-
1
-
-
0031916812
-
Complex I defect in muscle from patients with Huntington's disease
-
Arenas J, Campos Y, Ribacoba R, Martin MA, Rubio JC, Ablanedo P, Cabello A (1998) Complex I defect in muscle from patients with Huntington's disease. Ann Neurol 43: 397-400
-
(1998)
Ann Neurol
, vol.43
, pp. 397-400
-
-
Arenas, J.1
Campos, Y.2
Ribacoba, R.3
Martin, M.A.4
Rubio, J.C.5
Ablanedo, P.6
Cabello, A.7
-
2
-
-
0028077894
-
Neurochemistry and toxin models in Huntingtons disease
-
Beal MF (1994) Neurochemistry and toxin models in Huntingtons disease. Curr Opin Neurol 7: 542-547
-
(1994)
Curr Opin Neurol
, vol.7
, pp. 542-547
-
-
Beal, M.F.1
-
3
-
-
0033286594
-
Mitochondria, NO and neurodegeneration
-
Beal MF (1999) Mitochondria, NO and neurodegeneration. Biochem Soc Symp 66: 43-54
-
(1999)
Biochem Soc Symp
, vol.66
, pp. 43-54
-
-
Beal, M.F.1
-
4
-
-
0030803457
-
Mitochondrial dysfunction in neurodegeneration
-
Cooper JM, Schapira AH (1997) Mitochondrial dysfunction in neurodegeneration. J Bioenerg Biomembr 29: 175-183
-
(1997)
J Bioenerg Biomembr
, vol.29
, pp. 175-183
-
-
Cooper, J.M.1
Schapira, A.H.2
-
5
-
-
0036523110
-
Therapeutic effects of coenzyme Q(10) and remacemide in transgenic mouse models of Huntington's disease
-
Ferrante RJ, Andreassen OA, Dedeoglu A, Ferrante KL, Jenkins BG, Hersch SM, Beal MF (2002) Therapeutic effects of coenzyme Q(10) and remacemide in transgenic mouse models of Huntington's disease. J Neurosci 22: 1592-1599
-
(2002)
J Neurosci
, vol.22
, pp. 1592-1599
-
-
Ferrante, R.J.1
Andreassen, O.A.2
Dedeoglu, A.3
Ferrante, K.L.4
Jenkins, B.G.5
Hersch, S.M.6
Beal, M.F.7
-
6
-
-
0030069713
-
Relationship between trinucleotide repeats and neuropathological changes in Huntington's disease
-
Furtado S, Suchowersky O, Rewcastle B, Graham L, Klimek ML, Garber A (1996) Relationship between trinucleotide repeats and neuropathological changes in Huntington's disease. Ann Neurol 39: 132-136
-
(1996)
Ann Neurol
, vol.39
, pp. 132-136
-
-
Furtado, S.1
Suchowersky, O.2
Rewcastle, B.3
Graham, L.4
Klimek, M.L.5
Garber, A.6
-
7
-
-
0033969735
-
Altered redox state of platelet coenzyme Q(10) in Parkinson's disease
-
Götz ME, Gerstner A, Harth R, Dirr A, Janetzky B, Kuhn W, Riederer P, Gerlach M (2000) Altered redox state of platelet coenzyme Q(10) in Parkinson's disease. J Neural Transm 107: 41-48
-
(2000)
J Neural Transm
, vol.107
, pp. 41-48
-
-
Götz, M.E.1
Gerstner, A.2
Harth, R.3
Dirr, A.4
Janetzky, B.5
Kuhn, W.6
Riederer, P.7
Gerlach, M.8
-
8
-
-
0029875381
-
Mitochondrial defect in Huntington's disease on caudate nucleus
-
Gu M, Gash MT, Mann VM, JavoyAgid F, Cooper JM, Schapira AHV (1996) Mitochondrial defect in Huntington's disease on caudate nucleus. Ann Neurol 39: 385-389
-
(1996)
Ann Neurol
, vol.39
, pp. 385-389
-
-
Gu, M.1
Gash, M.T.2
Mann, V.M.3
Javoyagid, F.4
Cooper, J.M.5
Schapira, A.H.V.6
-
9
-
-
85009332113
-
Unified Huntington's Disease Rating Scale: Reliability and consistency
-
Huntington Study Group (1996) Unified Huntington's Disease Rating Scale: reliability and consistency. Mov Disord 11: 136-142
-
(1996)
Mov Disord
, vol.11
, pp. 136-142
-
-
-
10
-
-
4544352608
