A possible mechanism for controlling processive transport by microtubule-associated proteins

Neuroscience Research

Volumn 61, Issue 4, 2008, Pages 347-350

  Shahpasand, Kourosh ^a   Ahmadian, Shahin ^a   Riazi, Gholam H ^a  

^a UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Inter microtubular spaces; MAPs; Processive transport; Steric constraints

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 2; POLYMER; TAU PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BRUSH BORDER; CYTOSKELETON; DENDRITE; INTERCELLULAR SPACE; INTRACELLULAR TRANSPORT; MEMBRANE VESICLE; MICROTUBULE; MICROTUBULE ASSEMBLY; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER; NERVE FIBER TRANSPORT; NEUROFILAMENT; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROCESS MODEL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RADIAL BASED FUNCTION; STEREOSPECIFICITY; TRANSPORT KINETICS; TRANSPORT VESICLE;

ANIMALS; AXONAL TRANSPORT; MICROTUBULE-ASSOCIATED PROTEINS;

EID: 45449114179     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2008.04.010     Document Type: Article

References (41)

1. Avila J., Santa M., Perez M., Hernandez F., and Moreno F. Tau phosphorylation, aggregation and cell toxicity. J. Biomed. Biotechnol. (2006) 1-5
2. Belanger D., Farah C., Nguyen M., Lauzon M., Cornibert S., and Leclerc N. The projection domain of MAP2b regulates microtubule protrusion and process formation in Sf9 cells. J. Cell Sci. 115 (2002) 1523-1539
3. Billingsley M.L., and Kincaid R.L. Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubules interaction, intracellular trafficking and neurodegeneration. Biochem. J. 323 (1997) 577-591
4. Bright J.N., Woolf T.B., and Hoh J.H. Predicting properties of intrinsically unstructured proteins. Prog. Biophys. Mol. Biol. 76 (2001) 131-173
5. Brown H.G., and Hoh J.H. Entropic exclusion by neurofilament side arms: a mechanism for maintaining inter filament spacing. Biochemistry 36 (1997) 15035-15040
6. Chen J., Kanai Y., Cowan N.J., and Hirokawa N. Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature 360 (1992) 674-677
7. Cruz A., Schwarzel M., Schulze S., Niyyati M., Heisenburg M., and Kratzschamer D. Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila. Mol. Biol. Cell. 16 (2005) 2433-2442
8. Dixit R., Ross J.L., Goldman Y.E., and Holzbaur E.L. Differential regulation of dynein and kinesin motor proteins by tau. Science 319 (2008) 1086-1089
9. Ebneth A., Godemann R., Stamer K., Illenberger S., Triczek B., and Mandelkow E. Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria and endoplasmic reticulum: implications for Alzheimer's disease. J. Cell Biol. 143 (1998) 777-794
10. Frappier T.F., Georgieff I.S., Brown K., and Shelanski M.L. Tau regulation of microtubule-microtubule spacing and bundling. J. Neurochem. 63 (1994) 2288-2294
11. Frappier T., Liang N.S., Brown K., Leung C.L., Lynch T., Liem K.H., and Shelanski M.L. Abnormal microtubule packing in processes of SF9 cells expressing the FTDP-17 V337M tau mutation. FEBS Lett. 455 (1999) 262-266
12. Friedrich P., and Aszodi A. MAP2-a sensitive cross-linker and adjustable spacer in dendritic architecture. FEBS Lett. 295 (1991) 5-9
13. Fuchs E., and Clevland D.W. A structural scaffolding of intermediate filaments in health and disease. Science 279 (1998) 514-519
14. Grant P., and Pant H.C. Neurofilament protein synthesis and phosphorylation. J. Neurocytol. 29 (2000) 843-872
15. Gustke N., Trinczek B., Biernat J., Mandelkow E.M., and Mandelkow E. Domains of tau protein and interaction with microtubules. Biochemistry 33 (1994) 9511-9522
16. Hagestedt T., Lichtenberg B., Wille H., Mandelkow E.M., and Mandelkow E. Tau-protein becomes long and more stiff upon phosphorylation; correlation between paracrystalline structure and degree of phosphorylation. J. Cell Biol. 109 (1989) 1643-1651
