Novel associations between specific sperm morphological defects and leukocytospermia

Fertility and Sterility

Volumn 82, Issue 3, 2004, Pages 621-627

  Aziz, Nabil ^a   Agarwal, Ashok ^b   Lewis Jones, Iwan ^a   Sharma, Rakesh K ^b   Thomas Jr , Anthony J ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b Ctr for Adv Res in Hum Repro   (United States)

Author keywords

leukocytospermia; morphology; Semen; sperm deformity index; spermatozoa

Indexed keywords

ACROSOME; ADULT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; MORPHOLOGY; PRIORITY JOURNAL; REPRODUCTIVE HEALTH; SEMEN ANALYSIS; SPERMATOZOON MOTILITY; STANDARDIZATION; STATISTICAL ANALYSIS; TEACHING HOSPITAL;

ACROSOME; HUMANS; INFERTILITY, MALE; LEUKOCYTE COUNT; LEUKOCYTOSIS; MALE; SEMEN; SPERM MOTILITY; SPERM TAIL; SPERMATOZOA;

EID: 4544296066     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2004.02.112     Document Type: Article

References (37)

1. M.I.M. El-Demiry, T.B. Hargreave, A. Busuttil, R. Elton, K. James, G.D. Chisholm Immunocompetent cells in human testis in health and disease Fertil Steril 48 1987 470 479
2. H. Wolff The biologic significance of white blood cells in semen Fertil Steril 63 1995 1143 1157
3. Pudney JA, Anderson DJ. Organization of immunocompetent cells and their function in the male reproductive tract. In: Griffin PD, Johnson PM, eds. Local immunity in reproduction tract tissues. Oxford, United Kingdom: Oxford University Press, 1993.
4. A.A. Kiessling, N. Lamparelli, H.Z. Yin, M.M. Seibel, R.C. Eyre Semen leukocytes friends or foes? Fertil Steril 64 1995 196 198
5. M.J. Tomlinson, A. White, C.L. Barratt, A.E. Bolton, I.D. Cooke The removal of morphologically abnormal sperm forms by phagocytes: a positive role for seminal leucocytes Hum Reprod 7 1992 517 522
6. World Health Organization WHO laboratory manual for the examination of human sperm and sperm-cervical mucus interaction 4th ed 1999 Cambridge University Press New York
7. R. Sharma, F.F. Pasqualotto, D.R. Nelson, A.J. Thomas Jr, A. Agarwal Relationship between seminal white blood cell counts and oxidative stress in men treated at an infertility clinic J Androl 22 2001 575 583
8. J.G. Alvarez, R.K. Sharma, M. Ollero, R.A. Saleh, M.C. Lopez, A.J. Thomas Jr Increased DNA damage in sperm from leukocytospermic semen samples as determined by the sperm chromatin structure assay Fertil Steril 78 2002 319 329
9. R.A. Saleh, A. Agarwal, E. Kandirali, R.K. Sharma, A.J. Thomas Jr, E.A Nada Leukocytospermia is associated with increased reactive oxygen species production by human sperm Fertil Steril 78 2002 1215 1224
10. R.E. Berger, L.E. Karp, R.A. Williamson, J. Koehler, D.E. Moore, K.K. Holmes The relationship of pyospermia and seminal fluid bacteriology to sperm function as reflected in the sperm penetration assay Fertil Steril 37 1982 557 564
11. W. Eggert-Kruse, A. Bellmann, G. Rohr, W. Tilgen, B. Runnebaum Differentiation of round cells in semen by means of monoclonal antibodies and relationship with male fertility Fertil Steril 58 1992 1046 1055
12. G.F. Gonzales, G. Kortebani, A.B. Mazzoli Leucocytospermia and function of the seminal vesicles on seminal quality Fertil Steril 57 1992 1058 1065
13. E.H. Yanushpolsky, J.A. Politch, J.A. Hill, D.J. Anderson Is leukocytospermia clinically relevant? Fertil Steril 66 1996 822 825
14. J.F. Thomas, S.B. Fishel, J.A. Hall, S. Green, T.A. Newton, S.J. Thornton Increased polymorphonuclear granulocytes in seminal plasma in relation to sperm morphology Hum Reprod 12 1997 2418 2421
15. R. Menkveld, T.F. Kruger Sperm morphology and male urogenital infections Andrologia 30 1998 49 53
16. H.H. Van der Ven, R.S. Jeyendran, M. Perez-Palaez, S. Al-Hasani, K. Diedrich, D. Krebs Leucospermia in male infertility patients Eur J Obstet Gynaecol Reprod Biol 4 1987 49 52
17. J. Fedder, A.A. Askjaer, T. Hjort Non-spermatozoa cells in semen; relationship to other semen parameters and fertility status of the couple Arch Androl 31 1993 95 9103
