind RNA metabolism Nat Rev Mol Cell Biol 5 2004 232 241
4. N. Tuteja, and R. Tuteja Prokaryotic and eukaryotic DNA helicases. Essential molecular motor proteins for cellular machinery Eur J Biochem 271 2004 1835 1848
5. A.E. Gorbalenya, E.V. Koonin, A.P. Donchenko, and V.M. Blinov A conserved NTP motif in putative helicases Nature 333 1988 22
6. O. Cordin, N.K. Tanner, M. Doere, P. Linder, and J. Banroques The newly discovered Q motif of DEAD-box RNA helicases regulates RNA-binding and helicase activity EMBO J 23 2004 2478 2487
7. N. Tuteja, and R. Tuteja Unraveling DNA helicases. Motif, structure, mechanism and function Eur J Biochem 271 2004 1849 1863
8. N. Tuteja, and R. Tuteja DNA helicases: the long unwinding road Nat Genet 13 1996 11 12
9. R. Tuteja, P. Malhotra, P. Song, N. Tuteja, and V.S. Chauhan Isolation and characterization of an eIF-4A homologue from Plasmodium cynomolgi Mol Biochem Parasitol 124 2002 79 83
10. R. Tuteja, N. Tuteja, P. Malhotra, and V.S. Chauhan Replication fork stimulated eIF-4A from Plasmodium cynomolgi unwinds DNA in the 3′ to 5′ direction and is inhibited by DNA-interacting compounds Arch Biochem Biophys 414 2003 108 114
11. A. Pradhan, V.S. Chauhan, and R. Tuteja A novel 'DEAD-box' DNA helicase from Plasmodium falciparum is homologous to p68 Mol Biochem Parasitol 140 2005 55 60
12. J. Sambrook, E. Fritsch, and T.I. Maniatis Molecular cloning: a laboratory manual 1989 Cold Spring Harbor Laboratory Press Cold Spring Harbor, New York
13. E. Harlow, and D. Lane Antibodies: a laboratory manual 1988 Cold Spring Harbor Laboratory Press Cold Spring Harbor, New York
14. C. Lambros, and J.P. Vanderberg Synchronization of Plasmodium falciparum erythrocytic stages in culture J Parasitol 65 1979 418 420
15. N. Tuteja, K. Rahman, R. Tuteja, and A. Falaschi Human DNA helicase V, a novel DNA unwinding enzyme from HeLa cells Nucleic Acids Res 21 1993 2323 2329
16. N. Tuteja, N.W. Huang, and D. Skopac Human DNA helicase IV is nucleolin, an RNA helicase modulated by phosphorylation Gene 160 1995 143 148
17. N. Tuteja, K. Rahman, R. Tuteja, A. Ochem, D. Skopac, and A. Falaschi DNA helicase III from HeLa cells: an enzyme that acts preferentially on partially unwound DNA duplexes Nucleic Acids Res 20 1992 5329 5337
18. T. Hunter, and B.M. Sefton Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci USA 77 1980 1311 1315
19. D.R. Dorer, A.C. Christensen, and D.H. Johnson A novel RNA helicase gene tightly linked to the Triplo-lethal locus of Drosophila Nucleic Acids Res 18 1990 5489 5494
20. R.D. Iggo, D.J. Jamieson, S.A. MacNeill, J. Southgate, J. McPheat, and D.P. Lane p68 RNA helicase: identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts Mol Cell Biol 11 1991 1326 1333
21. M. Okanami, T. Meshi, and M. Iwabuchi Characterization of a DEAD-box ATPase/RNA helicase protein of Arabidopsis thaliana Nucleic Acids Res 26 1998 2638 2643
22. G.M. Lamm, S.M. Nicol, F.V. Fuller-Pace, and A.I. Lamond p72: a human nuclear DEAD box protein highly related to p68 Nucleic Acids Res 24 1996 3739 3747
23. Y. Huang, and Z.-R. Liu The ATPase, RNA unwinding and RNA binding activities of recombinant p68 RNA helicase J Biol Chem 277 2002 12810 12815
24. S.P. Anand, and S.A. Khan Structure-specific DNA binding and bipolar helicase activities of PcrA Nucleic Acids Res 32 2004 3190 3197
25. F. Constantinesco, P. Forterre, E.V. Koonin, L. Aravind, and C.A. Elie Bipolar DNA helicase gene, herA, clusters with rad50, mre11 and nurA genes in thermophilic archaea Nucleic Acids Res 32 2004 1439 1447
26. A. Luking, U. Stahl, and U. Schmidt The protein family of RNA helicases Crit Rev Biochem Mol Biol 33 1998 259 296
27. S.W. Matson, D.W. Bean, and J.W. George DNA helicases: enzymes with essential roles in all aspects of DNA metabolism Bioessays 16 1994 13 22
28. E.E. Biswas, P.H. Chen, and S.B. Biswas Modulation of enzymatic activities of Escherichia coli DnaB helicase by single-stranded DNA-binding proteins Nucleic Acids Res 30 2002 2809 2816
29. Y. Ishimi DNA helicase activity is associated with an MCM4, -6, and -7 protein complex J Biol Chem 272 1997 24508 24513
30. X.H. Pham, M.K. Reddy, N.Z. Ehtesham, B. Matta, and N. Tuteja A DNA helicase from Pisum sativum is homologous to translation initiation factor and stimulates topoisomerase activity Plant J 24 2000 219 229
31. H. Hirling, M. Scheffner, T. Restle, and H. Stahl RNA helicase activity associated with the human p68 protein Nature 339 1989 562 564
32. M.K. Buelt, B.J. Glidden, and D.R. Storm Regulation of p68 RNA helicase by calmodulin and protein kinase C J Biol Chem 269 1994 29367 29370
33. N. Tuteja, M.K. Reddy, Y. Mudgil, B.S. Yadav, M. Chandok, and S.K. Sopory Pea DNA topoisomerase I is phosphorylated and stimulated by casein kinase 2 and protein kinase C Plant Physiol 132 2003 2108 2115
34. L. Yang, J. Yang, H. Youliang, and Z.-R. Liu Phosphorylation of p68 RNA helicase regulates RNA binding by the C-terminal domain of the protein Biochem Biophys Res Commun 314 2004 622 630
35. A. Kumar, A. Vaid, C. Syin, and P. Sharma PfPKB, a novel protein kinase B-like enzyme from Plasmodium falciparum. I. Identification, characterization, and possible role in parasite development J Biol Chem 279 2004 24255 24264
36. N. Tuteja, A.F. Beven, P.J. Shaw, and R. Tuteja A pea homologue of human DNA helicase I is localized within the dense fibrillar component of the nucleolus and stimulated by phosphorylation with CK2 and cdc2 protein kinases Plant J 25 2001 9 17
37. K. Tosh, S. Cheesman, P. Horrocks, and B. Kilbey Plasmodium falciparum: stage-related expression of topoisomerase I Exp Parasitol 91 1999 126 132