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Volumn 326, Issue 1, 2008, Pages 296-305

Impact of impurity on kinetic estimates from transport and inhibition studies

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; GLYCOCHOLIC ACID; TAUROLITHOCHOLIC ACID; URSODEOXYCHOLIC ACID;

EID: 45749100431     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.135863     Document Type: Article
Times cited : (7)

References (12)
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    • Balakrishnan A, Hussainzada N, Gonzalez P, Bermejo M, Swaan PW, and Polli JE (2007) Bias in estimation of transporter kinetic parameters from overexpression systems: interplay of transporter expression level and substrate affinity. J Pharmacol Exp Ther 320:133-144.
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    • Balakrishnan, A.1    Hussainzada, N.2    Gonzalez, P.3    Bermejo, M.4    Swaan, P.W.5    Polli, J.E.6
  • 2
    • 33745769730 scopus 로고    scopus 로고
    • Apical sodium dependent bile acid transporter (ASBT, SLC10A2): A potential prodrug target
    • Balakrishnan A and Polli JE (2006) Apical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug target. Mol Pharm 3:223-230.
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    • Balakrishnan, A.1    Polli, J.E.2
  • 3
    • 23844510921 scopus 로고    scopus 로고
    • Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT)
    • Balakrishnan A, Sussman DJ, and Polli JE (2005) Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT). Pharm Res 22:1269-1280.
    • (2005) Pharm Res , vol.22 , pp. 1269-1280
    • Balakrishnan, A.1    Sussman, D.J.2    Polli, J.E.3
  • 4
    • 33745799433 scopus 로고    scopus 로고
    • Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter
    • Balakrishnan A, Wring SA, Coop A, and Polli JE (2006a) Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter. Mol Pharm 3:282-292.
    • (2006) Mol Pharm , vol.3 , pp. 282-292
    • Balakrishnan, A.1    Wring, S.A.2    Coop, A.3    Polli, J.E.4
  • 5
    • 33745584351 scopus 로고    scopus 로고
    • Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): Influence of steroidal hydroxylation pattern and C-24 conjugation
    • Balakrishnan A, Wring SA, and Polli JE (2006b) Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation. Pharm Res 23:1451-1459.
    • (2006) Pharm Res , vol.23 , pp. 1451-1459
    • Balakrishnan, A.1    Wring, S.A.2    Polli, J.E.3
  • 6
    • 0036112603 scopus 로고    scopus 로고
    • Lipid modulation and liver function tests. A report of the Program on the Surgical Control of the Hyperlipidemias (POSCH)
    • Buchwald H, Williams SE, Matts JP, and Boen JR (2002) Lipid modulation and liver function tests. A report of the Program on the Surgical Control of the Hyperlipidemias (POSCH). J Cardiovasc Risk 9:83-87.
    • (2002) J Cardiovasc Risk , vol.9 , pp. 83-87
    • Buchwald, H.1    Williams, S.E.2    Matts, J.P.3    Boen, J.R.4
  • 8
    • 1242317691 scopus 로고    scopus 로고
    • The sodium bile salt cotransport family SLC10
    • Hagenbuch B and Dawson P (2004) The sodium bile salt cotransport family SLC10. Pflugers Arch 447:566-570.
    • (2004) Pflugers Arch , vol.447 , pp. 566-570
    • Hagenbuch, B.1    Dawson, P.2
  • 9
    • 0033611305 scopus 로고    scopus 로고
    • The continuing importance of bile acids in liver and intestinal disease
    • Hofmann AF (1999) The continuing importance of bile acids in liver and intestinal disease. Arch Intern Med 159:2647-2658.
    • (1999) Arch Intern Med , vol.159 , pp. 2647-2658
    • Hofmann, A.F.1
  • 11
    • 34548458522 scopus 로고    scopus 로고
    • Exploitation of bile acid transport systems in prodrug design
    • Sievänen E (2007) Exploitation of bile acid transport systems in prodrug design. Molecules 12:1859-1889.
    • (2007) Molecules , vol.12 , pp. 1859-1889
    • Sievänen, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.