Intragraft iNOS induction during human liver allograft rejection depresses cytochrome p450 activity

Transplant International

Volumn 17, Issue 7, 2004, Pages 370-378

  Westerholt, Alexandra ^a   Himpel, Sigrid ^b   Hager Gensch, Birgit ^b   Maier, Stefan ^a   Werner, Martin ^b   Stadler, Josef ^b   Doehmer, Johannes ^c   Heidecke, Claus Dieter ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c GenPharmTox BioTech AG   (Germany)

Author keywords

Aminopyrine breath test; Cytokine gene expression; Liver function; Liver transplantation; Nitric oxide

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; METHYLPREDNISOLONE; TACROLIMUS;

ACUTE GRAFT REJECTION; AMINOPHENAZONE BREATH TEST; ARTICLE; BREATH ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; INFLAMMATION; LIVER BIOPSY; LIVER DISEASE; LIVER FUNCTION; LIVER GRAFT; LIVER MICROSOME; MAJOR CLINICAL STUDY; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

AMINOPYRINE; BREATH TESTS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRAFT REJECTION; HUMANS; INTERFERON TYPE II; LIVER TRANSPLANTATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSPLANTATION, HOMOLOGOUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4544278694     PISSN: 09340874     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2004.tb00457.x     Document Type: Article

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