Quantitative High-Throughput Cell-Based Assays for Inhibitors of ROCK Kinases

Methods in Enzymology

Volumn 439, Issue , 2008, Pages 491-500

  Garton, Andrew J ^a   Castaldo, Linda ^a   Pachter, Jonathan A ^a  

^a OSI PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; FASUDIL; H 1152; PROTEIN ANTIBODY; RHO ASSOCIATED COILED COIL CONTAINING KINASE 1; RHO ASSOCIATED COILED COIL CONTAINING KINASE 2; RHO ASSOCIATED COILED COIL CONTAINING KINASE INHIBITOR; RHO KINASE; RHO KINASE INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ENZYME INHIBITOR; MYOSIN LIGHT CHAIN PHOSPHATASE; PPP1R12A PROTEIN, HUMAN;

CELL ASSAY; CELL MIGRATION; CYTOLYSIS; CYTOSKELETON; DRUG EFFECT; DRUG POTENCY; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBSTRATE; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; MALE; MOLECULAR SIZE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ASSAY; REVIEW; SIGNAL TRANSDUCTION; ARTICLE; CELL LINE; DRUG ANTAGONISM; METABOLISM; METHODOLOGY; PANCREAS TUMOR;

CELL LINE; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MYOSIN-LIGHT-CHAIN PHOSPHATASE; PANCREATIC NEOPLASMS; RHO-ASSOCIATED KINASES; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 45549102923     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(07)00433-8     Document Type: Review

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