Dynamics of oxygen delivery and consumption during evoked neural stimulation using a compartment model and CBF and tissue PO2 measurements

NeuroImage

Volumn 42, Issue 1, 2008, Pages 49-59

  Vazquez, Alberto L ^a   Masamoto, Kazuto ^b   Kim, Seong Gi ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Brain; CBF; CMRO2; fMRI; Microcirculation; Oxygen Delivery; Oxygen transport

Indexed keywords

ISOFLURANE; NITROPRUSSIDE SODIUM; NITROUS OXIDE; OXYGEN; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD VESSEL PERMEABILITY; BRAIN BLOOD FLOW; BRAIN METABOLISM; BRAIN OXYGEN CONSUMPTION; CONTROLLED STUDY; ELECTROSTIMULATION; LASER DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; NONHUMAN; OXYGEN TRANSPORT; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX; VASODILATATION;

ANIMALS; CEREBROVASCULAR CIRCULATION; COMPUTER SIMULATION; EVOKED POTENTIALS, SOMATOSENSORY; MALE; MODELS, NEUROLOGICAL; OXYGEN; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSENSORY CORTEX;

EID: 45849125371     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2008.04.024     Document Type: Article

References (27)

1. 2 during functional activation using oxygen phosphorescence quenching. J. Cereb. Blood Flow Metab,. 21 5 (2001) 511-516
2. Arbit E., and DiResta G.R. Application of laser Doppler flowmetry in neurosurgery. Neurosurg. Clin. N. Am. 7 4 (1996) 741-748
3. Buxton R.B., and Frank L.R. A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation. J. Cereb. Blood Flow Metab. 17 1 (1997) 64-72
4. Davis T.L., Kwong K.K., Weisskoff R.M., and Rosen B.R. Calibrated functional MRI: mapping the dynamics of oxidative metabolism. Proc. Natl. Acad. Sci. U. S. A. 95 4 (1998) 1834-1839
5. Fatt I. The polarographic oxygen sensor: Its theory of operation and its application in biology, medicine, and technology (1976), CRC Press
6. Fox P.T., Raichle M.E., Mintun M.A., and Dence C. Nonoxidative glucose consumption during focal physiologic neural activity. Science 241 4864 (1988) 462-464
7. Fukuda M., Wang P., Moon C.H., Tanifuji M., and Kim S.G. Spatial specificity of the enhanced dip inherently induced by prolonged oxygen consumption in cat visual cortex: implication for columnar resolution functional MRI. Neuroimage 30 1 (2006) 70-87
8. Gray L.H., and Steadman J.M. Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood. J. Physiol. 175 (1964) 161-171
9. Hoge R.D., Atkinson J., Gill B., Crelier G.R., Marrett S., and Pike G.B. Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex. Proc. Natl. Acad. Sci. U. S. A. 96 16 (1999) 9403-9408
10. Huppert T.J., Allen M.S., Benav H., Jones P.B., and Boas D.A. A multicompartment vascular model for inferring baseline and functional changes in cerebral oxygen metabolism and arterial dilation. J. Cereb. Blood Flow Metab. 27 6 (2007) 1262-1279
11. Kassissia I.G., Goresky C.A., Rose C.P., Schwab A.J., Simard A., Huet P.M., et al. Tracer oxygen distribution is barrier-limited in the cerebral microcirculation. Circ. Res. 77 6 (1995) 1201-1211
12. Kim S.G., Rostrup E., Larsson H.B., Ogawa S., and Paulson O.B. Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation. Magn. Reson. Med. 41 6 (1999) 1152-1161
13. Kim T., Hendrich K.S., Masamoto K., and Kim S.G. Arterial versus total blood volume changes during neural activity-induced cerebral blood flow change: implication for BOLD fMRI. J. Cereb. Blood Flow Metab. 27 6 (2007) 1235-1247
14. Liu C.Y., Eskin S.G., and Hellums J.D. The oxygen permeability of cultured endothelial cell monolayers. Adv. Exp. Med. Biol. 345 (1994) 723-730
15. Masamoto K., Omura T., Takizawa N., Kobayashi H., Katura T., Maki A., et al. Biphasic changes in tissue partial pressure of oxygen closely related to localized neural activity in guinea pig auditory cortex. J. Cereb. Blood Flow Metab. 23 9 (2003) 1075-1084
16. Masamoto K., Kim T., Fukuda M., Wang P., and Kim S.G. Relationship between neural, vascular, and BOLD signals in isoflurane-anesthetized rat somatosensory cortex. Cereb. Cortex. 17 4 (2007) 942-950
17. Masamoto K., Vazquez A., Wang P., and Kim S.G. Trial-by-trial relationship between neural activity, oxygen consumption, and blood flow responses. Neuroimage 40 2 (2008) 442-450
18. Nagaoka T., Zhao F., Wang P., Harel N., Kennan R.P., Ogawa S., et al. Increases in oxygen consumption without cerebral blood volume change during visual stimulation under hypotension condition. J. Cereb. Blood. Flow. Metab. 26 8 (2006) 1043-1051
19. Peppiatt C.M., Howarth C., Mobbs P., and Attwell D. Bidirectional control of CNS capillary diameter by pericytes. Nature 443 12 (2006) 700-704
20. Popel A.S. Theory of oxygen transport to tissue. Crit. Rev. Biomed. Eng. 17 3 (1989) 257-321
21. Shulman R.G., Hyder F., and Rothman D.L. Lactate efflux and the neuroenergetic basis of brain function. NMR Biomed. 14 7-8 (2001) 389-396
22. Thompson J.K., Peterson M.R., and Freeman R.D. Single-neuron activity and tissue oxygenation in the cerebral cortex. Science 299 5609 (2003) 1070-1072
23. Valabregue R., Aubert A., Burger J., Bittoun J., and Costalat R. Relation between cerebral blood flow and metabolism explained by a model of oxygen exchange. J. Cereb. Blood Flow Metab. 23 5 (2003) 536-545
24. Vovenko E. Distribution of oxygen tension on the surface of arterioles, capillaries and venules of brain cortex and in tissue in normoxia: an experimental study on rats. Pflugers Arch. 437 4 (1999) 617-623
25. Weiss H.R., Buchweitz E., and Sinha A.K. Effect of hypoxic-hypocapnia on cerebral regional oxygen consumption and supply. Microvasc. Res. 25 2 (1983) 194-204
26. Wu D.M., Kawamura H., Sakagami K., Kobayashi M., and Puro D.G. Cholinergic regulation of pericyte-containing retinal microvessels. Am. J. Physiol., Heart Circ. Physiol. 284 (2003) H2083-H2090
27. Zheng Y., Martindale J., Johnston D., Jones M., Berwick J., and Mayhew J. A model of the hemodynamic response and oxygen delivery to brain. Neuroimage 16 3 Pt 1 (2002) 617-637