A compartment model to calculate time-dependent concentration profiles of topically applied chemical compounds in the anterior compartments of the rabbit eye

Alternatives to Laboratory Animals

Volumn 29, Issue 3, 2001, Pages 347-365

  Pospisil, H ^a   Holzhutter H G ^a  

^a Institute of Chemistry/Biochemistry   (Germany)

Author keywords

Alternative methods; Compartment model; Draize eye irritation test; Mathematical modelling; Regression analysis

Indexed keywords

ANIMAL TISSUE; ARTICLE; CELL MEMBRANE TRANSPORT; COMPARTMENT MODEL; CONCENTRATION RESPONSE; CORNEA ENDOTHELIUM; CORNEA EPITHELIUM; CORNEA STROMA; EYE TOXICITY; NONHUMAN; PRIORITY JOURNAL; RABBIT; REGRESSION ANALYSIS; TOXICITY TESTING; TOXICOKINETICS;

EID: 0034978842     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290102900318     Document Type: Article

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