T594M mutation of the epithelial sodium channel β-subunit gene in pre-eclampsia and eclampsia in Black South African women

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 111, Issue 9, 2004, Pages 1012-1013

  Pegoraro, R J ^a   Roberts, C B ^a   Rom, L ^a   Moodley, J ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHANNEL;

ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ECLAMPSIA; EPITHELIAL SODIUM CHANNEL BETA SUBUNIT GENE; ETHNIC GROUP; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; MUTATIONAL ANALYSIS; PATHOGENESIS; PREECLAMPSIA; PRIORITY JOURNAL; SOUTH AFRICA;

AFRICAN CONTINENTAL ANCESTRY GROUP; ECLAMPSIA; FEMALE; HUMANS; MUTATION; NERVE TISSUE PROTEINS; POLYMORPHISM, GENETIC; PRE-ECLAMPSIA; PREGNANCY; PROTEIN SUBUNITS; SODIUM CHANNELS; SOUTH AFRICA;

EID: 4544266909     PISSN: 14700328     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2004.00221.x     Document Type: Article

References (6)

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3. Baker EH, Dong YB, Sagnella GA, et al. Association of hypertension with T594M mutation in beta subunit of epithelial sodium channels in black people resident in London. Lancet 1998;35:1388-1392.
4. Su YR, Rutkowski MP, Klanke CA, et al. A novel variant of the β-subunit of the amiloride-sensitive sodium channel in African Americans. J Am Soc Nephrol 1996;7:2543-2549.
5. Dong YB, Phangle-Rhule J, Owusu I, et al. T594M mutation of the β-subunit of the epithelial sodium channel in Ghanaian populations from Kumasi and London and a possible association with hypertension. Genet Test 2001;6:63-65.
6. Rayner BL, Owen EP, King JA, et al. A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension. J Hypertens 2003;21:921-926.