-
1
-
-
0030724591
-
Pathogenesis of type 2 diabetes: Metabolic and molecular implications for identifying diabetes genes
-
DeFronzo RA. Pathogenesis of type 2 diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev 1997; 5: 177-269
-
(1997)
Diabetes Rev
, vol.5
, pp. 177-269
-
-
DeFronzo, R.A.1
-
2
-
-
0030839435
-
GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes
-
Stenbit AE, Tsao T-S, Li J, Burcelin R, Geenen DL, Factor SM, Houseknecht K, Katz EB, Charron MJ. GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes. Nature Med 1997; 3: 1096-1101
-
(1997)
Nature Med
, vol.3
, pp. 1096-1101
-
-
Stenbit, A.E.1
Tsao, T.-S.2
Li, J.3
Burcelin, R.4
Geenen, D.L.5
Factor, S.M.6
Houseknecht, K.7
Katz, E.B.8
Charron, M.J.9
-
3
-
-
0031452437
-
The human hexokinase II gene promoter: Functional characterization and detection of variants among patients with NIDDM
-
Malkki M, Laakso M, Deeb SS. The human hexokinase II gene promoter: functional characterization and detection of variants among patients with NIDDM. Diabetologia 1997; 40: 1461-1469
-
(1997)
Diabetologia
, vol.40
, pp. 1461-1469
-
-
Malkki, M.1
Laakso, M.2
Deeb, S.S.3
-
4
-
-
0038321327
-
Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia inType 2 diabetes
-
Hojlund K, Stahr P, Hansen FB, Green AK, Hardie GD, Richter AK, Beck-Nielsen H, Wojtaszewski FPJ. Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia inType 2 diabetes. Diabetes 2003; 52: 1393-1402
-
(2003)
Diabetes
, vol.52
, pp. 1393-1402
-
-
Hojlund, K.1
Stahr, P.2
Hansen, F.B.3
Green, A.K.4
Hardie, G.D.5
Richter, A.K.6
Beck-Nielsen, H.7
Wojtaszewski, F.P.J.8
-
5
-
-
0026723385
-
Gene expression of GLUT4 in skeletal muscle from insulin-resistant patients with obesity, IGT, GDM, and NIDDM
-
Garvey WT, Maianu L, Hancock JA, Golichowski AM, Baron A. Gene expression of GLUT4 in skeletal muscle from insulin-resistant patients with obesity, IGT, GDM, and NIDDM. Diabetes 1992; 41: 465-475
-
(1992)
Diabetes
, vol.41
, pp. 465-475
-
-
Garvey, W.T.1
Maianu, L.2
Hancock, J.A.3
Golichowski, A.M.4
Baron, A.5
-
6
-
-
0028999677
-
Skeletal muscle GLUT4 protein concentration and aging in humans
-
Houmard JA, Weidner MD, Dolan PL, Leggett-Frazier N, Gavigan KE, Hickey MS, Tyndall GL, Zheng D, Alshami A, Dohm L. Skeletal muscle GLUT4 protein concentration and aging in humans. Diabetes 1995; 44: 555-560
-
(1995)
Diabetes
, vol.44
, pp. 555-560
-
-
Houmard, J.A.1
Weidner, M.D.2
Dolan, P.L.3
Leggett-Frazier, N.4
Gavigan, K.E.5
Hickey, M.S.6
Tyndall, G.L.7
Zheng, D.8
Alshami, A.9
Dohm, L.10
-
7
-
-
0032104120
-
Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance
-
Garvey WT, Maianu L, Zhu JH, Brechtel-Hook G, Wallace P, Baron AD. Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance. J Clin Invest 1998; 101: 2377-2386
-
(1998)
J Clin Invest
, vol.101
, pp. 2377-2386
-
-
Garvey, W.T.1
Maianu, L.2
Zhu, J.H.3
Brechtel-Hook, G.4
Wallace, P.5
Baron, A.D.6
-
9
-
-
0031750401
-
Regulation of skeletal muscle hexokinase II by insulin in nondiabetic and NIDDM subjects
-
Kruszynska YT, Mulford MI, Baloga J, Yu JG, Olefsky JM. Regulation of skeletal muscle hexokinase II by insulin in nondiabetic and NIDDM subjects. Diabetes 1998; 47: 1107-1113
-
(1998)
Diabetes
, vol.47
, pp. 1107-1113
-
-
Kruszynska, Y.T.1
Mulford, M.I.2
Baloga, J.3
Yu, J.G.4
Olefsky, J.M.5
-
10
-
-
0025522071
-
The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
-
Dent P, Lavoinne A, Nakielny S, Caudwell FB, Watt P, Cohen P. The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle. Nature 1990; 348: 302-308
-
(1990)
Nature
, vol.348
, pp. 302-308
-
-
Dent, P.1
Lavoinne, A.2
Nakielny, S.3
Caudwell, F.B.4
Watt, P.5
Cohen, P.6
-
11
-
-
0029742775
