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Volumn 3, Issue 3, 2008, Pages 251-263

Oritavancin: A potential weapon in the battle against serious Gram-positive pathogens

Author keywords

Glycopeptide; LY333328; Oritavancin; Staphylococcus aureus; Vancomycin resistant Enterococcus

Indexed keywords

CEFALEXIN; CEFTRIAXONE; DALBAVANCIN; DALFOPRISTIN PLUS QUINUPRISTIN; DAPTOMYCIN; DEXAMETHASONE; GENTAMICIN; LINEZOLID; ORITAVANCIN; PLACEBO; TEICOPLANIN; VANCOMYCIN; ANTIINFECTIVE AGENT; GLYCOPEPTIDE;

EID: 46049091025     PISSN: 17460913     EISSN: None     Source Type: Journal    
DOI: 10.2217/17460913.3.3.251     Document Type: Article
Times cited : (18)

References (65)
  • 1
    • 0038806687 scopus 로고    scopus 로고
    • The impact of antimicrobial resistance on health and economic outcomes
    • Cosgrove S, Carmeli Y: The impact of antimicrobial resistance on health and economic outcomes. Clin. Infect. Dis. 36, 1433-1437 (2003).
    • (2003) Clin. Infect. Dis , vol.36 , pp. 1433-1437
    • Cosgrove, S.1    Carmeli, Y.2
  • 2
    • 0037190708 scopus 로고    scopus 로고
    • Health and economic outcomes of vancomycin-resistant enterococci
    • Carmeli Y, Elopoulos G, Mozaffari E, Samore M: Health and economic outcomes of vancomycin-resistant enterococci. Arch. Intern. Med. 162, 2223-2228 (2002).
    • (2002) Arch. Intern. Med , vol.162 , pp. 2223-2228
    • Carmeli, Y.1    Elopoulos, G.2    Mozaffari, E.3    Samore, M.4
  • 3
    • 0032498719 scopus 로고    scopus 로고
    • Enterococcus faecium bacteremia: Does vancomycin resistance make a difference?
    • Stosor V, Peterson LR, Postelnick M, Noskin GA: Enterococcus faecium bacteremia: does vancomycin resistance make a difference? Arch. Intern. Med. 158, 522-527 (1998).
    • (1998) Arch. Intern. Med , vol.158 , pp. 522-527
    • Stosor, V.1    Peterson, L.R.2    Postelnick, M.3    Noskin, G.A.4
  • 4
    • 9644295892 scopus 로고    scopus 로고
    • system report, data summary from January 1992 through June 2004, issued October 2004
    • National Nosocomial Infections Surveillance NNIS
    • National Nosocomial Infections Surveillance (NNIS) system report, data summary from January 1992 through June 2004, issued October 2004. Am. J. Infect. Control 32, 470-485 (2004).
    • (2004) Am. J. Infect. Control , vol.32 , pp. 470-485
  • 5
    • 33645749939 scopus 로고    scopus 로고
    • The emergence of vancomycin-intermediate and vancomycin-resistant Staphylacoccus aureus
    • Appelbaum PC: The emergence of vancomycin-intermediate and vancomycin-resistant Staphylacoccus aureus. Clin. Microbiol. Infect. 12(S1), 16-23 (2006).
    • (2006) Clin. Microbiol. Infect , vol.12 , Issue.S1 , pp. 16-23
    • Appelbaum, P.C.1
  • 6
    • 39449103059 scopus 로고    scopus 로고
    • The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious Diseases Society of America
    • Spellberg B, Guidos R, Gilbert D et al.: The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America. Clin. Infect. Dis. 46, 155-164 (2008).
    • (2008) Clin. Infect. Dis , vol.46 , pp. 155-164
    • Spellberg, B.1    Guidos, R.2    Gilbert, D.3
  • 7
    • 1842428817 scopus 로고    scopus 로고
    • Characterization of a region specific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin
    • Lu W, Oberthur M, Leimkuhler C et al.: Characterization of a region specific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin. Proc. Natl Acad. Sci. 101, 4390-4395 (2004).
    • (2004) Proc. Natl Acad. Sci , vol.101 , pp. 4390-4395
    • Lu, W.1    Oberthur, M.2    Leimkuhler, C.3
  • 8
    • 0037266399 scopus 로고    scopus 로고
    • Mechanism of action of oritavancin and related glycopeptide antibiotics
    • Allen N, Nicas T: Mechanism of action of oritavancin and related glycopeptide antibiotics. FEMS Microbiol. Rev. 26, 511-532 (2003).
    • (2003) FEMS Microbiol. Rev , vol.26 , pp. 511-532
    • Allen, N.1    Nicas, T.2
  • 9
    • 8944258105 scopus 로고    scopus 로고
    • Reductive alkylation of glycopeptide antibiotics: Synthesis and antibacterial activity
    • Cooper R, Snyder N, Zweifel M et al.: Reductive alkylation of glycopeptide antibiotics: synthesis and antibacterial activity. J. Antibiotics 49, 575-581 (1996).
