메뉴 건너뛰기




Volumn 216, Issue 2, 2008, Pages 551-557

Integrin α5-induced EGFR activation by prothrombin triggers hepatocyte apoptosis via the JNK signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA5 INTEGRIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRONECTIN RECEPTOR; PROTEIN SHC; PROTHROMBIN; STRESS ACTIVATED PROTEIN KINASE; TYROSINE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR; THROMBIN;

EID: 46049111212     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21429     Document Type: Article
Times cited : (12)

References (34)
  • 1
    • 4544302236 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells
    • Bill HM, Knudsen B, Moores SL, Muthuswamy SK, Rao VR, Brugge JS, Miranti CK. 2004. Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells. Mol Cell Biol 24:8586-8599.
    • (2004) Mol Cell Biol , vol.24 , pp. 8586-8599
    • Bill, H.M.1    Knudsen, B.2    Moores, S.L.3    Muthuswamy, S.K.4    Rao, V.R.5    Brugge, J.S.6    Miranti, C.K.7
  • 2
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 3
    • 3042653012 scopus 로고    scopus 로고
    • Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses
    • Cabodi S, Moro L, Erba EB, Di Stefano P, Turco E, Tarone G., et al. 2004. Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses. Biochem Soc Trans 32:438-442.
    • (2004) Biochem Soc Trans , vol.32 , pp. 438-442
    • Cabodi, S.1    Moro, L.2    Erba, E.B.3    Di Stefano, P.4    Turco, E.5    Tarone, G.6
  • 4
    • 34249654071 scopus 로고    scopus 로고
    • Growth inhibitory actions of prothrombin on normal hepatocyte: Influence of matrix
    • Carr BI, Kar S, Wang M, Wang Z. 2007. Growth inhibitory actions of prothrombin on normal hepatocyte: Influence of matrix. Cell Biol Int 31:929-938.
    • (2007) Cell Biol Int , vol.31 , pp. 929-938
    • Carr, B.I.1    Kar, S.2    Wang, M.3    Wang, Z.4
  • 5
    • 0035282334 scopus 로고    scopus 로고
    • mammalian MAP kinase signaling cascades
    • Chang L, Karin M. 2001. mammalian MAP kinase signaling cascades. Nature 410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 7
    • 0031892522 scopus 로고    scopus 로고
    • Disruption of fibronectin binding to the α5b1 integrin stimulates the expression of cyclin-dependent kinases and DNA synthesis through activation of extracellular signal-regulated kinase
    • Gong J, Ko TC, Brattain MG. 1998. Disruption of fibronectin binding to the α5b1 integrin stimulates the expression of cyclin-dependent kinases and DNA synthesis through activation of extracellular signal-regulated kinase. J Biol Chem 273:1662-1669.
    • (1998) J Biol Chem , vol.273 , pp. 1662-1669
    • Gong, J.1    Ko, T.C.2    Brattain, M.G.3
  • 8
    • 0033615657 scopus 로고    scopus 로고
    • Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplantin, sensitizes human ovarian cancer cell line
    • Hayakawa J, Ohmichi M, Kurachi H, Ikegami H, Kimura A, Matsuoka T, Jikihara H, Mercola D, Murata Y. 1999. Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplantin, sensitizes human ovarian cancer cell line. J Biol Chem 274:31648-31654.
    • (1999) J Biol Chem , vol.274 , pp. 31648-31654
    • Hayakawa, J.1    Ohmichi, M.2    Kurachi, H.3    Ikegami, H.4    Kimura, A.5    Matsuoka, T.6    Jikihara, H.7    Mercola, D.8    Murata, Y.9
  • 11
    • 33645564863 scopus 로고    scopus 로고
    • Structure-activity relationships of the human prothrombin kringle-2 peptide derivative NS A9: Anti-proliferative activity and cellular internalization
    • Hwang HS, Kim DW, Kim SS. 2006. Structure-activity relationships of the human prothrombin kringle-2 peptide derivative NS A9: Anti-proliferative activity and cellular internalization. Biochem J 395:165-172.
    • (2006) Biochem J , vol.395 , pp. 165-172
    • Hwang, H.S.1    Kim, D.W.2    Kim, S.S.3
  • 12
    • 0032054723 scopus 로고    scopus 로고
    • Signal transduction by the c-Jun N-terminal kinase (JNK) - From inflammation to development
    • Ip YT, Davis RJ. 1998. Signal transduction by the c-Jun N-terminal kinase (JNK) - From inflammation to development. Curr Opin Cell Biol 10:205-219.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 205-219
    • Ip, Y.T.1    Davis, R.J.2
  • 13
    • 0030860609 scopus 로고    scopus 로고
    • Regulation of tenascin-C, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growth
    • Jones PL, Crack J, Rabinovitch M. 1997. Regulation of tenascin-C, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growth. J Cell Biol 139: 279-293.
    • (1997) J Cell Biol , vol.139 , pp. 279-293
    • Jones, P.L.1    Crack, J.2    Rabinovitch, M.3
  • 14
    • 34648840300 scopus 로고    scopus 로고
    • α-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis
    • Kar S, Wang M, Carr BI. 2007. α-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis. Mol Cell Biochem 304:189-197.
    • (2007) Mol Cell Biochem , vol.304 , pp. 189-197
