Apoptotic death of renal tubular cells in experimental sepsis

Surgical Infections

Volumn 9, Issue 3, 2008, Pages 377-388

  Messaris, Evangelos ^a   Memos, Nikolaos ^a   Chatzigianni, Emmy ^a   Kataki, Agapi ^a   Nikolopoulou, Marilena ^a   Manouras, Andreas ^a   Albanopoulos, Konstadinos ^a   Konstadoulakis, Manousos M ^a   Bramis, John ^a  

^a HIPPOKRATION HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CYTOCHROME C; INTERLEUKIN 6; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL NUCLEUS; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; KIDNEY PARENCHYMA; KIDNEY TUBULE CELL; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SEPSIS; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 8; CYTOCHROMES C; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; KERATIN-18; KIDNEY TUBULES; MALE; MICROSCOPY, ELECTRON; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; SEPSIS; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 45749130176     PISSN: 10962964     EISSN: None     Source Type: Journal    
DOI: 10.1089/sur.2006.018     Document Type: Article

References (20)

1. Jacobi J. Pathophysiology of sepsis. Am J Health Syst Pharm 2002;15:S3-S8.
2. Silvester W, Bellomo R, Cole L. Epidemiology, management, and outcome of severe acute renal failure of critical illness in Australia. Crit Care Med 2001;29: 1910-1915.
3. van Lambalgen AA, van Kraats AA, van den Bos GC, et al. Renal function and metabolism during endotoxemia in rats: Role of hypoperfusion. Circ Shock 1991;35:164-173.
4. Brezis M, Rosen S. Hypoxia of the renal medulla: Its implications for disease. N Engl J Med 1995;332:647-655.
5. Ravikant T, Lucas TE. Renal blood flow distribution in septic hyperdynamic pigs. J Surg Res 1977;22:294-298.
6. Baud L, Oudinet JP, Bens M, et al. Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide. Kidney Int 1989;35: 1111-1118.
7. Cunningham PN, Dyanov HM, Park P, et al. Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. J Immunol 2002;168:5817-5823.
8. Jo SK, Cha DR, Cho WY, et al. Inflammatory cytokines and lipopolysaccharide induce Fas-mediated apoptosis in renal tubular cells. Nephron 2002; 91:406-415.
9. Bonegio R, Lieberthal W. Role of apoptosis in the pathogenesis of acute renal failure. Curr Opin Nephrol Hypertens 2002;11:301-308.
10. Liberthal W, Levine JS. Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury. Am J Physiol 1996;271:R477-R488.
11. Carr NJ. M30 expression demonstrates apoptotic cells, correlates with in situ end-labeling, and is associated with Ki-67 expression in large intestinal neoplasms. Arch Pathol Lab Med 2000;124:1768-1772.
12. Van Grieken NCT, Meijer GA, Hausen A, et al. Increased apoptosis in gastric mucosa adjacent to intestinal metaplasia. J Clin Pathol 2003;56:358-361.
13. Power C, Fanning N, Redmond HP. Cellular apoptosis and organ injury in sepsis: A review. Shock 2002;18:197-211.
14. Leers MP. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol 1999;187:567-572.
15. Messmer UK, Briner VA, Pfeilschifter J. Tumour necrosis factor-alpha and lipopolysaccharide induce apoptotic cell death in bovine glomerular endothelial cells. Kidney Int 1999;55:2322-2337.
16. Wan L, Bellomo R, Di Giantomasso D, Ronco C. The pathogenesis of septic acute renal failure. Curr Opin Crit Care 2003;9:496-502.
17. Hengartner MO. The biochemistry of apoptosis. Nature 2000;407:770-776.
18. Du C, Guan Q, Yin Z, et al. IL-2-mediated apoptosis of kidney tubular epithelial cells is regulated by the caspase-8 inhibitor c-FLIP. Kidney Int 2005;67:1397-1409.
19. Du C, Guan Q, Yin Z, et al. Nitric oxide induces apoptosis in renal tubular epithelial cells through activation of caspase-8. Am J Physiol Renal Physiol 2006; 290:1044-1054.
20. Tsujimoto Y. Cell death: Regulation by the Bcl-2 protein family. Psychogeriatrics 2006;6:64-70.