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Volumn 6, Issue 5, 2004, Pages 348-354

Advances in the understanding of biology and prognosis in chronic lymphocytic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN KINASE ZAP 70;

EID: 4544260366     PISSN: 15233790     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11912-004-0060-z     Document Type: Review
Times cited : (11)

References (55)
  • 1
    • 0035447386 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia incidence is substantially higher than estimated from tumor registry data
    • Zent CS, Kyasa MJ, Evans R, Schichman SA: Chronic lymphocytic leukemia incidence is substantially higher than estimated from tumor registry data. Cancer 2001, 92:1325-1330.
    • (2001) Cancer , vol.92 , pp. 1325-1330
    • Zent, C.S.1    Kyasa, M.J.2    Evans, R.3    Schichman, S.A.4
  • 3
    • 0034649716 scopus 로고    scopus 로고
    • When and how to treat chronic lymphocytic leukemia
    • Dighiero G, Binet J-L: When and how to treat chronic lymphocytic leukemia. N Engl J Med 2000, 343:1799-1801.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1799-1801
    • Dighiero, G.1    Binet, J.-L.2
  • 4
    • 0042744791 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia patients with highly stable indolent disease show distinctive phenotypic genotypic features
    • Guarini A, Gaidano G, Mauro FR, et al.: Chronic lymphocytic leukemia patients with highly stable and indolent disease show distinctive phenotypic and genotypic features. Blood 2003, 102:1035-1041.
    • (2003) Blood , vol.102 , pp. 1035-1041
    • Guarini, A.1    Gaidano, G.2    Mauro, F.R.3
  • 5
    • 0035871445 scopus 로고    scopus 로고
    • Rituximab using a thrice weekly dosing schedule in B-cell lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
    • Byrd JC, Murphy T, Howard RS, et al.: Rituximab using a thrice weekly dosing schedule in B-cell lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J Clin Oncol 2001, 19:2153-2164.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 2153-2164
    • Byrd, J.C.1    Murphy, T.2    Howard, R.S.3
  • 6
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • Cheson BD, Bennett JM, Grever M, et al.: National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 1996, 87:4990-4997.
    • (1996) Blood , vol.87 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3
  • 7
  • 8
    • 0028064764 scopus 로고
    • A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group
    • Harris N, Jaffe E, Stein H, et al.: A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 1994, 84:1361-1392.
    • (1994) Blood , vol.84 , pp. 1361-1392
    • Harris, N.1    Jaffe, E.2    Stein, H.3
  • 9
    • 0042971643 scopus 로고    scopus 로고
    • B cell chronic lymphocytic leukemia: Lessons learned from studies of the B cell antigen receptor
    • Chiorazzi N, Ferrarini M: B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor. Annu Rev Immunol 2003, 21:841-894.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 841-894
    • Chiorazzi, N.1    Ferrarini, M.2
  • 10
    • 0029990349 scopus 로고    scopus 로고
    • B-Chronic lymphocytic leukemia: A malignancy of anti-self B cells
    • Caligaris-Cappio F: B-Chronic lymphocytic leukemia: a malignancy of anti-self B cells. Blood 1996, 87:2 615-2620.
    • (1996) Blood , vol.87 , Issue.2 , pp. 615-2620
    • Caligaris-Cappio, F.1
  • 11
    • 0017735423 scopus 로고
    • The class of surface immunoglobulin on virgin and memory B lymphocytes
    • Coffman RL, Cohn M: The class of surface immunoglobulin on virgin and memory B lymphocytes. J Immunol 1977, 118:1806-1815.
    • (1977) J. Immunol. , vol.118 , pp. 1806-1815
    • Coffman, R.L.1    Cohn, M.2
  • 12
    • 0028945621 scopus 로고
    • Somatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells
    • Hashimoto S, Dono M, Wakai M, et al.: Somatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells. J Exp Med 1995, 181:1507-1517.
    • (1995) J. Exp. Med. , vol.181 , pp. 1507-1517
    • Hashimoto, S.1    Dono, M.2    Wakai, M.3
  • 13
    • 0036624881 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes
    • Damle RN, Ghiotto F, Valetto A, et al.: B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes. Blood 2002, 99:4087-4093.
