T594M mutation of the β-subunit of the epithelial sodium channel in Ghanaian populations from Kumasi and London and a possible association with hypertension

Genetic Testing

Volumn 6, Issue 1, 2002, Pages 63-65

  Dong, Y B ^a   Plange Rhule, J ^a   Owusu, I ^a   Micah, F ^a   Eastwood, J B ^a   Carter, N D ^a   Saggar Malik, A K ^a   Cappuccio, F P ^a   Jeffery, S ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHANNEL;

ALLELE; ARTICLE; BETA CHAIN; GENE FREQUENCY; GHANA; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MUTATION; NEGRO; UNITED KINGDOM; ADULT; AMINO ACID SUBSTITUTION; EPITHELIUM; ETHNOLOGY; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; METABOLISM; MISSENSE MUTATION;

ADULT; AMINO ACID SUBSTITUTION; EPITHELIUM; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GHANA; HUMAN; HYPERTENSION; LONDON; MALE; MUTATION, MISSENSE; NEGROID RACE; SODIUM CHANNELS; AFRICAN CONTINENTAL ANCESTRY GROUP; HUMANS;

EID: 0036016992     PISSN: 10906576     EISSN: None     Source Type: Journal    
DOI: 10.1089/109065702760093942     Document Type: Article

References (15)

1. Association of hypertension with T594M mutation in beta sub-unit of epithelial sodium channels in black people resident in London
2. Increased sodium channel activity in black people with the T594M epithelial sodium channel mutation
3. Ethnicity and cardiovascular risk: Variations in the people of African ancestry and South Asian origin
4. Prevalence, detection, and management of cardiovascular risk factors in different ethnic groups in south London
5. A population-based survey of cardiovascular risk factors in different ethnic groups. Methods and baseline findings
6. Loss of protein kinase C inhibition in the beta-T594M variant of the amiloride-sensitive Na+ channel
7. T594M and G442V polymorphisms of the sodium channel beta sub-unit and hypertension in a black population
8. Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach
9. Hypertension caused by a truncated epithelial sodium channel gamma sub-unit: Genetic heterogeneity of Liddle syndrome
10. Structural organisation of the gene encoding the alpha-sub-unit of the human amiloride-sensitive epithelial sodium channel
11. Genetic analysis of the beta sub-unit of the epithelial Na+ channel in essential hypertension
12. Liddle's syndrome: Heritable human hypertension caused by mutations in the beta sub-unit of the epithelial sodium channel
13. Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel
14. A novel variant of the beta-sub-unit of the amiloride-sensitive sodium channel in African Americans