17. Heidemann S.R. Cytoplasmic mechanisms of axonal and dendritic growth in neurons. Int. Rev. Cytol. 165 (1996) 235-296
18. Hernandez F., and Avila J. Tauopathies. Cell. Mol. Life Sci. 64 (2007) 2219-2233
19. Holzwarth G., Bonin K., and Hill B.D. Force required of kinesin during processive transport through cytoplasm. Biophys. J. 82 (2002) 1784-1790
20. Jimenez E.M., Gonzalez C., Dawson H.M., Vitec M.P., and Avila J. Role of MAP1B in axonal retrograde transport of mitochondria. Biochem. J. 397 (2006) 53-59
21. Kumar S., Yin X., Trapp B.D., Hoh J.H., and Paulaitis M.E. Role of long range repulsive forces in organizing axonal neurofilament distributions: evidence from mice deficient in myelin associated glycoprotein. J. Neurosci. Res. 68 (2002) 681-690
22. Kurz J., Robley C., and Williams J.R. Microtubule-associated proteins and the flexibility of microtubules. Biochemistry 34 (1995) 13374-13380
23. Lee M.K., and Cleveland D.W. Neuronal intermediate filaments. Ann. Rev. Neurosci. 19 (1996) 187-217
24. Lewis S.A., Wang D., and Cowan N.J. MAP2 shares a microtubule binding motif with tau protein. Science 242 (1988) 936-939
25. Mandelkow E.M., Thies E., Trinkzeck B., Biernat J., and Mandelkow E. MARK/PAR1 kinase is a regulator of microtubule dependent transport in axons. J. Cell Sci. 167 (2004) 99-110
26. Marx A., Muller J., Mandelkow E.M., Hoenger A., and Mandelkow E. Interaction of kinesin motors, microtubules, and MAPs. J. Mus. Res. Cell Motil. 27 (2006) 125-137
27. Marx A., Pless J., Mandelkow E.M., and Mandelkow E. On the rigidity of the cytoskeleton: are MAPs cross-linkers or spacers of microtubules?. Cell Mol. Biol. 46 (2000) 949-965
28. Mata M., Kupina N., and Fink D.J. Phosphorylation-dependent neurofilament epitopes are reduced at the Node of Ranvier. J. Neurocytol. 21 (1992) 199-210
29. Mc Intosh J.R. Bridges between microtubules. J. Cell Biol. 61 (1974) 166-187
30. Meyhoefer E., and Howard J. The force generated by a single kinesin molecule against an elastic load. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 574-578
31. Mukhopadhyay R., Kumar S., and Hoh H.J. Molecular mechanisms for organizing the neuronal cytoskeleton. BioEssays 26 (2004) 1017-1025
32. Pevalova M., Filipcik P., Novak M., Avila J., and Iqbal K. Post-translational modifications of tau protein. Bratisl. Lek. Listy. 107 (2006) 346-353
33. Sanchez C., Diaz-Nido J., and Avila J. Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function. Prog. Neurobiol. 61 (2000) 133-168
34. Santarella R., Skiniotis G., Goldie K., Tittman P., Gross H., Mandelkow E.M., Mandelkow E., and Hoenger A. Surface-decoration of microtubules by human tau. J. Mol. Biol. 339 (2004) 539-553
35. Shahani N., and Brandt R. Functions and malfunctions of the tau proteins. Cell Mol. Life Sci. 59 (2002) 1668-1680
36. Sihag R., Inagaki M., Yamaguchi M., Shea T., and Pant H. Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments. Exp. Cell Res. 313 (2007) 2098-2109
37. Stamer K., Vogel R., Thies E., Mandelkow E.M., and Mandelkow E. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J. Cell Biol. 156 (2002) 1051-1063
38. Tatebayashi Y., Haque N., Tung Y., Iqbal K., and Grundke-Iqbal I. Role of tau phosphorylation by glycogen synthase kinase-3W in the regulation of organelle transport. J. Cell Sci. 117 (2004) 1653-1663
39. Teng J., Takei Y., Harada A., Nakata T., Chen J., and Hirokawa A. Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth and microtubule organization. J. Cell Biol. 155 (2001) 65-76
40. Tokuda M., and Hatase O. Regulation of neuronal plasticity in the central nervous system by phosphorylation and dephosphorylation. Mol. Neurobiol. 17 (1998) 137-156
41. Zhulina E.B., and Leermakers F. A self-consistent field analysis of the neurofilament brush with amino-acid resolution. Biophys. J. 93 (2007) 1421-1430