Ethanol inhibits gap-junctional coupling between P19 cells

Alcoholism: Clinical and Experimental Research

Volumn 28, Issue 9, 2004, Pages 1284-1290

  Wentlandt, Kirsten ^a   Kushnir, Moshe ^b   Naus, Christian C G ^c   Carlen, Peter L ^a,d  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

^d TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Connexins; Dye Coupling; Ethanol; Gap Junctions; P19 Cell Line

Indexed keywords

ALCOHOL; CALCEIN; CONNEXIN 26; CONNEXIN 43; GAP JUNCTION PROTEIN; IODINE DERIVATIVE;

ALCOHOL WITHDRAWAL; ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL CULTURE; CELL FUNCTION; CELL JUNCTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; FLOW CYTOMETRY; GEL ELECTROPHORESIS; IMMUNOBLOTTING; INCUBATION TIME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; CELL COMMUNICATION; CELL LINE, TUMOR; ETHANOL; GAP JUNCTIONS; MICE;

ANIMALIA;

EID: 4544355909     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000139705.17646.BA     Document Type: Article

References (41)

1. Abou Hashieh I, Mathieu S, Besson F, Gerolami A (1996) Inhibition of gap junction intercellular communications of cultured rat hepatocytes by ethanol: role of ethanol metabolism. J Hepatol 24:360-367.
2. Aizawa T, Haga S, Yoshikawa K (1991) Neural differentiation-associated generation of microglia-like phagocytes in murine embryonal carcinoma cell line. Brain Res Dev Brain Res 59:89-97.
3. Bain G, Ray WJ, Yao M, Gottlieb DI (1994) From embryonal carcinoma cells to neurons: the P19 pathway. Bioessays 16:343-348.
4. Belliveau DJ, Bechberger JF, Rogers KA, Naus CC (1997) Differential expression of gap junctions in neurons and astrocytes derived from P19 embryonal carcinoma cells. Dev Genet 21:187-200.
5. Belliveau DJ, Naus CC (1995) Cellular localization of gap junction mRNAs in developing rat brain. Dev Neurosci 17:81-96.
6. Bevans CG, Kordel M, Rhee SK, Harris AL (1998) Isoform composition of connexin channels determines selectivity among second messengers and uncharged molecules. J Biol Chem 273:2808-2816.
7. Bokkala S, Reis HM, Rubin E, Joseph SK (2001) Effect of angiotensin II and ethanol on the expression of connexin 43 in WB rat liver epithelial cells. Biochem J 357:769-777.
8. Bruzzone R, White TW, Goodenough DA (1996a) The cellular Internet: on-line with connexins. Bioessays 18:709-718.
9. Bruzzone R, White TW, Paul DL (1996b) Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem 238:1-27.
10. Davidson JS, Baumgarten IM (1988) Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. J Pharmacol Exp Ther 246:1104-1107.
11. Dermietzel R (1998) Gap junction wiring: a 'new' principle in cell-to-cell communication in the nervous system? Brain Res Brain Res Rev 26:176-183.
12. Essodaigui M, Broxterman HJ, Garnier-Suillerot A (1998) Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein. Biochemistry 37:2243-2250.
13. Goldberg GS, Lampe PD, Nicholson BJ (1999) Selective transfer of endogenous metabolites through gap junctions composed of different connexins. Nat Cell Biol 1:457-459.
14. Hashieh IA, Mathieu S, Gerolami A (1992) Effects of ethanol on intercellular communications and polarization of hepatocytes in short-term culture. Hepatology 15:751-756.
15. Hashieh IA, Remy L, Mathieu S, Gerolami A (1989) The effects of monensin on the transport of horseradish peroxidase into intracellular lumina in cultured rat hepatocytes. Hepatology 10:61-65.
16. Johnston MF, Simon SA, Ramon F (1980) Interaction of anaesthetics with electrical synapses. Nature 286:498-500.
17. Jones-Villeneuve EM, McBurney MW, Rogers KA, Kalnins VI (1982) Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J Cell Biol 94:253-262.