-
Effect of coenzyme Q(10) on energy metabolism in aged rats with Huntington's disease
-
Kasparova S, Sumbalova Z, Kucharska J, Bystricky P, Mlynarik V, Gvozdjakova A (2002) Effect of coenzyme Q(10) on energy metabolism in aged rats with Huntington's disease. J Mol Cell Cardiol 34: A84
-
(2002)
J Mol Cell Cardiol
, vol.34
-
-
Kasparova, S.1
Sumbalova, Z.2
Kucharska, J.3
Bystricky, P.4
Mlynarik, V.5
Gvozdjakova, A.6
-
11
-
-
0034799214
-
A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease
-
Keene CD, Rodrigues CMP, Eich T, Linehan-Stieers C, Abt A, Kren BT, Steer CJ, Low WC (2001) A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease. Exp Neurol 171: 351-360
-
(2001)
Exp Neurol
, vol.171
, pp. 351-360
-
-
Keene, C.D.1
Rodrigues, C.M.P.2
Eich, T.3
Linehan-Stieers, C.4
Abt, A.5
Kren, B.T.6
Steer, C.J.7
Low, W.C.8
-
12
-
-
85009226418
-
A randomized, placebo-controlled trial of coenzyme Q(10) and remacemide in Huntington's disease
-
Kieburtz K, Koroshetz W, McDermott M, Beal MF, Greenamyre JT, Ross CA, Shoulson I, Cudkowicz ME, Sexton P, Skeuse C, Rosas D, Jenkins B, Rosenblatt A, Sherr M, Hersch S, Cellar J, Guttman M, Brown C, Como PG, Marshall F, DeMarcaida JA, Zimmerman C, Marder K, Moskowitz C, Polanco C, Beltre J, Shannon K, Jaglin JA, Niederman F, Ashizawa T, Hunter C, Hunter C, Hauser R, Walker A, Gauger L, Hahn MA, Delgado H, Dawson T, Siemers E, Seeberger L, Dingmann C, Dubinsky R, Gray C, Weiner WJ, Rodriguez-Batemen D, Albin RL, Wernette K, Harrison M, Rost-Ruffner E, Paulsen J, Rodnitzky RL, Dobson J, Vining L, Suchowersky O, Pantella C, Saint-Hilaire MH, Furtado J, Martin W, Wieler M, Walker F, Hunt V, Raymond L, Almqvist E, Rubin A, Blair B, Marek K, Caplan K, Baker D, Bracht A, Casaceli C, Orme C, Rudolph A, Rumfola L, Schifitto G, Shinaman A, Sulimowicz K, Watts A, Eapen S, Zhang L (2001) A randomized, placebo-controlled trial of coenzyme Q(10) and remacemide in Huntington's disease. Neurology 57: 397-404
-
(2001)
Neurology
, vol.57
, pp. 397-404
-
-
Kieburtz, K.1
Koroshetz, W.2
McDermott, M.3
Beal, M.F.4
Greenamyre, J.T.5
Ross, C.A.6
Shoulson, I.7
Cudkowicz, M.E.8
Sexton, P.9
Skeuse, C.10
Rosas, D.11
Jenkins, B.12
Rosenblatt, A.13
Sherr, M.14
Hersch, S.15
Cellar, J.16
Guttman, M.17
Brown, C.18
Como, P.G.19
Marshall, F.20
DeMarcaida, J.A.21
Zimmerman, C.22
Marder, K.23
Moskowitz, C.24
Polanco, C.25
Beltre, J.26
Shannon, K.27
Jaglin, J.A.28
Niederman, F.29
Ashizawa, T.30
Hunter, C.31
Hunter, C.32
Hauser, R.33
Walker, A.34
Gauger, L.35
Hahn, M.A.36
Delgado, H.37
Dawson, T.38
Siemers, E.39
Seeberger, L.40
Dingmann, C.41
Dubinsky, R.42
Gray, C.43
Weiner, W.J.44
Rodriguez-Batemen, D.45
Albin, R.L.46
Wernette, K.47
Harrison, M.48
Rost-Ruffner, E.49
Paulsen, J.50
Rodnitzky, R.L.51
Dobson, J.52
Vining, L.53
Suchowersky, O.54
Pantella, C.55
Saint-Hilaire, M.H.56
Furtado, J.57
Martin, W.58
Wieler, M.59
Walker, F.60
Hunt, V.61
Raymond, L.62
Almqvist, E.63
Rubin, A.64
Blair, B.65
Marek, K.66
Caplan, K.67
Baker, D.68
Bracht, A.69
Casaceli, C.70
Orme, C.71
Rudolph, A.72
Rumfola, L.73
Schifitto, G.74
Shinaman, A.75
Sulimowicz, K.76
Watts, A.77
Eapen, S.78
Zhang, L.79
more..