    • (1996) J. Antibiotics , vol.49 , pp. 575-581
    • Cooper, R.1    Snyder, N.2    Zweifel, M.3
  • 10
    • 39749162750 scopus 로고    scopus 로고
    • Oritavancin exhibits dual mode of action to inhibit cell-wall biosynthesis in Staphylococcus aureus
    • Kim SJ, Cegelski L, Stueber D et al.: Oritavancin exhibits dual mode of action to inhibit cell-wall biosynthesis in Staphylococcus aureus. J. Mol. Biol. 377(1), 281-293 (2008).
    • (2008) J. Mol. Biol , vol.377 , Issue.1 , pp. 281-293
    • Kim, S.J.1    Cegelski, L.2    Stueber, D.3
  • 11
    • 48949119213 scopus 로고    scopus 로고
    • Wang T-SA, Kahne DE, Walker S: Probing the mechanism of inhibition of bacterial peptidoglycan glycotransferases by glycopeptide analogs. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract C1-1474).
    • Wang T-SA, Kahne DE, Walker S: Probing the mechanism of inhibition of bacterial peptidoglycan glycotransferases by glycopeptide analogs. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract C1-1474).
  • 12
    • 48949119205 scopus 로고    scopus 로고
    • McKay G, Fadhil I, Beaulieu S et al.: Oritavancin disrupts transmembrane potential and membrane integrity concomitantly with cell killing in Staphylococcus aureus and vancomycin-resistant enterococci. Presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, San Francisco, CA, USA, 17-20 September, 2006. (Abstract C1-682).
    • McKay G, Fadhil I, Beaulieu S et al.: Oritavancin disrupts transmembrane potential and membrane integrity concomitantly with cell killing in Staphylococcus aureus and vancomycin-resistant enterococci. Presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, San Francisco, CA, USA, 17-20 September, 2006. (Abstract C1-682).
  • 13
    • 2542508472 scopus 로고    scopus 로고
    • In vitro activity of the new glycopeptide LY333328 against multiply resistant Gram-positive clinical isolates
    • Garcia-Garrote F, Cercenado E, Alcala L, Bouza E: In vitro activity of the new glycopeptide LY333328 against multiply resistant Gram-positive clinical isolates. Antimicrob. Agents Chemother. 42, 2452-2455 (1998).
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 2452-2455
    • Garcia-Garrote, F.1    Cercenado, E.2    Alcala, L.3    Bouza, E.4
  • 14
    • 48949119172 scopus 로고    scopus 로고
    • O'Connor R, Baines S, Freeman J, Wilcox M: In vitro susceptibility of genotypically distinct Clostridium difficile strains to oritavancin. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1618).
    • O'Connor R, Baines S, Freeman J, Wilcox M: In vitro susceptibility of genotypically distinct Clostridium difficile strains to oritavancin. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1618).
  • 15
    • 48949119178 scopus 로고    scopus 로고
    • Arhin F, Sarmiento I, Bailey A et al.: Activity of oritavancin against drug-resistant S. aureus in the presence of polysorbate-80. Presented at: 47th Interscience Conterence on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract D-242).
    • Arhin F, Sarmiento I, Bailey A et al.: Activity of oritavancin against drug-resistant S. aureus in the presence of polysorbate-80. Presented at: 47th Interscience Conterence on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract D-242).
  • 16
    • 48949119204 scopus 로고    scopus 로고
    • Sahm DF, Arhin FF, Moeck G, Draghi D: In vitro activity profile of oritavancin against resistant staphylococcal populations from a recent surveillance initiative. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1617).
    • Sahm DF, Arhin FF, Moeck G, Draghi D: In vitro activity profile of oritavancin against resistant staphylococcal populations from a recent surveillance initiative. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1617).
  • 17
    • 48949119177 scopus 로고    scopus 로고
    • Draghi DC, Grover PK, Moeck G et al.: In vitro activity profile of oritavancin (ORI) against organisms demonstrating key resistance profiles to other antimicrobial agents. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1613).
    • Draghi DC, Grover PK, Moeck G et al.: In vitro activity profile of oritavancin (ORI) against organisms demonstrating key resistance profiles to other antimicrobial agents. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1613).
  • 18
    • 42549094321 scopus 로고    scopus 로고
    • Anti-streptococcal activity profile of oritavancin, a potent lipoglycopeptide under development for use against Gram-positive infections
    • Presented at:, American Society for Microbiology Chicago, IL, USA, 17-20 September, Abstract E-1616
    • Draghi DC, Sahm DF, Arhin FF, Moeck G: Anti-streptococcal activity profile of oritavancin, a potent lipoglycopeptide under development for use against Gram-positive infections. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1616).
