Sandfly maxadilan exacerbates infection with Leishmania major and vaccinating against it protects against L. major infection

Journal of Immunology

Volumn 167, Issue 9, 2001, Pages 5226-5230

  Morris, R V ^a   Shoemaker, C B ^a   David, J R ^a   Lanzaro, G C ^a   Titus, R G ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IMMUNOMODULATION; INFECTION PREVENTION; LEISHMANIA MAJOR; LEISHMANIASIS; MOUSE; NONHUMAN; PARASITE TRANSMISSION; PRIORITY JOURNAL; PSYCHODIDAE; SALIVA; VACCINATION;

EID: 0035500911     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.9.5226     Document Type: Article

References (37)

1. Blood and tissue protozoa of human beings
2. TH1 and TH2 cell antigen receptors in experimental leishmaniasis
3. Role of saliva in blood-feeding by arthropods
4. The immunomodulatory factors of bloodfeeding arthropod saliva
5. Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity
6. Phlebotomus papatasi sand fly salivary gland lysate downregulates a Th1, but upregulates a Th2, response in mice infected with Leishmania major
7. Development of a natural model of cutaneous leishmaniasis: Powerful effects of vector saliva and saliva preexposure on the long term outcome of Leishmania major infection in the mouse ear dermis
8. Enhancement of virus transmission by tick salivary glands
9. Enhancement of tick-borne encephalitis virus transmission by tick salivary gland extracts
10. Mosquito feeding-induced enhancement of Cache Valley Virus (Bunyaviridae) infection in mice
11. A mouse model of Leishmania braziliensis braziliensis infection produced by co-injection with sand fly saliva
12. A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis
13. Maxadilan: Cloning and functional expression of the gene encoding this potent vasodilator peptide
14. Maxadilan, the vasodilator from sand flies, is a specific pituitary adenylate cyclase activating peptide type 1 receptor agonist
15. The vasoactive peptide Maxadilan from sand fly saliva inhibits TNF-α and induces IL-6 by mouse macrophages through interaction with the PACAP receptor
16. A simple method for quantifying Leishmania in tissues of infected animals
17. Variation in the salivary peptide, maxadilan, from species in the Lutzomyia longipalpis complex
18. T cell and non-T cell compartments can independently determine resistance to Leishmania major
19. Sand fly vector saliva selectively modulates macrophage functions that inhibit killing of Leishmania major and nitric oxide production
20. A method for the isolation and analysis of leucocytic cells from leishmanial ear lesions in mice
21. Analysis of the enhancing effect of sand fly saliva on infection with Leishmania in mice
22. Isolation of Maxadilan, a potent vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis
23. Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors in the brain
24. Receptors and transcriptional factors involved in the anti-inflammatory activity of VIP and PACAP
25. Pituitary adenylate cyclase-activating polypeptide and its receptors: From structure to functions
26. Vasoactive intestinal peptide (VIP)/pituitary adenylate cyclase-activating peptide receptor subtypes in mouse calvarial osteoblasts: Presence of VIP-2 receptors and differentiation-induced expression of VIP-1 receptors
27. Cytokines in parasitic diseases: The example of cutaneous leishmaniasis
28. Immunomodulatory properties of maxadilan, the vasodilator peptide from sand fly salivary gland extracts
29. Tick-host immunology: Significant advances and challenging opportunities
30. Prevention of Borrelia burgdorferi transmission in guinea pigs by tick immunity
31. Neutralization of Sindbus virus by antisera to antigens of vector mosquitoes
32. Sporozoite and normal salivary gland induced immunity in malaria
33. Plasmodium berghei: Sporozoite challenge, protection and hypersensitivity in mice
34. Protection against cutaneous leishmaniasis resulting from bites of uninfected sand flies
35. Leishmaniases of the New World: Current concepts and implications for future research
36. Saliva of Lutzomyia longipalpis sibling species differs in its composition and capacity to enhance leishmaniasis
37. Adenosine AMP, and protein phosphatase activity in sandfly saliva