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Volumn 36, Issue 2, 2008, Pages 129-140

Testing potential developmental toxicants with a cytotoxicity assay based on human embryonic stem cells

Author keywords

Alternative methods; Cytotoxicity; Embryotoxicity; Human embryonic stem cells; Inter species differences; Retinoids

Indexed keywords

ADENOSINE TRIPHOSPHATE; BASIC FIBROBLAST GROWTH FACTOR; DIMETHYL SULFOXIDE; FLUOROURACIL; ISOTRETINOIN; RESAZURIN; RETINOIC ACID; SACCHARIN; VALPROIC ACID;

EID: 45549093674     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290803600204     Document Type: Article
Times cited : (25)

References (31)
  • 1
    • 0004210529 scopus 로고    scopus 로고
    • 750pp. Sunderland, MA, USA: Sinauer Associates, Inc
    • Gilbert, S.F. (2003). Developmental Biology, 750pp. Sunderland, MA, USA: Sinauer Associates, Inc.
    • (2003) Developmental Biology
    • Gilbert, S.F.1
  • 2
    • 0034757851 scopus 로고    scopus 로고
    • Teratogenicity of isotretinoin revisited: Species variation and the role of all-trans-retinoic acid
    • Nau, H. (2001). Teratogenicity of isotretinoin revisited: species variation and the role of all-trans-retinoic acid. Journal of the American Academy of Dermatology 45, S183-187.
    • (2001) Journal of the American Academy of Dermatology , vol.45
    • Nau, H.1
  • 3
    • 8744223170 scopus 로고    scopus 로고
    • Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests
    • Genschow, E., Spielmann, H., Scholz, G., Pohl, I., Seiler, A., Clemann, N., Bremer, S. & Becker, K. (2004). Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests. ATLA 32, 209-244.
    • (2004) ATLA , vol.32 , pp. 209-244
    • Genschow, E.1    Spielmann, H.2    Scholz, G.3    Pohl, I.4    Seiler, A.5    Clemann, N.6    Bremer, S.7    Becker, K.8
  • 4
    • 0037401126 scopus 로고    scopus 로고
    • Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food-producing animals
    • Hurtt, M.E., Cappon, G.D. & Browning, A. (2003). Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food-producing animals. Food & Chemical Toxicology 41, 611-619.
    • (2003) Food & Chemical Toxicology , vol.41 , pp. 611-619
    • Hurtt, M.E.1    Cappon, G.D.2    Browning, A.3
  • 5
    • 22944481525 scopus 로고    scopus 로고
    • A novel role for Gab2 in bFGF-mediated cell survival during retinoic acidinduced neuronal differentiation
    • Mao, Y. & Lee, A.W. (2005). A novel role for Gab2 in bFGF-mediated cell survival during retinoic acidinduced neuronal differentiation. The Journal of Cell Biology 170, 305-316.
    • (2005) The Journal of Cell Biology , vol.170 , pp. 305-316
    • Mao, Y.1    Lee, A.W.2
  • 7
    • 0023176860 scopus 로고
    • Teratology Society position paper: Recommendations for Vitamin A use during pregnancy
    • Anon
    • Anon. (1987). Teratology Society position paper: recommendations for Vitamin A use during pregnancy. Teratology 2, 269-275.
    • (1987) Teratology , vol.2 , pp. 269-275
  • 8
    • 0009842982 scopus 로고    scopus 로고
    • Teratogenicity of retinoids in rodents, primates and humans
    • Hendrickx, A.G. (1998). Teratogenicity of retinoids in rodents, primates and humans. The Journal of Toxicological Sciences 23, 272.
    • (1998) The Journal of Toxicological Sciences , vol.23 , pp. 272
    • Hendrickx, A.G.1
  • 10
    • 45549103956 scopus 로고
    • Observations on the histopathogenesis of 5-fluorouracil developmental toxicity in New Zealand white rabbits and its amelioration by TTI, a functional analog of one carbon metabolism
    • De Sesso, J.M., Scialli, A.R. & Goeringer, G.L. (1995). Observations on the histopathogenesis of 5-fluorouracil developmental toxicity in New Zealand white rabbits and its amelioration by TTI, a functional analog of one carbon metabolism. Teratology 51, 172.
    • (1995) Teratology , vol.51 , pp. 172
    • De Sesso, J.M.1    Scialli, A.R.2    Goeringer, G.L.3
  • 12
  • 14
    • 0036097575 scopus 로고    scopus 로고
    • Selection of test chemicals for the ECVAM international validation study on in vitro embryotoxicity tests
    • Brown, N.A. (2002). Selection of test chemicals for the ECVAM international validation study on in vitro embryotoxicity tests. ATLA 30, 177-198.
    • (2002) ATLA , vol.30 , pp. 177-198
    • Brown, N.A.1
  • 15
    • 0003131638 scopus 로고
    • Sensitive stages for the production of developmental abnormalities in mice with 5-fluorouracil
    • Dagg, C.P. (1960). Sensitive stages for the production of developmental abnormalities in mice with 5-fluorouracil. American Journal of Anatomy 106, 89-96.