    • (2007) 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Draghi, D.C.1    Sahm, D.F.2    Arhin, F.F.3    Moeck, G.4
  • 19
    • 42549094321 scopus 로고    scopus 로고
    • Anti-enterococcal activity profile of oritavancin, a potent lipoglycopeptide under development for use against Gram-positive infections
    • Presented at:, American Society for Microbiology, Chicago, IL, USA, 17-20 September, Abstract E-1615
    • Draghi D, Sahm, DF, Arhin FF, Moeck G: Anti-enterococcal activity profile of oritavancin, a potent lipoglycopeptide under development for use against Gram-positive infections. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1615).
    • (2007) 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Draghi, D.1    Sahm, D.F.2    Arhin, F.F.3    Moeck, G.4
  • 20
    • 48949119203 scopus 로고    scopus 로고
    • Moeck G, Draghi D, Arhin F, Sahm D: In vitro activity profile of oritavancin against a broad spectrum of aerobic and anaerobic bacterial pathogens. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1612).
    • Moeck G, Draghi D, Arhin F, Sahm D: In vitro activity profile of oritavancin against a broad spectrum of aerobic and anaerobic bacterial pathogens. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1612).
  • 21
    • 42949088906 scopus 로고    scopus 로고
    • Effect of polysorbate-80 on oritavancin binding to plastic surfaces - implication for susceptibility testing
    • DOI: 10.1128/AAC.01513-07 , Epub ahead of print
    • Arhin F, Sarmiento I, Parr T, Moeck G: Effect of polysorbate-80 on oritavancin binding to plastic surfaces - implication for susceptibility testing. Antimicrob. Agents Chemother. DOI: 10.1128/AAC.01513-07 (2008) (Epub ahead of print).
    • (2008) Antimicrob. Agents Chemother
    • Arhin, F.1    Sarmiento, I.2    Parr, T.3    Moeck, G.4
  • 22
    • 48949119201 scopus 로고    scopus 로고
    • Influence of polysorbate-80 on susceptibility of Gram-positive bacteria to oritavancin
    • Presented at:, European Society of Clinical Microbiology and Infectious Diseases, Munich, Germany, March 31-April 4, Abstract P827
    • Arhin F, Sarmiento I, Bailey A, McKay G: Influence of polysorbate-80 on susceptibility of Gram-positive bacteria to oritavancin. Presented at: 17th European Congress of Clinical Microbiology and Infectious Diseases Abstracts. European Society of Clinical Microbiology and Infectious Diseases, Munich, Germany, March 31-April 4, 2007. (Abstract P827).
    • (2007) 17th European Congress of Clinical Microbiology and Infectious Diseases Abstracts
    • Arhin, F.1    Sarmiento, I.2    Bailey, A.3    McKay, G.4
  • 23
    • 48949119185 scopus 로고    scopus 로고
    • Performance Standard for Antimicrobial Susceptibility Testing
    • Clinical and Laboratory Standards Institute:, PA, USA
    • Clinical and Laboratory Standards Institute: Performance Standard for Antimicrobial Susceptibility Testing. Seventeenth Informational Supplement. CLSI document M100-S18. CLSI, PA, USA (2008).
    • (2008) Seventeenth Informational Supplement. CLSI document M100-S18. CLSI
  • 24
    • 0242437814 scopus 로고    scopus 로고
    • Antibacterial susceptibility of a vancomycin-resistant Staphylococcus aureus strain isolated at the Hershey Medical Center
    • Bozdogan B, Esel D, Whitener C et al.: Antibacterial susceptibility of a vancomycin-resistant Staphylococcus aureus strain isolated at the Hershey Medical Center. J. Antimicrob. Chemother. 52, 864-868 (2003).
    • (2003) J. Antimicrob. Chemother , vol.52 , pp. 864-868
    • Bozdogan, B.1    Esel, D.2    Whitener, C.3
  • 25
    • 0031967764 scopus 로고    scopus 로고
    • Efficacy of LY333328 against experimental methicillin-resistant Staphylococcus aureus endocarditis
    • Kaatz G, Seo S, Aeschlimann J et al.: Efficacy of LY333328 against experimental methicillin-resistant Staphylococcus aureus endocarditis. Antimicrob. Agents Chemother. 42, 981-983 (1998).
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 981-983
    • Kaatz, G.1    Seo, S.2    Aeschlimann, J.3
  • 26
    • 0032905225 scopus 로고    scopus 로고
    • Activity and diffusion of LY333328 in experimental endocarditis due to vancomycin-resistant Enterococcus faecalis
    • Saleh-mghir A, Lefort A, Petegnief Y et al.: Activity and diffusion of LY333328 in experimental endocarditis due to vancomycin-resistant Enterococcus faecalis. Antimicrob. Agents Chemother. 43, 115-120 (1999).
