Gap junctional communication in the developing central nervous system

Cell Biology International

Volumn 22, Issue 11-12, 1998, Pages 751-763

  Naus, Christian C G ^a   Bani Yaghoub, Mahmud ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Connexin; Development; Gap junctions; Intercellular communication

Indexed keywords

CONNEXIN 43; GAP JUNCTION PROTEIN;

ASTROCYTE; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL COMMUNICATION; CELL JUNCTION; CELL MIGRATION; GLIA CELL; NEOCORTEX; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; OLIGODENDROGLIA; REVIEW; ANIMAL; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; GENETICS; GLIA; HUMAN; METABOLISM; MUTATION; NERVE CELL; PHYSIOLOGY; PRENATAL DEVELOPMENT; ULTRASTRUCTURE;

ANIMALS; CELL COMMUNICATION; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; CONNEXINS; GAP JUNCTIONS; HUMANS; MUTATION; NEUROGLIA; NEURONS;

EID: 0032300072     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.1998.0391     Document Type: Article

References (136)

1. AICARDI J, 1994. The place of neuronal migration abnormalities in child neurology. Can J Neurol Sci 21: 185-193.
2. ANDERS JJ, 1988. Lactic acid inhibition of gap junctional intercellular communication in in vitro astrocytes as measured by fluorescence recovery after laser photobleaching. Glia 1: 371-379.
3. ANDO M, TATEMATSU T, KUNII S, NAGATA Y, 1994. The intercellular communication via nitric oxide and its regulation in coupling of cyclic GMP synthesis upon stimulation of muscarinic cholinergic receptors in rat superior cervical sympathetic ganglia. Brain Res 650: 283-288.
4. ANZINI P, NEUBERG DHH, SCHACHNER M, NELLES E, WILLECKE K, ZIELASEK J, TOYKA KV, SUTER U, MARTINI R, 1997. Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32. J Neurosci 17: 4545-4551.
5. BANI-YAGHOUB M, BECHBERGER JF, NAUS CCG, 1997. Reduction of connexin43 expression and dye-coupling during neuronal differentiation of human NTera2/Clone D1 cells. J Neurosci Res 49: 19-31.
6. BANI-YAGHOUB M, BECHBERGER JF, UNDERHILL TM, NAUS CCG, 1998. The effects of gap junction blockage on neuronal differentiation of human Ntera2/clone D1 cells. Exp Neurol 156: 16-32.
7. BANI-YAGHOUB M, UNDERHILL TM, NAUS CCG, 1999. Gap junction blockage interferes with neuronal and astroglial differentiation of mouse P19 embryonal carcinoma cells. Dev Genet 24: 69-81.
8. BATTER DK, CORPINA RA, ROY C, SPRAY DC, HERTZBERG EL, KESSLER JA, 1992. Heterogeneity in gap junction expression in astrocytes cultured from different brain regions. Glia 6: 213-221.
9. BELLIVEAU DJ, NAUS CCG, 1994. Cortical type 2 astrocytes are not dye coupled nor do they express the major gap junction genes found in the central nervous system. Glia 12: 24-34.
10. BELLIVEAU DJ, NAUS CCG, 1995. Differential localization of gap junction mRNAs in developing rat brain. Dev Neurosci 17: 81-96.
11. BELLIVEAU DJ, KIDDER GM, NAUS CCG, 1991. Expression of gap junction genes during postnatal neural development. Dev Genet 12: 308-317.
12. BELLIVEAU DJ, BECHBERGER JF, ROGERS KA, NAUS CCG, 1997. Differential expression of gap junctions in neurons and astrocytes derived from P19 embryonal carcinoma cells. Dev Genet 21: 187-200.
13. BENNETT MVL, 1997. Gap junctions as electrical synapses. J Neurocytol 26: 349-366.
14. BERGOFFEN J, SCHERER SS, WANG S, ORONZI SCOTT M, BONE LJ, PAUL DL, CHEN K, LENSCH MW, CHANCE PF, FISHBECK KH, 1993. Connexin mutations in X-linked Charcot-Marie-Tooth disease. Science 262: 2039-2042.
15. BINMOLLER FJ, MULLER CM, 1992. Postnatal development of dye-coupling among astrocytes in rat visual cortex. Glia 6: 127-137.
