Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 22, 2008, Pages 7845-7850

  Gomes, Regis ^a,c   Teixeira, Clarissa ^a,c   Teixeira, Maria Jânia ^a   Oliveira, Fabiano ^a,c   Menezes, Maria José ^a   Silva, Claire ^a   De Oliveira, Camila I ^a   Miranda, Jose C ^a   Elnaiem, Dia Eldin ^c   Kamhawi, Shaden ^c   Valenzuela, Jesus G ^c   Brodskyn, Cláudia I ^a,b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Instituto de Investigação em Imunologia   (Brazil)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Antisaliva immunity; Leishmania; Sand fly saliva; Vector based vaccine

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; PLASMID DNA; PROTEIN LJL11; PROTEIN LJM11; PROTEIN LJM17; PROTEIN LJM19; SALIVA PROTEIN; TRANSFORMING GROWTH FACTOR BETA; INSECT PROTEIN; LEISHMANIA VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DISEASE COURSE; FATALITY; HAMSTER; IMMUNIZATION; INFECTION PREVENTION; INOCULATION; LEISHMANIA INFANTUM; LIVER; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE IMMUNITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PSYCHODIDAE; SALIVA; SKIN; SPLEEN; VISCERAL LEISHMANIASIS; ANIMAL; DISEASE CARRIER; DISEASE MODEL; GENETICS; HUMAN; IMMUNITY; IMMUNOLOGY; INSECT BITE; METABOLISM; PARASITOLOGY; PLASMID; VACCINATION;

ARTHROPODA; CRICETINAE; LEISHMANIA INFANTUM; LUTZOMYIA LONGIPALPIS; PHLEBOTOMINAE;

ANIMALS; CRICETINAE; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY; INSECT BITES AND STINGS; INSECT PROTEINS; INSECT VECTORS; INTERFERON TYPE II; LEISHMANIASIS VACCINES; LEISHMANIASIS, VISCERAL; PLASMIDS; PSYCHODIDAE; SALIVARY PROTEINS; VACCINATION;

EID: 45549097643     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0712153105     Document Type: Article

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