    • (1999) Antimicrob. Agents Chemother , vol.43 , pp. 115-120
    • Saleh-mghir, A.1    Lefort, A.2    Petegnief, Y.3
  • 27
    • 0033735126 scopus 로고    scopus 로고
    • Lefort A, Saleh-mghir A, Garry L et al.: Activity of LY333328 combined with gentamicin in vitro and in rabbit experimental endocarditis due to vancomycin-susceptible or -resistant Enterococcus faecalis. Antimicrob. Agents Chemothe. 44, 3017-3021 (2000).
    • Lefort A, Saleh-mghir A, Garry L et al.: Activity of LY333328 combined with gentamicin in vitro and in rabbit experimental endocarditis due to vancomycin-susceptible or -resistant Enterococcus faecalis. Antimicrob. Agents Chemothe. 44, 3017-3021 (2000).
  • 28
    • 0035011847 scopus 로고    scopus 로고
    • Effect of LY333328 against vancomycin-resistant Enterococcus faecium in a rat central venous catheter-associated infection model
    • Rupp M, Fey P, Longo M: Effect of LY333328 against vancomycin-resistant Enterococcus faecium in a rat central venous catheter-associated infection model. J. Antimicrob. Chemother. 47, 705-707 (2001).
    • (2001) J. Antimicrob. Chemother , vol.47 , pp. 705-707
    • Rupp, M.1    Fey, P.2    Longo, M.3
  • 29
    • 0034963038 scopus 로고    scopus 로고
    • Activity of LY333328 in experimental meningitis caused by a Streptococcus pneumoniae strain susceptible to penicillin
    • Gerber J, Smirnow A, Wellmer A et al.: Activity of LY333328 in experimental meningitis caused by a Streptococcus pneumoniae strain susceptible to penicillin. Antimicrob. Agents Chemother. 45, 2169-2172 (2001).
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 2169-2172
    • Gerber, J.1    Smirnow, A.2    Wellmer, A.3
  • 30
    • 0037764662 scopus 로고    scopus 로고
    • Experimental study of ly333328 (oritavancin), alone and in combination, in therapy of cephalosporin-resistant pneumococcal meningitis
    • Cabellos C, Fernandez A, Maiques J et al.: Experimental study of ly333328 (oritavancin), alone and in combination, in therapy of cephalosporin-resistant pneumococcal meningitis. Antimicrob. Agents Chemother. 47, 1907-1911 (2003).
    • (2003) Antimicrob. Agents Chemother , vol.47 , pp. 1907-1911
    • Cabellos, C.1    Fernandez, A.2    Maiques, J.3
  • 31
    • 48949119179 scopus 로고    scopus 로고
    • Lehoux D, Okusanya O, Ostiguy V et al.: PK-PD of oritavancin against S. pneumoniae in a murine-pneumonia infection model. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract A-49).
    • Lehoux D, Okusanya O, Ostiguy V et al.: PK-PD of oritavancin against S. pneumoniae in a murine-pneumonia infection model. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract A-49).
  • 32
    • 42549135775 scopus 로고    scopus 로고
    • Use of PK-PD principles to guide clinical drug development for oritavancin
    • Presented at:, American Society for Microbiology, Chicago, IL, USA, 17-20 September, Abstract A-51
    • Bhavnani S, Rubino C, Forrest A et al.: Use of PK-PD principles to guide clinical drug development for oritavancin. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract A-51).
    • (2007) 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Bhavnani, S.1    Rubino, C.2    Forrest, A.3
  • 33
    • 24244469738 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of single intravenous doses of ly333328 diphosphate (glycopeptide) in healthy men
    • Presented at:, American Society for Microbiology, San Diego, CA, USA, 24-27 September, Abstract A-55
    • Chien J, Allerheiligen S, Phillips D et al.: Safety and pharmacokinetics of single intravenous doses of ly333328 diphosphate (glycopeptide) in healthy men. Presented at: 38th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, San Diego, CA, USA, 24-27 September, 1998. (Abstract A-55).
    • (1998) 38th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Chien, J.1    Allerheiligen, S.2    Phillips, D.3
  • 34
    • 85057674644 scopus 로고    scopus 로고
    • Microbiological outcomes and pharmacokinetics of oritavancin in patients with Gram-positive bacteremia
    • Presented at:, European Society of Clinical Microbiology and Infectious Diseases, Milan, Italy, 21-24 April, Abstract P1091
    • De la Pena A, Chien J, Geiser J et al.: Microbiological outcomes and pharmacokinetics of oritavancin in patients with Gram-positive bacteremia. Presented at: 12th European Congress of Clinical Microbiology and Infectious Diseases Abstracts. European Society of Clinical Microbiology and Infectious Diseases, Milan, Italy, 21-24 April, 2002. (Abstract P1091).
    • (2002) 12th European Congress of Clinical Microbiology and Infectious Diseases Abstracts
    • De la Pena, A.1    Chien, J.2    Geiser, J.3
  • 35
    • 5044238495 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability of ascending single intravenous doses of oritavancin administered to healthy human subjects
    • Bhavnani S, Owen J, Loutit J et al.: Pharmacokinetics, safety, and tolerability of ascending single intravenous doses of oritavancin administered to healthy human subjects. Diag. Microbiol. Infect. Dis. 50, 95-102 (2004).
