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Volumn 84, Issue 1, 2008, Pages 170-174

Simulated drug administration: An emerging tool for teaching clinical pharmacology during anesthesiology training

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; INTRAVENOUS ANESTHETIC AGENT; MUSCLE RELAXANT AGENT; OPIATE; PROPOFOL;

EID: 45549089137     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2008.76     Document Type: Review
Times cited : (32)

References (33)
  • 1
    • 33645647458 scopus 로고    scopus 로고
    • The well-being model: A new drug interaction model for positive and negative effects
    • Zanderigo, E. et al. The well-being model: a new drug interaction model for positive and negative effects. Anesthesiology 104, 742-753 (2006).
    • (2006) Anesthesiology , vol.104 , pp. 742-753
    • Zanderigo, E.1
  • 3
    • 0018394195 scopus 로고
    • Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine
    • Sheiner, L.B., Stanski, D.R., Vozeh, S., Miller, R.D. & Ham, J. Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin. Pharmacol. Ther. 25, 358-371 (1979).
    • (1979) Clin. Pharmacol. Ther , vol.25 , pp. 358-371
    • Sheiner, L.B.1    Stanski, D.R.2    Vozeh, S.3    Miller, R.D.4    Ham, J.5
  • 4
    • 0041843832 scopus 로고    scopus 로고
    • Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics
    • Minto, C.F., Schnider, T.W., Gregg, K.M., Henthorn, T.K. & Shafer, S.L. Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics. Anesthesiology 99, 324-333 (2003).
    • (2003) Anesthesiology , vol.99 , pp. 324-333
    • Minto, C.F.1    Schnider, T.W.2    Gregg, K.M.3    Henthorn, T.K.4    Shafer, S.L.5
  • 5
    • 0035693563 scopus 로고    scopus 로고
    • Utilisation of pharmacokinetic- pharmacodynamic modelling and simulation in regulatory decision-making
    • Gobburu, J.V. & Marroum, P.J. Utilisation of pharmacokinetic- pharmacodynamic modelling and simulation in regulatory decision-making. Clin. Pharmacokinet. 40, 883-892 (2001).
    • (2001) Clin. Pharmacokinet , vol.40 , pp. 883-892
    • Gobburu, J.V.1    Marroum, P.J.2
  • 6
    • 1442350321 scopus 로고    scopus 로고
    • Let's make better use of simulator time
    • Tullo, F. Let's make better use of simulator time. Aviat. Week Space Technol. 151, 66 (1999).
    • (1999) Aviat. Week Space Technol , vol.151 , pp. 66
    • Tullo, F.1
  • 8
    • 34447094136 scopus 로고    scopus 로고
    • Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans: 2. BIS and tetanic stimulus-induced withdrawal reflex
    • Mourisse, J., Lerou, J., Struys, M., Zwarts, M. & Booij, L. Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans: 2. BIS and tetanic stimulus-induced withdrawal reflex. Br. J. Anaesth. 98, 746-755 (2007).
    • (2007) Br. J. Anaesth , vol.98 , pp. 746-755
    • Mourisse, J.1    Lerou, J.2    Struys, M.3    Zwarts, M.4    Booij, L.5
  • 9
    • 34447093666 scopus 로고    scopus 로고
    • Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans: 1. BIS and blink reflex
    • Mourisse, J., Lerou, J., Struys, M., Zwarts, M. & Booij, L. Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans: 1. BIS and blink reflex. Br. J. Anaesth. 98, 737-745 (2007).
    • (2007) Br. J. Anaesth , vol.98 , pp. 737-745
    • Mourisse, J.1    Lerou, J.2    Struys, M.3    Zwarts, M.4    Booij, L.5
  • 10
    • 33745713031 scopus 로고    scopus 로고
    • Depth of anaesthesia monitoring: What's available, what's validated and what's next?
    • Bruhn, J., Myles, P.S., Sneyd, R. & Struys, M.M. Depth of anaesthesia monitoring: what's available, what's validated and what's next? Br. J. Anaesth. 97, 85-94 (2006).
    • (2006) Br. J. Anaesth , vol.97 , pp. 85-94
    • Bruhn, J.1    Myles, P.S.2    Sneyd, R.3    Struys, M.M.4
  • 11
    • 33244498054 scopus 로고    scopus 로고
    • Stimulation induced variability of pulse plethysmography does not discriminate responsiveness to intubation
    • Luginbühl, M., Rüfenacht, M., Korhonen, I., Gils, M., Jakob, S. & Petersen-Felix, S. Stimulation induced variability of pulse plethysmography does not discriminate responsiveness to intubation. Br. J. Anaesth. 96, 323-329 (2006).
    • (2006) Br. J. Anaesth , vol.96 , pp. 323-329
    • Luginbühl, M.1    Rüfenacht, M.2    Korhonen, I.3    Gils, M.4    Jakob, S.5    Petersen-Felix, S.6
  • 12
    • 15944389902 scopus 로고    scopus 로고
    • EEG spectral entropy, heart rate, photoplethysmography and motor responses to skin incision during sevoflurane anaesthesia
    • Seitsonen, E.R. et al. EEG spectral entropy, heart rate, photoplethysmography and motor responses to skin incision during sevoflurane anaesthesia. Acta Anaesthesiol. Scand. 49, 284-292 (2005).
