BRCA2 gene mutations in Slovenian male breast cancer patients

Genetic Testing

Volumn 12, Issue 2, 2008, Pages 203-209

  Besic, Nikola ^a   Cernivc, Barabara ^a   De Grève, Jacques ^b   Lokar, Katarina ^a   Krajc, Mateja ^a   Novakovic, Srdan ^a   Zgajnar, Janez ^a   Teugels, Erik ^c  

^a INSTITUTE OF ONCOLOGY   (Slovenia)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRCA2 GENE; BREAST CANCER; CANCER PATIENT; CLINICAL ARTICLE; FAMILY HISTORY; GENE FREQUENCY; GENE IDENTIFICATION; GENE MUTATION; GENETIC COUNSELING; GENETIC SCREENING; GERM LINE; HUMAN; HUMAN GENOME; MALE; MALE BREAST; MUTATION RATE; ONCOGENE; OVARY CANCER; RELATIVE; SLOVENIA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS, MALE; DNA MUTATIONAL ANALYSIS; FOUNDER EFFECT; GENES, BRCA2; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GERM-LINE MUTATION; HUMANS; MALE; MIDDLE AGED; SLOVENIA;

EID: 45549086553     PISSN: 10906576     EISSN: None     Source Type: Journal    
DOI: 10.1089/gte.2007.0071     Document Type: Article

References (34)

