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Volumn 4, Issue 2, 2008, Pages 148-157

A call to cellular and humoral arms: Enlisting cognate T cell help to develop broad-spectrum vaccines against influenza A

Author keywords

B cell; Cognate; Epitope; Help; Influenza; T cell

Indexed keywords

IMMUNOLOGICAL ADJUVANT; INACTIVATED VACCINE; INFLUENZA VACCINE; LIVE VACCINE; M2E PROTEIN; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS HEMAGGLUTININ; VIRUS SIALIDASE;

EID: 45849127634     PISSN: 15548600     EISSN: 15548619     Source Type: Journal    
DOI: 10.4161/hv.4.2.5169     Document Type: Note
Times cited : (36)

References (132)
  • 1
    • 17944363471 scopus 로고    scopus 로고
    • Preparing for the next pandemic
    • Osterholm MT. Preparing for the next pandemic. N EngI J Med 2005; 352:1839-42.
    • (2005) N EngI J Med , vol.352 , pp. 1839-1842
    • Osterholm, M.T.1
  • 2
    • 0018365378 scopus 로고
    • In vitro antibody response to influenza virus. T cell dependence of secondary response to hemagglutinin
    • Anders EM, Peppard PM, Burns WH, White DO. In vitro antibody response to influenza virus. T cell dependence of secondary response to hemagglutinin. J Immunol 1979; 123:1356-61.
    • (1979) J Immunol , vol.123 , pp. 1356-1361
    • Anders, E.M.1    Peppard, P.M.2    Burns, W.H.3    White, D.O.4
  • 3
    • 0023199837 scopus 로고
    • Immunologic response to influenza virus neuraminidase is influenced by prior experience with the associated viral hemagglutinin: Reduced generation of neuramindase specific Helper T cells in hemagglutinin primed mice
    • Johansson BE, Moran TM, Bona CA, Kilbourne ED. Immunologic response to influenza virus neuraminidase is influenced by prior experience with the associated viral hemagglutinin: Reduced generation of neuramindase specific Helper T cells in hemagglutinin primed mice. J Immunol 1987; 139:2015-9.
    • (1987) J Immunol , vol.139 , pp. 2015-2019
    • Johansson, B.E.1    Moran, T.M.2    Bona, C.A.3    Kilbourne, E.D.4
  • 5
    • 0032853287 scopus 로고    scopus 로고
    • What are the prospects for a universal influenza vaccine?
    • Kilbourne ED. What are the prospects for a universal influenza vaccine? Nat Med 1999; 5:1119-20.
    • (1999) Nat Med , vol.5 , pp. 1119-1120
    • Kilbourne, E.D.1
  • 6
    • 31344441324 scopus 로고
    • Studies of two kinds of virus particles which comprise influenza A2 virus strains. Reactivity with virus inhibitors in normal sera
    • Choppin P, and Tamm I. Studies of two kinds of virus particles which comprise influenza A2 virus strains. Reactivity with virus inhibitors in normal sera. J Exp Med 1960; 112:921.
    • (1960) J Exp Med , vol.112 , pp. 921
    • Choppin, P.1    Tamm, I.2
  • 7
    • 0024573756 scopus 로고
    • Purified influenza virus hemagglutinin and neuraminidase are equivalent in stimulation of antibody response but induce contrasting types of immunity to infection
    • Johansson B, Bucher D, and Kilbourne E. Purified influenza virus hemagglutinin and neuraminidase are equivalent in stimulation of antibody response but induce contrasting types of immunity to infection. J Virology 1989; 63:1239.
    • (1989) J Virology , vol.63 , pp. 1239
    • Johansson, B.1    Bucher, D.2    Kilbourne, E.3
  • 8
    • 0014914270 scopus 로고
    • Influenza virus proteins. Analysis of polypeptides of the virion and identification of spike glycoproteins
    • Compans R, Klenk H-D, Caliguiri L, Choppin P. Influenza virus proteins. Analysis of polypeptides of the virion and identification of spike glycoproteins. Virology 1970; 42:880.
    • (1970) Virology , vol.42 , pp. 880
    • Compans, R.1    Klenk, H.-D.2    Caliguiri, L.3    Choppin, P.4
  • 9
    • 0017139702 scopus 로고
    • Comparative efficacy of neuraminidase-specific and conventional influenza virus vaccines in induction of antibody to neuraminidase in humans
    • Kilbourne ED. Comparative efficacy of neuraminidase-specific and conventional influenza virus vaccines in induction of antibody to neuraminidase in humans. J Infect Dis, 1976; 134: 385.
    • (1976) J Infect Dis , vol.134 , pp. 385
    • Kilbourne, E.D.1
  • 10
    • 0020072063 scopus 로고
    • Secretory and systemic immunological response in children infected with live attenuated influenza A virus vaccines
    • Murphy BR, Nelson DL, Wright PF, Tierney EL, Phelan MA, Chanock RM. Secretory and systemic immunological response in children infected with live attenuated influenza A virus vaccines. Infect Immun 1982; 36:1102-8.
    • (1982) Infect Immun , vol.36 , pp. 1102-1108
    • Murphy, B.R.1    Nelson, D.L.2    Wright, P.F.3    Tierney, E.L.4    Phelan, M.A.5    Chanock, R.M.6
  • 11
    • 0020581131 scopus 로고
    • Hemagglutinin-specific antibody responses in immunoglobulin G, A, and M isotypes as measured by enzyme-linked immunosorbent assay after primary or secondary infection of humans with influenza A virus
    • Burlington DB, Clements ML, Meiklejohn G, Phelan M, Murphy BR. Hemagglutinin-specific antibody responses in immunoglobulin G, A, and M isotypes as measured by enzyme-linked immunosorbent assay after primary or secondary infection of humans with influenza A virus. Infect Immun 1983; 41: 540-5
    • (1983) Infect Immun , vol.41 , pp. 540-545
    • Burlington, D.B.1    Clements, M.L.2    Meiklejohn, G.3    Phelan, M.4    Murphy, B.R.5
  • 12
    • 0017341579 scopus 로고
    • Functional specificity of thymus-dependent lymphocytes
    • Paul WE and Benacerraf B. Functional specificity of thymus-dependent lymphocytes. Science 1977; 195:1293
    • (1977) Science , vol.195 , pp. 1293
    • Paul, W.E.1    Benacerraf, B.2
  • 13
    • 0022504418 scopus 로고
    • Functional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin
    • Scherle PA, Gerhard W. Functional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin. J Exp Med 1986; 164:1114-28.