-
Hexosamines and insulin resistance
-
McClain DA, Crook ED. Hexosamines and insulin resistance. Diabetes 1996; 45: 1003-1009
-
(1996)
Diabetes
, vol.45
, pp. 1003-1009
-
-
McClain, D.A.1
Crook, E.D.2
-
12
-
-
0028967019
-
In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: Possible relevance to the maladaptive responses to chronic hyperglycemia
-
Giaccari A, Morviducci L, Zorretta D, Sbraccia P, Leonetti F, Caiola S, Buongiorno A, Bonadonna RC, Tamburrano G. In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: possible relevance to the maladaptive responses to chronic hyperglycemia. Diabetologia 1995; 38: 518-524
-
(1995)
Diabetologia
, vol.38
, pp. 518-524
-
-
Giaccari, A.1
Morviducci, L.2
Zorretta, D.3
Sbraccia, P.4
Leonetti, F.5
Caiola, S.6
Buongiorno, A.7
Bonadonna, R.C.8
Tamburrano, G.9
-
13
-
-
0030042488
-
Increased glutamine:fructose-6-phosphate amidotransferase activity in skeletal muscle of patients with NIDDM
-
Yki-Jårvinen H, Daniels MC, Virkamåki A, Måkimattila S, DeFronzo RA, McClain D. Increased glutamine:fructose-6-phosphate amidotransferase activity in skeletal muscle of patients with NIDDM. Diabetes 1996; 45: 302-307
-
(1996)
Diabetes
, vol.45
, pp. 302-307
-
-
Yki-Jårvinen, H.1
Daniels, M.C.2
Virkamåki, A.3
Måkimattila, S.4
DeFronzo, R.A.5
McClain, D.6
-
14
-
-
9544226451
-
Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance
-
Hebert LF, Jr, Daniels MC, Zhou J, Crook ED, Turner RL, Simmons ST, Neidigh JL, Zhu JS, Baron AD, McClain DA. Overexpression of glutamine:fructose- 6-phosphate amidotransferase in transgenic mice leads to insulin resistance. J Clin Invest 1996; 98: 930-936
-
(1996)
J Clin Invest
, vol.98
, pp. 930-936
-
-
Hebert Jr., L.F.1
Daniels, M.C.2
Zhou, J.3
Crook, E.D.4
Turner, R.L.5
Simmons, S.T.6
Neidigh, J.L.7
Zhu, J.S.8
Baron, A.D.9
McClain, D.A.10
-
15
-
-
0034650763
-
The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP
-
Ricquier D, Bouillaud F. The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP. Biochem J 2000; 345: 161-179
-
(2000)
Biochem J
, vol.345
, pp. 161-179
-
-
Ricquier, D.1
Bouillaud, F.2
-
16
-
-
0037397649
-
Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice
-
Horvath TL, Diano S, Miyamoto S, Barry S, Gatti S, Alberati D, Livak F, Lombardi A, Moreno M, Goglia F, Mor G, Hamilton J, Kachinskas D, Horwitz B, Warden CH. Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice. Int J Obesity 2003; 27: 433-442
-
(2003)
Int J Obesity
, vol.27
, pp. 433-442
-
-
Horvath, T.L.1
Diano, S.2
Miyamoto, S.3
Barry, S.4
Gatti, S.5
Alberati, D.6
Livak, F.7
Lombardi, A.8
Moreno, M.9
Goglia, F.10
Mor, G.11
Hamilton, J.12
Kachinskas, D.13
Horwitz, B.14
Warden, C.H.15
-
18
-
-
0014743725
-
General survey of diabetic features of yellow KK mice
-
Iwatsuka H, Shino A, Suzuoki Z. General survey of diabetic features of yellow KK mice. Endocrinol Jpn 1970; 17: 23-35
-
(1970)
Endocrinol Jpn
, vol.17
, pp. 23-35
-
-
Iwatsuka, H.1
Shino, A.2
Suzuoki, Z.3
-
19
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee G-H, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM. Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996; 379: 632-635
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.-H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
20
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
21
-
-
0018139377
-
Obese and diabetes: Two mutant genes causing diabetes - Obesity syndromes in mice
-
Coleman DL. Obese and diabetes: two mutant genes causing diabetes - obesity syndromes in mice. Diabetologia 1978; 14: 141-148
-
(1978)
Diabetologia
, vol.14
, pp. 141-148
-
-
Coleman, D.L.1
-
22
-
-
0014864488
-
Muscle fiber types: How many and what kind?
