Ethanol and illicit drugs do not affect the diagnostic utility of base deficit and lactate in differentiating minor from major injury in trauma patients

Academic Emergency Medicine

Volumn 11, Issue 10, 2004, Pages 1014-1020

  Zehtabchi, Shahriar ^a   Baron, Bonny J ^a   Sinert, Richard ^a   Yadav, Kabir ^a   Lucchesi, Michael ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

base deficit; cocaine; ethanol; injuries; lactic acidosis; toxins; trauma

Indexed keywords

ALCOHOL; BASE; ILLICIT DRUG; LACTIC ACID;

ADULT; ALCOHOL BLOOD LEVEL; ARTICLE; BLOOD TRANSFUSION; BLUNT TRAUMA; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; FEMALE; HEMATOCRIT; HOSPITAL ADMISSION; HUMAN; INJURY; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PENETRATING TRAUMA; PRIORITY JOURNAL; URINALYSIS;

ACID-BASE IMBALANCE; ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; EMERGENCY MEDICINE; ETHANOL; FEMALE; HUMANS; INJURY SEVERITY SCORE; LACTIC ACID; MALE; MIDDLE AGED; NEW YORK; PROSPECTIVE STUDIES; SEX DISTRIBUTION; STREET DRUGS; WOUNDS AND INJURIES; WOUNDS, NONPENETRATING; WOUNDS, PENETRATING;

EID: 4544275828     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1197/j.aem.2004.06.008     Document Type: Article

References (29)

1. C.A. Soderstrom, R.W. DuPriest Jr., C. Benner, K. Maekawa, and R.A. Cowley Alcohol and roadway trauma: problems of diagnosis and management Am Surg 45 1979 129 136
2. P.D. Woolf, C. Cox, and J.V. McDonald Effects of intoxication on the catecholamine response to multisystem injury J Trauma 31 1991 1271 1275 discussion 5-6
3. J.E. Gruber, D. Bar-Or, J.A. Marx, E.E. Moore, and J.V. Winkler Protracted metabolic acidosis: the impact of acute ethanol in hemorrhagic shock J Emerg Med 10 1992 545 552
4. C.J. Bruce, D.H. Livingston, C.A. Schneider, P.A. Loder, and J.H. Siegel The effect of cocaine on the physiologic response to hemorrhagic shock Surgery 114 1993 429 434 discussion 34-5
5. T.C. Bania, B.J. Baron, G.L. Almond, P. Lucchesi, and T.M. Scalea The hemodynamic effects of cocaine during acute controlled hemorrhage in conscious rats J Toxicol Clin Toxicol 38 2000 1 6
6. F.E. Kuhn, M.N. Johnson, R.A. Gillis, M.S. Visner, and G.L. Schaer Effect of cocaine on the coronary circulation and systemic hemodynamics in dogs J Am Coll Cardiol 16 1990 1481 1491
7. B.D. Bertolet, G. Freund, C.A. Martin, D.L. Perchalski, C.M. Williams, and C.J. Pepine Unrecognized left ventricular dysfunction in an apparently healthy cocaine abuse population Clin Cardiol 13 1990 323 328
8. T.M. Scalea, H.M. Simon, and A.O. Duncan Geriatric blunt multiple trauma: improved survival with early invasive monitoring J Trauma 30 1990 129 134 discussion 34-6
9. B. Abou-Khalil, T.M. Scalea, S.Z. Trooskin, S.M. Henry, and R. Hitchcock Hemodynamic responses to shock in young trauma patients: need for invasive monitoring Crit Care Med 22 1994 633 639
10. J.W. Davis The relationship of base deficit to lactate in porcine hemorrhagic shock and resuscitation J Trauma 36 1994 168 172
11. J.W. Davis, R.C. Mackersie, T.L. Holbrook, and D.B. Hoyt Base deficit as an indicator of significant abdominal injury Ann Emerg Med 20 1991 842 844
12. J.W. Davis, S.N. Parks, K.L. Kaups, H.E. Gladen, and S. O'Donnell-Nicol Admission base deficit predicts transfusion requirements and risk of complications J Trauma 41 1996 769 774
13. E.J. Rutherford, J.A. Morris Jr., G.W. Reed, and K.S. Hall Base deficit stratifies mortality and determines therapy J Trauma 33 1992 417 423
14. J.W. Davis, K.L. Kaups, and S.N. Parks Base deficit is superior to pH in evaluating clearance of acidosis after traumatic shock J Trauma 44 1998 114 118
15. J.W. Davis, S.R. Shackford, and T.L. Holbrook Base deficit as a sensitive indicator of compensated shock and tissue oxygen utilization Surg Gynecol Obstet 173 1991 473 476
16. M.C. Chang, E.J. Rutherford, and J.A. Morris Jr. Base deficit as a guide to injury severity and volume resuscitation J Tenn Med Assoc 86 1993 59 61
17. E.H. Kincaid, P.R. Miller, J.W. Meredith, N. Rahman, and M.C. Chang Elevated arterial base deficit in trauma patients: a marker of impaired oxygen utilization J Am Coll Surg 187 1998 384 392
18. A. Lamminpää, J. Vilska, U.M. Korri, and V. Riihimaki Alcohol intoxication in hospitalized young teenagers Acta Paediatr 82 1993 783 788
19. R.K. Conlee, K.P. Kelly, E.O. Ojuka, and R.L. Hammer Cocaine and exercise: alpha-1 receptor blockade does not alter muscle glycogenolysis or blood lactacidosis J Appl Physiol 88 2000 77 81
20. R.A. Kreisberg, W.C. Owen, and A.M. Siegal Ethanol-induced hyperlacticacidemia: inhibition of lactate utilization J Clin Invest 50 1971 166 174
21. D.H. Han, K.P. Kelly, G.W. Fellingham, and R.K. Conlee Cocaine and exercise: temporal changes in plasma levels of catecholamines, lactate, glucose, and cocaine Am J Physiol 270 1996 E438 E444
22. J.A. Marques-Magallanes, S.N. Koyal, C.B. Cooper, E.C. Kleerup, and D.P. Tashkin Impact of habitual cocaine smoking on the physiologic response to maximum exercise Chest 112 1997 1008 1016
23. C.F. Richards, R.F. Clark, T. Holbrook, and D.B. Hoyt The effect of cocaine and amphetamines on vital signs in trauma patients J Emerg Med 13 1995 59 63
24. C.M. Dunham, L.A. Watson, and C. Cooper Base deficit level indicating major injury is increased with ethanol J Emerg Med 18 2000 165 171
25. K.L. Mattox, D.V. Feliciano, and E.E. Moore Trauma 4th ed. 1999 McGraw-Hill New York, NY
26. J.W. Davis, and K.L. Kaups Base deficit in the elderly: a marker of severe injury and death J Trauma 45 1998 873 877
27. J.W. Davis, K.L. Kaups, and S.N. Parks Effect of alcohol on the utility of base deficit in trauma J Trauma 43 1997 507 510
28. S.A. Signs, H.I. Dickey-White, V.W. Vanek, S. Perch, M.D. Schechter, and A.T. Kulics The formation of cocaethylene and clinical presentation of ED patients testing positive for the use of cocaine and ethanol Am J Emerg Med 14 1996 665 670
29. E.F. McCance-Katz, L.H. Price, C.J. McDougle, T.R. Kosten, J.E. Black, and P.I. Jatlow Concurrent cocaine-ethanol ingestion in humans: pharmacology, physiology, behavior, and the role of cocaethylene Psychopharmacology (Berl) 111 1993 39 46