    • (1986) J Exp Med , vol.164 , pp. 1114-1128
    • Scherle, P.A.1    Gerhard, W.2
  • 14
    • 0018745584 scopus 로고
    • T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin
    • Russell SM, Liew FY. T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin. Nature 1979; 280:147-8.
    • (1979) Nature , vol.280 , pp. 147-148
    • Russell, S.M.1    Liew, F.Y.2
  • 16
    • 0037456637 scopus 로고    scopus 로고
    • N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication
    • Liu W, Li H, Chen Y-H. N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication. FEMS Immunol Med Microbiol 2003; 35:141-6.
    • (2003) FEMS Immunol Med Microbiol , vol.35 , pp. 141-146
    • Liu, W.1    Li, H.2    Chen, Y.-H.3
  • 18
    • 0024340382 scopus 로고
    • Identification of PR-8 Ml protein influenza high-yield reassortants by Ml-specific monoclonal antibodies
    • Johansson BE, Bucher DJ, Pokorny BA and Kilbourne ED. Identification of PR-8 Ml protein influenza high-yield reassortants by Ml-specific monoclonal antibodies. Virology 1989; 171:634-6.
    • (1989) Virology , vol.171 , pp. 634-636
    • Johansson, B.E.1    Bucher, D.J.2    Pokorny, B.A.3    Kilbourne, E.D.4
  • 21
    • 0029822596 scopus 로고    scopus 로고
    • Evaluation of a recombinant hemagglutinin expressed in insect cells as an influenza vaccine in young and elderly adults
    • Powers D, Smith G, Anderson E, Kennedy D, Hackett C, Wilkinson B, et al. Evaluation of a recombinant hemagglutinin expressed in insect cells as an influenza vaccine in young and elderly adults. J Infect Dis 1996; 173:1467-70.
    • (1996) J Infect Dis , vol.173 , pp. 1467-1470
    • Powers, D.1    Smith, G.2    Anderson, E.3    Kennedy, D.4    Hackett, C.5    Wilkinson, B.6
  • 22
    • 0027282159 scopus 로고
    • Implications for vaccine production of influenza A virus hemagglutinin polymorphism. Pleotropic antigenic variant of A/Shangai/11/87 (H3N2) virus selected as high-yield reassortant
    • Kilbourne ED, Johansson BE, Moran TM, Wu S, Pokorny BA, Xu X, and Cox N. Implications for vaccine production of influenza A virus hemagglutinin polymorphism. Pleotropic antigenic variant of A/Shangai/11/87 (H3N2) virus selected as high-yield reassortant. J Gen Virol 1993; 74:1311-6.
    • (1993) J Gen Virol , vol.74 , pp. 1311-1316
    • Kilbourne, E.D.1    Johansson, B.E.2    Moran, T.M.3    Wu, S.4    Pokorny, B.A.5    Xu, X.6    Cox, N.7
  • 23
    • 0020480083 scopus 로고
    • The sequence of the nucleoprotein gene of human influenza A virus, strain A/NT/60/68
    • Huddleston JA, Brownlee GG. The sequence of the nucleoprotein gene of human influenza A virus, strain A/NT/60/68. Nucleic Acids Res 1982; 10:1029-38.
    • (1982) Nucleic Acids Res , vol.10 , pp. 1029-1038
    • Huddleston, J.A.1    Brownlee, G.G.2
  • 24
    • 0021752426 scopus 로고
    • Antigenic structure of the influenza B virus hemagglutinin: Nucleotide sequence analysis of antigenic variants selected with monoclonal antibodies
    • Berton MT, Naeve CW, Webster RG. Antigenic structure of the influenza B virus hemagglutinin: nucleotide sequence analysis of antigenic variants selected with monoclonal antibodies. J Virol 1984; 52: 919-27.
    • (1984) J Virol , vol.52 , pp. 919-927
    • Berton, M.T.1    Naeve, C.W.2    Webster, R.G.3
  • 26
    • 0023082271 scopus 로고
    • Contemporary concepts of antigenic variation
    • Cruse JM, Lewis RB. Contemporary concepts of antigenic variation. Contra Micro Immuno 1987; 8:1-19.
    • (1987) Contra Micro Immuno , vol.8 , pp. 1-19
    • Cruse, J.M.1    Lewis, R.B.2
  • 27
    • 0015059073 scopus 로고
    • The in vivo production of "new" influenza A viruses
    • Campbell CH, Webster RG, and Breese SS Jr. The in vivo production of "new" influenza A viruses. Virology 1971; 44:317-28.
    • (1971) Virology , vol.44 , pp. 317-328
    • Campbell, C.H.1    Webster, R.G.2    Breese Jr., S.S.3
  • 30
    • 23844534838 scopus 로고    scopus 로고
    • Immunization against influenza A virus: Comparison of conventional inactivated, live-attenuated and recombinant baculovirus produced purified hemagglutinin and neuraminidase vaccines in a murine model system
    • Brett IC, Johansson BE. Immunization against influenza A virus: comparison of conventional inactivated, live-attenuated and recombinant baculovirus produced purified hemagglutinin and neuraminidase vaccines in a murine model system. Virology 2005; 339:273-80.
    • (2005) Virology , vol.339 , pp. 273-280
    • Brett, I.C.1    Johansson, B.E.2
  • 31
    • 0442323299 scopus 로고    scopus 로고
    • Influenza virus: Immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines
    • Cox RJ, Brokstad KA, Ogra P. Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines. Scand J Immunol 2004; 59:1-15.
    • (2004) Scand J Immunol , vol.59 , pp. 1-15
    • Cox, R.J.1    Brokstad, K.A.2    Ogra, P.3
  • 32
    • 1842685790 scopus 로고    scopus 로고
    • Cold-adapted, live attenuated influenza vaccine
    • Glezen WP. Cold-adapted, live attenuated influenza vaccine. Expert Rev Vaccines 2004; 3:131-9.
    • (2004) Expert Rev Vaccines , vol.3 , pp. 131-139
    • Glezen, W.P.1
  • 33
    • 0017669707 scopus 로고
    • A controlled double-blind comparison of the reactogenicity, immunogenicity, and protective efficacy of whole-virus and split-product influenza vaccines in children
    • Gross P, Ennis F, Gaerlan L, Denson L, Denning C, Schiffman D. A controlled double-blind comparison of the reactogenicity, immunogenicity, and protective efficacy of whole-virus and split-product influenza vaccines in children. J Inf Dis 1977; 136:623.
