[18F]FBAU 3′,5′-dibenzoate, a lipophilic prodrug, enhances brain uptake of the cell proliferation tracer [18F]FBAU

Nuclear Medicine and Biology

Volumn 35, Issue 5, 2008, Pages 635-643

  Kao, Chih Hao K ^a,b   Xie, Heng Li ^a   Liao, Chia Hsin ^a,c   Chen, Wen Min ^a   Kao, Pan Fu ^a,b  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b TZU CHI COLLEGE OF TECHNOLOGY   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Brain uptake; FBAU; PET; Prodrug; Proliferation marker; Thymidine analogs

Indexed keywords

1 (2 DEOXY 2 FLUORO BETA DEXTRO ARABINOFURANOSYL) 5 BROMOURACIL F 18; 1 (2 DEOXY 3,5 O DIBENZOYL 2 FLUORO BETA DEXTRO ARABINOFURANOSYL) 5 BROMOURACIL F 18; DNA; FLUORINE 18; PRODRUG; TRACER; 1 (2 FLUORO 2 DEOXY 3,5 O DIBENZOYLARABINOFURANOSYL) 5 BROMOURACIL; 1 (2 FLUORO 2 DEOXYARABINOFURANOSYL) 5 BROMOURACIL; 1-(2-FLUORO-2-DEOXY-3,5-O-DIBENZOYLARABINOFURANOSYL)-5-BROMOURACIL; 1-(2-FLUORO-2-DEOXYARABINOFURANOSYL)-5-BROMOURACIL; 5 BROMOURACIL; DRUG DERIVATIVE; LIPID; RADIOPHARMACEUTICAL AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; BLOOD BRAIN BARRIER; BRAIN; BRAIN CELL; CELL PROLIFERATION; DNA SYNTHESIS; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG UPTAKE; INTESTINE; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; PARTITION COEFFICIENT; RADIOACTIVITY; RAT; SPLEEN; SYNTHESIS; THIN LAYER CHROMATOGRAPHY; ANIMAL; BIOSYNTHESIS; BIOTRANSFORMATION; CENTRIFUGATION; CHEMISTRY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOTOPE LABELING; METABOLISM; PHYSICAL CHEMISTRY; SCINTISCANNING; SOLUBILITY; SPRAGUE DAWLEY RAT;

ANIMALS; BIOTRANSFORMATION; BRAIN; BROMOURACIL; CELL PROLIFERATION; CENTRIFUGATION; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DNA; INTESTINES; ISOTOPE LABELING; LIPIDS; MALE; MICE; MICE, INBRED ICR; PRODRUGS; RADIOACTIVE TRACERS; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SPLEEN;

EID: 45449105181     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2008.04.004     Document Type: Article

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