    • (2002) Blood , vol.99 , pp. 4087-4093
    • Damle, R.N.1    Ghiotto, F.2    Valetto, A.3
  • 14
    • 0035803464 scopus 로고    scopus 로고
    • Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells
    • Klein U, Tu Y, Stolovitzky G, et al.: Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med 2001, 194:1625-1638.
    • (2001) J. Exp. Med. , vol.194 , pp. 1625-1638
    • Klein, U.1    Tu, Y.2    Stolovitzky, G.3
  • 15
    • 0035803371 scopus 로고    scopus 로고
    • Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
    • Rosenwald A, Alizadeh AA, Widhopf G, et al.: Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001, 194:1639-1647.
    • (2001) J. Exp. Med. , vol.194 , pp. 1639-1647
    • Rosenwald, A.1    Alizadeh, A.A.2    Widhopf, G.3
  • 16
    • 0344729013 scopus 로고    scopus 로고
    • Chlorambucil in indolent chronic lymphocytic leukemia
    • Dighiero G, Maloum K, Desablens B, et al.: Chlorambucil in indolent chronic lymphocytic leukemia. N Engl J Med 1998, 338:1506-1514.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1506-1514
    • Dighiero, G.1    Maloum, K.2    Desablens, B.3
  • 17
    • 0033583824 scopus 로고    scopus 로고
    • Chemotherapeutic options in chronic lymphocytic leukemia: A meta-analysis of the randomized trials CLL Trialists' Collaborative Group
    • Chemotherapeutic options in chronic lymphocytic leukemia: a meta-analysis of the randomized trials. CLL Trialists' Collaborative Group. J Natl Cancer Inst 1999, 91:861-868.
    • (1999) J. Natl. Cancer Inst.
  • 18
    • 0016740933 scopus 로고
    • Clinical staging of chronic lymphocytic leukemia
    • Rai KR, Sawitsky A, Cronkite EP, et al.: Clinical staging of chronic lymphocytic leukemia. Blood 1975, 46:219-234.
    • (1975) Blood , vol.46 , pp. 219-234
    • Rai, K.R.1    Sawitsky, A.2    Cronkite, E.P.3
  • 19
    • 0019427092 scopus 로고
    • A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis
    • Binet JL, Auquier A, Dighiero G, et al.: A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer 1981, 48:198-205.
    • (1981) Cancer , vol.48 , pp. 198-205
    • Binet, J.L.1    Auquier, A.2    Dighiero, G.3
  • 20
    • 0022569746 scopus 로고
    • Lymphocyte doubling time in chronic lymphocytic leukaemia: Analysis of its prognostic significance
    • Montserrat E, Sanchez-Bisono J, Vinolas N, Rozman C: Lymphocyte doubling time in chronic lymphocytic leukaemia: analysis of its prognostic significance. Br J Haematol 1986, 62:567-575.
    • (1986) Br. J. Haematol. , vol.62 , pp. 567-575
    • Montserrat, E.1    Sanchez-Bisono, J.2    Vinolas, N.3    Rozman, C.4
  • 21
    • 0023219896 scopus 로고
    • Bone marrow biopsy in chronic lymphocytic leukemia: A review of its prognostic importance
    • Montserrat E, Rozman C: Bone marrow biopsy in chronic lymphocytic leukemia: a review of its prognostic importance. Blood Cells 1987, 12:315-326.
    • (1987) Blood Cells , vol.12 , pp. 315-326
    • Montserrat, E.1    Rozman, C.2
  • 22
    • 2442548935 scopus 로고    scopus 로고
    • Infections in patients with chronic lymphocytic leukemia
    • edn 2. Edited by Cheson BD. New York: Marcel Dekker
    • Morrison VA: Infections in patients with chronic lymphocytic leukemia. In Chronic Lymphocytic Leukemias, edn 2. Edited by Cheson BD. New York: Marcel Dekker, 2001:505-523.
    • (2001) Chronic Lymphocytic Leukemias , pp. 505-523
    • Morrison, V.A.1
  • 23
    • 0025816949 scopus 로고
    • Cost effectiveness of prophylactic intravenous immune globulin in chronic lymphocytic leukemia
    • Weeks JC, Tierney MR, Weinstein MC: Cost effectiveness of prophylactic intravenous immune globulin in chronic lymphocytic leukemia. N Engl J Med 1991, 325:81-86.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 81-86
    • Weeks, J.C.1    Tierney, M.R.2    Weinstein, M.C.3
  • 24
    • 0031889469 scopus 로고    scopus 로고
    • Impairments in immune cell function in B cell chronic lymphocytic leukemia
    • Bartik MM, Welker D, Kay NE: Impairments in immune cell function in B cell chronic lymphocytic leukemia. Semin Oncol 1998, 25:27-33.
