Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: A role for ATP-sensitive potassium channels

Epilepsy and Behavior

Volumn 13, Issue 2, 2008, Pages 284-289

  Niaki, Seyed Esfandiar Akhavan ^a   Shafaroodi, Hamed ^b   Ghasemi, Mehdi ^c   Shakiba, Bijan ^a   Fakhimi, Ali ^c   Dehpour, Ahamd Reza ^c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acidosis; ATP sensitive potassium channels; Hypercapnia; Mice; Mouth breathing; Nasal obstruction; Pentylenetetrazole; Seizure threshold

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DIAZOXIDE; GLIBENCLAMIDE; PENTETRAZOLE;

ACID BASE BALANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PH; ARTICLE; BLOOD GAS; BLOOD SAMPLING; CARBON DIOXIDE TENSION; CONTROLLED STUDY; LIGATION; MALE; MOUSE; MOUTH BREATHING; NONHUMAN; NOSE OBSTRUCTION; PROTEIN FUNCTION; RESPIRATORY ACIDOSIS; SEIZURE; SEIZURE THRESHOLD; STATISTICAL SIGNIFICANCE;

ACID-BASE EQUILIBRIUM; ACIDOSIS, RESPIRATORY; ANIMALS; BRAIN; CARBON DIOXIDE; DIAZOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; GLYBURIDE; INJECTIONS, INTRAPERITONEAL; KATP CHANNELS; MALE; MICE; MICE, INBRED STRAINS; MOUTH BREATHING; NASAL OBSTRUCTION; PENTYLENETETRAZOLE; SEIZURES;

EID: 45649085754     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2008.04.013     Document Type: Article

References (58)

