Cocaine and exercise: Temporal changes in plasma levels of catecholamines, lactate, glucose, and cocaine

American Journal of Physiology - Endocrinology and Metabolism

Volumn 270, Issue 3 33-3, 1996, Pages

  Han, Dong H ^a   Patrick Kelly, K ^a   Fellingham, Gilbert W ^a   Conlee, Robert K ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

cocaine half life; epinephrine; norepinephrine

Indexed keywords

ADRENALIN; CATECHOLAMINE; COCAINE; GLUCOSE; LACTIC ACID; NORADRENALIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; EXERCISE; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT;

EID: 13344282092     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.270.3.e438     Document Type: Article

References (35)

1. Bracken, M. E., D. R. Bracken, A. G. Nelson, and R. K. Conlee. Effect of cocaine on exercise endurance and glycogen use in rats. J. Appl. Physiol. 64: 884-887, 1988.
2. Bracken, M. E., D. R. Bracken, W. W. Winder, and R. K. Conlee. Effect of various doses of cocaine on endurance capacity in rats. J. Appl. Physiol. 66: 377-383, 1989.
3. Braiden, R. W., G. W. Fellingham, and R. K. Conlee. Effects of cocaine on glycogen metabolism and endurance during high intensity exercise. Med. Sci. Sports Exercise 26: 695-700, 1994.
4. Branch, C. A., and M. M. Knuepfer. Adrenergic mechanisms underlying cardiac and vascular responses to cocaine in conscious rats. J. Pharmacol. Exp. Ther. 263: 742-751, 1992.
5. ++. J. Biol. Chem. 246: 1961-1967, 1971.
6. Chiueh, C. C., and I. J. Kopin. Centrally mediated release by cocaine of endogenous epinephrine and norepinephrine from the sympathoadrenal medullary system of unanesthetized rats. J. Pharmacol. Exp. Ther. 205: 148-154, 1978.
7. Christensen, N. J., and H. Galbo. Sympathetic nervous activity during exercise. Annu. Rev. Physiol. 45: 139-153, 1983.
8. Conlee, R. K., D. W. Barnett, K. P. Kelly, and D. H. Han. Effects of cocaine on plasma catecholamine and muscle glycogen concentrations during exercise in the rat. J. Appl. Physiol. 70: 1323-1327, 1991.
9. Conlee, R. K., D. W. Barnett, K. P. Kelly, and D. H. Han. Effects of cocaine, exercise, and resting conditions on plasma corticosterone and catecholamine concentrations in the rat. Metab. Clin. Exp. 40: 1043-1047, 1991.
10. Conlee, R. K., T. L. Berg, D. H. Han, K. P. Kelly, and D. W. Barnett. Cocaine does not alter cardiac glycogen content at rest or during exercise. Metab. Clin. Exp. 38: 1039-1041, 1989.
11. Fisher, E. H., M. G. Heilmeyer, Jr., and R. H. Haschke. Phosphorylase and the control of glycogen degradation. Curr. Top. Cell. Regul. 4: 211-251, 1971.
12. Harms, P. G., and S. R. Ojeda. A rapid and simple procedure for chronic cannulation of the rat jugular vein. J. Appl. Physiol. 36: 391-392, 1974.
13. Kiritsy-Roy, J. A., J. B. Halter, S. M. Gordon, M. J. Smith, and L. C. Terry. Role of the central nervous system in hemodynamic and sympathoadrenal responses to cocaine in rats. J. Pharmacol. Exp. Ther. 225: 154-160, 1990.
14. Kloner, R. A., S. Hale, K. Alker, and S. Rexkalla. The effects of acute and chronic cocaine use on the heart. Circulation 85: 407-419, 1992.
15. Laird, N. M., and J. H. Ware. Random-effects models for longitudinal data. Biometrics 38: 963-974, 1982.
16. Langer, S. Z., and M. A. Enero. The potentiation of responses to adrenergic nerve stimulation in the presence of cocaine: its relationship to the metabolic fate of released norepinephrine. J. Pharmacol Exp. Ther. 91: 431-443, 1974.
