Antioxidant activity of melatonin on fatty liver induced by ethionine in mice;Actividad antioxidante de la melatonina sobre el hígado graso inducido por etionina en ratones

Archivos de Medicina Veterinaria

Volumn 40, Issue 1, 2008, Pages 51-57

  Ferraro, S M ^a   Lopez Ortega A ^a,b  

^a UNIVERSIDAD CENTROCCIDENTAL LISANDRO ALVARADO   (Venezuela)

^b NONE   (Venezuela)

Author keywords

Fatty liver; Melatonin; Mice; Oxidative stress

Indexed keywords

MUS;

EID: 45849122153     PISSN: 0301732X     EISSN: 07176201     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Aarsaether N, R Berge, A Husoy, A Aarsland, H Kryvi, A Svardal, P Ueland, M Farstad. 1988. Ethionine-induced alterations of enzymes involved in lipid metabolism and their possible relationship to induction of fatty liver. Biochim Biophys Acta 963, 349-358.
2. Alpers D, K Isselbacher. 1975. Fatty liver: biochemical and clinical aspects. In: Shiff L (ed). Diseases of the liver. Lipincott Company Philadelphia, USA, Pp 815-832.
3. Antunes F, LR Barclay, K Ingold, M King, J Norris, J Scaiano, F Xi. 1999. On the antioxidant activity of melatonin. Free Radic Biol Med 26, 117-128.
4. Baydas G, M Gursu, S Yilmaz, S Canpolat, A Yasar, G Cikim, H Canatan. 2002. Daily rhythm of glutathione peroxidase activity, lipid peroxidation and glutathione levels in tissues of pinealectomized rats. Neurosci Lett 323, 195-198.
5. Beyer CH, J Steketee, D Saphier. 1998. Antioxidant properties of melatonin-An emerging mystery. Biochem Pharmacol 56, 1265-1272.
6. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-254.
7. Bruck R, H Aeed, Y Avni, H Shirin, Z Matas, M Shahmurov, I Avinoach, G Zozulya, N Weizman, A Hochman. 2004. Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats. J Hepatol 40, 86-93.
8. Cabrer J, S Burkhardt, D Tan, L Manchester, M Karbownik, R Reiter. 2001. Autoxidation and toxicant-induced oxidation of lipid and DNA in monkey liver: reduction of molecular damage by melatonin. Pharmacol Toxicol 89, 225-230.
9. Daniels W, R Reiter, D Melchiorri, E Sewerinek, M Pablos, G Ortiz. 1995. Melatonin counteracts lipid peroxidation induced by carbon tetrachloride but does not restore glucose-6-phosphatase activity. J Pineal Res 19, 1-6.
10. Gitto, E, D Tan, R Reiter, M Karbownik, L Manchester, S Cuzzocrea, F Fulia, I Barberi. 2001. Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates. J Pharm Pharmacol 53, 1393-1401.
11. nd ed. In: Free Radicals in Biology and Medicine. Clarendon Press, Oxford, UK, Pp 11-14, 188-275.
12. Hautekeete, ML. 1995. Hepatotoxicity of antibiotics. Acta Gastroenterol Belg 58, 290-296.
13. Lieber C. 2001. Alcoholic liver injury: pathogenesis and therapy in 2001. Pathol Biol (Paris) 49, 738-752.
14. López-Ortega A, S Ferraro, C Mendoza, Y Márquez. 1997. Intervención de radicales libres en el hígado graso inducido por etionina. Memorias X Congreso Chileno de Química Clínica, Talca, Chile.
15. Mayo J, R Sainz, I Antoli, F Herrera, V Martin, C Rodriguez. 2002. Melatonin regulation of antioxidant enzyme gene expression. Cell Mol Life Sci 59, 1706-1713.
16. Melchiorri D, R Reiter, A Attia, M Hara, A Burgos, G Nistico. 1995. Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats. Life Sci 56, 83-89.
17. Melchiorri D, R Reiter, E Sewerynek, M Hara, L Chen, G Nistico, 1996. Paraquat toxicity and oxidative damage: Reduction by melatonin. Biochem Pharmacol 51, 1095-1099.
18. Menéndez-Peláez A, R Reiter. 1993. Distribution of melatonin in mammalian tissues: the relative importance of nuclear versus cytosolic localization. J Pineal Res 15, 59-69.
19. Naji L, A Carrillo-Vico, J Guerrero, J Calvo. 2004. Expression of membrane and nuclear melatonin receptors in mouse peripheral organs. Life Sci 74, 2227-2236.
20. Ohkawa H, N Ohishi, K Yagi. 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95, 351-358.
21. Ohta Y, M Kongo-Nishimura, T Matsura, K Yamada, A Kitagawa, T Kishikawa. 2004. Melatonin prevents disruption of hepatic reactive oxygen species metabolism in rats treated with carbon tetrachloride. J Pineal Res 36, 10-17.
22. Reiter R, D Tan, B Poeggeler, A Menendez-Pelaez, L Chen, S Saarela. 1994. Melatonin as a free radical scavenger: implications for aging and age related diseases. Ann N Y Acad Sci 719, 1-12.
23. Reiter R. 1995. Functional pleiotropy of the neurohormone melatonin: antioxidant protection and neuroendocrine regulation. Front Neuroendocrinol 16, 383-415.
24. Reiter R. 1996. Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals. Eur J Endocrinol 134, 412-420.
25. Ruiz M, A López-Ortega. 2000. Concentración de MDA en hígado graso inducido por una dosis alta de oxitetraciclina en ratones preñadas. Acta Cient Venez 51 (Supl. 2), 101.
26. Suzuki Y, H Forman, A Sevanian. 1997. Oxidants as stimulators of signal transduction. Free Radic Biol Med 22, 269-285.
27. Tan D, B Poeggeler, R Reiter, L Chen, S Chen, L Manchester, L Barlow. 1993. The pineal hormone melatonin inhibits DNA adduct formation induced by chemical carcinogen safrole in vivo. Cancer Lett 70, 65-71.
28. Tan D, R Reiter, L Chen, B Poeggeler, L Manchester, L Barlow. 1994. Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. Carcinogenesis 15, 215-218.
29. Trinder P. 1984. Enzymatics methods, Ann Clin Biochem 6, 24-27.
30. Turjanski A, R Rosenstein, D Estrin. 1998. Reactions of melatonin and related indoles with free radicals: a computational study. J Med Chem 41, 3684-3689.
31. Wallin B, B Rosengren, H Shertzer, G Camejo. 1993. Lipoprotein oxidation and measurement of thiobarbituric acid reacting substances formation in a single microtiter plate: Its use for evaluation of antioxidants. Anal Biochem 208, 10-15.
32. Wiesenberg I, M Missbach, C Calberg. 1998. The potential role of the transcription factor RZR/ROR as a mediator of nuclear melatonin signaling. Restor Neurol Neurosci 12, 143-150.
33. Winiarska K, T Fraczyk, D Malinska, J Drozak, J Bryla. 2006. Melatonin attenuates diabetes-induced oxidative stress in rabbits. J Pineal Res 40, 168-76.
34. Yokota F, Y Igarashi, R Suzue. 1982. Effects of ethionine feeding on fatty liver and plasma lipoprotein in rats. J Nutr 112, 405-409.