    • (2005) Acta Anaesthesiol. Scand , vol.49 , pp. 284-292
    • Seitsonen, E.R.1
  • 13
    • 33244484123 scopus 로고    scopus 로고
    • Novel multiparameter approach for measurement of nociception at skin incision during general anaesthesia
    • Rantanen, M. et al. Novel multiparameter approach for measurement of nociception at skin incision during general anaesthesia. Br. J. Anaesth. 96, 367-376 (2006).
    • (2006) Br. J. Anaesth , vol.96 , pp. 367-376
    • Rantanen, M.1
  • 14
    • 34248194833 scopus 로고    scopus 로고
    • Assessment of surgical stress during general anaesthesia
    • Huiku, M. et al. Assessment of surgical stress during general anaesthesia. Br. J. Anaesth. 98, 447-455 (2007).
    • (2007) Br. J. Anaesth , vol.98 , pp. 447-455
    • Huiku, M.1
  • 15
    • 0036206213 scopus 로고    scopus 로고
    • Performance of the ARX-derived auditory evoked potential index as an indicator of anesthetic depth: A comparison with bispectral index and hemodynamic measures during propofol administration
    • Struys, M.M. et al. Performance of the ARX-derived auditory evoked potential index as an indicator of anesthetic depth: a comparison with bispectral index and hemodynamic measures during propofol administration. Anesthesiology 96, 803-816 (2002).
    • (2002) Anesthesiology , vol.96 , pp. 803-816
    • Struys, M.M.1
  • 16
    • 0032756376 scopus 로고    scopus 로고
    • Isoflurane blunts electroencephalographic and thalamic-reticular formation responses to noxious stimulation in goats
    • Antognini, J.F. & Carstens, E. Isoflurane blunts electroencephalographic and thalamic-reticular formation responses to noxious stimulation in goats. Anesthesiology 91, 1770-1779 (1999).
    • (1999) Anesthesiology , vol.91 , pp. 1770-1779
    • Antognini, J.F.1    Carstens, E.2
  • 17
    • 0027136076 scopus 로고
    • Exaggerated anesthetic requirements in the preferentially anesthetized brain
    • Antognini, J.F. & Schwartz, K. Exaggerated anesthetic requirements in the preferentially anesthetized brain. Anesthesiology 79, 1244-1249 (1993).
    • (1993) Anesthesiology , vol.79 , pp. 1244-1249
    • Antognini, J.F.1    Schwartz, K.2
  • 18
    • 0027467413 scopus 로고
    • Anesthetic potency (MAC) is independent of forebrain structures in the rat
    • Rampil, I.J., Mason, P. & Singh, H. Anesthetic potency (MAC) is independent of forebrain structures in the rat. Anesthesiology 78, 707-712 (1993).
    • (1993) Anesthesiology , vol.78 , pp. 707-712
    • Rampil, I.J.1    Mason, P.2    Singh, H.3
  • 19
    • 0036164333 scopus 로고    scopus 로고
    • Efficient trial design for eliciting a pharmacokinetic-pharmacodynamic model-based response surface describing the interaction between two intravenous anesthetic drugs
    • Short, T.G., Ho, T.Y., Minto, C.F., Schnider, T.W. & Shafer, S.L. Efficient trial design for eliciting a pharmacokinetic-pharmacodynamic model-based response surface describing the interaction between two intravenous anesthetic drugs. Anesthesiology 96, 400-408 (2002).
    • (2002) Anesthesiology , vol.96 , pp. 400-408
    • Short, T.G.1    Ho, T.Y.2    Minto, C.F.3    Schnider, T.W.4    Shafer, S.L.5
  • 20
    • 0030873246 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic interactions between opioids and propofol
    • Vuyk, J. Pharmacokinetic and pharmacodynamic interactions between opioids and propofol. J. Clin. Anesth. 9, 23S-26S (1997).
    • (1997) J. Clin. Anesth , vol.9
    • Vuyk, J.1
  • 21
    • 2542471369 scopus 로고    scopus 로고
    • Pharmacodynamic interaction between propofol and remifentanil regarding hypnosis, tolerance of laryngoscopy, bispectral index, and electroencephalographic approximate entropy
    • Bouillon, T.W. et al. Pharmacodynamic interaction between propofol and remifentanil regarding hypnosis, tolerance of laryngoscopy, bispectral index, and electroencephalographic approximate entropy. Anesthesiology 100, 1353-1372 (2004).