    • (2004) Diag. Microbiol. Infect. Dis , vol.50 , pp. 95-102
    • Bhavnani, S.1    Owen, J.2    Loutit, J.3
  • 36
    • 11244310896 scopus 로고    scopus 로고
    • Pharmacokinetics of oritavancin in plasma and skin blister fluid following administration of a 200-milligram, dose for 3 days or a single 800-milligram dose
    • Fetterly G, Ong C, Bhavnani S et al.: Pharmacokinetics of oritavancin in plasma and skin blister fluid following administration of a 200-milligram, dose for 3 days or a single 800-milligram dose. Antimicrob. Agents Chemother. 49, 148-152 (2005).
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 148-152
    • Fetterly, G.1    Ong, C.2    Bhavnani, S.3
  • 37
    • 24044442047 scopus 로고    scopus 로고
    • Oritavancin (LY333328): A dose-escalation safety and pharmacokinetics study in patients
    • Presented at:, European Society of Clinical Microbiology and Infectious Diseases, Istanbul, Turkey 1-4 April
    • Braun D, Chien J, Rarlow D et al.: Oritavancin (LY333328): a dose-escalation safety and pharmacokinetics study in patients. Presented at: 11th European Congress of Clinical Microbiology and Infectious Diseases Abstracts. European Society of Clinical Microbiology and Infectious Diseases, Istanbul, Turkey 1-4 April, 2001.
    • (2001) 11th European Congress of Clinical Microbiology and Infectious Diseases Abstracts
    • Braun, D.1    Chien, J.2    Rarlow, D.3
  • 39
    • 48949119194 scopus 로고    scopus 로고
    • LY333328 (oritavancin) glycopeptide accumulates in cultured macrophages but is only bacteriostatic towards intracellular Listeria monocytogenes
    • Presented at:, American Society for Microbiology, Chicago, IL, USA, 16-19 December, Abstract A-2069
    • Van Bambeke F, Carryn S, Snoeck A et al.: LY333328 (oritavancin) glycopeptide accumulates in cultured macrophages but is only bacteriostatic towards intracellular Listeria monocytogenes. Presented at: 41st Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 16-19 December, 2001. (Abstract A-2069).
    • (2001) 41st Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Van Bambeke, F.1    Carryn, S.2    Snoeck, A.3
  • 40
    • 0347448488 scopus 로고    scopus 로고
    • Is LY33328 glycopeptide a new cell-associated antibiotic? Comparative studies with vancomycin and azithromycin in a model of J774 mouse macrophages
    • Presented at:, European Society of Clinical Microbiology and Infectious Diseases, Istanbul, Turkey 1-4 April
    • Van Bambeke F, Snoeck A, Chanteux et al.: Is LY33328 glycopeptide a new cell-associated antibiotic? Comparative studies with vancomycin and azithromycin in a model of J774 mouse macrophages. Presented at: 11th European Congress of Clinical Microbiology and Infectious Diseases Abstracts. European Society of Clinical Microbiology and Infectious Diseases, Istanbul, Turkey 1-4 April, 2001.
    • (2001) 11th European Congress of Clinical Microbiology and Infectious Diseases Abstracts
    • Van Bambeke, F.1    Snoeck, A.2    Chanteux3
  • 41
    • 48949119189 scopus 로고    scopus 로고
    • Activity of the new glycopeptide oritavancin (LY333328) in a model of Staphylococcus aureus intraphagocytic infection in comparison with telithromycin (TEL) and moxifloxacin (MXF)
    • Presented at:, American Society for Microbiology, San Diego, CA, USA, 27-30 September, Abstract A-483
    • Seral C, Van Bambeke F, Tulkens P: Activity of the new glycopeptide oritavancin (LY333328) in a model of Staphylococcus aureus intraphagocytic infection in comparison with telithromycin (TEL) and moxifloxacin (MXF). Presented at: 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, San Diego, CA, USA, 27-30 September, 2002. (Abstract A-483).
    • (2002) 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Seral, C.1    Van Bambeke, F.2    Tulkens, P.3
  • 42
    • 48949119200 scopus 로고    scopus 로고
    • Barcia-Macay M, Seral C, Mingeot-Leclercq M et al.: Comparative activity of 12 antibiotics (abx) used at clinically-meaningful extracellular concentration against S. aureus in broth and in human thp-1 macrophages. Presented at: 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA 14-17 September, 2003. (Abstract A-1174).
    • Barcia-Macay M, Seral C, Mingeot-Leclercq M et al.: Comparative activity of 12 antibiotics (abx) used at clinically-meaningful extracellular concentration against S. aureus in broth and in human thp-1 macrophages. Presented at: 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA 14-17 September, 2003. (Abstract A-1174).