16. BITTMAN K, OWENS DF, KRIEGSTEIN AR, LOTURCO JJ, 1997. Cell coupling and uncoupling in the ventricular zone of the developing neocortex. J Neurosci 17: 7037-7044.
17. BRUZZONE R, RESSOT C, 1997. Connexins, gap junctions and cell-cell signalling in the nervous system. Eur J Neurosci 9: 1-6.
18. BRUZZONE R, HAEFLIGER JA, GIMLICH RL, PAUL DL, 1993. Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Mol Biol Cell 4: 7-20.
19. BRUZZONE R, WHITE TW, SCHERER SS, FISCHBECK KH, PAUL DL, 1994. Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron 13: 1253-1260.
20. BRUZZONE R, WHITE TW, PAUL DL, 1996. Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem 238: 1-27.
21. CAVENEY S, 1985. The role of gap junctions in development. Annu Rev Physiol 47: 319-335.
22. CAVINESS VSJ, WILLIAMS RS, 1984. Cellular patterns in developmental malformations of neocortex: neuron-glia interactions. In: Anima M, Suzuki Y, Yabnuchi H, eds. Developing Brain and its Disorders. Tokyo, Karger. 43-67.
23. CEPEDA C, WALSH JP, PEACOCK W, BUCHWALD NA, LEVINE MS, 1993. Dye-coupling in human neocortical tissue resected from children with intractable epilepsy. Cereb Cortex 3: 95-107.
24. CHARLES AC, 1994. Glia-neuron intercellular calcium signaling. Dev Neurosci 16: 196-206.
25. CHARLES AC, MERRILL JE, DIRKSEN ER, SANDERSON MJ, 1991. Intercellular signaling in glial cells: calcium waves and oscillations in response to mechanical stimulation and glutamate. Neuron 6: 983-992.
26. CHARLES AC, DIRKSEN ER, MERRILL JE, SANDERSON MJ, 1993. Mechanisms of intercellular calcium signaling in glial cells studied with dantrolene and thapsigargin. Glia 7: 134-145.
27. CHIU SY, KRIEGLER S, 1994. Neurotransmitter-mediated signaling between axons and glial cells. Glia 11: 191-200.
28. CONDORELLI DF, PARENTI R, SPINELLA F, SALINARO AT, BELLUARDO N, CARDILE V, CICIRATA F, 1998. Cloning of a new gap junction gene (cx36) highly expressed in mammalian brain neurons. Eur J Neurosci 10: 1202-1208.
29. CONNORS BW, BENARDO LS, PRINCE DA, 1983. Coupling between neurons of the developing rat neocortex. J Neurosci 3: 773-782.
30. COOK JE, BECKER DL, 1995. Gap junctions in the vertebrate retina. Microsc Res Tech 31: 408-419.
31. CORNELL-BELL AH, FINKBEINER SM, COOPER MS, SMITH SJ, 1990. Glutamate induces calcium waves in cultured astrocytes: long-range glial signalling. Science 247: 470-473.
32. DAHL E, MANTHEY D, CHEN Y, SCHWARZ HJ, CHANG YS, LALLEY PA, NICHOLSON BJ, WILLECKE K, 1996. Molecular cloning and functional expression of mouse connexin-30, a gap junction gene highly expressed in adult brain and skin. J Biol Chem 271: 17,903-17,910.
33. DAHL E, WILLECKE K, BALLING R, 1997. Segment-specific expression of the gap junction gene connexin31 during hindbrain development. Dev Genes Evol 207: 359-361.
34. DANI JW, SMITH SJ, 1995. The triggering of astrocytic calcium waves by NMDA-induced neuronal activation. In: Ciba Foundations Symposium, ed. Calcium Waves, Gradients and Oscillations. Chichester, Wiley. 195-209.
35. DERMIETZEL R, 1996. Molecular diversity and plasticity of gap junctions in the nervous system. In: Spray DC, Dermietzel R, eds. Gap Junctions in the Nervous System. Austin, RG Landes. 13-38.
36. DERMIETZEL R, SPRAY DC, 1993. Gap junctions in the brain: where, what type, how many and why? Trends Neurosci 16: 186-192.