    • (1977) J Inf Dis , vol.136 , pp. 623
    • Gross, P.1    Ennis, F.2    Gaerlan, L.3    Denson, L.4    Denning, C.5    Schiffman, D.6
  • 35
    • 1842612619 scopus 로고    scopus 로고
    • Antigenic and molecular analysis of influenza A (H3N2) virus strains isolated from a localised influenza outbreak in South Africa in 2003
    • Besselaar TG, Botha L, McAnerney JM, Schoub BD. Antigenic and molecular analysis of influenza A (H3N2) virus strains isolated from a localised influenza outbreak in South Africa in 2003. J Med Virol 2004; 73:71-8.
    • (2004) J Med Virol , vol.73 , pp. 71-78
    • Besselaar, T.G.1    Botha, L.2    McAnerney, J.M.3    Schoub, B.D.4
  • 36
    • 33947605771 scopus 로고
    • Effect of priming infection on serologic response to whole and subunit influenza virus vaccines in animals
    • McLaren C, Verbonitz MW, Daniel S, Guggs G, Ennis E Effect of priming infection on serologic response to whole and subunit influenza virus vaccines in animals. J Immuno 1977; 125:2679
    • (1977) J Immuno , vol.125 , pp. 2679
    • McLaren, C.1    Verbonitz, M.W.2    Daniel, S.3    Guggs, G.4    Ennis, E.5
  • 37
    • 0017609914 scopus 로고
    • Serologic responses after two sequential doses of influenza A/New Jersey/76 virus vaccine in normal young adults
    • Wise T, Polin R, Mazur M, Ennis F. Serologic responses after two sequential doses of influenza A/New Jersey/76 virus vaccine in normal young adults. J Inf Dis 1977; 136:5496.
    • (1977) J Inf Dis , vol.136 , pp. 5496
    • Wise, T.1    Polin, R.2    Mazur, M.3    Ennis, F.4
  • 38
    • 0023546371 scopus 로고
    • Antigen-presenting B cells and helper T cells cooperatively mediate intravirionic antigenic competition between influenza A virus surface glycoproteins
    • Johansson BE, Moran TM, Kilbourne ED. Antigen-presenting B cells and helper T cells cooperatively mediate intravirionic antigenic competition between influenza A virus surface glycoproteins. PNAS USA 1987; 84:6869-73.
    • (1987) PNAS USA , vol.84 , pp. 6869-6873
    • Johansson, B.E.1    Moran, T.M.2    Kilbourne, E.D.3
  • 39
    • 0035964320 scopus 로고    scopus 로고
    • The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: Implications for peptide vaccination
    • Rasmussen IB, Lunde E, Michaelsen TE, Bogen B, Sandlie I. The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: implications for peptide vaccination. Proc Natl Acad Sci USA 2001; 98:10296-301.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10296-10301
    • Rasmussen, I.B.1    Lunde, E.2    Michaelsen, T.E.3    Bogen, B.4    Sandlie, I.5
  • 40
    • 0021956416 scopus 로고
    • Antigen-specific interaction between T and B cells
    • Lanzavecchia A. Antigen-specific interaction between T and B cells. Nature 1985; 314: 537.
    • (1985) Nature , vol.314 , pp. 537
    • Lanzavecchia, A.1
  • 41
    • 0029068576 scopus 로고
    • A review of attenuation of influenza viruses by genetic manipulation
    • Belshe RB. A review of attenuation of influenza viruses by genetic manipulation. Am J Respir Crit Care Med 1995; 152:S72-5.
    • (1995) Am J Respir Crit Care Med , vol.152
    • Belshe, R.B.1
  • 43
    • 33947605771 scopus 로고
    • Effect of priming infection on serologic response to whole and subunit influenza virus vaccines in animals
    • McLaren C, Verbonitz MW, Daniel S, Guggs G, Ennis F. Effect of priming infection on serologic response to whole and subunit influenza virus vaccines in animals. J Immuno 1977; 125:2679
    • (1977) J Immuno , vol.125 , pp. 2679
    • McLaren, C.1    Verbonitz, M.W.2    Daniel, S.3    Guggs, G.4    Ennis, F.5
  • 44
    • 0033913482 scopus 로고    scopus 로고
    • Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine
    • Belshe R, Gruber W, Mendelman P, Cho I, Reisinger K, Block S, et al. Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine. J Pediatrics 2000; 136:168-175.
    • (2000) J Pediatrics , vol.136 , pp. 168-175
    • Belshe, R.1    Gruber, W.2    Mendelman, P.3    Cho, I.4    Reisinger, K.5    Block, S.6
  • 45
    • 0017139702 scopus 로고
    • Comparative efficacy of neuraminidase-specific and conventional influenza virus vaccines in the induction of anti-neuraminidase antibody in man
    • Kilbourne E. Comparative efficacy of neuraminidase-specific and conventional influenza virus vaccines in the induction of anti-neuraminidase antibody in man. J Inf Dis 1976; 134:384.
    • (1976) J Inf Dis , vol.134 , pp. 384
    • Kilbourne, E.1
  • 47
    • 0035825607 scopus 로고    scopus 로고
    • Treanor JJ, Wilkinson BE, Masseoud F, Hu-Primmer j, Batraglia R, O'Brien D, Wolff M, Rabinovich G, Blackwelder W, Katz JM. Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans. Vaccine 2001;19:1732-7.
    • Treanor JJ, Wilkinson BE, Masseoud F, Hu-Primmer j, Batraglia R, O'Brien D, Wolff M, Rabinovich G, Blackwelder W, Katz JM. Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans. Vaccine 2001;19:1732-7.
  • 49
    • 3042823259 scopus 로고    scopus 로고
    • Control of influenza virus infection by immunity to conserved viral features
    • Epstein SL. Control of influenza virus infection by immunity to conserved viral features. Expert Rev And Infect Ther 2003; 1:627-38.
    • (2003) Expert Rev And Infect Ther , vol.1 , pp. 627-638
    • Epstein, S.L.1
  • 51
    • 33645399959 scopus 로고    scopus 로고
    • Safety and immunogenicity of an inactivated subvirion influenza A (H5N1) vaccine
    • Treanor JJ, Campbell JD, Zangwill KM, Rowe T, Wolff M. Safety and immunogenicity of an inactivated subvirion influenza A (H5N1) vaccine. N Engl J Med 2006; 354:1343-51.