  • 43
    • 29244489458 scopus 로고    scopus 로고
    • Plasma and intrapulmonary concentrations of oritavancin and vancomycin in normal healthy adults
    • Presented at:, European Society of Clinical Microbiology and Infectious Diseases, Prague/Czech Republic 1-4 May, Abstract O254
    • Rodvold K, Gotfried M, Loutit J, Porter S: Plasma and intrapulmonary concentrations of oritavancin and vancomycin in normal healthy adults. Presented at: 14th European Congress of Clinical Microbiology and Infectious Diseases Abstracts. European Society of Clinical Microbiology and Infectious Diseases, Prague/Czech Republic 1-4 May, 2004. (Abstract O254).
    • (2004) 14th European Congress of Clinical Microbiology and Infectious Diseases Abstracts
    • Rodvold, K.1    Gotfried, M.2    Loutit, J.3    Porter, S.4
  • 44
    • 77957667019 scopus 로고    scopus 로고
    • Effect of hepatic impairment on the pharmacokinetics of the novel glycopeptide oritavancin
    • Presented at:, The American Association of Pharmaceutical Scientists, Baltimore, MD, USA, 7-10 November, Abstract T3313
    • Fetterly G, Owen J, Bhavnani S et al.: Effect of hepatic impairment on the pharmacokinetics of the novel glycopeptide oritavancin. Presented at: The American Association of Pharmaceutical Scientists Annual Meeating Abstracts. The American Association of Pharmaceutical Scientists, Baltimore, MD, USA, 7-10 November, 2004. (Abstract T3313).
    • (2004) The American Association of Pharmaceutical Scientists Annual Meeating Abstracts
    • Fetterly, G.1    Owen, J.2    Bhavnani, S.3
  • 45
    • 0030919648 scopus 로고    scopus 로고
    • Pharmacodynamic evaluation of a new glycopeptide, LY333328, and in vitro activity against Staphylococus aureus and Enterococcus faecium
    • Mercier R, Houlihan H, Rybak M: Pharmacodynamic evaluation of a new glycopeptide, LY333328, and in vitro activity against Staphylococus aureus and Enterococcus faecium. Antimicrob, Agents Chemother. 41, 1307-1312 (1997).
    • (1997) Antimicrob, Agents Chemother , vol.41 , pp. 1307-1312
    • Mercier, R.1    Houlihan, H.2    Rybak, M.3
  • 46
    • 0030820153 scopus 로고    scopus 로고
    • In vitro antibacterial activity of LY333328, a new semisynthetic glycopeptide
    • Biavasco F, Vignaroli C, Lupidi R et al.: In vitro antibacterial activity of LY333328, a new semisynthetic glycopeptide. Antimicrob. Agents Chemother. 41, 2165-2172 (1997).
    • (1997) Antimicrob. Agents Chemother , vol.41 , pp. 2165-2172
    • Biavasco, F.1    Vignaroli, C.2    Lupidi, R.3
  • 47
    • 0030920563 scopus 로고    scopus 로고
    • Time-kill curves for a semisynthetic glycopeptide, LY333328, against vancomycin-susceptible and vancomycin-resistant Enterococcus faecium strains
    • Zelenitsky S, Karlowsky J, Zhanel G et al.: Time-kill curves for a semisynthetic glycopeptide, LY333328, against vancomycin-susceptible and vancomycin-resistant Enterococcus faecium strains. Antimicrob. Agents Chemother. 41, 1407-1408 (1997).
    • (1997) Antimicrob. Agents Chemother , vol.41 , pp. 1407-1408
    • Zelenitsky, S.1    Karlowsky, J.2    Zhanel, G.3
  • 48
    • 0035118068 scopus 로고    scopus 로고
    • Activity of oritavancin (LY333328), an investigational glycopeptide, compared to that of vancomycin against multidrug-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model
    • Coyle E, Rybak M: Activity of oritavancin (LY333328), an investigational glycopeptide, compared to that of vancomycin against multidrug-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model. Antimicrob. Agents Chemother. 45, 706-709 (2001).
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 706-709
    • Coyle, E.1    Rybak, M.2
  • 49
    • 48949119195 scopus 로고    scopus 로고
    • Oritavancin time-kill, time-kill synergy, and postantibiotic effect determinations with S. aureus and enterococci
    • Presented at:, American Society for Microbiology, Chicago, IL, USA, 14-17 September, Abstract A-1170
    • Sahm D, Blosser R, Loutit J, Porter S: Oritavancin time-kill, time-kill synergy, and postantibiotic effect determinations with S. aureus and enterococci. Presented at: 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 14-17 September, 2003. (Abstract A-1170).
    • (2003) 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Sahm, D.1    Blosser, R.2    Loutit, J.3    Porter, S.4
  • 50
    • 48949119192 scopus 로고    scopus 로고
    • McKay G, Beaulieu S, Belley A et al.: In vitro time kill studies of oritavancin against drug-resistant isolates of Staphylococcus aureus and Enterococci, Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1614).