37. DERMIETZEL R, SCHUNKE D, LEIBSTEIN A, 1978. The oligodendrocytic junctional complex. Cell Tissue Res 193: 61-72.
38. DERMIETZEL R, TRAUB O, HWANG TK, BEYER E, BENNETT MV, SPRAY DC, WILLECKE K, 1989. Differential expression of three gap junction proteins in developing and mature brain tissues. Proc Natl Acad Sci USA 86: 10, 148-10,152.
39. DERMIETZEL R, HERTBERG EL, KESSLER JA, SPRAY DC, 1991. Gap junctions between cultured astrocytes: immunocytochemical, molecular, and electrophysiological analysis. J Neurosci 11: 1421-1432.
40. DERMIETZEL R, KIRCHHOFF F, DICHTER B, KREMER M, 1995. Application of patch recordings from brain slice preparations for single cell detection of connexin gene transcripts. Proceedings of the 1995 Gap Junction Conference, Ile des Embiez, France
41. DUDEK FE, SNOW RW, TAYLOR CP, 1986. Role of electrical interactions in synchronization of epileptiform bursts. Adv Neurol 44: 593-617.
42. ENKVIST MO, MCCARTHY KD, 1992. Activation of protein kinase C blocks astroglial gap junction communication and inhibits the spread of calcium waves. J Neurochem 59: 519-526.
43. + concentration. J Neurochem 62: 489-495.
44. EWART JL, COHEN MF, MEYER RA, HUANG GY, WESSELS A, GOURDIE RG, CHIN AJ, PARK SMJ, LAZATIN BO, VILLABON S, Lo CW, 1997. Heart and neural tube defects in transgenic mice overexpressing the cx43 gap junction gene. Development 124: 1281-1292.
45. FISCHER G, KETTENMANN H, 1985. Cultured astrocytes form a syncytium after maturation. Exp Cell Res 159: 273-279.
46. FRASER SE, GREEN CR, BODE HR, GILULA NB, 1987. Selective disruption of gap junctional communication interferes with a patterning process in hydra. Science 237: 49-55.
47. FULTON BP, 1995. Gap junctions in the developing nervous system. Perspect Dev Neurobiol 2: 327-334.
48. FURSHPAN EJ, POTTER DD, 1959. Transmission at the giant motor synapses of the crayfish. J Physiol (Lond) 145: 289-325.
49. FUSHIKI S, KINOSHITA C, 1995. Spatial and temporal patterns of distribution of the gap junction protein connexin32 and 43 during histogenesis of mouse cerebral cortex. In: Kanno Y, Kataoka K, Shiba Y, Shibata Y, Shimazu T, eds. Progress on Cell Research, Vol 4, Intercellular Communication through Gap Junctions. Amsterdam, Elsevier. 239-243.
50. FUSHIKI S, BECHBERGER JF, NAUS CCG, 1997. Disruption of neuronal migration in neocortex of connexin43 null mutant mice. Soc Neurosci Abst 23: 870.
51. GIAUME C, 1994. Noradrenergic control of gap junction permeability in cultured striatal astrocytes. In: Briley M, Marien M, eds Noradrenergic Mechanisms in Parkinson's Disease. Boca Raton, CRC Press. 205-224.
52. GIAUME C, VENANCE L, 1995. Gap junctions in brain glial cells and development. Perspect Dev Neurobiol 2: 335-345.
53. GIAUME C, FROMAGET C, EL AOUMARI A, CORDIER J, GLOWINSKI J, GROS D, 1991a. Gap junctions in cultured astrocytes: single-channel currents and characterization of channel-forming protein. Neuron 6: 133-143.
54. GIAUME C, MARIN P, CORDIER J, GLOWINSKI J, PREMONT J, 1991b. Adrenergic regulation of intercellular communications between cultured striatal astrocytes from the mouse. Proc Natl Acad Sci USA 88: 5577-5581.
55. GIAUME C, CORDIER J, GLOWINSKI J, 1992. Endothelins inhibit junctional permeability in cultured mouse astrocytes. Eur J Neurosci 4: 877-881.
56. GOLDBERG GS, LAMPE PD, SHEEDY D, STEWART CC, NICHOLSON BJ, NAUS CCG, 1998. Direct isolation and analysis of endogenous transjunctional ADP from Cx43 transfected C6 glioma cells. Exp Cell Res 239: 82-92.
