Association of serotonin transporter promoter regulatory region polymorphism and cerebral activity to visual presentation of food

Clinical Physiology and Functional Imaging

Volumn 28, Issue 4, 2008, Pages 270-276

  Kaurijoki, Salla ^a   Kuikka, Jyrki T ^b   Niskanen, Eini ^a   Carlson, Synnöve ^c,f   Pietiläinen, Kirsi H ^c,d   Pesonen, Ullamari ^d   Kaprio, Jaakko M ^c,d   Rissanen, Aila ^e   Tiihonen, Jari ^a   Karhunen, Leila ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^f TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Brain; Functional magnetic resonance imaging; Genotype; Overeating; Posterior cingulate cortex; Statistical parametric mapping

Indexed keywords

DNA; SEROTONIN TRANSPORTER;

ADULT; ALLELE; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CINGULATE GYRUS; CONTROLLED STUDY; FEMALE; FOOD; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION; VISUAL STIMULATION;

ADULT; ALLELES; ANALYSIS OF VARIANCE; APPETITE; BRAIN MAPPING; FEMALE; FOOD; GYRUS CINGULI; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); REGRESSION ANALYSIS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; VISUAL PERCEPTION;

EID: 45549096346     PISSN: 14750961     EISSN: 1475097X     Source Type: Journal    
DOI: 10.1111/j.1475-097X.2008.00804.x     Document Type: Article

References (36)

