The biological effectiveness of intermittent irradiation as a function of overall treatment time: Development of correction factors for linac-based stereotactic radiotherapy

International Journal of Radiation Oncology Biology Physics

Volumn 37, Issue 4, 1997, Pages 765-769

  Benedict, Stanley H ^a   Lin, Peck Sun ^a   Zwicker, Robert D ^a   Huang, David T ^a   Schmidt Ullrich, Rupert K A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Stereotactic radiosurgery; Stereotactic radiotherapy; U 87 MG

Indexed keywords

ARTICLE; CELL SURVIVAL; DOSE CALCULATION; DOSE TIME EFFECT RELATION; GAMMA RADIATION; GLIOMA CELL; HUMAN; HUMAN CELL; IRRADIATION; PRIORITY JOURNAL; RADIATION DOSE DISTRIBUTION; RADIATION DOSE FRACTIONATION; RADIOSURGERY; STEREOTAXIC SURGERY;

BRAIN NEOPLASMS; CELL SURVIVAL; GLIOMA; HUMANS; RADIOMETRY; RADIOSURGERY; RADIOTHERAPY DOSAGE; RELATIVE BIOLOGICAL EFFECTIVENESS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0030968338     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(97)00023-0     Document Type: Article

References (13)

1. Alexander, E. E.; Loeffler, J. S.; Lunsford, L. D. Stereotactic radiosurgery. New York: McGraw-Hill Inc.; 1993: 67-76.
2. Benedict, S. H.; Lin, P.-S.; Zwicker, R. D.; Khandelwal, S.; Broaddus, W. C.; Schmidt-Ullrich, R. Stereotactic radiosurgery: The relative biological effect of continuous vs. intermittent radiation exposures. Radiat. Oncol. Invest. 2:219-223; 1994/1995.
3. DeSalles, A. A. F.; Goetsch, S. J. Stereotactic surgery and radiosurgery. Madison, WI: Medical Physics Publishing Co.; 1993:210-221.
4. Hall, E. J.; Brenner, D. J. The radiobiology of radiosurgery: Rationale for different treatment regimes for AVM and malignancies. Int. J. Radiat. Oncol. Biol. Phys. 25:381-385; 1993.
5. Heller, D. P.; Raaphorst, G. P. The kinetics of cellular recovery in exponential and plateau growth phase human glioma cells following γ-irradiation. Int. J. Radiat. Oncol. Biol. Phys. 30:383-390; 1994.
6. Larson, D. A.; Flickinger, J. C.; Loeffler, J. S. The radiobiology of radiosurgery. Int. J. Radiat. Oncol. Biol. Phys. 25:557-561; 1993.
7. Mauch, P. M.; Loeffler, J. S. Radiation oncology: Technology and biology. Philadelphia, PA: W. B. Saunders Co.; 1994:200-202.
8. Radiation Therapy Oncology Group, RTOG 93-05. A phase III trial comparing the use of radiosurgery followed by conventional radiotherapy with BCNU to conventional radiotherapy with BCNU for supratentorial glioblastoma multiforme. Philadelphia, PA: RTOG; 1994.
9. Schell, M. C.; Smith, V.; Larson, D. A.; Wu, A.; Flickinger, J. C. Evaluation of radiosurgery techniques with cumulative dose volume histograms in linac-based stereotactic external beam irradiation. Int. J. Radiat. Oncol. Biol. Phys. 20:1325-1330; 1991.
10. Stamato, T.; Guerriero, S.; N. Denko, N. Two methods for assaying DNA double-strand break repair in mammalian cells by asymmetric field inversion gel electrophoresis. Radiat. Res. 133:60-66; 1993.
11. VanAnkeren, S. C.; Murray, D.; Meyn, R. E. Induction and rejoining of γ-ray-induced DNA single and double-strand breaks in Chinese hamster AA8 cells and in two radiosensitive clones. Radiat. Res. 116:511-525; 1988.
12. Webb, S. The physics of three-dimensional radiation therapy - Conformal radiotherapy, radiosurgery and treatment planning. Philadelphia, PA: Institute of Physics Publishing; 1993:135-171.
13. Wheeler, K. T.; Nelson, G. B.; Terrell, K. E.; Wallen, C. A. Regulation of DNA repair kinetics in proliferative and quiescent tumor cells. Int. J. Radiat. Biol. 54:245-255; 1988.