Ocular absorption of Pz-peptide and its effect on the ocular and systemic pharmacokinetics of topically applied drugs in the rabbit

Pharmaceutical Research

Volumn 15, Issue 12, 1998, Pages 1882-1887

  Chung, Youn Bok ^a   Han, Kun ^a   Nishiura, Akio ^b,c   Lee, Vincent H L ^b  

^a Chungbuk National University   (South Korea)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c ONO PHARMACEUTICAL CO   (Japan)

Author keywords

Conjunctiva; Cornea; Hydrophilic solutes; Paracellular transport; Pz peptide

Indexed keywords

4 PHENYLAZOBENZYLOXYCARBONYLPROLYLLEUCYLGLYCYLPROLYL DEXTRO ARGININE; ATENOLOL; PROPRANOLOL; PZ PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CORNEA EPITHELIUM; DRUG ABSORPTION; DRUG EFFECT; DRUG PENETRATION; HYDROPHILICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; TOPICAL DRUG ADMINISTRATION;

ACTINS; ADMINISTRATION, TOPICAL; ANIMALS; ATENOLOL; BIOLOGICAL TRANSPORT; CALCIUM; CHELATING AGENTS; CONJUNCTIVA; CORNEA; CYTOCHALASIN B; EGTAZIC ACID; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; MALE; OLIGOPEPTIDES; PROPRANOLOL; RABBITS; SYMPATHOLYTICS; TIGHT JUNCTIONS;

EID: 0344629343     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011914324720     Document Type: Article

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