    • Kar, S.1    Wang, M.2    Carr, B.I.3
  • 15
    • 0030453194 scopus 로고    scopus 로고
    • Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
    • Miyamoto S, Teramoto H, Gutkind JS, Yamada KM. 1996. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors. J Cell Biol 135:1633-1642.
    • (1996) J Cell Biol , vol.135 , pp. 1633-1642
    • Miyamoto, S.1    Teramoto, H.2    Gutkind, J.S.3    Yamada, K.M.4
  • 16
    • 0032538798 scopus 로고    scopus 로고
    • Integrins induce activation of EGF receptor: Role in MAP kinase induction and adhesion-dependent cell survival
    • Moro L, Venturino M, Bozzo C, Silengo L, Altruda F, Beguinot L., Tarone G, Defilippi P. 1998. Integrins induce activation of EGF receptor: Role in MAP kinase induction and adhesion-dependent cell survival. EMBO J 17:6622-6632.
    • (1998) EMBO J , vol.17 , pp. 6622-6632
    • Moro, L.1    Venturino, M.2    Bozzo, C.3    Silengo, L.4    Altruda, F.5    Beguinot, L.6    Tarone, G.7    Defilippi, P.8
  • 19
    • 0030920914 scopus 로고    scopus 로고
    • The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin
    • Potapova O, Haghighi A, Bost F, Liu C, Birrer MJ, Gjerset R, Mercola D. 1997. The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin. J Biol Chem 272:14041-14044.
    • (1997) J Biol Chem , vol.272 , pp. 14041-14044
    • Potapova, O.1    Haghighi, A.2    Bost, F.3    Liu, C.4    Birrer, M.J.5    Gjerset, R.6    Mercola, D.7
  • 21
    • 0032476055 scopus 로고    scopus 로고
    • Control of cell cycle progression by fibronectin matrix architecture
    • Sechler JL, Schwarzbauer JE. 1998. Control of cell cycle progression by fibronectin matrix architecture. J Biol Chem 273:25533-25536.
    • (1998) J Biol Chem , vol.273 , pp. 25533-25536
    • Sechler, J.L.1    Schwarzbauer, J.E.2
  • 22
    • 33846236786 scopus 로고    scopus 로고
    • Differential activation of the JNK signal pathway by UV irradiation and glucose deprivation
    • Song JJ, Lee YJ. 2007. Differential activation of the JNK signal pathway by UV irradiation and glucose deprivation. Cell Signal 19:563-572.
    • (2007) Cell Signal , vol.19 , pp. 563-572
    • Song, J.J.1    Lee, Y.J.2
  • 25
    • 0029935418 scopus 로고    scopus 로고
    • Regulation of transcription by MAP kinase cascades
    • Treisman R. 1996. Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol 8:205-215.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 205-215
    • Treisman, R.1
  • 26
    • 0028641601 scopus 로고
    • Association of insulin receptor substrate-1 with integrins
    • Vuori K, Ruoslahti E. 1994. Association of insulin receptor substrate-1 with integrins. Science 266:1576-1578.
    • (1994) Science , vol.266 , pp. 1576-1578
    • Vuori, K.1    Ruoslahti, E.2
  • 27
    • 0029148360 scopus 로고
    • The growth inhibitory effects of vitamin K and their actions on gene expression
    • Wang Z, Wang M, Finn F, Carr BI. 1995. The growth inhibitory effects of vitamin K and their actions on gene expression. Hepatology 22:876-881.
    • (1995) Hepatology , vol.22 , pp. 876-881
    • Wang, Z.1    Wang, M.2    Finn, F.3    Carr, B.I.4
  • 28
    • 0034014304 scopus 로고    scopus 로고
    • Involvement of hepatocyte epidermal growth factor receptor mediated activation of mitogen-activated protein kinase signaling pathways in response to growth inhibition by a novel K vitamin
    • Wang Z, Wang M, Carr BI. 2000. Involvement of hepatocyte epidermal growth factor receptor mediated activation of mitogen-activated protein kinase signaling pathways in response to growth inhibition by a novel K vitamin. J Cell Physiol 183:338-346.
    • (2000) J Cell Physiol , vol.183 , pp. 338-346
    • Wang, Z.1    Wang, M.2    Carr, B.I.3
  • 30
    • 0042887252 scopus 로고    scopus 로고
    • The ins and outs of fibronectin matrix assembly
    • Wierzbicka-Patynowski I, Schwarzbauer JE. 2003. The ins and outs of fibronectin matrix assembly. J Cell Sci 116:3269-3276.
    • (2003) J Cell Sci , vol.116 , pp. 3269-3276
    • Wierzbicka-Patynowski, I.1    Schwarzbauer, J.E.2
  • 32
  • 33
    • 0034658083 scopus 로고    scopus 로고
    • Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells
    • Zain J, Huang YQ, Feng X, Nierodzik ML, Li JJ, Karpatkin S. 2000. Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells. Blood 95:3133-3138.
    • (2000) Blood , vol.95 , pp. 3133-3138
    • Zain, J.1    Huang, Y.Q.2    Feng, X.3    Nierodzik, M.L.4    Li, J.J.5    Karpatkin, S.6
  • 34
    • 0033214444 scopus 로고    scopus 로고
    • The EGF receptor as central transducer of heterologous signalling systems
    • Zwick E, Hackel PO, Prenzel N, Ullrich A. 1999. The EGF receptor as central transducer of heterologous signalling systems. TiPS 20:408-412.
    • (1999) TiPS , vol.20 , pp. 408-412
    • Zwick, E.1    Hackel, P.O.2    Prenzel, N.3    Ullrich, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.