1. Breast Cancer Information Core Internet Website (2005). (http://www.nhgri.nih.gov/Intramural_research/Lab_transfer/Bic/)
2. Antoniou A, Pharoah PD, Narod S, Risch HA, Eyfjord JE, Hopper JL, Loman N, Olsson H, Johannsson O, Borg A, Pasini B, Radice P, Manoukian S, Eccles DM, Tang N, Olah E, Anton-Culver H, Warner E, Lubinski J, Gronwald J, Gorski B, Tulinius H, Thorlacius S, Eerola H, Nevanlinna H, Syrjäkoski K, Kallioniemi OP, Thompson D, Evans C, Peto J, Lalloo F, Evans DG, Easton DF (2003) Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet 72:1117-1130.
3. Basham VM, Lipscombe JM, Ward JM, Gayther SA, Ponder BA, Easton DF, Pharoah PD (2002) BRCA1 and BRCA2 mutations in a population-based study of male breast cancer. Breast Cancer Res 4:R2.
4. Couch FJ, Farid LM, DeShano ML, Tavtigian SV, Calzone K, Campeau L, Peng Y, Bogden B, Chen Q, Neuhausen S, Shattuck-Eidens D, Godwin AK, Daly M, Radford DM, Sedlacek S, Rommens J, Simard J, Garber J, Merajver S, Weber BL (1996) BRCA2 germline mutations in male breast cancer cases and breast cancer families. Nat Genet 13:123-125.
5. Csokay B, Udvarhelyi N, Sulyok Z, Besznyak I, Ramus S, Ponder B, Olah E (1999) High frequency of germ-line BRCA2 mutations among Hungarian male breast cancer patients without family history. Cancer Res 59:995-998.
6. Diez O, Cortes J, Domenech M, Pericay C, Brunet J, Alonso C, Baiget M (2000) BRCA2 germ-line mutations in Spanish male breast cancer patients. Ann Oncol 11:81-84.
7. Donegan WL, Redlich PN (1996) Breast cancer in men. Surg Clin North Am 76:343-363.
8. Euhus DM, Smith KC, Robinson L, Stucky A, Olopade OI, Cummings S, Garber JE, Chittenden A, Mills GB, Rieger P, Esserman L, Crawford B, Hughes KS, Roche CA, Ganz PA, Seldon J, Fabian CJ, Klemp J, Tomlinson G (2002) Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO. J Natl Cancer Inst 94:844-851.
9. Evans DG, Bulman M, Young K, Gokhale D, Lalloo F (2001) High detection rate for BRCA2 mutations in male breast cancer families from North West England. Fam Cancer 1:131-133.
10. Friedman LS, Gayther SA, Kurosaki T, Gordon D, Noble B, Casey G, Ponder BA, Anton-Culver H (1997) Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population. Am J Hum Genet 60:313-319.
11. Haraldsson K, Loman N, Zhang QX, Johannsson O, Olsson H, Borg A (1998) BRCA2 germ-line mutations are frequent in male breast cancer patients without a family history of the disease. Cancer Res 58:1367-1371.
12. Hecht JR, Winchester DJ (1994) Male breast cancer. Am J Clin Pathol 102:S25-S30.
13. Hogervorst FB, Cornelis RS, Bout M, van Vliet M, Oosterwijk JC, Olmer R, Bakker B, Klijn JG, Vasen HF, Meijers-Heijboer H, Menko FH, Cornelisse CJ, den Dunnen JT, Devilee P, van Ommen G-J (1995) Rapid detection of BRCA1 mutations by the protein truncation test. Nat Genet 10:208-212.
14. Krajc M, de Greve J, Goelen G, Teugels E (2002) BRCA2 founder mutation in Slovenian breast cancer families. Eur J Hum Genet 10:879-882.
15. Krajc M, Teugels E, Zgajnar J, Goelen G, Besic N, Hocevar M, Novakovic S, de Greve J (2007) BRCA1/2 mutation screening in the first 200 tested Slovenian breast/ovarian cancer families. (In press).
16. Kwiatkowska E, Teresiak M, Filas V, Karczewska A, Breborowicz D, Mackiewicz A (2003) BRCA2 mutations and androgen receptor expression as independent predictors of outcome of male breast cancer patients. Clin Cancer Res 9:4452-4459.
17. Mavraki E, Gray IC, Bishop DT, Spurr NK (1997) Germline BRCA2 mutations in men with breast cancer. Br J Cancer 76:1428-1431.
18. Ottini L, Masala G, D'Amico C, Mancini B, Saieva C, Aceto G, Gestri D, Vezzosi V, Falchetti M, de Marco M, Paglierani M, Cama A, Bianchi S, Mariani-Costantini R, Palli D (2003) BRCA1 and BRCA2 mutation status and tumor characteristics in male breast cancer: a population-based study in Italy. Cancer Res 63:342-347.
19. Pages S, Caux V, Stoppa-Lyonnet D, Tosi M (2001) Screening of male breast cancer and of breast-ovarian cancer families for BRCA2 mutations using large bifluorescent amplicons. Br J Cancer 84:482-488.
20. Palli D, Masala G, Mariani-Costantini R, Zanna I, Saieva C, Sera F, Decarli A, Ottini L (2004) A gene-environment interaction between occupation and BRCA1/BRCA2 mutations in male breast cancer? Eur J Cancer 40:2474-2479.
21. Petrij-Bosch A, Peelen T, van Vliet M, van Eijk R, Olmer R, Drusedau M, Hogervorst FB, Hageman S, Arts PJ, Ligtenberg MJ, Meijers-Heijboer H, Klijn JG, Vasen HF, Cornelisse CJ, van't Veer LJ, Bakker E, van Ommen GJ, Devilee P (1997) BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients. Nat Genet 17:341-345.
22. Primic-Zakelj M (2004) Cancer incidence in Slovenia 2001. Report No 43. Epidemiology and cancer registry, Institute of Oncology Ljubljana, Ljubljana.
23. Roa BB, Boyd AA, Volcik K, Richards CS (1996) Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nat Genet 14:185-187.
24. Santarosa M, Dolcetti R, Magri MD, Crivellari D, Tibiletti MG, Gallo A, Tumolo S, Della Puppa L, Furlan D, Boiocchi M, Viel A (1999) BRCA1 and BRCA2 genes: role in hereditary breast and ovarian cancer in Italy. Int J Cancer 83:5-9.
25. Sasco AJ, Lowenfels AB, Pasker-de Jong P (1993) Review article: epidemiology of male breast cancer. A meta-analysis of published case-control studies and discussion of selected aetiological factors. Int J Cancer 53:538-549.
26. Shih HA, Nathanson KL, Seal S, Collins N, Stratton MR, Rebbeck TR, Weber BL (2000) BRCA1 and BRCA2 mutations in breast cancer families with multiple primary cancers. Clin Cancer Res 6:4259-4264.
27. Struewing JP, Coriaty ZM, Ron E, Livoff A, Konichezky M, Cohen P, Resnick MB, Lifzchiz-Mercerl B, Lew S, Iscovich J (1999) Founder BRCA1/2 mutations among male patients with breast cancer in Israel. Am J Hum Genet 65:1800-1802.
28. Sverdlov RS, Barshack I, Bar Sade RB, Baruch RG, Hirsh-Yehezkel G, Dagan E, Feinmesser M, Figer A, Friedman E (2000) Genetic analyses of male breast cancer in Israel. Genet Test 4:313-317.
29. Syrjakoski K, Kuukasjarvi T, Waltering K, Haraldsson K, Auvinen A, Borg A, Kainu T, Kallioniemi OP, Koivisto PA (2004) BRCA2 mutations in 154 Finnish male breast cancer patients. Neoplasia 6:541-545.
30. Thomas DB, Jimenez LM, McTiernan A, Rosenblatt K, Stalsberg H, Stemhagen A, Thompson WD, Curnen MG, Satariano W, Austin DF, Greenberg RS, Key C, Kolonel LN, West DW (1992) Breast cancer in men: risk factors with hormonal implications. Am J Epidemiol 135:734-748.
31. Thorlacius S, Olafsdottir G, Tryggvadottir L, Neuhausen S, Jonasson JG, Tavtigian SV, Tulinius H, Ogmundsdottir HM, Eyfjord JE (1996) A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes. Nat Genet 13:117-119.
32. van der Hout AH, van den Ouweland AM, van der Luijt RB, Gille HJ, Bodmer D, Brüggenwirth H, Mulder IM, van der Vlies P, Elfferich P, Huisman MT, ten Berge AM, Kromosoeto J, Jansen RP, van Zon PH, Vriesman T, Arts N, Lange MB, Oosterwijk JC, Meijers-Heijboer H, Ausems MG, Hoogerbrugge N, Verhoef S, Halley DJ, Vos YJ, Hogervorst F, Ligtenberg M, Hofstra RM (2006) A DGGE system for comprehensive mutation screening of BRCA1 and BRCA2: application in a Dutch cancer clinic setting. Hum Mutat 27:654-666.
33. Warner E, Foulkes W, Goodwin P, Meschino W, Blondal J, Paterson C, Ozcelik H, Goss P, Allingham-Hawkins D, Hamel N, Di Prospero L, Contiga V, Serruya C, Klein M, Moslehi R, Honeyford J, Liede A, Glendon G, Brunet JS, Narod S (1999) Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer. J Natl Cancer Inst 91:1241-1247.
34. Wolpert N, Warner E, Seminsky MF, Futreal A, Narod SA (2000) Prevalence of BRCA1 and BRCA2 mutations in male breast cancer patients in Canada. Clin Breast Cancer 1:57-63; discussion 64-65.