18. Jones-Villeneuve EM, Rudnicki MA, Harris JF, McBurney MW (1983) Retinoic acid-induced neural differentiation of embryonal carcinoma cells. Mol Cell Biol 3:2271-2279.
19. Klausner RD, Wolf DE (1980) Selectivity of fluorescent lipid analogues for lipid domains. Biochemistry 19:6199-6203.
20. Kumar R, Wilders R, Joyner RW, Jongsma HJ, Verheijck EE, Golod DA, van Ginneken AC, Goolsby WN (1996) Experimental model for an ectopic focus coupled to ventricular cells. Circulation 94:833-841.
21. Kwak BR, Hermans MM, De Jonge HR, Lohmann SM, Jongsma HJ, Chanson M (1995) Differential regulation of distinct types of gap junction channels by similar phosphorylating conditions. Mol Biol Cell 6:1707-1719.
22. Martinez SE, Vaglenova J, Sabriai J, Martinez MC, Farres J, Pares X (2001) Distribution of alcohol dehydrogenase mRNA in the rat central nervous system. Eur J Biochem 268:5045-5056.
23. McBurney MW (1993) P19 embryonal carcinoma cells. Int J Dev Biol 37:135-140.
24. Moreno AP, Rook MB, Fishman GI, Spray DC (1994) Gap junction channels: distinct voltage-sensitive and -insensitive conductance states. Biophys J 67:113-119.
25. Mummery CL, Feijen A, Moolenaar WH, van den Brink CE, de Laat SW (1986) Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors. Exp Cell Res 165:229-242.
26. Mummery CL, van den Brink CE, de Laat SW (1987) Commitment to differentiation induced by retinoic acid in P19 embryonal carcinoma cells is cell cycle dependent. Dev Biol 121:10-19.
27. Nadarajah B, Jones AM, Evans WH, Parnavelas JG (1997) Differential expression of connexins during neocortical development and neuronal circuit formation. J Neurosci 17:3096-3111.
28. Naus CC, Bani Y (1998) Gap junctional communication in the developing central nervous system. Cell Biol Int 22:751-763.
29. +] in rat astrocytes. Glia 16:7-15.
30. Paul DL (1986) Molecular cloning of cDNA for rat liver gap junction protein. J Cell Biol 103:123-134.
31. Perez-Velazquez JL, Valiante TA, Carlen PL (1994) Modulation of gap junctional mechanisms during calcium-free induced field burst activity: a possible role for electrotonic coupling in epileptogenesis. J Neurosci 14:4308-4317.
32. Renau-Piqueras J, Miragall F, Guerri C, Sancho-Tello M, Baguena-Cervellera R (1987) Prenatal exposure to ethanol alters lateral plasma membranes and gap junctions of newborn rat hepatocytes as revealed by freeze-fracture. J Submicrosc Cytol 19:397-404.
33. + concentration in astrocytes. Glia 20:299-307.
34. Sato T (1994) Changes in the gap junction of rat exocrine pancreatic cells induced by long-term ethanol ingestion. Tohoku J Exp Med 172:39-49.
35. Simburger E, Stang A, Kremer M, Dermietzel R (1997) Expression of connexin43 mRNA in adult rodent brain. Histochem Cell Biol 107:127-137.
36. Simpson I, Rose B, Loewenstein WR (1977) Size limit of molecules permeating the junctional membrane channels. Science 195:294-296.
37. Spray DC, Harris AL, Bennett MV (1981a) Gap junctional conductance is a simple and sensitive function of intracellular pH. Science 211:712-715.
38. Spray DC, Harris AL, Bennett MV (1981b) Comparison of pH and calcium dependence of gap junctional conductance. Kroc Found Ser 15:445-461.
39. Staines WA, Craig J, Reuhl K, McBurney MW (1996) Retinoic acid treated Pl9 embryonal carcinoma cells differentiate into oligodendrocytes capable of myelination. Neuroscience 71:845-853.
40. Sutor B (2002) Gap junctions and their implications for neurogenesis and maturation of synaptic circuitry in the developing neocortex. Results Probl Cell Differ 39:53-73.
41. White TW, Paul DL (1999) Genetic diseases and gene knockouts reveal diverse connexin functions. Annu Rev Physiol 61:283-310.