    • (2004) Anesthesiology , vol.100 , pp. 1353-1372
    • Bouillon, T.W.1
  • 22
    • 1642458343 scopus 로고    scopus 로고
    • Mixed-effects modeling of the intrinsic ventilatory depressant potency of propofol in the non-steady state
    • Bouillon, T., Bruhn, J., Radu-Radulescu, L., Andresen, C., Cohane, C. & Shafer, S.L. Mixed-effects modeling of the intrinsic ventilatory depressant potency of propofol in the non-steady state. Anesthesiology 100, 240-250 (2004).
    • (2004) Anesthesiology , vol.100 , pp. 240-250
    • Bouillon, T.1    Bruhn, J.2    Radu-Radulescu, L.3    Andresen, C.4    Cohane, C.5    Shafer, S.L.6
  • 24
    • 33746633896 scopus 로고    scopus 로고
    • Opioid-volatile anesthetic synergy: A response surface model with remifentanil and sevoflurane as prototypes
    • Manyam, S.C. et al. Opioid-volatile anesthetic synergy: a response surface model with remifentanil and sevoflurane as prototypes. Anesthesiology 105, 267-278 (2006).
    • (2006) Anesthesiology , vol.105 , pp. 267-278
    • Manyam, S.C.1
  • 25
    • 33744949310 scopus 로고    scopus 로고
    • Interaction of propofol and sevoflurane on loss of consciousness and movement to skin incision during general anesthesia
    • Harris, R.S., Lazar, O., Johansen, J.W. & Sebel, P.S. Interaction of propofol and sevoflurane on loss of consciousness and movement to skin incision during general anesthesia. Anesthesiology 104, 1170-1175 (2006).
    • (2006) Anesthesiology , vol.104 , pp. 1170-1175
    • Harris, R.S.1    Lazar, O.2    Johansen, J.W.3    Sebel, P.S.4
  • 26
    • 0033835606 scopus 로고    scopus 로고
    • Patient safety and simulation-based medical education
    • Ziv, A., Small, S.D. & Wolpe, P.R. Patient safety and simulation-based medical education. Med. Teach. 22, 489-495 (2000).
    • (2000) Med. Teach , vol.22 , pp. 489-495
    • Ziv, A.1    Small, S.D.2    Wolpe, P.R.3
  • 27
    • 0031442021 scopus 로고    scopus 로고
    • Propofol anesthesia and rational opioid selection: Determination of optimal EC50-EC95 propofol-opioid concentrations that assure adequate anesthesia and a rapid return of consciousness
    • Vuyk, J., Mertens, M.J., Olofsen, E., Burm, A.G. & Bovill, J.G. Propofol anesthesia and rational opioid selection: determination of optimal EC50-EC95 propofol-opioid concentrations that assure adequate anesthesia and a rapid return of consciousness. Anesthesiology 87, 1549-1562 (1997).
    • (1997) Anesthesiology , vol.87 , pp. 1549-1562
    • Vuyk, J.1    Mertens, M.J.2    Olofsen, E.3    Burm, A.G.4    Bovill, J.G.5
  • 28
    • 0019351829 scopus 로고
    • Interactions among ventilation, the circulation, and the uptake and distribution of halothane - use of a hybrid computer multiple model: I. The basic model
    • Fukui, Y. & Smith, N.T. Interactions among ventilation, the circulation, and the uptake and distribution of halothane - use of a hybrid computer multiple model: I. The basic model. Anesthesiology 54, 107-118 (1981).
    • (1981) Anesthesiology , vol.54 , pp. 107-118
    • Fukui, Y.1    Smith, N.T.2
  • 29
    • 33746589655 scopus 로고    scopus 로고
    • Anesthesia Advisory Display (AAD): Real time guidance through the pharmacokinetic and interaction pharmacodynamic relationship during simultaneous administration of multiple drugs
    • Schumacher, P.M., Bouillon, T.W., Leibundgut, D., Sartori, V. & Zbinden, A.M. Anesthesia Advisory Display (AAD): real time guidance through the pharmacokinetic and interaction pharmacodynamic relationship during simultaneous administration of multiple drugs. Anesthesiology 101, A504 (2004).
    • (2004) Anesthesiology , vol.101
    • Schumacher, P.M.1    Bouillon, T.W.2    Leibundgut, D.3    Sartori, V.4    Zbinden, A.M.5
  • 31
    • 33646368371 scopus 로고    scopus 로고
    • Drug delivery as control task: Improving performance in a common anesthetic task
    • Drews, F.A., Syroid, N., Agutter, J., Strayer, D.L. & Westenskow, D.R. Drug delivery as control task: improving performance in a common anesthetic task. Hum. Factors 48, 85-94 (2006).
    • (2006) Hum. Factors , vol.48 , pp. 85-94
    • Drews, F.A.1    Syroid, N.2    Agutter, J.3    Strayer, D.L.4    Westenskow, D.R.5
  • 32
    • 18244368961 scopus 로고    scopus 로고
    • Development and evaluation of a graphical anesthesia drug display
    • Syroid, N.D. et al. Development and evaluation of a graphical anesthesia drug display. Anesthesiology 96, 565-575 (2002).
    • (2002) Anesthesiology , vol.96 , pp. 565-575
    • Syroid, N.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.