Is peripheral locomotor muscle fatigue during endurance exercise a variable carefully regulated by a negative feedback system?

Journal of Physiology

Volumn 586, Issue 7, 2008, Pages 2027-2028

  Marcora, Samuele ^a  

^a BANGOR UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL NERVOUS SYSTEM; CYCLING; DYSPNEA; ENDURANCE; EXERCISE; EXERCISE INTENSITY; HOMEOSTASIS; HUMAN; LETTER; METABOLIC STRESS; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE FORCE; MUSCULOSKELETAL SYSTEM; MYALGIA; NEGATIVE FEEDBACK; PERCEPTION; PRIORITY JOURNAL; ENDURANCE TRAINING; EXERCISE PHYSIOLOGY; EXERCISE TOLERANCE; EXHAUSTION; MUSCLE INJURY; MUSCLE STRENGTH; NEUROMODULATION; SIGNAL TRANSDUCTION; ELECTROMYOGRAPHY; FEEDBACK SYSTEM; INNERVATION; LOCOMOTION; NOTE; PATHOPHYSIOLOGY; PHYSIOLOGY; SKELETAL MUSCLE;

CENTRAL NERVOUS SYSTEM; ELECTROMYOGRAPHY; FEEDBACK, BIOCHEMICAL; HOMEOSTASIS; HUMANS; LOCOMOTION; MUSCLE FATIGUE; MUSCLE, SKELETAL; PHYSICAL ENDURANCE;

EID: 45549096423     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2008.152470     Document Type: Letter

References (21)

1. Altenburg TM, Degens H, Van Mechelen W, Sargeant AJ & De Haan A (2007). Recruitment of single muscle fibers during submaximal cycling exercise. J Appl Physiol 103, 1752-1756.
2. Amann M & Calbet JA (2007). Convective oxygen transport and fatigue. J Appl Physiol.
3. Amann M & Dempsey JA (2007). Peripheral muscle fatigue from hyperoxia to moderate hypoxia - a carefully regulated variable? Physiology News 66, 28-29. http://www.physoc.org/publications
4. Amann M & Dempsey JA (2008). Locomotor muscle fatigue modifies central motor drive in healthy humans and imposes a limitation to exercise performance. J Physiol 586, 161-173.
5. Amann M, Hopkins WG & Marcora SM (2008). Similar sensitivity of time to exhaustion and time trial time to changes in endurance. Med Sci Sports Exerc 40, 574-578.
6. Borg GA (1998). Borg's Perceived Exertion and Pain Scales. Human Kinetics, Champaign, IL, USA.
7. Carlson NR (2004). Physiology of Behavior. Allyn and Bacon, Boston, MA, USA.
8. Cook DB (2006). Physical activity and pain. In Psychobiology of Physical Activity, ed. Acevedo EO & Ekkekakis P, pp. 203-217. Human Kinetics, Champaign, IL, USA.
9. Denton DA (2006). The Primordial Emotions: The Dawning of Consciousness. Oxford University Press, Oxford.
10. Gandevia SC (2001). Spinal and supraspinal factors in human muscle fatigue. Physiol Rev 81, 1725-1789.
11. Greig CA, Sargeant AJ & Vollestad NK (1985). Muscle force and fibre recruitment during dynamic exercise in man. J Physiol 371, 176 P.
12. Jones NL & Killian KJ (2000). Exercise limitation in health and disease. N Engl J Med 343, 632-641.
13. Kjaer M, Hanel B, Worm L, Perko G, Lewis SF, Sahlin K, Galbo H & Secher NH (1999). Cardiovascular and neuroendocrine responses to exercise in hypoxia during impaired neural feedback from muscle. Am J Physiol Regul Integr Comp Physiol 277, R76-R85.
14. Lucia A, Hoyos J & Chicharro JL (2001). Preferred pedalling cadence in professional cycling. Med Sci Sports Exerc 33, 1361-1366.
15. Marcora SM, Bosio A & De Morree HM (2008). Locomotor muscle fatigue increases cardiorespiratory responses and reduces performance during intense cycling exercise independently from metabolic stress. Am J Physiol Regul Integr Comp Physiol.
16. Noakes TD & Marino FE (2007). Arterial oxygenation, central motor output and exercise performance in humans. J Physiol 585, 919-921.
17. Presland JD, Dowson MN & Cairns SP (2005). Changes of motor drive, cortical arousal and perceived exertion following prolonged cycling to exhaustion. Eur J Appl Physiol 95, 42-51.
18. Sargeant AJ (2007). Structural and functional determinants of human muscle power. Exp Physiol 92, 323-331.
19. Smith SA, Querry RG, Fadel PJ, Gallagher KM, Stromstad M, Ide K, Raven PB & Secher NH (2003). Partial blockade of skeletal muscle somatosensory afferents attenuates baroreflex resetting during exercise in humans. J Physiol 551, 1013-1021.
20. Taylor JL & Gandevia SC (2007). A comparison of central aspects of fatigue in submaximal and maximal voluntary contractions. J Appl Physiol.
21. Woods SC & Ramsay DS (2007). Homeostasis: Beyond Curt Richter. Appetite 49, 388-398.