    • (2006) N Engl J Med , vol.354 , pp. 1343-1351
    • Treanor, J.J.1    Campbell, J.D.2    Zangwill, K.M.3    Rowe, T.4    Wolff, M.5
  • 52
    • 0035897889 scopus 로고    scopus 로고
    • Safety and antigenicity of non-adjuvanted and MF-59 adjuvanted/Duck/Singapore/97 (H5N3) vaccine: A randomized trial of two potential vaccines against H5N1 influenza
    • Nicholson KG, Colegate AE, Podda A, et al. Safety and antigenicity of non-adjuvanted and MF-59 adjuvanted/Duck/Singapore/97 (H5N3) vaccine: a randomized trial of two potential vaccines against H5N1 influenza. Lancet 2001; 357:1937-43.
    • (2001) Lancet , vol.357 , pp. 1937-1943
    • Nicholson, K.G.1    Colegate, A.E.2    Podda, A.3
  • 53
    • 33645409589 scopus 로고    scopus 로고
    • Vaccines against avian influenza-a race against time
    • Poland GA. Vaccines against avian influenza-a race against time. N Engl J Med 2006; 354:1411-3.
    • (2006) N Engl J Med , vol.354 , pp. 1411-1413
    • Poland, G.A.1
  • 54
    • 0035969787 scopus 로고    scopus 로고
    • Developing vaccines againsr pandemic influenza
    • Wood JM. Developing vaccines againsr pandemic influenza. Philos Trans R Soc Lond B Biol Sci 2001; 356:1953-60.
    • (2001) Philos Trans R Soc Lond B Biol Sci , vol.356 , pp. 1953-1960
    • Wood, J.M.1
  • 56
    • 33745232537 scopus 로고    scopus 로고
    • An Inactivated Subvirion Influenza A (H5N1) Vaccine
    • Johansson BE, Brett IC, Focosi D, Poland GA. An Inactivated Subvirion Influenza A (H5N1) Vaccine. NEJM 2006; 354:2724-5.
    • (2006) NEJM , vol.354 , pp. 2724-2725
    • Johansson, B.E.1    Brett, I.C.2    Focosi, D.3    Poland, G.A.4
  • 57
    • 0027475844 scopus 로고
    • Antibody tesponse to M2 protein of influenza A virus expressed in insect cells
    • Black RA, Rota PA, Gorodkova N, Klenk HD, Kendal AP. Antibody tesponse to M2 protein of influenza A virus expressed in insect cells. J Gen Virol 1993; 74:143-6.
    • (1993) J Gen Virol , vol.74 , pp. 143-146
    • Black, R.A.1    Rota, P.A.2    Gorodkova, N.3    Klenk, H.D.4    Kendal, A.P.5
  • 58
    • 0038402706 scopus 로고    scopus 로고
    • Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2
    • Mozdzanowska K, Feng J, Eid M, Kragol G, Cudic M, Otvos L Jr, Gerhard W. Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2. Vaccine 2003; 21:2616-26.
    • (2003) Vaccine , vol.21 , pp. 2616-2626
    • Mozdzanowska, K.1    Feng, J.2    Eid, M.3    Kragol, G.4    Cudic, M.5    Otvos Jr, L.6    Gerhard, W.7
  • 59
    • 0033845127 scopus 로고    scopus 로고
    • The senescence-accelerated mouse shows aging-related defects in cellular but not humoral immunity against influenza virus infection
    • Dong L, Mori I, Hossain MJ, Kimura Y. The senescence-accelerated mouse shows aging-related defects in cellular but not humoral immunity against influenza virus infection, J Infect Dis 2000; 182:391-6.
    • (2000) J Infect Dis , vol.182 , pp. 391-396
    • Dong, L.1    Mori, I.2    Hossain, M.J.3    Kimura, Y.4
  • 60
    • 0842300355 scopus 로고    scopus 로고
    • Recognition of homo- and heterosubtypic variants of influenza A viruses by human CD8+ T lymphocytes
    • Boon AC, de Mutsert G, van Baarle D, et al. Recognition of homo- and heterosubtypic variants of influenza A viruses by human CD8+ T lymphocytes. J Immunol 2004; 172:2453-60.
    • (2004) J Immunol , vol.172 , pp. 2453-2460
    • Boon, A.C.1    de Mutsert, G.2    van Baarle, D.3
  • 61
    • 33845205893 scopus 로고    scopus 로고
    • Primary influenza A virus infection induces cross-protective immunity against a lethal infection with a heterosubtypic virus strain in mice
    • Kreijtz JH, Bodewes R, van Amerongen G, Kuiken T, Fouchier RA, Osrerhaus AD, Rimmelzwaan GF. Primary influenza A virus infection induces cross-protective immunity against a lethal infection with a heterosubtypic virus strain in mice. Vaccine 2007; 25:612-20.
    • (2007) Vaccine , vol.25 , pp. 612-620
    • Kreijtz, J.H.1    Bodewes, R.2    van Amerongen, G.3    Kuiken, T.4    Fouchier, R.A.5    Osrerhaus, A.D.6    Rimmelzwaan, G.F.7
  • 63
    • 0036889420 scopus 로고    scopus 로고
    • Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell deficient mice
    • Belz GT, Wodarz D, Diaz G, Nowak MA, Doherry PC. Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell deficient mice. J Virol 2002; 76:12388-93.
    • (2002) J Virol , vol.76 , pp. 12388-12393
    • Belz, G.T.1    Wodarz, D.2    Diaz, G.3    Nowak, M.A.4    Doherry, P.C.5
  • 64
    • 0029811734 scopus 로고    scopus 로고
    • Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells
    • Cardin RD, Brooks JW, Sarawar SR, Doherty PC. Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells. J Exp Med 1996; 184:863-71.
    • (1996) J Exp Med , vol.184 , pp. 863-871
    • Cardin, R.D.1    Brooks, J.W.2    Sarawar, S.R.3    Doherty, P.C.4
  • 66
    • 0037154795 scopus 로고    scopus 로고
    • Supplementation of conventional trivalent influenza vaccine with purified viral N1 and N2 neuraminidases induces a balanced immune response without antigenic competition
    • Johansson BE, Pokorny BA, Tiso VA. Supplementation of conventional trivalent influenza vaccine with purified viral N1 and N2 neuraminidases induces a balanced immune response without antigenic competition. Vaccine 2002; 20:1670-4.
    • (2002) Vaccine , vol.20 , pp. 1670-1674
    • Johansson, B.E.1    Pokorny, B.A.2    Tiso, V.A.3
  • 67
    • 0018965475 scopus 로고
    • Further studies of the neuraminidase content of inactivated influenza vaccines and the neuraminidase antibody responses after vaccination of immunologically primed and unprimed populations
    • Kendal AP, Bozeman FM, Ennis FA. Further studies of the neuraminidase content of inactivated influenza vaccines and the neuraminidase antibody responses after vaccination of immunologically primed and unprimed populations. Infect Immun 1980; 29:966-71.