    • McKay G, Beaulieu S, Belley A et al.: In vitro time kill studies of oritavancin against drug-resistant isolates of Staphylococcus aureus and Enterococci, Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1614).
  • 51
    • 0038334898 scopus 로고    scopus 로고
    • Pharmacodynamics of oritavancin (LY333328) in a neutropenic-mouse thigh model of Staphylococcus aureus infection
    • Boylan CJ, Campanale K, Iversen PW et al.: Pharmacodynamics of oritavancin (LY333328) in a neutropenic-mouse thigh model of Staphylococcus aureus infection. Antimicrob. Agents Chemother. 47, 1700-1706 (2003).
    • (2003) Antimicrob. Agents Chemother , vol.47 , pp. 1700-1706
    • Boylan, C.J.1    Campanale, K.2    Iversen, P.W.3
  • 52
    • 48949119181 scopus 로고    scopus 로고
    • Efficacy of LY333328 in a rat model of Staphylococcus aureus (SA) central venous catheter (CVC)-associated infection
    • Presented at:, American Society for Microbiology, San Diego, CA, USA, 24-27 September, Abstract F-111
    • Rupp M, Ulphani J: Efficacy of LY333328 in a rat model of Staphylococcus aureus (SA) central venous catheter (CVC)-associated infection. Presented at: 38th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, San Diego, CA, USA, 24-27 September, 2008. (Abstract F-111).
    • (2008) 38th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Rupp, M.1    Ulphani, J.2
  • 53
    • 48949119004 scopus 로고    scopus 로고
    • Lehoux D, Okusanya O, Ostiguy V et al.: PK-PD of oritavancin against S. pneumoniae in a musine-pneumonia infection model. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract A-49).
    • Lehoux D, Okusanya O, Ostiguy V et al.: PK-PD of oritavancin against S. pneumoniae in a musine-pneumonia infection model. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract A-49).
  • 54
    • 0033735126 scopus 로고    scopus 로고
    • Activity of LY333328 combined with gentamicin in vitro and in vivo in rabbit experimental endocarditis due to vancomycin-susceptible or -resistant Enterococcus faecalis
    • Lefort AA, Saleh-Jghir A, Garry L, Carbon C, Fantin B: Activity of LY333328 combined with gentamicin in vitro and in vivo in rabbit experimental endocarditis due to vancomycin-susceptible or -resistant Enterococcus faecalis. Antimicrob. Agents Chemother. 44, 3017-3021 (2000).
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 3017-3021
    • Lefort, A.A.1    Saleh-Jghir, A.2    Garry, L.3    Carbon, C.4    Fantin, B.5
  • 55
    • 33644638214 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic relationships describing the efficacy of oritavancin in patients with Staphylococcus aureus bacteremia
    • Bhavnani S, Passarell J, Owen J et al.: Pharmacokinetic-pharmacodynamic relationships describing the efficacy of oritavancin in patients with Staphylococcus aureus bacteremia. Antimicrob. Agents Chemother. 50, 994-1000 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 994-1000
    • Bhavnani, S.1    Passarell, J.2    Owen, J.3
  • 56
    • 12944275538 scopus 로고    scopus 로고
    • Antistaphylococcal activity of dalbavancin, an experimental glycopeptide
    • Lin G, Creditc, K, Ednie L, Appelbaum P: Antistaphylococcal activity of dalbavancin, an experimental glycopeptide. Antimicrob. Agents Chemother. 49, 770-772 (2005).
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 770-772
    • Lin, G.1    Creditc, K.2    Ednie, L.3    Appelbaum, P.4
  • 57
    • 0033743317 scopus 로고    scopus 로고
    • Activities of LY333328 and vancomycin administered alone or in combination with gentamicin against three strains of vancomycin-intermediate Staphylococcus aureus in an in vitro pharmacodynamic infection model
    • Aeschlimann J, Allen G, Hershberger E, Rybak M: Activities of LY333328 and vancomycin administered alone or in combination with gentamicin against three strains of vancomycin-intermediate Staphylococcus aureus in an in vitro pharmacodynamic infection model Antimicrob. Agents Chemother. 44, 2991-2998 (2000).
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 2991-2998
    • Aeschlimann, J.1    Allen, G.2    Hershberger, E.3    Rybak, M.4
  • 58
    • 0031662779 scopus 로고    scopus 로고
    • Comparison of inhibitory and bactericidal activities and postantibiotic effects of LY333328 and ampicillin used singly and in combination against vancomycin-resistant Enterococcus faecium
    • Baltch A, Smith R, Ritz W, Bopp L: Comparison of inhibitory and bactericidal activities and postantibiotic effects of LY333328 and ampicillin used singly and in combination against vancomycin-resistant Enterococcus faecium. Antimicrob. Agents Chemother. 42, 2564-2568 (1998).