17. Lau, C. E., F. Ma, and J. L. Falk. Simultaneous determination of cocaine and its metabolites with caffeine in rat serum microsamples by high-performance liquid chromatography. J. Chromatogr. 532: 95-103, 1990.
18. Leon-Velarde, F., L. Huicho, and C. C. Monge. Effects of cocaine on oxygen consumption and mitochondrial respiration in normoxic and hypoxic mice. Life Sci. 50: 213-218, 1991.
19. 3H]-cocaine in rat brain. Experientia Basel 30: 1312-1314, 1974.
20. 3H]-cocaine in acutely and chronically treated rats. J. Pharmacol. Exp. Ther. 196: 556-569, 1976.
21. ++ release in length clamped ferret papillary muscle (Abstract). Circulation 80, Suppl. II: II16, 1984.
22. Pawelczyk, J. A. Neural control of skin and muscle blood flow during exercise and thermal stress. In: Perspectives in Exercise Science and Sports Medicine: Vol. 6, Exercise, Heat, and Thermo-regulation, edited by C. V. Gisolfi, D. R. Lamb, and E. R. Nadel. Dubuque, IA: Brown and Benchmark, 1993, vol. 6, p. 119-177.
23. Pitts, D. K., and J. Marwah. Autonomic actions of cocaine. Can. J Physiol. Pharmacol. 67: 1168-1176, 1989.
24. Ritchie, J. M., and N. M. Greene. Local anesthetics. In: The Pharmacological Basis of Therapeutics (8th ed.), edited by A. G. Gilman, T. W. Rall, A. S. Nies, and P. Taylor. New York: Pergamon, 1990, p. 311-331.
25. Scheurink, A. J. W., A. B. Steffens, H. Bouritius, G. H. Dreteler, R. Bruntink, R. Remie, and J. Zaagsma. Adrenal and sympathetic catecholamines in exercising rats. Am. J. Physiol. 256 (Regulatory Integrative Comp. Physiol. 25): R155-R160, 1989.
26. Sesotoft, L., J. Trap-Jensen, J. Lyngsoe, J. P. Clausen, J. J. Holst, S. L. Nielsen, J. F. Rehfeld, and O. B. Schaffalitzky de Muckadell. Regulation of gluconeogenesis and ketogenesis during rest and exercise in diabetic subjects and normal man. Clin. Sci. Mol. Med. 53: 411-418, 1977.
27. Shuster, L. Pharmacokinetics, metabolism, and disposition of cocaine. In: Cocaine. Pharmacology, Physiology, and Clinical Strategies, edited by J. M. Lakoski, M. P. Galloway, and F. J. White. Boca Raton, FL: CRC, 1992, p. 1-14.
28. Sloan, M. A., and T. A. Mattioni. Concurrent myocardial and cerebral infarctions after intranasal cocaine use. Stroke 23: 427-430, 1992.
29. Smedes, F., J. C. Kraak, and H. Poppe. Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline, and dopamine from plasma and urine. J. Chromatogr. 231: 25-39, 1982.
30. Steffens, A. B. A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal. Physiol. Behav. 4: 215-225, 1969.
31. Stewart, D. J., T. Inaba, M. Lucassen, and W. Kalow. Cocaine and norcocaine hydrolysis by liver and serum esterases. Pharmacol. Ther. 25: 464-468, 1979.
32. Trendelenburg, U. The supersensitivity caused by cocaine. J. Pharmacol. Exp. Ther. 125: 55-65, 1959.
33. Wilkerson, R. D. Cardiovascular effects of cocaine in conscious dogs: importance of fully functional autonomic and central nervous systems. J. Pharmacol Exp. Ther. 246: 466-471, 1988.
34. Winder, W. W., and H. T. Yang. Blood collection and processing for measurement of catecholamines in exercising rats. J. Appl. Physiol. 63: 418-420, 1987.
35. Winder, W. W., H T. Yang, A. W. Jaussi, and C. R. Hopkins. Epincphrine, glucose, and lactate infusion in exercising adrenodemedullated rats. J. Appl. Physiol 62: 1442-1447, 1987.