57. GOODENOUGH DA, GOLIGER JA, PAUL DL, 1996. Gap junctions, connexin, intercellular communication. Ann Rev Biochem 65: 475-502.
58. GOODENOUGH DA, SIMON A, PAUL DL, 1997. Cardiac conduction abnormalities in mice lacking connexin40. Mol Biol Cell 8: 124a.
59. GOTO T, TAKAHASHI T, MIYAMA S, BHIDE PG, CAVINESS VS, 1997. The effect of a gap junction uncoupling agent, 1-octanol, on cell cycle in vitro in the neocortical proliferative epithelium of embyronic mice. Soc Neurosci Abstr 23: 867.
60. HAEFLIGER J, BRUZZONE R, JENKINS NA, GILBERT DJ, COPELAND NG, PAUL DL, 1992. Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression and chromosome mapping. J Biol Chem 267: 2057-2064.
61. HOUGHTON FD, KIDDER GM, NAUS CCG, THONNISSEN E, WILLECKE K, WINTERHAGER E, 1998. Compensation between connexins 32 and 43 cannot explain the normal development of many organs in the absence of either connexin: analysis of fetuses lacking both connexins. Dev Genet in press.
62. JACOBSON M, 1991. Developmental Neurobiology. New York, Plenum Press.
63. JEFFERYS JGR, 1995. Nonsynaptic modulation of neuronal activity in the brain: electric currents and extracellular ions. Physiol Rev 75: 689-723.
64. JENSEN AM, CHIU S, 1993. Astrocyte networks. In: Murphy S, ed. Astrocytes: Pharmacology and Function. New York, Academic Press. 309-329.
65. JONES-VILLENEUVE EMV, MCBURNEY MW, ROGERS KA, KALNINS VI, 1982. Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J Cell Biol 94: 253-262.
66. KALIMI GH, Lo CW, 1989. Gap junctional communication in the extraembryonic tissues of gastulating mouse embryo. J Cell Biol 109: 3015-3026.
67. KANDLER K, 1997. Coordination of neuronal activity by gap junctions in the developing neocortex. Semin Cell Dev Biol 8: 43-51.
68. KANDLER K, KATZ LC, 1995. Neuronal coupling and uncoupling in the developing nervous system. Curr Opin Neurobiol 5: 98-105.
69. KANDLER K, KATZ LC, 1998. Coordination of neuronal activity in developing visual cortex by gap junction-mediated biochemical communication. J Neurosci 18: 1419-1427.
70. KELSELL DP, DUNLOP J, STEVENS HP, LENCH NJ, LIANG JN, PARRY G, MUELLER RF, LEIGH IM, 1997. Connexin 26 mutations in hereditary non-syndromic sensorineural deafness. Nature 387: 80-83.
71. KIKUCHI T, KIMURA RS, PAUL DL, ADAMS JC, 1995. Gap junctions in the rat cochlea: immunohistochemical and ultrastructural analysis. Anat Embryol 191: 101-118.
72. KIMELBERG HK, 1995. Receptors on astrocytes - what possible functions? Neurochem Int 26: 27-40.
73. KONIETZKO U, MULLER CM, 1994. Astrocytic dye coupling in rat hippocampus: topography, developmental onset, and modulation by protein kinase C. Hippocampus 4: 297-306.
74. KUNZELMANN P, BLUMCKE I, TRAUB O, DERMIETZEL R, WILLECKE K, 1997. Coexpression of connexin45 and -32 in oligodendrocytes of rat brain. J Neurocytol 26: 17-22.
75. LEE S, GILULA NB, WARNER AE, 1987. Gap junctional communication and compaction during preimplantation stages of mouse development. Cell 51: 851-860.
76. LEE SH, KIM WT, CORNELLBELL AH, SONTHEIMER H, 1994. Astrocytes exhibit regional specificity in gap-junction coupling. GLIA 11: 315-325.
77. Li J, HERTZBERG EL, NAGY JI, 1997. Connexin32 in oligodendrocytes and association with myelinated fibers in mouse and rat brain. J Comp Neurol 379: 571-591.