    • (1980) Infect Immun , vol.29 , pp. 966-971
    • Kendal, A.P.1    Bozeman, F.M.2    Ennis, F.A.3
  • 68
    • 0021828035 scopus 로고
    • Antigenic determinants of influenza virus haemagglu-tinin. X. A comparison of the physical and antigenic properties of monomeric and trimeric forms
    • Nestorowicz A, Laver G, Jackson DC. Antigenic determinants of influenza virus haemagglu-tinin. X. A comparison of the physical and antigenic properties of monomeric and trimeric forms. J Gen Virol 1985; 66:1687-95.
    • (1985) J Gen Virol , vol.66 , pp. 1687-1695
    • Nestorowicz, A.1    Laver, G.2    Jackson, D.C.3
  • 69
    • 0040881580 scopus 로고
    • Anti-Influenza Response Achieved by Immunization with a synthetic conjugate
    • Muller, GM., Shapira, M and Arnon, R. Anti-Influenza Response Achieved by Immunization with a synthetic conjugate. PNAS 1982; 79:569-73
    • (1982) PNAS , vol.79 , pp. 569-573
    • Muller, G.M.1    Shapira, M.2    Arnon, R.3
  • 70
    • 0021909830 scopus 로고
    • Antibodies elicited by influenza virus hemagglutinin fail to bind to synthetic peptides representing putative antigenic sites
    • Nestorowicz A, Tregear GW, Southwell CN, Martyn J, Murray JM, White DO, Jackson DC. Antibodies elicited by influenza virus hemagglutinin fail to bind to synthetic peptides representing putative antigenic sites. Mol Immunol 1985; 22:145-54.
    • (1985) Mol Immunol , vol.22 , pp. 145-154
    • Nestorowicz, A.1    Tregear, G.W.2    Southwell, C.N.3    Martyn, J.4    Murray, J.M.5    White, D.O.6    Jackson, D.C.7
  • 72
    • 0018016213 scopus 로고
    • Antigenic glycopeptides HA1 and HA2 of influenza virus hemagglutinin. II. Reactivity with rabbit sera against intact virus and purified undissociated hemagglutinin
    • Russ G, Styk B, Polakova K. Antigenic glycopeptides HA1 and HA2 of influenza virus hemagglutinin. II. Reactivity with rabbit sera against intact virus and purified undissociated hemagglutinin. Acta Virol 1978; 22:371-82.
    • (1978) Acta Virol , vol.22 , pp. 371-382
    • Russ, G.1    Styk, B.2    Polakova, K.3
  • 73
    • 0020626189 scopus 로고
    • Preparation of influenza virus subviral particles lacking the FIA1 subunit of hemagglutinin: Unmasking of cross-reactive HA2 determinants
    • Graves PN, Schulman JL, Young JF, Palese P. Preparation of influenza virus subviral particles lacking the FIA1 subunit of hemagglutinin: unmasking of cross-reactive HA2 determinants. Virology 1983; 126:106-16
    • (1983) Virology , vol.126 , pp. 106-116
    • Graves, P.N.1    Schulman, J.L.2    Young, J.F.3    Palese, P.4
  • 74
    • 0020633096 scopus 로고
    • Structure of the catalytic and antigenic sites in influenza virus neuraminidase
    • Varghese JN, Laver, WG and Colman PM. Structure of the catalytic and antigenic sites in influenza virus neuraminidase. Nature 1983; 303:35-40.
    • (1983) Nature , vol.303 , pp. 35-40
    • Varghese, J.N.1    Laver, W.G.2    Colman, P.M.3
  • 75
    • 0020633096 scopus 로고
    • Structure of the catalytic and antigenic sires in influenza virus neuraminidase
    • Colman PM, Varghese JN, Laver WG. Structure of the catalytic and antigenic sires in influenza virus neuraminidase. Nature 1983; 303:41-44.
    • (1983) Nature , vol.303 , pp. 41-44
    • Colman, P.M.1    Varghese, J.N.2    Laver, W.G.3
  • 76
    • 0017670185 scopus 로고
    • Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
    • Biddison WE, Doherry PC, Webster RG. Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses. J Exp Med 1977; 146:690-7.
    • (1977) J Exp Med , vol.146 , pp. 690-697
    • Biddison, W.E.1    Doherry, P.C.2    Webster, R.G.3
  • 77
    • 0022517321 scopus 로고
    • Spin-labeling of influenza virus hemagglutinin permits analysis of the conformational change at low pH and its inhibition by antibody
    • Yoden S, Kida H, Kuwabara M, Yanagawa R, Webster RG. Spin-labeling of influenza virus hemagglutinin permits analysis of the conformational change at low pH and its inhibition by antibody. Virus Res 1986; 3:251-61.
    • (1986) Virus Res , vol.3 , pp. 251-261
    • Yoden, S.1    Kida, H.2    Kuwabara, M.3    Yanagawa, R.4    Webster, R.G.5
  • 78
    • 0010463633 scopus 로고
    • Inhibition of viral neuraminidase as a new approach to the prevention of influenza
    • Ed. Pollard, M, New York, Academic Press
    • Kilbourne ED, Palese P, Schulman JL. Inhibition of viral neuraminidase as a new approach to the prevention of influenza. In Perspectives in virology Vol 9 (Ed. Pollard, M.) New York, Academic Press, 1975; 99-113
    • (1975) Perspectives in virology , vol.9 , pp. 99-113
    • Kilbourne, E.D.1    Palese, P.2    Schulman, J.L.3
  • 79
    • 0018894311 scopus 로고
    • Antigenic variation of influenza A virus nucleoprotein detected with monoclonal antibodies
    • van Wyke KL, Hinshaw VS, Bean WJ Jr, Webster RG. Antigenic variation of influenza A virus nucleoprotein detected with monoclonal antibodies. J Virol 1980; 35:24-30.
    • (1980) J Virol , vol.35 , pp. 24-30
    • van Wyke, K.L.1    Hinshaw, V.S.2    Bean Jr, W.J.3    Webster, R.G.4
  • 80
    • 0030296823 scopus 로고    scopus 로고
    • Dissociation of influenza virus neuraminidase from matrix and nulceoprotein eliminates cognate help and antigenic competition
    • Johansson BE, Kilbourne ED. Dissociation of influenza virus neuraminidase from matrix and nulceoprotein eliminates cognate help and antigenic competition. Virology 1996; 225:136-44.
