Assessment of vitamin E concentrations in serum and cerebrospinal fluid of horses following oral administration of vitamin E

American Journal of Veterinary Research

Volumn 69, Issue 6, 2008, Pages 785-790

  Higgins, Jamie K ^a   Puschner, Birgit ^b   Kass, Philip H ^a   Pusterla, Nicola ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; EMCELLE TOCOPHEROL;

ANIMAL FOOD; ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DOSE RESPONSE; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DOSE COMPARISON; DRUG MECHANISM; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORSE; MALE; NONHUMAN; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

ADMINISTRATION, ORAL; ALPHA-TOCOPHEROL; ANIMALS; DIETARY SUPPLEMENTS; FEMALE; HORSES; MALE; RANDOM ALLOCATION; STATISTICS, NONPARAMETRIC; VITAMIN E;

ANIMALIA; EQUIDAE;

EID: 45949106823     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.69.6.785     Document Type: Article

References (22)

1. Delanty N, Dichter MA. Oxidative injury in the nervous system. Acta Neurol Scand 1998;98:145-153.
2. Kontush K, Schekatolina S. Vitamin E in neurodegenerative disorders: Alzheimer's disease. Ann N Y Acad Sci 2004;1031:249-262.
3. Baalsrud KJ, Overnes G. Influence of vitamin E and selenium supplement on antibody production in horses. Equine Vet J 1986;18:472-474.
4. Roneus BO, Hakkarainen RVJ, Lindholm CA, et al. Vitamin E requirements of adult Standardbred horses evaluated by tissue depletion and repletion. Equine Vet J 1986;18:50-58.
5. Steiss JE, Traber MG, Williams MA, et al. Alpha tocopherol concentrations in clinically normal adult horses. Equine Vet J 1994;26:417-419.
6. Craig AM, Blythe LL, Rowe KE, et al. Evaluation of the oral vitamin E absorption test in horses. Am J Vet Res 1991;52:912-916.
7. Kane E. Vitamin E is essential equine nutrient. DVM Magazine 2004;May:10-15.
8. Vatassery GT, Adityanjee MD, Quach HT, et al. Alpha and gamma tocopherols in cerebrospinal fluid and serum from older, male, human subjects. J Am Coll Nutr 2004;23:233-238.
9. Pappert EJ, Tangney CC, Goetz CG, et al. Alpha-tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: dose-response study and correlations with plasma levels. Neurology 1996;47:1037-1042.
10. Bertrone J, Horspool L. Equine clinical pharmacology. Philadelphia: Saunders, 2004.
11. Craig AM, Blythe LL, Rowe KE, et al. Variability of α-tocopherol values associated with procurement, storage, and freezing of equine serum and plasma samples. Am J Vet Res 1992;53:2228-2234.
12. Brown TJ, Duewer DL, Kline MC, et al. The stability of retinol, alpha-tocopherol, trans-lycopene, and trans-beta-carotene in liquid-frozen and lyophilized serum. Clin Chim Acta 1998; 276:75-87.
13. Nutrient requirements of horses. Washington, DC: National Research Council, National Academy of Sciences, 1989.
14. Orsini JTD, ed. Manual of equine emergencies: treatment and procedures, 2nd ed. Philadelphia: Saunders, 2003.
15. McMurray CHB. Application of a high-performance liquid chromatography fluorescence method for the rapid determination of alpha-tocopherol in the plasrfia of cattle and pigs in its comparison with direct fluorescence and high-performance liquid chromatography-ultraviolet detection methods. J Chromatogr 1979;178:525-531.
16. Schryver HH, Hintz FH. Vitamins. In: Robinson NE, ed. Current therapy in equine medicine. Philadelphia: Saunders 1983;84.
17. Hintz HF. Nutrition and equine performance. J Nutr 1994;124(suppl 12):2723S-2729S.
18. Vatassery GT, Angerhofer CK, Know CA, et al. Concentrations of vitamin E in various neuroanatomical regions and subcellular fractions, and the uptake of vitamin E by specific areas, of rat brain. Biochim Biophys Acta 1984;792:118-122.
19. Vatassery GT, Fahn S, Kuskowski MA. Alpha-tocopherol in CSF of subjects taking high-dose vitamin E in the DATATOP study. Parkinson Study Group. Neurology 1998;50:1900-1902.
20. Craig AM, Blythe LL, Lassen ED, et al. Variations of serum vitamin E, cholesterol, and total serum lipid concentrations in horses during a 72-hour period. Am J Vet Res 1989;50:1527-1531.
21. Stadtman ER. Role of oxidant species in aging. Curr Med Chem 2004;11:1105-1112.
22. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000;408:239-247.