-
13
-
-
0031044805
-
Energy metabolism defects in Huntington's disease and effects of coenzyme Q(10)
-
Koroshetz WJ, Jenkins BG, Rosen BR, Beal MF (1997) Energy metabolism defects in Huntington's disease and effects of coenzyme Q(10). Ann Neurol 41: 160-165
-
(1997)
Ann Neurol
, vol.41
, pp. 160-165
-
-
Koroshetz, W.J.1
Jenkins, B.G.2
Rosen, B.R.3
Beal, M.F.4
-
14
-
-
0032555066
-
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
-
Matthews RT, Yang L, Browne S, Baik M, Beal MF (1998) Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci USA 95: 8892-8897
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8892-8897
-
-
Matthews, R.T.1
Yang, L.2
Browne, S.3
Baik, M.4
Beal, M.F.5
-
15
-
-
0030869160
-
Inhibition of complex I by neuroleptics in normal human brain cortex parallels the extrapyramidal toxicity of neuroleptics
-
Maurer I, Moller HJ (1997) Inhibition of complex I by neuroleptics in normal human brain cortex parallels the extrapyramidal toxicity of neuroleptics. Mol Cell Biochem 174: 255-259
-
(1997)
Mol Cell Biochem
, vol.174
, pp. 255-259
-
-
Maurer, I.1
Moller, H.J.2
-
16
-
-
0037426566
-
Coenzyme Q(10) supplementation provides mild symptomatic benefit in patients with Parkinson's disease
-
Müller T, Büttner T, Gholipour AF, Kuhn W (2003) Coenzyme Q(10) supplementation provides mild symptomatic benefit in patients with Parkinson's disease. Neurosci Lett 341: 201-204
-
(2003)
Neurosci Lett
, vol.341
, pp. 201-204
-
-
Müller, T.1
Büttner, T.2
Gholipour, A.F.3
Kuhn, W.4
-
17
-
-
0032589681
-
Coenzyme Q10 in health and disease
-
Overvad K, Diamant B, Holm L, Holmer G, Mortensen SA, Stender S (1999) Coenzyme Q10 in health and disease. Eur J Clin Nutr 53: 764-770
-
(1999)
Eur J Clin Nutr
, vol.53
, pp. 764-770
-
-
Overvad, K.1
Diamant, B.2
Holm, L.3
Holmer, G.4
Mortensen, S.A.5
Stender, S.6
-
18
-
-
0035964234
-
Clinical markers of early disease in persons near onset of Huntington's disease
-
Paulsen JS, Zhao H, Stout JC, Brinkman RR, Guttman M, Ross CA, Como P, Manning C, Hayden MR, Shoulson I (2001) Clinical markers of early disease in persons near onset of Huntington's disease. Neurology 57: 658-662
-
(2001)
Neurology
, vol.57
, pp. 658-662
-
-
Paulsen, J.S.1
Zhao, H.2
Stout, J.C.3
Brinkman, R.R.4
Guttman, M.5
Ross, C.A.6
Como, P.7
Manning, C.8
Hayden, M.R.9
Shoulson, I.10
-
19
-
-
0030919726
-
CAG repeat number governs the development rate of pathology in Huntington's disease
-
Penney Jr JB, Vonsattel JP, MacDonald ME, Gusella JF, Myers RH (1997) CAG repeat number governs the development rate of pathology in Huntington's disease. Ann Neurol 41: 689-692
-
(1997)
Ann Neurol
, vol.41
, pp. 689-692
-
-
Penney Jr., J.B.1
Vonsattel, J.P.2
MacDonald, M.E.3
Gusella, J.F.4
Myers, R.H.5
-
20
-
-
0027487511
-
Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity
-
Przedborski S, Jackson-Lewis V, Muthane U, Jiang H, Ferreira M, Naini AB, Fahn S (1993) Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity. Ann Neurol 34: 715-723
-
(1993)
Ann Neurol
, vol.34
, pp. 715-723
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Muthane, U.3
Jiang, H.4
Ferreira, M.5
Naini, A.B.6
Fahn, S.7
-
21
-
-
0033054555
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
-
Schilling G, Becher MW, Sharp AH, Jinnah HA, Duan K, Kotzuk JA, Slunt HH, Ratovitski T, Cooper JK, Jenkins NA, Copeland NG, Price DL, Ross CA, Borchelt DR (1999) Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Hum Mol Genet 8: 397-407
-
(1999)
Hum Mol Genet
, vol.8
, pp. 397-407
-
-
Schilling, G.1
Becher, M.W.2
Sharp, A.H.3
Jinnah, H.A.4
Duan, K.5
Kotzuk, J.A.6
Slunt, H.H.7
Ratovitski, T.8
Cooper, J.K.9