    • (1996) Virology , vol.225 , pp. 136-144
    • Johansson, B.E.1    Kilbourne, E.D.2
  • 81
    • 0028276709 scopus 로고    scopus 로고
    • Lawson C, Bennink J, Restifo N, Yewdell J, Murphy BR. Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challenge. 1994; J Virol 68:3505.
    • Lawson C, Bennink J, Restifo N, Yewdell J, Murphy BR. Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challenge. 1994; J Virol 68:3505.
  • 84
    • 0017540885 scopus 로고
    • Immunologic recognition of influenza virus-infected cells. I. Generation of a virus-strain specific and a cross-reactive subpopulation of cytotoxic T cells in the response to type A influenza viruses of different subtypes
    • Braciale TJ. Immunologic recognition of influenza virus-infected cells. I. Generation of a virus-strain specific and a cross-reactive subpopulation of cytotoxic T cells in the response to type A influenza viruses of different subtypes. Cell Immunol 1977; 33:423-36.
    • (1977) Cell Immunol , vol.33 , pp. 423-436
    • Braciale, T.J.1
  • 85
    • 0022995943 scopus 로고
    • Cell-mediated immune responses to influenza virus antigens expressed by vaccinia virus recombinants
    • Andrew ME, Coupar BE, Ada GL, Boyle DB. Cell-mediated immune responses to influenza virus antigens expressed by vaccinia virus recombinants. Microb Pathog 1986; 1:443-52.
    • (1986) Microb Pathog , vol.1 , pp. 443-452
    • Andrew, M.E.1    Coupar, B.E.2    Ada, G.L.3    Boyle, D.B.4
  • 86
    • 0019507483 scopus 로고
    • Heterogeneity and specificity of cloned lines of influenza-virus specific cytotoxic T lymphocytes
    • Braciale TJ, Andrew ME, Braciale VL. Heterogeneity and specificity of cloned lines of influenza-virus specific cytotoxic T lymphocytes. J Exp Med 1981; 153:910-23
    • (1981) J Exp Med , vol.153 , pp. 910-923
    • Braciale, T.J.1    Andrew, M.E.2    Braciale, V.L.3
  • 87
    • 0022483534 scopus 로고
    • The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides
    • Townsend, ARM, Rothbard J. Gotch FM, Bahadur G, Wraith D, and McMichal AJ. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 1986; 44:959-68.
    • (1986) Cell , vol.44 , pp. 959-968
    • Townsend, A.R.M.1    Rothbard, J.2    Gotch, F.M.3    Bahadur, G.4    Wraith, D.5    McMichal, A.J.6
  • 88
    • 0033809634 scopus 로고    scopus 로고
    • Diminished primary and secondary influenza virus-specific CD8(+) T-cell responses in CD4-depleted Ig(-/-) mice
    • Riberdy JM, Christensen JP, Branum K, Doherty PC. Diminished primary and secondary influenza virus-specific CD8(+) T-cell responses in CD4-depleted Ig(-/-) mice. J Virol 2000; 74:9762-5.
    • (2000) J Virol , vol.74 , pp. 9762-9765
    • Riberdy, J.M.1    Christensen, J.P.2    Branum, K.3    Doherty, P.C.4
  • 89
    • 0035658084 scopus 로고    scopus 로고
    • A novel influenza A virus mitochondrial protein that induces cell death
    • Chen W, Calvo PA, Malide D, Gibbs J, Schubert U, Bacik I, et al. A novel influenza A virus mitochondrial protein that induces cell death. Nat Med 2001; 7:1306-12.
    • (2001) Nat Med , vol.7 , pp. 1306-1312
    • Chen, W.1    Calvo, P.A.2    Malide, D.3    Gibbs, J.4    Schubert, U.5    Bacik, I.6
  • 93
    • 6044253358 scopus 로고    scopus 로고
    • Powell TJ, Brown DM, Hollenbaugh JA, Charbonneau T, Kemp RA, Swain SL, Dutton RW CD8+ T cells responding to influenza infection reach and persist at higher numbers than CD4+ T cells independently of precursor frequency. Clin Immunol 2004; 113:89-100.
    • Powell TJ, Brown DM, Hollenbaugh JA, Charbonneau T, Kemp RA, Swain SL, Dutton RW CD8+ T cells responding to influenza infection reach and persist at higher numbers than CD4+ T cells independently of precursor frequency. Clin Immunol 2004; 113:89-100.
  • 94
    • 33744942931 scopus 로고    scopus 로고
    • Host range restriction and pathogenicity in the context of influenza pandemic
    • Neuman G, KawaokaY. Host range restriction and pathogenicity in the context of influenza pandemic. Emerging Infectious Diseases 2006; 12: 881-6.
    • (2006) Emerging Infectious Diseases , vol.12 , pp. 881-886
    • Neuman, G.1    KawaokaY2
  • 95
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
    • Walter E A, Greenberg PD, Gilberr MJ, Finch RJ, Watanabe KS, Thomas ED, Riddell SR. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl J Med 1995; 333: 1038-44.
    • (1995) N Engl J Med , vol.333 , pp. 1038-1044
    • Walter, E.A.1    Greenberg, P.D.2    Gilberr, M.J.3    Finch, R.J.4    Watanabe, K.S.5    Thomas, E.D.6    Riddell, S.R.7
  • 96
    • 0028865505 scopus 로고
    • Human CD4+ T-cell repertoire of responses to influenza A virus hemagglutinin after recent natural infection
    • Gelder CM, Welsh KI, Faith A, Lamb JR, Askonas BA. Human CD4+ T-cell repertoire of responses to influenza A virus hemagglutinin after recent natural infection. J Virol 1995; 69:7497-506.
    • (1995) J Virol , vol.69 , pp. 7497-7506
    • Gelder, C.M.1    Welsh, K.I.2    Faith, A.3    Lamb, J.R.4    Askonas, B.A.5
  • 97
    • 0022353964 scopus 로고
    • A synthetic decapeptide of influenza virus hemagglutinin elicits helper T cells with the same fine recognition specificities as occur in response to whole virus
    • Hackett CJ, Hurwitz JL, Dietzschold B, Gerhard W A synthetic decapeptide of influenza virus hemagglutinin elicits helper T cells with the same fine recognition specificities as occur in response to whole virus. J Immunol 1985; 135:1391-4.
