Repair between dose fractions: A simpler method of analyzing and reporting apparently biexponential repair

Radiation Research

Volumn 158, Issue 2, 2002, Pages 141-151

  Fowler, Jack F ^a  

^a Dept Human Oncology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA REPAIR; DNA STRAND BREAKAGE; LUNG; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; RADIATION PHYSICS; RADIOBIOLOGY; SPINAL CORD; DNA DAMAGE; HUMAN; METHODOLOGY; RADIATION DOSE FRACTIONATION; RADIATION EXPOSURE; RADIOTHERAPY; REGRESSION ANALYSIS; TIME;

ANIMALIA;

DNA DAMAGE; DNA REPAIR; DOSE FRACTIONATION; HUMANS; RADIOTHERAPY; REGRESSION ANALYSIS; TIME FACTORS;

EID: 0036022363     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2002)158[0141:RBDFAS]2.0.CO;2     Document Type: Article

References (45)

1. The kinetics of repair for sublethal radiation-induced damage in the pig epidermis: An interpretation based on a fast and a slow component of repair
2. Impact of spinal cord repair kinetics on the practice of altered fractionation schedules
3. The kinetics of repair of sublethal damage in the rat cervical spinal cord during fractionated irradiations
4. Kinetics of repair in the spinal cord of the rat
5. Repair kinetics in pig epidermis: An analysis based on two separate rates of repair
6. Repair kinetics in mouse lung after multiple X-ray fractions per day
7. Repair, repopulation and cell cycle distribution in rat foot skin
8. Recovery kinetics of X-ray damage in mouse skin: The influence of dose per fraction
9. Repair kinetics of radiation damage in the developing rat cervical spinal cord
10. The kinetics of repair in mouse lung after fractionated irradiation
11. Repair capacity and kinetics of human skin during fractionated radiotherapy: Erythema, desquamation, and telangiectasia after 3 and 5 years' follow-up
12. Recovery from radiation damage in mouse lung: Interpretation in terms of two rates of repair
13. Repair rate in mouse lung after clinically relevant radiation doses per fraction
14. High dose rate (HDR) and low dose rate (LDR) interstitial irradiation (IRT) of the rat spinal cord
15. Radiation tolerance of rat spinal cord to pulsed dose rate brachy-therapy: The impact of differences in temporal dose distribution
16. A theory of the action of radiation on biological materials capable of recovery. 1. The time-intensity factor
17. The mechanism of the induction by radiation of chromosome aberrations in Tradescantia
18. Misrejoining of double-strand breaks after X-irradiation: Relating moderate to very high doses by a Markov model
19. Recent data obtained by pulsed field gel electrophoresis suggests two kinds of double-strand breaks
20. The link between low-LET dose-response relations and the underlying kinetics of damage production/repair/misrepair
21. The repair-misrepair model of cell survival
22. The repair-misrepair model in radiobiology: Comparison to other methods
23. Lethal and potentially lethal lesions induced by radiation - A unified repair model
24. A benchmark of cell survival models using survival curves for human cells after completion of repair of potentially lethal damage
25. Is repair of radiation damage in DNA second-order rather than first-order? A simpler explanation of apparently bi- or multi-exponential repair
26. DNA repair kinetics after exposure to X-irradiation and to internal beta-rays in CHO cells
27. Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation
28. Acute reaction parameters for human oropharyngeal mucosa
29. X-ray induced conductivity in insulating materials
30. On the Williams-Watt function of dielectric relaxation
31. Clinical implications of hyperbolic (reciprocal straight line) repair of sublethal radiation damage
32. The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L 5178Y cells. II Repair
33. Repair of X-ray induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: Joining of correct and incorrect ends
34. Saturable repair models of radiation action in mammalian cells
35. A new incomplete-repair model based on a "reciprocal-time" pattern of sublethal damage repair
36. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses
37. The linear quadratic formula and progress in fractionated radiotherapy
38. An 'incomplete repair' model for survival after fractionated and continuous irradiations
39. Is the experience with CHART compatible with experimental data? A new model of repair kinetics and computer simulations
40. A test for the saturation of repair hypothesis for shouldered survival curves
41. Half-life values for DNA double-strand break rejoining in yeast can vary by more than an order of magnitude depending on the irradiation conditions
42. Repair of ionizing radiation induced double strand breaks (dsb) at the c-myc locus in comparison to the overall gene
43. Repair capacity and kinetics for human mucosa and epithelial tumours in the head and neck: Clinical data on the effect of changing the time interval between multiple fractions per day in radiotherapy
44. Repair half-times estimated from observations of treatment-related morbidity after CHART or conventional radiotherapy in head and neck cancer
45. Entities ought not to be multiplied except from necessity