-
Brooke MH, Kaiser KK. Muscle fiber types: How many and what kind? Arch. Neurol 1970; 23: 369-379
-
(1970)
Arch Neurol
, vol.23
, pp. 369-379
-
-
Brooke, M.H.1
Kaiser, K.K.2
-
23
-
-
0032495996
-
Transcriptional regulation of muscle-specific genes during myoblast differentiation
-
Shimokawa T, Kato M, Ezaki O, Hashimoto S. Transcriptional regulation of muscle-specific genes during myoblast differentiation. Biochem Biophys Res Commun 1998; 246: 287-292
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 287-292
-
-
Shimokawa, T.1
Kato, M.2
Ezaki, O.3
Hashimoto, S.4
-
24
-
-
0030997893
-
The role of glucose 6-phosphate in the control of glycogen synthase
-
Villar-Palasi C, Guinovart JJ. The role of glucose 6-phosphate in the control of glycogen synthase. FASEB J 1997; 11: 544-558
-
(1997)
FASEB J
, vol.11
, pp. 544-558
-
-
Villar-Palasi, C.1
Guinovart, J.J.2
-
25
-
-
0029148426
-
Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4
-
Katz EB, Stenbit AE, Hatton K, DePinho R, Charron MJ. Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4. Nature 1995; 377: 151-155
-
(1995)
Nature
, vol.377
, pp. 151-155
-
-
Katz, E.B.1
Stenbit, A.E.2
Hatton, K.3
DePinho, R.4
Charron, M.J.5
-
26
-
-
0028817712
-
Overexpression of glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice
-
Ren JM, Marshall BA, Mueckler MM, McCaleb M, Amatruda JM, Shulman GI. Overexpression of glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice. J Clin Invest 1995; 95: 429-432
-
(1995)
J Clin Invest
, vol.95
, pp. 429-432
-
-
Ren, J.M.1
Marshall, B.A.2
Mueckler, M.M.3
McCaleb, M.4
Amatruda, J.M.5
Shulman, G.I.6
-
27
-
-
0030069588
-
Enhanced insulin action due to targeted glut4 overexpression exclusively in muscle
-
TsaoT-S, Burcelin R, Katz EB, Huang L, Charron MJ. Enhanced insulin action due to targeted glut4 overexpression exclusively in muscle. Diabetes 1996; 45: 28-36
-
(1996)
Diabetes
, vol.45
, pp. 28-36
-
-
Tsao, T.-S.1
Burcelin, R.2
Katz, E.B.3
Huang, L.4
Charron, M.J.5
-
28
-
-
0028947967
-
Skeletal muscle glucose transport and metabolism are enhanced in transgenic mice overexpressing the glut4 glucose transporter
-
Hansen PA, Gulve EA, Marshall BA, Gao J, Pessin JE, Holloszy JO, Mueckler M. Skeletal muscle glucose transport and metabolism are enhanced in transgenic mice overexpressing the glut4 glucose transporter. J Biol Chem 1995; 270: 1679-1684
-
(1995)
J Biol Chem
, vol.270
, pp. 1679-1684
-
-
Hansen, P.A.1
Gulve, E.A.2
Marshall, B.A.3
Gao, J.4
Pessin, J.E.5
Holloszy, J.O.6
Mueckler, M.7
-
29
-
-
0028942658
-
Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (Glut4)
-
Gibbs EM, Stock JL, McCoid SC, Stukenbrok HA, Pessin JE, Stevenson RW, Milici AJ, McNeish JD. Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (Glut4). J Clin Invest 1995; 95: 1512-1518
-
(1995)
J Clin Invest
, vol.95
, pp. 1512-1518
-
-
Gibbs, E.M.1
Stock, J.L.2
McCoid, S.C.3
Stukenbrok, H.A.4
Pessin, J.E.5
Stevenson, R.W.6
Milici, A.J.7
McNeish, J.D.8
-
30
-
-
0028356449
-
Glucose transport activity in skeletal muscles from transgenic mice overexpressing glut1
-
Gulve EA, Ren JM, Marchall BA, Gao J, Hansen PA, Holloszy JO, Mueckler M. Glucose transport activity in skeletal muscles from transgenic mice overexpressing glut1. J Biol Chem 1994; 269: 18 366-18 370
-
(1994)
J Biol Chem
, vol.269
, pp. 18366-18370
-
-
Gulve, E.A.1
Ren, J.M.2
Marchall, B.A.3
Gao, J.4
Hansen, P.A.5
Holloszy, J.O.6
Mueckler, M.7
-
31
-
-
0035029812
-
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue
-
Ducluzeau P-H, Perretti N, Laville M, Andreelli F, Vega N, Riou J-P, Vidal H. Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Diabetes 2001; 50: 1134-1142
-
(2001)
Diabetes
, vol.50