    • (1985) J Immunol , vol.135 , pp. 1391-1394
    • Hackett, C.J.1    Hurwitz, J.L.2    Dietzschold, B.3    Gerhard, W.4
  • 98
    • 0020075108 scopus 로고
    • Antigen-specific human T lymphocyte clones: Viral antigen specificity of influenza virus-immune clones
    • Lamb JR, Eckels DD, Phelan M, Lake P, Woody JN. Antigen-specific human T lymphocyte clones: viral antigen specificity of influenza virus-immune clones. J Immunol 1982; 128:1428-32
    • (1982) J Immunol , vol.128 , pp. 1428-1432
    • Lamb, J.R.1    Eckels, D.D.2    Phelan, M.3    Lake, P.4    Woody, J.N.5
  • 99
    • 0021894285 scopus 로고
    • Murine TH response to influenza virus: Recognition of hemagglutinin, neuraminidase, matrix, and nucleoproteins
    • Hurwitz JL, Hackett CJ, McAndrew EC, Gerhard W Murine TH response to influenza virus: recognition of hemagglutinin, neuraminidase, matrix, and nucleoproteins. J Immunol 1985; 134:1994-8.
    • (1985) J Immunol , vol.134 , pp. 1994-1998
    • Hurwitz, J.L.1    Hackett, C.J.2    McAndrew, E.C.3    Gerhard, W.4
  • 100
    • 0021961454 scopus 로고
    • Recognition of influenza virus hemagglutinin by subtype-specific and cross-reactive proliferative T cells: Contribution of HA1 and HA2 polypeptide chains
    • Katz JM, Laver WG, White DO, and Anders, EM. Recognition of influenza virus hemagglutinin by subtype-specific and cross-reactive proliferative T cells: contribution of HA1 and HA2 polypeptide chains. J Immunol 1985; 134:616-22.
    • (1985) J Immunol , vol.134 , pp. 616-622
    • Katz, J.M.1    Laver, W.G.2    White, D.O.3    Anders, E.M.4
  • 101
    • 0021645783 scopus 로고
    • Characterization of the murine TH response to influenza virus hemagglurinin: Evidence for three major specificities
    • Hurwitz JL, Herber-Katz E, Hackett CJ, Gerhard W. Characterization of the murine TH response to influenza virus hemagglurinin: evidence for three major specificities. J Immunol 1984; 133:3371-7.
    • (1984) J Immunol , vol.133 , pp. 3371-3377
    • Hurwitz, J.L.1    Herber-Katz, E.2    Hackett, C.J.3    Gerhard, W.4
  • 102
    • 0023735364 scopus 로고
    • Differential ability of B cells specific for external vs. internal influenza virus proteins to respond to help from influenza virus-specific T-cell clones in vivo
    • Scherle PA, Gerhard W. Differential ability of B cells specific for external vs. internal influenza virus proteins to respond to help from influenza virus-specific T-cell clones in vivo. PNAS USA 1988; 85:4446-50.
    • (1988) PNAS USA , vol.85 , pp. 4446-4450
    • Scherle, P.A.1    Gerhard, W.2
  • 103
    • 0023546371 scopus 로고
    • Antigen-presenting B cells and helper T cells cooperatively mediate intravirionic antigenic competition between influenza A virus surface glycoproteins
    • Johansson BE, Moran TM, Kilbourne ED. Antigen-presenting B cells and helper T cells cooperatively mediate intravirionic antigenic competition between influenza A virus surface glycoproteins. PNAS USA 1987; 84:6869-73.
    • (1987) PNAS USA , vol.84 , pp. 6869-6873
    • Johansson, B.E.1    Moran, T.M.2    Kilbourne, E.D.3
  • 104
    • 0016294555 scopus 로고
    • Antibody responses to antigenic determinants of influenza virus hemagglutinin. Thymus dependence of antibody formation and thymus independence of immunological memory
    • Virelizier JL, Postlethwaite R, Schild GC, Allison AC. Antibody responses to antigenic determinants of influenza virus hemagglutinin. Thymus dependence of antibody formation and thymus independence of immunological memory. J Exp Med 1974; 140:1559-70.
    • (1974) J Exp Med , vol.140 , pp. 1559-1570
    • Virelizier, J.L.1    Postlethwaite, R.2    Schild, G.C.3    Allison, A.C.4
  • 105
    • 0026462441 scopus 로고
    • Immunogenicity of free synthetic peptides corresponding to T helper epitopes of the influenza HA 1 subunit. Induction of virus cross reacting CD4+ T lymphocytes in mice
    • Schneider C, Van Regenmortel MH. Immunogenicity of free synthetic peptides corresponding to T helper epitopes of the influenza HA 1 subunit. Induction of virus cross reacting CD4+ T lymphocytes in mice. Arch Virol 1992; 125:103-19.
    • (1992) Arch Virol , vol.125 , pp. 103-119
    • Schneider, C.1    Van Regenmortel, M.H.2
  • 106
    • 0033392612 scopus 로고    scopus 로고
    • MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen
    • Novak EJ, Liu AW, Nepom GT, Kwok WW. MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen. J Clin Invest 1999; 104:R63-7.
    • (1999) J Clin Invest , vol.104
    • Novak, E.J.1    Liu, A.W.2    Nepom, G.T.3    Kwok, W.W.4
  • 107
    • 0042834284 scopus 로고    scopus 로고
    • HLA class II-restricted CD4+ T cell responses directed against influenzaviral antigens postinfluenza vaccination
    • Danke NA, Kwok WW HLA class II-restricted CD4+ T cell responses directed against influenzaviral antigens postinfluenza vaccination. J Immunol 2003; 171:3163-9.
    • (2003) J Immunol , vol.171 , pp. 3163-3169
    • Danke, N.A.1    Kwok, W.W.2
  • 110
    • 84984537291 scopus 로고
    • Serological Response to Intranasal Administration of Inactive Influenza Virus in Children
    • Quilligan JJ, Francis T. Serological Response to Intranasal Administration of Inactive Influenza Virus in Children. J Clin Invest 1947; 26:1079-87.
    • (1947) J Clin Invest , vol.26 , pp. 1079-1087
    • Quilligan, J.J.1    Francis, T.2
  • 111
    • 29744438219 scopus 로고    scopus 로고
    • Epstein SL. Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: an experiment of nature. J Infect Dis 2006; 193:49-53.
    • Epstein SL. Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: an experiment of nature. J Infect Dis 2006; 193:49-53.