    • (1998) Semin. Oncol. , vol.25 , pp. 27-33
    • Bartik, M.M.1    Welker, D.2    Kay, N.E.3
  • 25
    • 0041422491 scopus 로고    scopus 로고
    • Autoimmune cytopenia does not predict poor prognosis in chronic lymphocytic leukemia/small lymphocytic lymphoma
    • Kyasa MJ, Parrish RS, Schichman SA, Zent CS: Autoimmune cytopenia does not predict poor prognosis in chronic lymphocytic leukemia/small lymphocytic lymphoma. Am J Hematol 2003, 74:1-8.
    • (2003) Am. J. Hematol. , vol.74 , pp. 1-8
    • Kyasa, M.J.1    Parrish, R.S.2    Schichman, S.A.3    Zent, C.S.4
  • 26
    • 0031951887 scopus 로고    scopus 로고
    • Autoimmune disease and chronic lymphocytic leukemia: Autoimmune hemolytic anemia, pure red cell aplasia, and autoimmune thrombocytopenia
    • Diehl L, Ketchum L: Autoimmune disease and chronic lymphocytic leukemia: autoimmune hemolytic anemia, pure red cell aplasia, and autoimmune thrombocytopenia. Semin Oncol 1998, 2180-97.
    • (1998) Semin. Oncol. , pp. 2180-2197
    • Diehl, L.1    Ketchum, L.2
  • 27
    • 1042280347 scopus 로고    scopus 로고
    • Veterans with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) have a markedly increased rate of second malignancy, which is the most common cause of death
    • Kyasa MJ, Hazlett L, Parrish RS, et al.: Veterans with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) have a markedly increased rate of second malignancy, which is the most common cause of death. Leuk Lymphoma 2004, 45:507-513.
    • (2004) Leuk. Lymphoma , vol.45 , pp. 507-513
    • Kyasa, M.J.1    Hazlett, L.2    Parrish, R.S.3
  • 28
    • 0031886848 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia in (Richter's) transformation
    • Giles F, O'Brien S, Keating M: Chronic lymphocytic leukemia in (Richter's) transformation. Semin Oncol 1998, 25:117-125.
    • (1998) Semin. Oncol. , vol.25 , pp. 117-125
    • Giles, F.1    O'Brien, S.2    Keating, M.3
  • 29
    • 0035885968 scopus 로고    scopus 로고
    • Solid tumors after chronic lymphocytic leukemia
    • Hisada M, Biggar R, Greene M, et al.: Solid tumors after chronic lymphocytic leukemia. Blood 2001, 98:1979-1981.
    • (2001) Blood , vol.98 , pp. 1979-1981
    • Hisada, M.1    Biggar, R.2    Greene, M.3
  • 30
    • 0842285686 scopus 로고    scopus 로고
    • Prognosis at diagnosis: Integrating molecular biologic insights into clinical practice for patients with CLL
    • Shanafelt TD, Geyer SM, Kay NE: Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL. Blood 2004, 103:1202-1210.
    • (2004) Blood , vol.103 , pp. 1202-1210
    • Shanafelt, T.D.1    Geyer, S.M.2    Kay, N.E.3
  • 31
    • 0027444652 scopus 로고
    • A predictive model for aggressive non-Hodgkin's lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project
    • A predictive model for aggressive non-Hodgkin's lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project. N Engl J Med 1993, 329:987-994.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 987-994
  • 32
    • 0001547516 scopus 로고    scopus 로고
    • Cell cooperation in the antibody response
    • edn 5. Edited by Roitt I, Brostoff J, Male D. London: Mosby
    • Feldmann M: Cell cooperation in the antibody response. In Immunology, edn 5. Edited by Roitt I, Brostoff J, Male D. London: Mosby; 1998:139-155.
