The stability of retinol, α-tocopherol, trans-lycopene, and trans-β-carotene in liquid-frozen and lyophilized serum

Clinica Chimica Acta

Volumn 276, Issue 1, 1998, Pages 75-87

  Brown Thomas, Jeanice ^a   Duewer, David L ^a   Kline, Margaret C ^a   Sharpless, Katherine E ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

Carotenoids; Human serum; Liquid chromatography; Storage duration; Vitamins

Indexed keywords

ALPHA TOCOPHEROL; BETA CAROTENE; CAROTENOID; LYCOPENE; RETINOL;

ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG STABILITY; FREEZE DRYING; HUMAN; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SERUM; STORAGE; TEMPERATURE;

ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; BETA CAROTENE; BLOOD BANKS; BLOOD SPECIMEN COLLECTION; CAROTENOIDS; DRUG STABILITY; FREEZE DRYING; FREEZING; HUMANS; TIME FACTORS; VITAMIN A; VITAMIN E;

EID: 0031866074     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(98)00103-X     Document Type: Article

References (22)

1. Comstock GW, Alberg AJ, Helzlsouer KJ Reported effects of long-term freezer storage on concentrations of retinol, β-carotene, and α-tocopherol in serum or plasma summarized. Clin Chem. 39:1993;1075-1078.
2. Mathews-Roth MM, Stampfer MJ Some factors affecting determination of carotenoids in serum. Clin Chem. 30:1984;459-461.
3. Thurnham DI, Flora PS Stability of individual carotenoids, retinol, and tocopherol in stored plasma. Clin Chem. 34:1988;1947.
4. Craft NE, Brown ED, Smith JC Jr. Effects of storage and handling conditions on concentrations of individual carotenoids, retinol, and tocopherol in plasma. Clin Chem. 34:1988;44-48.
5. Nierenberg DW Serum and plasma β-carotene levels measured with an improved method of high-performance liquid chromatography. J Chromatogr Biomed Appl. 339:1985;273-284.
6. Ahola I, Alfthan G, Gref CG Stability of the fatty acid composition and vitamin concentrations in serum samples thawed twice from -70°C. Clin Chem. 34:1988;1923.
7. Smith AH, Waller KD Serum beta-carotene in persons with cancer and their immediate families. Am J Epidemiol. 133:1991;661-671.
8. Clevidence BA, Ballard-Barbash R Tocopherol contents of lipoproteins from frozen plasma separated by affinity chromatography. Lipids. 26:1991;72-78.
9. Driskell WJ, Lackey AD, Hewett JS, Bashor MM Stability of vitamin A in frozen sera. Clin Chem. 31:1985;871-872.
10. Parkinson CE, Gal I Factors affecting the laboratory management of human serum and liver vitamin A analyses. Clin Chim Acta. 40:1972;83-90.
11. Miller KW, Lorr NA, Yang CS Simultaneous determination of plasma retinol, α-tocopherol, lycopene, α-carotene, and β-carotene by high performance liquid chromatography. Anal Biochem. 138:1984;340-345.
12. Comstock GW, Norkus EP, Hoffman SC, Xu MW, Helzlsouer KJ Stability of ascorbic acid, carotenoids, retinol, and tocopherols in plasma stored at -70°C for 4 years. Cancer Epidemiol Biomarkers Prev. 4:1995;505-507.
13. Gunter EW, Driskell WJ, Yeager PR Stability of vitamin E in long-term stored serum. Clin Chim Acta. 175:1988;329-336.
14. Duewer DL, Brown Thomas J, Kline MCet al. NIST/NCI micronutrients measurement quality assurance program: measurement repeatabilities and reproducibilities for fat-soluble vitamin-related compounds in human sera. Anal Chem. 69:1997;1406-1413.
15. Certificate of Analysis, standard reference material 968a: Fat-soluble Vitamins in Human Serum. Gaithersburg, MD: Standard Reference Materials Program, National Institute of Standards and Technology, 1992.
16. Certificate of Analysis, standard reference material 968b: Fat-soluble Vitamins and Cholesterol in Human Serum. Gaithersburg, MD: Standard Reference Materials Program, National Institute of Standards and Technology, 1995.
17. Brown Thomas J, Kline MC, Schiller SBet al. Certification of fat-soluble vitamins, carotenoids, and cholesterol in human serum: Standard Reference Material 968b. Fresenius J Anal Chem. 356:1996;1-9.
18. MacCrehan WA, Schönberger E Determination of retinol, α-tocopherol, and β-carotene. Clin Chem. 33:1987;158-192.
19. 18 stationary phase. J Chromatogr B. 678:1996;187-195.
20. Sharpless KE, Brown Thomas J, Turley CP, Brewster MA. Vitamin A and vitamin E. In: Pesce AJ, Kaplan LA, editors. Laboratory medicine: a scientific and managerial infobase, version 2.6. Cincinnati, OH: Pesce Kaplan Publishers, July 1997.
21. Epler KS, Ziegler RG, Craft NE Liquid chromatographic method for the determination of carotenoids, retinoids and tocopherols in human serum and in food. J Chromatogr Biomed Appl. 619:1993;37-48.
22. Sharpless KS, Duewer DL Population distributions and intralaboratory reproducibility for fat-soluble vitamin-related compounds in human serum. Anal Chem. 67:1995;4416-4422.