, pp. 1134-1142
-
-
Ducluzeau, P.-H.1
Perretti, N.2
Laville, M.3
Andreelli, F.4
Vega, N.5
Riou, J.-P.6
Vidal, H.7
-
32
-
-
0025694729
-
Effect of experimental diabetes on the activity of hexokinase isoenzymes in tissues of the rat
-
Sochor M, Baquer NZ, Hothersall JS, McLean P. Effect of experimental diabetes on the activity of hexokinase isoenzymes in tissues of the rat. Biochem Int 1990; 22: 467-474
-
(1990)
Biochem Int
, vol.22
, pp. 467-474
-
-
Sochor, M.1
Baquer, N.Z.2
Hothersall, J.S.3
McLean, P.4
-
33
-
-
0031938518
-
Expression of glutamine:fructose-6-phosphate amidotransferase in human tissues. Evidence for high variability and distinct regulation in diabetes
-
Nerlich AG, Sauer U, Kolm-Litty V, Wagner E, Koch M, Schleicher ED. Expression of glutamine:fructose-6-phosphate amidotransferase in human tissues. Evidence for high variability and distinct regulation in diabetes. Diabetes 1998; 47: 170-178
-
(1998)
Diabetes
, vol.47
, pp. 170-178
-
-
Nerlich, A.G.1
Sauer, U.2
Kolm-Litty, V.3
Wagner, E.4
Koch, M.5
Schleicher, E.D.6
-
34
-
-
0025781289
-
Coordinated regulation of glutamine:fructose-6-phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation
-
Traxinger RR, Marchall S. Coordinated regulation of glutamine:fructose-6- phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation. J Biol Chem 1991; 266: 10 148-10 154
-
(1991)
J Biol Chem
, vol.266
, pp. 10148-10154
-
-
Traxinger, R.R.1
Marchall, S.2
-
35
-
-
0030825308
-
Increased activity of the hexosamine synthesis pathway in muscles of insulin-resistant ob/ob mice
-
Buse MG, Robinson KA, Gettys TW, McMahon EG, Gulve EA. Increased activity of the hexosamine synthesis pathway in muscles of insulin-resistant ob/ob mice. Am J Physiol 1997; 272: E1080-E1088
-
(1997)
Am J Physiol
, vol.272
-
-
Buse, M.G.1
Robinson, K.A.2
Gettys, T.W.3
McMahon, E.G.4
Gulve, E.A.5
-
36
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mayo GG, Woolf EA, Monroe CA, Tepper RI. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995; 83: 1263-1271
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, S.12
Moriarty, A.13
Moore, K.J.14
Smutko, J.S.15
Mayo, G.G.16
Woolf, E.A.17
Monroe, C.A.18
Tepper, R.I.19
-
37
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen WJ, Baker MB, Hecht R, Winters D, Boone T, Collins F. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995; 269: 540-543
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, W.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
38
-
-
0032545711
-
Uncoupling protein-3: A muscle-specific gene upregulated by leptin in ob/ob mice
-
Liu Q, Bai C, Chen F, Wang R, MacDonald T, Gu M, Zhang W, Morsy MA, Caskey T. Uncoupling protein-3: a muscle-specific gene upregulated by leptin in ob/ob mice. Gene 1998; 207: 1-7
-
(1998)
Gene
, vol.207
, pp. 1-7
-
-
Liu, Q.1
Bai, C.2
Chen, F.3
Wang, R.4
MacDonald, T.5
Gu, M.6
Zhang, W.7
Morsy, M.A.8
Caskey, T.9
-
39
-
-
0030987368
-
Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation
-
Zhou Y-T, Shimabukuro M, Koyama K, Lee Y, Wang M-Y, Trieu F, Newgard CB, Unger RH. Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. Proc Natl Acad Sci USA 1997; 94: 6386-6390
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6386-6390
-
-
Zhou, Y.-T.1
Shimabukuro, M.2
Koyama, K.3
Lee, Y.4
Wang, M.-Y.5
Trieu, F.6
Newgard, C.B.7
Unger, R.H.8
-
40
-
-
0036875212
-
Divergent effects of leptin in mice susceptible or resistant to obesity
-
Takahashi N, Patel HR, Qi Y, Dushay J, Ahima RS. Divergent effects of leptin in mice susceptible or resistant to obesity. Horm Metab Res 2002; 34: 691-697
-
(2002)
Horm Metab Res
, vol.34
, pp. 691-697
-
-
Takahashi, N.1
Patel, H.R.2
Qi, Y.3
Dushay, J.4
Ahima, R.S.5
|