78. Lo TURCO JJ, KRIEGSTEIN AR, 1991. Clusters of coupled neuroblasts in embryonic neocortex. Science 252: 563-566.
79. LOEWENSTEIN WR, 1987. The cell-to-cell channel of gap junctions. Cell 48: 725-726.
80. MACVICAR BA, JAHNSEN H, 1985. Uncoupling of CA3 pyramidal neurons by propionate. Brain Res 330: 141-145.
81. MANTZ J, CORDIER J, GIAUME C, 1993. Effects of general anesthetics on intercellular communications mediated by gap junctions between astrocytes in primary culture. Anesthesiology 78: 892-901.
82. MARTINEZ S, GEIJO E, SANCHEZ-VIVES MV, PUELLES L, GALLEGO R, 1992. Reduced junctional permeability at interrhombomeric boundaries. Development 116: 1069-1076.
83. MATESIC DF, GERMAK JA, DUPONT E, MADHUKAR BV, 1993. Immortalized hypothalamic luteinizing hormone-releasing hormone neurons express a connexin 26-like protein and display functional gap junction coupling assayed by fluorescence recovery after photobleaching. Neuroendocrinology 58: 485-492.
84. MATSUMOTO A, ARAI Y, URANO A, HYODO S, 1991. Cellular localization of gap junction mRNA in the neonatal rat brain. Neurosci Lett 124: 225-228.
85. MICEVYCH PE, ABELSON L, 1991. Distribution of mRNAs coding for liver and heart gap junction proteins in the rat central nervous system. J Comp Neurol 305: 96-118.
86. MILLS SL, MASSEY SC, 1995. Differential properties of two gap junctional pathways made by All amacrine cells. Nature 377: 734-737.
87. MOSHE SL, ALBALA BJ, ACKERMANN RF, ENGEL J, 1983. Increased seizure susceptibility of the immature brain. Dev Brain Res 7: 81-85.
88. MUGNAINI E, 1986. Cell junctions of astrocytes, ependyma, and related cells in the mammalian central nervous system, with emphasis on the hypothesis of a generalized functional syncytium of supporting cells. In: Federoff S, Vernadakis A, eds. Development, Morphology, and Regional Specialization of Astrocytes, Vol. I. Orlando, FL, Academic Press. 329-371.
89. NADARAJAH B, THOMAIDOU D, EVANS WH, PARNAVELAS JG, 1996. Gap junctions in the adult cerebral cortex: regional differences in their distribution and cellular expression. J Comp Neurol 376: 326-342.
90. NADARAJAH B, JONES AM, EVANS WH, PARNAVELAS JG, 1997. Differential expression of connexins during neocortical development and neuronal circuit formation. J Neurosci 17: 3096-3111.
91. NAGY JI, YAMAMOTO T, SHIOSAKA S, DEWAR K, WHITTAKER M, HERTZBERG EL, 1988. Immunohistochemical localization of gap junction protein in rat CNS: a preliminary account. In: Hertzberg EL, Johnson RG, eds. Modern Cell Biology, Vol. 7: Gap Junctions. New York, Alan R. Liss. 375-389.
92. NAGY JI, OCHALSKI PAY, Li J, HERTZBERG EL, 1997. Evidence for the co-localization of another connexin with connexin-43 at astrocytic gap junctions in rat brain. Neuroscience 78: 533-548.
93. NAUS CC, BECHBERGER JF, CAVENEY S, WILSON JX, 1991a. Expression of gap junction genes in astrocytes and C6 glioma cells. Neurosci Lett 126: 33-36.
94. NAUS CC, BECHBERGER JF, PAUL DL, 1991b. Gap junction gene expression in human seizure disorder. Exp Neurol 111: 198-203.
95. NAUS CCG, BECHBERGER JF, ZHANG YC, VENANCE L, YAMASAKI H, JUNEJA SC, KIDDER GM, GIAUME C, 1997. Altered gap junctional communication, intercellular signaling and growth in cultured astrocytes deficient in connexin43. J Neurosci Res 49: 528-540.
96. NEDERGAARD M, 1994. Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science 263: 1768-1771.
97. NICHOLSON SM, BRUZZONE R, 1997. Gap junctions - getting the message through. Curr Biol 7: R340-R344.
98. O'BRIEN J, AL-UBAIDI MR, RIPPS H, 1996. Connexin 35: a gap-junctional protein expressed preferentially in the skate retina. Mol Biol Cell 7: 233-243.