  • 112
    • 0021926908 scopus 로고
    • Cross-subtype protection in humans during sequential overlapping and/or concurrent epidemics caused by H3N2 and H1N1 influenza viruses
    • Sonoguchi T, Naito H, Hara M, Takeuchi Y, Fukumi H. Cross-subtype protection in humans during sequential overlapping and/or concurrent epidemics caused by H3N2 and H1N1 influenza viruses. J Infect Dis 1985; 151:81-8.
    • (1985) J Infect Dis , vol.151 , pp. 81-88
    • Sonoguchi, T.1    Naito, H.2    Hara, M.3    Takeuchi, Y.4    Fukumi, H.5
  • 113
    • 0032589509 scopus 로고    scopus 로고
    • Marshall D, Sealy R, Sangster M, Coleclough C. TH Cells Primed During Influenza Virus Infection Provide Help for Qualitatively Distinct Antibody Responses to Subsequent Immunizationl The Journal of Immunology 1999; 163:4673-4682.
    • Marshall D, Sealy R, Sangster M, Coleclough C. TH Cells Primed During Influenza Virus Infection Provide Help for Qualitatively Distinct Antibody Responses to Subsequent Immunizationl The Journal of Immunology 1999; 163:4673-4682.
  • 114
    • 0035124035 scopus 로고    scopus 로고
    • Cross-reactive, cell-mediated immunity and protection of chickens from lethal H5N1 influenza virus infection in Hong Kong poultry markets
    • Seo SH, Webster RG. Cross-reactive, cell-mediated immunity and protection of chickens from lethal H5N1 influenza virus infection in Hong Kong poultry markets. J Virol 2001; 75:2516-25.
    • (2001) J Virol , vol.75 , pp. 2516-2525
    • Seo, S.H.1    Webster, R.G.2
  • 115
    • 0033761607 scopus 로고    scopus 로고
    • Heterologous protection against lethal A/HongKong/156/97 (H5N1) influenza virus infection in C57BL/6 mice
    • O'Neill E, Krauss SL, Riberdy JM, Webster RG, Woodland DL. Heterologous protection against lethal A/HongKong/156/97 (H5N1) influenza virus infection in C57BL/6 mice. J Gen Virol 2000; 81:2689-96
    • (2000) J Gen Virol , vol.81 , pp. 2689-2696
    • O'Neill, E.1    Krauss, S.L.2    Riberdy, J.M.3    Webster, R.G.4    Woodland, D.L.5
  • 116
    • 0019494587 scopus 로고
    • In vitro antibody response to influenza virus. Specificity of helper T cell recognizing hemagglutinin
    • Anders EM, Katz JM, Jackson DC, White DO. In vitro antibody response to influenza virus. Specificity of helper T cell recognizing hemagglutinin. J Immunol 1981; 127:669-72.
    • (1981) J Immunol , vol.127 , pp. 669-672
    • Anders, E.M.1    Katz, J.M.2    Jackson, D.C.3    White, D.O.4
  • 118
    • 0030890660 scopus 로고    scopus 로고
    • An interactive web site providing MHC ligand predictions: Application to HIV research. AIDS Res and Hum
    • De Groot AS, Jesdale BM, Szu E, Schafer JR. An interactive web site providing MHC ligand predictions: application to HIV research. AIDS Res and Hum Retroviruses 1997; 13:539-41.
    • (1997) Retroviruses , vol.13 , pp. 539-541
    • De Groot, A.S.1    Jesdale, B.M.2    Szu, E.3    Schafer, J.R.4
  • 119
    • 0032210911 scopus 로고    scopus 로고
    • Prediction of well-conserved HIV-1 ligands using a Matrix-based Algorithm, EpiMatrix
    • Schafer JA, Jesdale BM, George JA, Kouttab NM, De Groot AS. Prediction of well-conserved HIV-1 ligands using a Matrix-based Algorithm, EpiMatrix. Vaccine 1998; 16:1880-4.
    • (1998) Vaccine , vol.16 , pp. 1880-1884
    • Schafer, J.A.1    Jesdale, B.M.2    George, J.A.3    Kouttab, N.M.4    De Groot, A.S.5
  • 126
    • 0018615087 scopus 로고
    • Reinfection with influenza A (H3N2) virus in young children and their families
    • Frank AL, Taber LH, Glezen WP, Paredes A, Couch RB. Reinfection with influenza A (H3N2) virus in young children and their families. J Inf Disease 1979; 140: 829-36.
    • (1979) J Inf Disease , vol.140 , pp. 829-836
    • Frank, A.L.1    Taber, L.H.2    Glezen, W.P.3    Paredes, A.4    Couch, R.B.5
  • 127
    • 0030044652 scopus 로고    scopus 로고
    • Synthetic recombinant influenza vaccine induces efficient long-term immunity and cross-strain protection
    • Levi R, Arnon R. Synthetic recombinant influenza vaccine induces efficient long-term immunity and cross-strain protection. Vaccine 1996; 14:85-92.
    • (1996) Vaccine , vol.14 , pp. 85-92
    • Levi, R.1    Arnon, R.2
  • 128
    • 0037150741 scopus 로고    scopus 로고
    • Intranasal immunization with synthetic recombinant vaccine containing multiple epitopes of influenza virus
    • Jeon SH, Ben-Yedidia T, Arnon R. Intranasal immunization with synthetic recombinant vaccine containing multiple epitopes of influenza virus. Vaccine 2002; 20:2772-80.
    • (2002) Vaccine , vol.20 , pp. 2772-2780
    • Jeon, S.H.1    Ben-Yedidia, T.2    Arnon, R.3
  • 129
    • 0034936071 scopus 로고    scopus 로고
    • Synthesis of linear and comb-like peptide constructs containing up to four copies of a T cell epitope and their capacity to stimulate T cells
    • Mack J, Falk K, Rotzschke O, Walk T, Strominger JL, Jung G. Synthesis of linear and comb-like peptide constructs containing up to four copies of a T cell epitope and their capacity to stimulate T cells. J Pept Sci 2001; 7:338-45.
    • (2001) J Pept Sci , vol.7 , pp. 338-345
    • Mack, J.1    Falk, K.2    Rotzschke, O.3    Walk, T.4    Strominger, J.L.5    Jung, G.6
  • 132
    • 45849112018 scopus 로고    scopus 로고
    • Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV
    • In Press
    • Rivera DS, McMurry JA, Buus S, Martin W, De Groot AS. Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV. Vaccine 2007; In Press.
    • (2007) Vaccine
    • Rivera, D.S.1    McMurry, J.A.2    Buus, S.3    Martin, W.4    De Groot, A.S.5


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