    • (1960) American Journal of Anatomy , vol.106 , pp. 89-96
    • Dagg, C.P.1
  • 16
    • 45549109622 scopus 로고    scopus 로고
    • Notice of Filing of Pesticide Petitions. US Environmental Protection Agency (EPA)
    • Anon
    • Anon. (1997). Notice of Filing of Pesticide Petitions. US Environmental Protection Agency (EPA). Federal Register 62, 34,261-34,271.
    • (1997) Federal Register , vol.62
  • 17
    • 0027635817 scopus 로고
    • Assessment of the effectiveness of animal developmental toxicity testing for human safety
    • Newman, L.M., Johnson, E.M. & Staples, R.E. (1993). Assessment of the effectiveness of animal developmental toxicity testing for human safety. Reproductive Toxicology 7, 359-390.
    • (1993) Reproductive Toxicology , vol.7 , pp. 359-390
    • Newman, L.M.1    Johnson, E.M.2    Staples, R.E.3
  • 19
    • 0026365921 scopus 로고
    • Cytotoxicity test using blastocyst-derived euploid embryonal stem cells: A new approach to in vitro teratogenesis screening
    • Laschinski, G., Vogel, R. & Spielmann, H. (1991). Cytotoxicity test using blastocyst-derived euploid embryonal stem cells: a new approach to in vitro teratogenesis screening. Reproductive Toxicology 5, 57-64.
    • (1991) Reproductive Toxicology , vol.5 , pp. 57-64
    • Laschinski, G.1    Vogel, R.2    Spielmann, H.3
  • 20
    • 18844406449 scopus 로고    scopus 로고
    • The detection of differentiation-inducing chemicals by using green fluorescent protein expression in genetically engineered terato-carcinoma cells
    • Adler, S., Paparella, M., Pellizzer, C., Hartung, T. & Bremer, S. (2005). The detection of differentiation-inducing chemicals by using green fluorescent protein expression in genetically engineered terato-carcinoma cells. ATLA 33, 91-103.
    • (2005) ATLA , vol.33 , pp. 91-103
    • Adler, S.1    Paparella, M.2    Pellizzer, C.3    Hartung, T.4    Bremer, S.5
  • 21
    • 34047240758 scopus 로고    scopus 로고
    • All-trans-retinoic acid and 13-cis-retinoic acid: Pharmacokinetics and biological activity in different cell culture models of human keratinocytes
    • Schroeder, M. & Zouboulis, C.C. (2007). All-trans-retinoic acid and 13-cis-retinoic acid: Pharmacokinetics and biological activity in different cell culture models of human keratinocytes. Hormone & Metabolic Research 39, 136-140.
    • (2007) Hormone & Metabolic Research , vol.39 , pp. 136-140
    • Schroeder, M.1    Zouboulis, C.C.2
  • 22
    • 0037226984 scopus 로고    scopus 로고
    • Retinoid target gene activation during induced tumor cell differentiation: Human embryonal carcinoma as a model
    • Spinella, M.J., Kerley, J.S., White, K.A. & Curtin, J.C. (2003). Retinoid target gene activation during induced tumor cell differentiation: human embryonal carcinoma as a model. The Journal of Nutrition 133, 273S-276S.
    • (2003) The Journal of Nutrition , vol.133
    • Spinella, M.J.1    Kerley, J.S.2    White, K.A.3    Curtin, J.C.4
  • 27
    • 0033870445 scopus 로고    scopus 로고
    • 13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors
    • Tsukada, M., Schröder, M., Roos, T.C., Chandraratna, R.A., Reichert, U., Merk, H.F., Orfanos, C.E. & Zouboulis, C.C. (2000). 13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors. The Journal of Investigative Dermatology 115, 321-327.
    • (2000) The Journal of Investigative Dermatology , vol.115 , pp. 321-327
    • Tsukada, M.1    Schröder, M.2    Roos, T.C.3    Chandraratna, R.A.4    Reichert, U.5    Merk, H.F.6    Orfanos, C.E.7    Zouboulis, C.C.8
  • 28
    • 28144456841 scopus 로고    scopus 로고
    • Mode of action: Inhibition of histone deacetylase, altering Wnt-dependent gene expression, and regulation of beta-catenin- developmental effects of valproic acid
    • Wiltse, J. (2005). Mode of action: inhibition of histone deacetylase, altering Wnt-dependent gene expression, and regulation of beta-catenin- developmental effects of valproic acid. Critical Reviews in Toxicology 35, 727-738.
    • (2005) Critical Reviews in Toxicology , vol.35 , pp. 727-738
    • Wiltse, J.1
  • 29
  • 30
    • 4344562814 scopus 로고    scopus 로고
    • The use of embryonic stem cells for regulatory developmental toxicity testing in vitro - the current status of test development
    • Bremer, S. & Hartung, T. (2004). The use of embryonic stem cells for regulatory developmental toxicity testing in vitro - the current status of test development. Current Pharmaceutical Design 10, 2733-2747.
    • (2004) Current Pharmaceutical Design , vol.10 , pp. 2733-2747
    • Bremer, S.1    Hartung, T.2
  • 31


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.