99. O'BRIEN J, BRUZZONE R, WHITE TW, AL-UBAIDI AR, RIPPS H, 1998. Cloning and expression of two related connexins from the perch retina define a distinct subgroup of the connexin family. J Neurosci 18: 7625-7637.
100. OMORI Y, MESNIL M, YAMASAKI H, 1996. Connexin 32 mutations from X-linked Charcot-Marie-Tooth disease patients: functional defects and dominant negative effects. Mol Biol Cell 7: 907-916.
101. PAUL DL, 1995. New functions for gap junctions. Curr Opin Cell Biol 7: 665-672.
102. PAUL DL, YU K, BRUZZONE R, GIMLICH RL, GOODENOUGH DA, 1995. Expression of a dominant negative inhibitor of intercellular communication in the early Xenopus embryo causes delamination and extrusion of cells. Development 121: 371-381.
103. PEINADO A, YUSTE R, KATZ LC, 1993a. Extensive dye coupling between rat neocortical neurons during the period of circuit formation. Neuron 10: 103-114.
104. PEINADO A, YUSTE R, KATZ LC, 1993b. Gap junctional communication and the development of local circuits in neocortex. Cereb Cortex 3: 488-498.
105. PEPPER MS, MONTESANO R, EL AOUMARI A, GROS D, ORCI L, MEDA P, 1992. Coupling and connexin 43 expression in microvascular and large vessel endothelial cells. Am J Physiol 262: C1246-C1257.
106. PEREZ-VELAZQUEZ JL, VALIANTE TA, CARLEN PL, 1994. Modulation of gap junctional mechanisms during calciumfree induced field burst activity: a possible role for electrotonic coupling in epileptogenesis. J Neurosci 14: 4308-4317.
107. PEREZ VELAZQUEZ JL, FRANTSEVA M, NAUS CCG, BECHBERGER JF, JUNEJA SC, VELUMIAN A, CARLEN PL, KIDDER GM, MILLS LR, 1996. Development of astrocytes and neurons in cultured brain slices from mice lacking connexin43. Dev Brain Res 97: 293-296.
108. PLEASURE SJ, PAGE C, LEE VM, 1992. Pure, postmitotic, polarized human neurons derived from Ntera2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J Neurosci 12: 1802-1815.
109. RAKIC P, 1984. Defective cell-to-cell interactions as causes of brain malformations. In: Gallin ES, ed. Malformation of Development: Biological and Psychological Sources and Consequences. City, Academic Press. 239-285.
110. RAYPORT SG, KANDEL ER, 1981. Epileptogenic agents enhance transmission at an identified weak electrical synapse in Aplysia. Science 213: 462-464.
111. REAUME AG, DE SOUSA PA, KULKARNI S, LANGILLE BL, ZHU D, DAVIES TC, JUNEJA SC, KIDDER GM, ROSSANT J, 1995. Cardiac malformation in neonatal mice lacking connexin43. Science 267: 1831-1834.
112. REED KE, WESTPHALE EM, LARSON DM, WANG H-Z, VEENSTRA RD, BEYER EC, 1993. Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. J Clin Invest 91: 997-1004.
113. ROZENTAL R, SPRAY DC, 1996. Temporal expression of gap junctions during neuronal ontogeny. In: Spray DC, Dermietzel R, eds. Gap Junctions in the Nervous System. Austin, RG Landes. 261-277.
114. ROZENTAL R, MEHLER MF, MORALES M, ANDRADEROZENTAL AF, KESSLER JA, SPRAY DC, 1995a. Differentiation of hippocampal progenitor cells in vitro: temporal expression of intercellular coupling and voltage- and ligand-gated responses. Dev Biol 167: 350-362.
115. ROZENTAL R, URBAN M, FISHMAN GI, CHIU FC, EVES EM, ROSNER MR, KESSLER JA, SPRAY DC, 1995b. Gap junction down-regulation is required for neuronal differentiation. Soc Neurosci Abstr 21: 2000.
116. SHIOSAKA S, YAMAMOTO T, HERTZBERG EL, NAGY JI, 1989. Gap junction protein in rat hippocampus: correlative light and electron microscope immunohistochemical localization. J Comp Neurol 281: 282-297.
