Autoxidation and toxicant-induced oxidation of lipid and DNA in monkey liver: Reduction of molecular damage by melatonin

Pharmacology and Toxicology

Volumn 89, Issue 5, 2001, Pages 225-230

  Cabrera, Javier ^a,b   Burkhardt, Susanne ^a   Tan, Dun Xian ^a   Manchester, Lucien C ^a   Karbownik, Malgorzata ^a   Reiter, Russel J ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETAL; ALKENE; CHROMIUM; DNA; FERROUS ION; HYDROGEN PEROXIDE; LIPID; MALONALDEHYDE; MELATONIN; TOXIC SUBSTANCE;

ADOLESCENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; AUTOOXIDATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; LIPID PEROXIDATION; LIVER HOMOGENATE; LIVER PROTECTION; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; CHLORIDES; CHROMIUM COMPOUNDS; DEOXYGUANOSINE; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FERROUS COMPOUNDS; FREE RADICAL SCAVENGERS; HAPLORHINI; HYDROGEN PEROXIDE; IRON; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; MELATONIN; OXIDATIVE STRESS;

ANIMALIA; PRIMATES; RODENTIA;

EID: 0035161021     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.2001.890502.x     Document Type: Article

References (4)

1. Abe, M., R. J. Reiter, P. H. Orhii, M. Hara, B. Poeggeler & L. R. Barlow-Walden: Inhibitory effect of melatonin on cataract formation in newborn rats: Evidence of an antioxidative role for melatonin. J. Pineal Res. 1994, 17, 94-100.
2. Al-Bayati, Z. A. F. & S. J. Stohs: The role of iron in 2,3 ,7, 8-tetra-chlorodibenzo-p-dioxin-induced lipid peroxidation by rat liver microsomes. Toxicol Lett. 1987, 38, 115-121.
3. Ames, B. N. & M.K. Shigenaga: Oxidants are major contributor to cancer and aging. In: DNA and free radicals. Eds.: B. Halliwell, O. I. Arouoma. Harwood, London, 1993, pp. 1-18.
4. Bradford, M.: A rapid and sensitive method for quantification of protein utilizing the principle of protein dye binding. Ann. Biochem. 1976, 71, 171-178.