Stereoselective oxidation and glucuronidation of carvedilol in human liver and intestinal microsomes

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 6, 2008, Pages 1297-1300

  Ishida, Kazuya ^a   Taira, Shigehiro ^a   Morishita, Hiroki ^a   Kayano, Yuichiro ^a   Taguchi, Masato ^a   Hashimoto, Yukiya ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Carvedilol; Intestine; Liver; Stereoselective metabolism

Indexed keywords

CARVEDILOL; CYTOCHROME P450 1A2; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; FURAFYLLINE; KETOCONAZOLE; QUINIDINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; URIDINE DIPHOSPHATE GLUCURONIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DRUG CLEARANCE; GLUCURONIDATION; HUMAN; HUMAN CELL; INTESTINE; LIVER; MALE; MICROSOME; NONHUMAN; OXIDATION; RAT; STEREOCHEMISTRY;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CARBAZOLES; GLUCURONIDES; HUMANS; INTESTINES; MALE; MICROSOMES; MICROSOMES, LIVER; OXIDATION-REDUCTION; PROPANOLAMINES; RATS; RATS, WISTAR; STEREOISOMERISM;

EID: 45749110620     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1297     Document Type: Article

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