117. SIMBURGER E, STANG A, KREMER M, DERMIETZEL R, 1997. Expression of connexin43 mrna in adult rodent brain. Histochem Cell Biol 107: 127-137.
118. SIMON AM, GOODENOUGH DA, LI E, PAUL DL, 1997. Female infertility in mice lacking connexin 37. Nature 385: 525-529.
119. SOHL G, DEGEN J, TEUBNER B, WILLECKE K, 1998. The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development. FEBS Lett 428: 27-31.
120. SONTHEIMER H, MINTURN JE, BLACK JA, WAXMAN SG, RANSOM BR, 1990. Specificity of cell-cell coupling in rat optic nerve astrocytes in vitro. Proc Natl Acad Sci USA 87: 9833-9837.
121. SPRAY DC, MORENO AP, KESSLER JA, DERMIETZEL R, 1991. Characterization of gap junctions between cultured leptomeningeal cells. Brain Res 568: 1-14.
122. SPRAY DC, DERMIETZEL R, 1995. X-linked dominant Charcot-Marie-Tooth disease and other potential gapjunction diseases of the nervous system. Trends Neurosci 18: 256-262.
123. SUTER U, SNIPES GJ, 1995. Biology and genetics of hereditary motor and sensory neuropathies. Annu Rev Neurosci 18: 45-75.
124. VENANCE L, PIOMELLI D, GLOWINSKI J, GIAUME C, 1995. Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. Nature 376: 590-594.
125. VUKELIC JI, YAMAMOTO T, HERTZBERG EL, NAGY JI, 1991. Depletion of connexin43-immunoreactivity in astrocytes after kainic acid-induced lesions in rat brain. Neurosci Lett 130: 120-124.
126. WALZ W, HERTZ L, 1983. Functional interactions between neurons and astrocytes. II. Potassium homeostasis at the cellular level. Prog Neurobiol 20: 133-183.
127. WARNER A, 1992. Gap junctions in development-a perspective. Semin Cell Biol 3: 81-91.
128. WILLECKE K, HEYNKES R, DAHL E, STUTENKEMPER R, HENNEMANN H, JUNGBLUTH S, SUCHYNA T, NICHOLSON BJ, 1991. Mouse connexin37: cloning and functional expression of a gap junction gene highly expressed in lung. J Cell Biol 114: 1049-1057.
129. WOLSZON LR, GAO WQ, PASSANI MB, MACAGNO ER, 1994. Growth cone 'collapse' in vivo: are inhibitory interactions mediated by gap junctions? J Neurosci 14: 999-1010.
130. WOLSZON LR, PASSANI MB, MACAGNO ER, 1995. Interactions during a critical period inhibit bilateral projections in embryonic neurons. J Neurosci 15: 1506-1515.
131. WONG ROL, CHERNJAVSKY A, SMITH SJ, SHATZ CJ, 1995. Early functional neural networks in the developing retina. Nature 374: 716-718.
132. YAMAMOTO T, OCHALSKI A, HERTZBERG EL, NAGY JI, 1990. LM and EM immunolocalization of the gap junctional protein connexin 43 in rat brain. Brain Res 508: 313-319.
133. YAMAMOTO T, VUKELIC J, HERTZBERG EL, NAGY JI, 1992. Differential anatomical and cellular patterns of connexin43 expression during postnatal development of rat brain. Brain Res Dev Brain Res 66: 165-180.
134. YUSTE R, PEINADO A, KATZ LC, 1992. Neuronal domains in developing neocortex. Science 257: 665-669.
135. ZELANTE L, GASPARINI P, ESTIVILL X, MELCHIONDA S, DAGRUMA L, GOVEA N, MILA M, DELLAMONICA M, LUTFI J, SHOHAT M, MANSFIELD E, DELGROSSO K, RAPPAPORT E, SURREY S, FORTINA P, 1997. Connexin26 mutations associated with the most common form of non-syndromic neurosensory autosomal recessive deafness (DFNB1) in mediterraneans. Hum Mol Genet 6: 1605-1609.
136. ZHENG X, FRIEDMAN L, FAN D, ZHANG L, ARONICA E, HALL DH, DERMIETZEL R, BENNETT MVL, 1995. Connexin40 mRNA in astroctyes and neurons of rat brain. Soc Neurosci Abst 21: 563.