    • (1998) Immunology , pp. 139-155
    • Feldmann, M.1
  • 33
    • 0033567968 scopus 로고    scopus 로고
    • Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F, et al.: Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999, 94:1840-1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3
  • 34
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin T, Davis Z, Gardiner A, et al.: Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999, 94:1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.1    Davis, Z.2    Gardiner, A.3
  • 35
    • 0035679122 scopus 로고    scopus 로고
    • Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia
    • Jelinek DF, Tschumper RC, Geyer SM, et al.: Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia. Br J Haematol 2001, 115:854-861.
    • (2001) Br. J. Haematol. , vol.115 , pp. 854-861
    • Jelinek, D.F.1    Tschumper, R.C.2    Geyer, S.M.3
  • 36
    • 0037103257 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in CLL: Clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors
    • Oscier DG, Gardiner AC, Mould SJ, et al.: Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood 2002, 100:1177-1184.
    • (2002) Blood , vol.100 , pp. 1177-1184
    • Oscier, D.G.1    Gardiner, A.C.2    Mould, S.J.3
  • 37
    • 10744230550 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use homologous CDR3s: Implicating recognition of a common antigen epitope
    • Tobin G, Thunberg U, Johnson A, et al.: Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope. Blood 2003, 101:4952-4957.
    • (2003) Blood , vol.101 , pp. 4952-4957
    • Tobin, G.1    Thunberg, U.2    Johnson, A.3
  • 38
    • 0141790879 scopus 로고    scopus 로고
    • CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells
    • Deaglio S, Capobianco A, Bergui L, et al.: CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells. Blood 2003, 102:2146-2155.
    • (2003) Blood , vol.102 , pp. 2146-2155
    • Deaglio, S.1    Capobianco, A.2    Bergui, L.3
  • 39
    • 0038203261 scopus 로고    scopus 로고
    • The distinct gene expression profiles of chronic lymphocytic leukemia and multiple myeloma suggest different anti-apoptotic mechanisms but predict only some differences in phenotype
    • Zent CS, Zhan F, Schichman SA, et al.: The distinct gene expression profiles of chronic lymphocytic leukemia and multiple myeloma suggest different anti-apoptotic mechanisms but predict only some differences in phenotype. Leuk Res 2003, 27:765-774.
    • (2003) Leuk. Res. , vol.27 , pp. 765-774
    • Zent, C.S.1    Zhan, F.2    Schichman, S.A.3
  • 40
    • 0035412375 scopus 로고    scopus 로고
    • CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia
    • Ibrahim S, Keating M, Do KA, et al.: CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia. Blood 2001, 98:181-186.
    • (2001) Blood , vol.98 , pp. 181-186
    • Ibrahim, S.1    Keating, M.2    Do, K.A.3
  • 41
    • 0036464608 scopus 로고    scopus 로고
    • CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease
    • Hamblin TJ, Orchard JA, Ibbotson RE, et al.: CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood 2002, 99:1023-1029.
    • (2002) Blood , vol.99 , pp. 1023-1029
    • Hamblin, T.J.1    Orchard, J.A.2    Ibbotson, R.E.3
  • 42
    • 0037406968 scopus 로고    scopus 로고
    • ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
    • Crespo M, Bosch F, Villamor N, et al.: ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N Engl J Med 2003, 348:1764-1775.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1764-1775
    • Crespo, M.1    Bosch, F.2    Villamor, N.3
  • 43
    • 10744222814 scopus 로고    scopus 로고
    • ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile
    • Wiestner A, Rosenwald A, Barry TS, et al.: ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 2003, 101:4944-4951.
    • (2003) Blood , vol.101 , pp. 4944-4951
    • Wiestner, A.1    Rosenwald, A.2    Barry, T.S.3
  • 44
    • 0037114744 scopus 로고    scopus 로고
    • Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia
    • Chen L, Widhopf G, Huynh L, et al.: Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood 2002, 100:4609-4614.
    • (2002) Blood , vol.100 , pp. 4609-4614
    • Chen, L.1    Widhopf, G.2    Huynh, L.3
  • 45
    • 1442347535 scopus 로고    scopus 로고
    • Zap-70 is a more reliable marker of disease progression risk than immunoglobulin mutation status in chronic lymphocytic leukemia
    • Rassenti LZ, Huynh L, Toy TL, et al.: Zap-70 is a more reliable marker of disease progression risk than immunoglobulin mutation status in chronic lymphocytic leukemia. Blood 2003, 102:34a.