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 2564-2568
    • Baltch, A.1    Smith, R.2    Ritz, W.3    Bopp, L.4
  • 59
    • 48949119191 scopus 로고    scopus 로고
    • McKay G, Beaulieu S, Parr T Jr, Moeck G: In vitro post antibiotic effect studies of oritavancin against S. aureus and enterococci. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract A-50).
    • McKay G, Beaulieu S, Parr T Jr, Moeck G: In vitro post antibiotic effect studies of oritavancin against S. aureus and enterococci. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract A-50).
  • 60
    • 48949119196 scopus 로고    scopus 로고
    • Belley A, McKay G, Beaulieu S et al.: Oritavancin kills Staphylococcus aureus in slow-growing planktonic and biofilm states. Presented at: 46th Interscience Conference an Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, San Francisco, CA, USA, 17-20 September, 2006. (Abstract B-0661).
    • Belley A, McKay G, Beaulieu S et al.: Oritavancin kills Staphylococcus aureus in slow-growing planktonic and biofilm states. Presented at: 46th Interscience Conference an Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, San Francisco, CA, USA, 17-20 September, 2006. (Abstract B-0661).
  • 61
    • 48949119202 scopus 로고    scopus 로고
    • Belley A, Neesham-Grenon E, Parr T Jr, Moeck G: Pharmacokinetic concentrations of oritavancin kill stationary-phase and biofilm Staphylococcus aureus in vitro. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1620).
    • Belley A, Neesham-Grenon E, Parr T Jr, Moeck G: Pharmacokinetic concentrations of oritavancin kill stationary-phase and biofilm Staphylococcus aureus in vitro. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 17-20 September, 2007. (Abstract E-1620).
  • 62
    • 0346449383 scopus 로고    scopus 로고
    • Equivalence of shorter course therapy with oritavancin vs. vancomycin/cephalexin in complicated skin/skin structure infections
    • Presented at:, American Society for Microbiology, Chicago, IL, USA, 16-19 December, Abstract UL-18
    • Wasilewski M, Disch D, McGill J et al.: Equivalence of shorter course therapy with oritavancin vs. vancomycin/cephalexin in complicated skin/skin structure infections. Presented at: 41st Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL, USA, 16-19 December, 2001. (Abstract UL-18).
    • (2001) 41st Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Wasilewski, M.1    Disch, D.2    McGill, J.3
  • 63
    • 0347709911 scopus 로고    scopus 로고
    • Phase 3 trial comparing 3-7 days of oritavancin vs. 10-14 days of vancomycin/ cephalexin in the treatment of patients with complicated skin and skin structure infections
    • Presented at:, American Society for Microbiology, Chicago, IL. USA 14-17 September, Abstract L-739a
    • Giamarellou G, O'Riordan W, Harris H, et al.: Phase 3 trial comparing 3-7 days of oritavancin vs. 10-14 days of vancomycin/ cephalexin in the treatment of patients with complicated skin and skin structure infections. Presented at: 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts. American Society for Microbiology, Chicago, IL. USA 14-17 September, 2003. (Abstract L-739a).
    • (2003) 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstracts
    • Giamarellou, G.1    O'Riordan, W.2    Harris, H.3
  • 64
    • 13444313833 scopus 로고    scopus 로고
    • Phase 2 trial comparing four regimens of oritavancin vs. comparator in the treatment of patients with S. aureus bacteremia
    • Presented at:, European Society of Clinical Microbiology and Infectious Diseases, Prague/Czech Republic, 1-4 May, Abstract P541
    • Loutit J, O'Riordan W, San Juan J et al.: Phase 2 trial comparing four regimens of oritavancin vs. comparator in the treatment of patients with S. aureus bacteremia. Presented at: 14th European Congress of Clinical Microbiology and Infectious Diseases Abstracts. European Society of Clinical Microbiology and Infectious Diseases, Prague/Czech Republic, 1-4 May, 2004. (Abstract P541).
    • (2004) 14th European Congress of Clinical Microbiology and Infectious Diseases Abstracts
    • Loutit, J.1    O'Riordan, W.2    San Juan, J.3
  • 65
    • 18244402385 scopus 로고    scopus 로고
    • Mixed-lipid storage disorder induced in macrophages and fibroblasts by oritavancin (LY333328), a new glycopeptide antibiotic with exceptional cellular accumulation
    • Van Bambeke F, Saffran J, Mingeot-Leclercq MP, Tulkens P: Mixed-lipid storage disorder induced in macrophages and fibroblasts by oritavancin (LY333328), a new glycopeptide antibiotic with exceptional cellular accumulation. Antimicrob. Agents Chemother. 49, 1695-1700 (2005).
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 1695-1700
    • Van Bambeke, F.1    Saffran, J.2    Mingeot-Leclercq, M.P.3    Tulkens, P.4


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