18. C. Krausz, C. Mills, S. Rogers, S.L. Tan, R.J. Aitken Stimulation of oxidant generation by human sperm suspensions using phorbol esters and formyl peptides: relationships with motility and fertilization in vitro Fertil Steril 62 1994 599 605
19. Cohen PE, Pollard JW. Cytokines and growth factors in reproduction. In: Bronson R, ed. Reproductive immunology. Cambridge, MA: Blackwell Science, 1995.
20. M. Plante, E. de Lamirande, C. Gagnon Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility Fertil Steril 62 1994 387 393
21. R.J. Aitken, D. Buckingham, K. West, F.C. Wu, K. Zikopoulos, D.W. Richardson Differential contribution of leucocytes and spermatozoa to the generation of reactive oxygen species in the ejaculates of oligozoospermic patients and fertile donors J Reprod Fertil 94 1992 451 462
22. R.J. Aitken, D.W. Buckingham, J. Brindle, E. Gomez, H.W. Baker, D.S. Irvine Analysis of sperm movement in relation to the oxidative stress created by leukocytes in washed sperm preparations and seminal plasma Hum Reprod 10 1995 2061 2071
23. F.R. Ochsendorf Infections in the male genital tract and reactive oxygen species Hum Reprod Update 5 1999 399 420
24. T.F. Kruger, R. Menkveld, F.S.H. Stander, C.J. Lombard, J.P. Van der Merwe, J.A. Van Zyl Sperm morphologic features as a prognostic factor in in vitro fertilization Fertil Steril 46 1986 1118 1123
25. T.F. Kruger, A.A. Acosta, K.F. Simmons, R.J. Swanson, J.F. Matta, S. Oehninger Predictive value of abnormal sperm morphology in in vitro fertilization Fertil Steril 49 1988 112 117
26. N. Aziz, I. Buchan, C. Taylor, C.R. Kingsland, I. Lewis-Jones The sperm deformity index: a reliable predictor of the outcome of oocyte fertilization in vitro Fertil Steril 66 1996 1000 1008
27. M. Shekarriz, R.K. Sharma, A.J. Thomas Jr, A. Agarwal Positive myeloperoxidase staining (Endtz Test) as an indicator of excessive reactive oxygen species formation in semen J Assist Reprod Genet 12 1995 70 74
28. R. Eliasson Standards for investigation of human semen Andrologia 3 1971 49 64
29. E. Gil-Guzman, M. Ollero, M.C. Lopez, R.K. Sharma, J.G. Alvarez, A.J. Thomas Jr Differential production of reactive oxygen species by subsets of human spermatozoa at different stages of maturation Hum Reprod 16 2001 1922 1930
30. M. Ollero, E. Gil-Guzman, M.C. Lopez, R.K. Sharma, A. Agarwal, K Larson Characterizations of subsets of human spermatozoa at different stages of maturation: implications in the diagnosis and treatment of male infertility Hum Reprod 16 2001 1912 1921
31. P.A. In't Veld, F.J. Broekmans, H.F. de France, P.L. Pearson, M.H. Pieters, R.J. van Kooij Intracytoplasmic sperm injection (ICSI) and chromosomally abnormal spermatozoa Hum Reprod 12 1997 752 754
32. I. Lewis-Jones, N. Aziz, S. Seshadri, A. Douglas, P. Howard Sperm chromosomal abnormalities are linked to sperm morphological deformities Fertil Steril 79 2003 212 215
33. E. Gomez, D.W. Buckingham, J. Brindle, F. Lanzafame, D.S. Irvine, R.J. Aitken Development of an image analysis system to monitor the retention of residual cytoplasma by human spermatozoa: correlation with biochemical markers of the cytoplasmic space, oxidative stress, and sperm function J Androl 17 1996 276 287
34. G. Huszar, L. Vigue Correlation between the rate of lipid peroxidation and cellular maturity as measured by creatine kinase activity in human spermatozoa J Androl 15 1994 71 77
35. R.J. Aitken, M. Paterson, H. Fisher, D.W. Buckingham, M. van Duin Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function J Cell Sci 108 1995 2017 2025
36. R.J. Aitken, D.W. Buckingham, D. Harkiss, M. Paterson, H. Fisher, D.S. Irvine The extragenomic action of progesterone on human spermatozoa is influenced by redox regulated changes in tyrosine phosphorylation during capacitation Mol Cell Endocrinol 117 1996 83 93
37. F.H. Comhaire, A.M. Mahmoud, C.E. Depuydt, A.A. Zalata, A.B. Christophe Mechanisms and effects of male genital tract infection on sperm quality and fertilizing potential: the andrologist's viewpoint Hum Reprod Update 5 1999 393 398