Maternal exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring in late puberty

Archives of Toxicology

Volumn 78, Issue 8, 2004, Pages 467-476

  Abdel Rahman, Ali ^a   Dechkovskaia, Anjelika M ^a   Mehta Simmons, Heena ^a   Sutton, Jazmine M ^a   Guan, Xiangrong ^a   Khan, Wasiuddin A ^a   Abou Donia, Mohamed B ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Acetylcholinesterase; Brainstem; Cerebellum; Chlorpyrifos; Co exposure; Gestational; Glial fibrillary acidic protein; Maternal; Neurotoxicity; Nicotine; Nicotinic acetylcholine receptor; Smoking

Indexed keywords

ACETYLCHOLINESTERASE; ALCOHOL; CHLORPYRIFOS; CHOLINESTERASE; GLIAL FIBRILLARY ACIDIC PROTEIN; NICOTINE; NICOTINIC RECEPTOR; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CELL SURVIVAL; CEREBELLUM; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; DENSITY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FEMALE; GESTATIONAL AGE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIGAND BINDING; MALE; NERVE CELL; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PUBERTY; RAT; STATISTICAL SIGNIFICANCE; WHITE MATTER;

ALKALOIDS; ANIMALS; AZOCINES; BUNGAROTOXINS; CEREBELLUM; CHLORPYRIFOS; CHOLINESTERASES; DRUG SYNERGISM; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; INSECTICIDES; MALE; NICOTINE; NICOTINIC AGONISTS; PARASYMPATHOLYTICS; PIRENZEPINE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; QUINOLIZINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; RECEPTORS, NICOTINIC; SEXUAL MATURATION;

ANIMALIA; VIOLA (ANGIOSPERM);

EID: 4544330378     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-004-0560-5     Document Type: Article

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