    • (2003) Blood , vol.102
    • Rassenti, L.Z.1    Huynh, L.2    Toy, T.L.3
  • 46
    • 0842276675 scopus 로고    scopus 로고
    • ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia
    • Durig J, Nuckel H, Cremer M, et al.: ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia. Leukemia 2003, 17:2426-2434.
    • (2003) Leukemia , vol.17 , pp. 2426-2434
    • Durig, J.1    Nuckel, H.2    Cremer, M.3
  • 47
    • 0347318114 scopus 로고    scopus 로고
    • ZAP-70 expression and prognosis in chronic lymphocytic leukaemia
    • Orchard JA, Ibbotson RE, Davis Z,et al.: ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 2004, 363:105-111.
    • (2004) Lancet , vol.363 , pp. 105-111
    • Orchard, J.A.1    Ibbotson, R.E.2    Davis, Z.3
  • 48
    • 4344563250 scopus 로고    scopus 로고
    • Expression of ZAP-70 in both unmutated and mutated leukemic CLL B cells indicates lack of efficacy as a surrogate marker for immunoglobulin mutational status
    • Pittner BT, Tschumper RC, Kimlinger TK, et al.: Expression of ZAP-70 in both unmutated and mutated leukemic CLL B cells indicates lack of efficacy as a surrogate marker for immunoglobulin mutational status. Blood 2003, 102:34a-35a.
    • (2003) Blood , vol.102
    • Pittner, B.T.1    Tschumper, R.C.2    Kimlinger, T.K.3
  • 49
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, et al.: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2002, 99:15524-15529.
    • (2002) Proc. Natl. Acad. Sci. U S A , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 50
    • 0034727833 scopus 로고    scopus 로고
    • Genomic aberrations and survival in chronic lymphocytic leukemia
    • Döhner H, Stilgenbauer S, Benner A, et al.: Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000, 343:1910-1916.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1910-1916
    • Döhner, H.1    Stilgenbauer, S.2    Benner, A.3
  • 51
    • 1542398888 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia with 6q- shows distinct hematological features and intermediate prognosis
    • Cuneo A, Rigolin GM, Bigoni R, et al.: Chronic lymphocytic leukemia with 6q- shows distinct hematological features and intermediate prognosis. Leukemia 2004, 18:476-483.
    • (2004) Leukemia , vol.18 , pp. 476-483
    • Cuneo, A.1    Rigolin, G.M.2    Bigoni, R.3
  • 52
    • 0037541558 scopus 로고    scopus 로고
    • Chromosome anomalies detected by interphase fluorescence in situ hybridization: Correlation with significant biological features of B-cell chronic lymphocytic leukaemia
    • Dewald GW, Brockman SR, Paternoster SF, et al.: Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia. Br J Haematol 2003, 121:287-295.
    • (2003) Br. J. Haematol. , vol.121 , pp. 287-295
    • Dewald, G.W.1    Brockman, S.R.2    Paternoster, S.F.3
  • 53
    • 1842328565 scopus 로고    scopus 로고
    • 11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis
    • Dohner H, Stilgenbauer S, James MR, et al.: 11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood 1997, 89:2516-2522.
    • (1997) Blood , vol.89 , pp. 2516-2522
    • Dohner, H.1    Stilgenbauer, S.2    James, M.R.3
  • 54
    • 11144357657 scopus 로고    scopus 로고
    • Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
    • Lozanski G, Heerema NA, Flinn IW, et al.: Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood 2004, 103:3278-3281.
    • (2004) Blood , vol.103 , pp. 3278-3281
    • Lozanski, G.1    Heerema, N.A.2    Flinn, I.W.3
  • 55
    • 1942459748 scopus 로고    scopus 로고
    • Proteomic analysis of chronic lymphocytic leukemia subtypes with mutated or unmutated Ig VH cenes
    • Cochran DA, Evans CA, Blinco D, et al.: Proteomic analysis of chronic lymphocytic leukemia subtypes with mutated or unmutated Ig VH cenes. Mol Cell Proteomics 2003, 2:1331-1341.
    • (2003) Mol. Cell Proteomics , vol.2 , pp. 1331-1341
    • Cochran, D.A.1    Evans, C.A.2    Blinco, D.3


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