Jenkins, N.A.10
Copeland, N.G.11
Price, D.L.12
Ross, C.A.13
Borchelt, D.R.14
-
22
-
-
0030612117
-
Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
-
Shults CW, Haas RH, Passov D, Beal MF (1997) Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol 42: 261-264
-
(1997)
Ann Neurol
, vol.42
, pp. 261-264
-
-
Shults, C.W.1
Haas, R.H.2
Passov, D.3
Beal, M.F.4
-
23
-
-
0036771852
-
Effects of coenzyme Q(10) in early Parkinson disease - Evidence of slowing of the functional decline
-
Shults CW, Oakes D, Kieburtz K, Beal MF, Haas R, Plumb S, Juncos BL, Nutt J, Shoulson I, Carter J, Kompoliti K, Perlmutter JS, Reich S, Stern M, Watts RL, Kurlan R, Molho E, Harrison M, Lew M (2002) Effects of coenzyme Q(10) in early Parkinson disease - Evidence of slowing of the functional decline. Arch Neurol 59: 1541-1550
-
(2002)
Arch Neurol
, vol.59
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
Beal, M.F.4
Haas, R.5
Plumb, S.6
Juncos, B.L.7
Nutt, J.8
Shoulson, I.9
Carter, J.10
Kompoliti, K.11
Perlmutter, J.S.12
Reich, S.13
Stern, M.14
Watts, R.L.15
Kurlan, R.16
Molho, E.17
Harrison, M.18
Lew, M.19
-
24
-
-
0027495547
-
Smoking and mitochondrial function: A model for environmental toxins
-
Smith PR, Cooper JM, Govan GG, Harding AE, Schapira AH (1993) Smoking and mitochondrial function: a model for environmental toxins. Q J Med 86: 657-660
-
(1993)
Q J Med
, vol.86
, pp. 657-660
-
-
Smith, P.R.1
Cooper, J.M.2
Govan, G.G.3
Harding, A.E.4
Schapira, A.H.5
-
25
-
-
0033286630
-
Secondary abnormalities of mitochondrial DNA associated with neurodegeneration
-
Tabrizi SJ, Schapira AHV (1999b) Secondary abnormalities of mitochondrial DNA associated with neurodegeneration. Biochem Soc Symp 66: 99-110
-
(1999)
Biochem Soc Symp
, vol.66
, pp. 99-110
-
-
Tabrizi, S.J.1
Schapira, A.H.V.2
-
27
-
-
0032900574
-
Biochemical abnormalities and excitotoxicity in Huntington's disease brain
-
Tabrizi SJ, Cleeter MWJ, Xuereb J, Taanman JW, Cooper JM, Schapira AHV (1999a) Biochemical abnormalities and excitotoxicity in Huntington's disease brain. Ann Neurol 45: 25-32
-
(1999)
Ann Neurol
, vol.45
, pp. 25-32
-
-
Tabrizi, S.J.1
Cleeter, M.W.J.2
Xuereb, J.3
Taanman, J.W.4
Cooper, J.M.5
Schapira, A.H.V.6
-
28
-
-
0033982887
-
Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse
-
Tabrizi SJ, Workman J, Hart PE, Mangiarini L, Mahal A, Bates G, Cooper JM, Schapira AHV (2000) Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse. Ann Neurol 47: 80-86
-
(2000)
Ann Neurol
, vol.47
, pp. 80-86
-
-
Tabrizi, S.J.1
Workman, J.2
Hart, P.E.3
Mangiarini, L.4
Mahal, A.5
Bates, G.6
Cooper, J.M.7
Schapira, A.H.V.8
-
29
-
-
4243749997
-
Creatine therapy for Huntington's disease (HD): Clinical and-(31)phosphorous magnetic resonance spectroscopy (P-31 MRS) findings in a one year pilot
-
Tabrizi SJ, Rajagopalan B, Styles P, Manners D, Schapira AH, Warner TT (2002) Creatine therapy for Huntington's disease (HD): clinical and-(31)phosphorous magnetic resonance spectroscopy (P-31 MRS) findings in a one year pilot. Mov Disord 17: S319
-
(2002)
Mov Disord
, vol.17
-
-
Tabrizi, S.J.1
Rajagopalan, B.2
Styles, P.3
Manners, D.4
Schapira, A.H.5
Warner, T.T.6
-
30
-
-
0037677341
-
Creatine therapy for Huntington's disease: Clinical and MRS findings in a 1-year pilot study
-
Tabrizi SJ, Blamire AM, Manners DN, Rajagopalan B, Styles P, Schapira AHV, Warner TT (2003) Creatine therapy for Huntington's disease: clinical and MRS findings in a 1-year pilot study. Neurology 61: 141-142
-
(2003)
Neurology
, vol.61
, pp. 141-142
-
-
Tabrizi, S.J.1
Blamire, A.M.2
Manners, D.N.3
Rajagopalan, B.4
Styles, P.5
Schapira, A.H.V.6
Warner, T.T.7
|