Effect of radiation protraction in intensity-modulated radiation therapy with direct aperture optimization: A phantom study

Physics in Medicine and Biology

Volumn 53, Issue 12, 2008, Pages 3279-3292

  Kuperman, V Y ^a,c   Ventura, A M ^a   Sommerfeldt, M ^b  

^a JA Haley Medical Center   (United States)

^b Standard Imaging   (United States)

^c HALIFAX MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OPTIMIZATION; RADIATION;

DELIVERY-TIME; DIRECT APERTURE OPTIMIZATION; FRACTION SIZE; INTENSITY-MODULATED RADIATION THERAPY; INVERSE PLANNING; PHANTOM STUDIES; PROSTATE CANCERS; TREATMENT PLANNING;

PHYSICAL THERAPY;

ARTICLE; BEAM THERAPY; CELL FRACTIONATION; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LINEAR ACCELERATOR; MIXED LYMPHOCYTE CULTURE; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION; RADIATION DOSE DISTRIBUTION; TREATMENT PLANNING;

DOSE FRACTIONATION; LINEAR MODELS; MOTION; PHANTOMS, IMAGING; RADIOTHERAPY, INTENSITY-MODULATED; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

EID: 45949110347     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/53/12/014     Document Type: Article

References (17)

1. Altman M B, Chmura S J, Deasy J O and Roeske J C 2006 Optimization of the temporal pattern of radiation: an IMRT based study Int. J. Radiat. Oncol. Biol. Phys. 66 898-905
2. Benedict S H, Lin P S, Zwicker R D, Huang D T and Schmidt-Ullrich R K A 1997 The biological effectiveness of intermittent irradiation as a function of overall treatment time: development of correction factors for linac-based stereotactic radio surgery Int. J. Radiat. Oncol. Biol. Phys. 37 765-9
3. Brenner D J and Hall E J 1991 Conditions for the equivalence of continuous and pulsed low dose rate brachytherapy Int. J. Radiat. Oncol. Biol. Phys. 20 181-90
4. Brenner D J and Hall E J 1999 Fractionation and protraction for radiotherapy of prostate carcinoma Int. J. Radiat. Oncol. Biol. Phys. 43 1095-101
5. Dale R G, Fowler J F and Jones B 1999 A new incomplete-repair model based on a reciprocal time pattern of sublethal damage repair Acta Oncol. 38 919-29
6. Fowler J F 2002 Repair between dose fractions: a simper method of analyzing and reporting apparently biexponential repair Radiat. Res. 158 141-51
7. Fowler J F, Welsh J S and Howard S P 2004 Loss of biological effect in prolonged fraction delivery Int. J. Radiat. Oncol. Biol. Phys 59 242-9
8. King C R and Fowler J F 2001 A simple analytic derivation suggest that prostate cancer ration is low Int. J. Radiat. Oncol. Biol. Phys. 51 213-4
9. Kupelian P A et al 2002 Preliminary observations on biochemical relapse-free survival rates after short-course intensity modulated radiotherapy (70 Gy at 2.5 Gy/fraction) for localized prostate cancer Int. J. Radiat. Oncol. Biol. Phys. 53 904-12
10. Lea D E and Gatcheside D G 1942 The mechanism of the induction of radiation of chromosome aberrations in tradescantia J. Genet. 44 216-45
11. Pollack A et al 2006 Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial Int. J. Radiat. Oncol. Biol. Phys. 64 518-26
12. Shepard D M, Earl M A, Li X A and Yu C 2002 Direct aperture optimization: a turnekey solution to step-and-shoot IMRT Med. Phys. 29 1007-18
13. Shibamoto Y, Ito M, Suge C, Ogino H and Hara M 2004 Recovery from sublethal damage during intermittent exposure in cultured tumors cells: implications for dose modifications in radiosurgery and IMRT Int. J. Radiat. Oncol. Biol. Phys. 59 1484-90
14. Wang J Z, Li X A, D'Souza W D and Stewart R D 2003 Impact of prolonged fraction delivery times on tumor control: a note on caution for intensity-modulated radiation therapy (IMRT) Int. J. Radiat. Oncol. Biol. Phys. 57 543-52
15. Weichselbaum R R, Rotmensch J, Ahmed-Swan S and Beckett M A 1989 Radiobiological characteristics of 53 human tumor cell lines Int. J. Radiat. Biol. 56 553-60
16. Welsh J S, Howard S P and Fowler J F 2003 Dose rate in external beam radiotherapy for prostate cancer: an overlooked confounding variable? Urology 62 204-6
17. Yu C 1995 Intensity-modulated arc therapy with dynamic multileaf collimator, an alternative to tomotherapy Phys. Med. Biol. 40 1435-49