1. Bellgowan PS, Saad ZS, Bandettini PA. Understanding neural system dynamics through task modulation and measurement of functional MRI amplitude, latency, and width. Proc Natl Acad Sci USA (2003); 100: 1415-1419.
2. Birn RM, Cox RW, Bandettini PA. Detection versus estimation in event-related fMRI: Choosing the optimal stimulus timing. Neuroimage (2002); 15: 252-264.
3. Blundell JE. Is there a role for serotonin (5-hydroxytryptamine) in feeding? Int J Obes (1977); 1: 15-42.
4. Blundell JE. Serotonin manipulations and the structure of feeding behaviour. Appetite (1986); 7: 39-56.
5. Bookheimer SY, Strojwas MH, Cohen MS, Saunders AM, Pericak-Vance MA, Mazziotta JC, Small GW. Patterns of brain activation in people at risk for Alzheimer's disease. N Engl J Med (2000); 343: 450-456.
6. Brewerton TD, Jimerson DC. Studies of serotonin function in anorexia nervosa. Psychiatry Res (1996); 62: 31-42.
7. Bucholz KK, Cadoret R, Clonigner CR, Dinwiddlie SH, Hesselbrock VM, Nurnberger JI, Reich T, Schmidt I, Schuckit MA. A new, semi-structured psychiatric interview for use in genetic linkage studies: A report on the reliability of the SSAGA. J Stud Alcohol (1994); 55: 149-158.
8. Del Parigi A, Chen K, Salbe AD, Gautier JF, Ravussin E, Reiman EM, Tataranni PA. Tasting a liquid meal after a prolonged fast is associated with preferential activation of the left hemisphere. Neuroreport (2002); 13: 1141-1145.
9. Del Parigi A, Chen K, Salbe AD, Hill JO, Wing RR, Reiman EM, Tataranni PA. Persistence of abnormal neural responses to meal in postobese individuals. Int J Obes Relat Metab Disord (2004); 28: 370-377.
10. Friston KJ, Zarahn E, Josephs O, Henson RN, Dale AM. Stochastic designs in event-related fMRI. Neuroimage (1999); 10: 607-619.
11. Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage (2002); 15: 870-878.
12. Halford JC, Harrold JA, Boyland EJ, Lawton CL, Blundel JE. Serotonergic drugs: Effects on appetite expression and use for the treatment of obesity. Drugs (2007); 67: 27-55.
13. Hariri AR, Weinberger DR. Functional neuroimaging of genetic variation in serotonergic neurotransmission. Genes Brain Behav (2003); 2: 341-349.
14. Hariri AR, Mattay VS, Tessitore A, Kolachana B, Fera F, Goldman D, Egan MF, Weinberger DR. Serotonin transporter genetic variation and the response of the human amygdale. Science (2002); 297: 400-403.
15. He Y, Wang L, Zang Y, Tian L, Zhang X, Li K, Jiang T. Regional coherence changes in the early stages of Alzheimer's disease: A combined structural and resting-state functional MRI study. Neuroimage (2007); 35: 488-500.
16. Heils A, Teufel A, Petri S, Stöber G, Riederer P, Bengel D, Lesch KP. Allelic variation of human serotonin gene expression. J Neurochem (1996); 66: 2621-2624.
17. Hoffman JB, Kaplan JR, Kinkead B, Berga SL, Wilson ME. Metabolic and reproductive consequences of the serotonin transporter promoter polymorphism (5-HTTLPR) in adult female rhesus monkeys (Macaca mulatta). Endocrine (2007); 31: 202-211.
18. Kaprio J, Pulkkinen L, Rose RJ. Genetic and environmental factors in health-related behaviors: Studies on Finnish twins and twin families. Twin Res (2002); 5: 366-371.
19. Karhunen LJ, Vanninen EJ, Kuikka JT, Lappalainen RI, Tiihonen J, Uusitupa MI. Regional cerebral blood flow during exposure to food in obese binge eating women. Psychiatry Res (2001); 99: 29-42.
20. Kaye WH, Greeno CG, Moss H, Fernstrom J, Fernstrom M, Lilenfeld LR, Weltzin TE, Mann JJ. Alterations in serotonin activity and psychiatric symptoms after recovery from bulimia nervosa. Arch Gen Psychiatry (1998); 55: 927-935.
21. Killgore WE, Young AD, Femia LA, Bogorodzki P, Rogowska J, Yurgelun-Todd DA. Cortical and limbic activation during viewing of high- versus low-calorie foods. Neuroimage (2003); 19: 1381-1394.
22. Koskela AK, Kaurijoki S, Pietiläinen KH, Karhunen L, Pesonen U, Kuikka JT, Kaprio J, Rissanen A. Serotonin transporter binding and acquired obesity - an imaging study of monozygotic twin pairs. Physiol Behav (2008); 93: 724-732.
23. Lang PJ, Bradley MM, Cuthbert BN. International Affective Picture System (IAPS): Instruction Manual and Affective Ratings (2001). The Center for Research in Psychopathology, University of Florida, Gainesville, FL.
24. Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Müller CR, Hamer DH, Murphy DL. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science (1996); 274: 1527-1531.
25. Matsumoto R, Kitabayashi Y, Narumoto J, Wada Y, Okamoto A, Ushijima Y, Yokoyama C, Yamashita T, Takahashi H, Yasuno F, Suhara T, Fukui K. Regional cerebral blood flow changes associated with interoceptive awareness in the recovery process of anorexia nervosa. Prog Neuropsychopharmacol Biol Psychiatry (2006); 30: 1265-1270.
26. Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF, Kolachana B, Callicott JH, Weinberger DR. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci USA (2003); 100: 6186-6191.
27. Mosconi L, Sorbi S, de Leon MJ, Li Y, Nacmias B, Myoung PS, Tsui W, Ginestroni A, Bessi V, Fayyazz M, Caffarra P, Pupi A. Hypometabolism exceeds atrophy in presymptomatic early-onset familiar Alzheimer's disease. J Nucl Med (2006); 47: 1778-1786.
28. Murphy DL, Lerner A, Rudnick G, Lesch KP. Serotonin transporter: Genetic disorders, and pharmacogenetics. Mol Interv (2004); 4: 109-123.
29. Pellerin L, Magistretti PJ. Food for thought: Challenging the dogmas. J Cereb Blood Flow Metab (2003); 23: 1282-1286.
30. Porubska K, Veit R, Preissl H, Fritche A, Birbaumer N. Subjective feeling of appetite modulates brain activity: An fMRI study. Neuroimage (2006); 32: 1273-1280.
31. Rothemund Y, Preuschhof C, Bohner G, Bauknecht HC, Klingebiel R, Flor H, Klapp BF. Differential activation of the dorsal striatum by high-calorie visual food stimuli in obese individuals. Neuroimage (2007); 37: 410-421.
32. Small DM, Zatorre RJ, Dagher A, Evans AC, Jones-Gotman M. Changes in brain activity related to eating chocolate: From pleasure to aversion. Brain (2001); 124: 1720-1733.
33. Small DM, Gitelman DR, Gregory MD, Nobre AC, Parrish TB, Mesulam MM. The posterior cingulate and medial prefrontal cortex mediate the anticipatory allocation of spatial attention. Neuroimage (2003); 18: 633-641.
34. Szabo Z, Owonikoko T, Peyrot M, Varga J, Mathews WB, Ravert HT, Dannals RF, Wand G. Positron emission tomography imaging of the serotonin transporter in subjects with a history of alcoholism. Biol Psychiatry (2004); 55: 766-771.
35. Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain (1988). Georg Thieme Verlag, Stuttgart, New York.
36. Varnäs K, Halldin C, Hall H. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Hum Brain Mapp (2004); 22: 246-260.