1. Harding R., Hooper S.B., and Wood G.A. Initiation of oral breathing in lambs in response to airway obstruction: mechanisms. J Appl Physiol 71 (1991) 1574-1580
2. Petruson B. The importance of improved nasal breathing: a review of the Nozovent nostril dilator. Acta Otolaryngol 127 (2007) 418-423
3. Song H.G., and Pae E.K. Changes in orofacial muscle activity in response to changes in respiratory resistance. Am J Orthod Dentofacial Orthop 119 (2001) 436-442
4. Wagaiyu E.G., and Ashley F.P. Mouth breathing, lip seal and upper lip coverage and their relationship with gingival inflammation in 11-14-year-old schoolchildren. J Clin Periodontol 18 (1991) 698-702
5. Kalogjera L., Pegan B., and Petric V. Compensatory mechanisms induced by high oropharyngeal airway resistance in rats. Acta Otolaryngol 111 (1991) 384-388
6. Zwillich C.W., Pickett C.K., Hansen F.N., and Weil J.V. Disturbed sleep and prolonged apnea during nasal obstruction in normal man. Am Rev Respir Dis 124 (1981) 158-160
7. Ogura J.H., and Harvey J.E. Nasopulmunary mechanics: experimental evidence of the influence of the upper airway upon the lower. Acta Otolaryngol 71 (1971) 123-132
8. Cook T.A., and Komron R.M. Statistical analysis of the alterations of blood gases produced by nasal packing. Laryngoscope 83 (1973) 1802-1809
9. Konno A., Togawa K., and Hoshino T. The effect of nasal obstruction in infancy and early childhood upon ventilation. Laryngoscope 90 (1980) 669-707
10. Cavo J.V., Awamoto S.K., Berlin B.P., Zollinger W., and Ogura J.H. Arterial blood gas changes following nasal packing in dogs. Laryngoscope 85 (1975) 2055-2068
11. Ramadan M.F. Experimental nasal obstruction and changes in the arterial blood gases. Clin Otolaryngol Allied Sci 8 (1983) 245-250
12. Erkan M., Erhan E., Saǧlam A., and Arslan S. Compensatory mechanisms in rats with nasal obstructions. Tokai J Exp Clin Med 19 (1994) 67-71
13. Niaki E.A., Nemati M., Mani A.R., Amanpour S., Amanlou M., Mazhar P., Mehr S.E., and Dehpour A.R. Enhancement of indomethacin-induced gastric damage by mouth breathing in rabbits. Pathophysiology 11 (2005) 197-199
14. Foerster O. Hyperventilations epilepsie. Dtsch Z Nervenheilk 83 (1924) 347-356
15. Lennox W.G., Gibbs F.A., and Gibbs E.L. Effect on the electroencephalogram of drugs and conditions which influence seizures. Arch Neurol Psychiatry 36 (1936) 1236-1245
16. Balestrino M., and Somjen G.G. Concentration of carbon dioxide, interstitial pH and synaptic transmission in hippocampal formation of the rat. J Physiol 396 (1988) 247-266
17. Brian Jr. J.E. Carbon dioxide and the cerebral circulation. Anesthesiology 88 (1998) 1365-1386
18. Mulkey D.K., Stornetta R.L., Weston M.C., Simmons J.R., Parker A., Bayliss D.A., et al. Respiratory control by ventral surface chemoreceptor neurons in rats. Nat Neurosci 7 (2004) 1360-1369
19. 2 to cortical excitability via pH. Neuron 48 (2005) 1011-1023
20. Guaranha M.S., Garzon E., Buchpiguel C.A., Tazima S., Yacubian E.M., and Sakamoto A.C. Hyperventilation revisited: physiological effects and efficacy on focal seizure activation in the era of video-EEG monitoring. Epilepsia 46 (2005) 69-75
21. Capps R.T. Carbon dioxide. Clin Anesth 3 (1968) 122-134
22. Chesler M. Regulation and modulation of pH in the brain. Physiol Rev 83 (2003) 1183-1221
23. Wright C.L., and Boulant J.A. Carbon dioxide and pH effects on temperature-sensitive and -insensitive hypothalamic neurons. J Appl Physiol 102 (2007) 1357-1366
24. Dusser De Barenne J.G., Marshall C.S., McCulloch W.S., and Nims L.F. Observations of the pH of arterial blood, the pH and electrical activity of the cerebral cortex. Am J Physiol 124 (1938) 631-636
25. 2 saturation in vivo. J Appl Physiol 16 (1961) 896-902
26. Siesjö B.K., Von Hanwehr R., Nergelius G., Nevander G., and Ingvar M. Extra- and intracellular pH in the brain during seizures and in the period following arrest of seizure activity. J Cereb Blood Flow Metab 5 (1985) 47-57
27. ATP channels. J Mol Cell Cardiol 38 (2005) 945-949
28. Faraci F.M., and Sobey C.G. Role of potassium channels in regulation of cerebral vascular tone. J Cereb Blood Flow Metab 18 (1998) 1047-1063
29. Opie L.H. Modulation of ischemia by regulation of the ATP-sensitive potassium channel. Cardiovasc Drugs Ther 7 (1993) 507-513
30. ATP channels in vascular smooth muscle. Clin Exp Pharmacol Physiol 29 (2002) 312-316
31. Rosenblum W.I. ATP-sensitive potassium channels in the cerebral circulation. Stroke 34 (2003) 1547-1552
32. ATP channel activity in dorsal vagal neurons of juvenile rats in situ during metabolic disturbances. Brain Res 1017 (2004) 137-145
33. + channels in skeletal muscle by intracellular protons. Nature 343 (1990) 375-377
34. Dietrich H.H., and Dacey Jr. R.G. Effects of extravascular acidification and extravascular alkalinization on constriction and depolarization in rat cerebral arterioles in vitro. J Neurosurg 81 (1994) 437-442
35. + homeostasis in the CSF. In: Siesjö B.K., and Sorensen S.C. (Eds). Ion homeostasis of the brain (1971), Munksgaard, Copenhagen 154-165
36. 2. In: Kessler M., Harrison D.K., and Hoper J. (Eds). Ion measurements in physiology and medicine (1985), Springer, Berlin 199-205
37. + channel, in the model of hippocampus-generating partial seizures in rats. Eur J Pharmacol 311 (1996) 37-44
38. Yamada K., Ji J.J., Yuan H., et al. Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science 292 (2001) 1543-1546
39. Shafaroodi H., Asadi S., Sadeghipour H., et al. Role of ATP-sensitive potassium channels in the biphasic effects of morphine on pentylenetetrazole-induced seizure threshold in mice. Epilepsy Res 75 (2007) 63-69
40. Soundarapandian M.M., Wu D., Zhong X., et al. Expression of functional Kir6.1 channels regulates glutamate release at CA3 synapses in generation of epileptic form of seizures. J Neurochem 103 (2007) 1982-1988
41. Shafaroodi H, Ghasemi M, Dehpour AR. Elevation of pentylenetetrazole-induced seizure threshold in cholestatic mice: interaction between opioid and cannabinoid systems. J Gastroenterol Hepatol. Published article online 2007; doi:10.1111/j.1440-1746.2007.05101.x.
42. Lund A.K., Agbor L.N., Zhang N., Baker A., Zhao H., Fink G.D., et al. Loss of the aryl hydrocarbon receptor induces hypoxemia, endothelin-1, and systemic hypertension at modest altitude. Hypertension 51 (2008) 803-809
43. Ruetten H., Southan G.J., Abate A., and Thiemermann C. Attenuation of endotoxin-induced multiple organ dysfunction by 1-amino-2-hydroxy-guanidine, a potent inhibitor of inducible nitric oxide synthase. Br J Pharmacol 118 (1996) 261-270
44. DeFinis M.L. Effetti della iperventilazione polmonare sulla attivitá della zona sensitivomotrice corticale del cane. Arch Fisiol 30 (1932) 494-499
45. Brody B.S., and Dusser De Barenne J.G.D. Effect of hyperventilation on the excitability of the motor cortex in cats. Arch Neurol Psychiatry 28 (1932) 571-578
46. Wirrell E.C., Camfield P.R., Gordon K.E., Camfield C.S., Dooley J.M., and Hanna B.D. Will a critical level of hyperventilation-induced hypocapnia always induce an absence seizure?. Epilepsia 37 (1996) 459-462
47. Bao Y., Jiang J., Zhu C., Lu Y., Cai R., and Ma C. Effect of hyperventilation on brain tissue oxygen pressure, carbon dioxide pressure, pH value and intracranial pressure during intracranial hypertension in pigs. Chin J Traumatol 3 (2000) 210-213
48. Datto C., Rai A.K., Ilivicky H.J., and Caroff S.N. Augmentation of seizure induction in electroconvulsive therapy: a clinical reappraisal. J ECT 18 (2002) 118-125
49. Kirstein L. Early effects of oxygen lack and carbon dioxide excess on spinal reflexes. Acta Physiol Scand 23 (1951) 1-54
50. Cohen M.J. Discharge pattern of brain stem respiratory neurons in relation to carbon dioxide tension. J Neurophysiol 31 (1968) 142-165
51. Carpenter D.O., Hubbard J.H., Humphrey D.R., Thompson H.K., and Marshall W. Carbon dioxide effects on nerve cell function. In: Nahas G., and Schaefer K.E. (Eds). Carbon dioxide and metabolic regulation (1974), Springer, New York 49-62
52. Yang L., Su J., Zhang X., and Jiang C. Hypercapnia modulates synaptic interaction of cultured brainstem neurons. Respir Physiol Neurobiol 160 (2008) 147-159
53. Waddell W.J., and Bates R.G. Intracellular pH. Physiol Rev 49 (1969) 285-329
54. + channel openers prevent epilepsy induced by the Bee Venom Peptid MCD. Eur J Pharmacol 159 (1989) 329-330
55. Mattia D., Nagao T., Rogawski M.A., and Avoli M. Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice. Neuropharmacology 33 (1994) 1515-1522
56. Chrabi A., and Horisberger J.D. Stimulation of epithelial sodium channel activity by the sulfonylurea glibenclamide. J Pharmacol Exp Ther 290 (1999) 341-347
57. Sobey C.G. Potassium channel function in vascular disease. Arterioscler Thromb Vasc Biol 21 (2001) 28-38
58. D'hahan N., Moreau C., Prost A.L., et al. Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP. Proc Natl Acad Sci USA 96 (1999) 12162-12167